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Condition: Atrial Fibrillation

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Total 17201 results found since Jan 2013.

Novel oral anticoagulants: A focused review for stroke physicians
Novel oral anticoagulants provide an effective and convenient alternative to warfarin for stroke prevention in patients with atrial fibrillation. However, novel anticoagulants also present new challenges for stroke physicians, such as measurement of anticoagulant effect in emergency situations, use of thrombolysis in acute ischemic stroke, optimal timing of introduction of novel anticoagulants following acute ischemic stroke, and management of intracerebral hemorrhage. In this review, we propose pragmatic approaches to dealing with challenging management issues that will face stroke physicians who care for patients with ac...
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Emer R. McGrath, John W. Eikelboom, Moira K. Kapral, Martin J. O'Donnell Tags: Review Source Type: research

Validation of the Totaled Health Risks In Vascular Events (THRIVE) score for outcome prediction in endovascular stroke treatment
ConclusionsThe THRIVE score reliably predicts outcomes after endovascular stroke treatment and may be useful as a clinical prognostic tool and to perform severity adjustments in stroke clinical research.
Source: International Journal of Stroke - August 29, 2012 Category: Neurology Authors: Alexander C. Flint, Hooman Kamel, Vivek A. Rao, Sean P. Cullen, Bonnie S. Faigeles, Wade S. Smith Tags: Research Source Type: research

Venous Thromboembolism in the Get With The Guidelines-Stroke Acute Ischemic Stroke Population: Incidence and Patterns of Prophylaxis
Conclusions: Despite a high overall rate of VTE prophylaxis, VTE was found to occur in approximately 3% of GWTG-S patients. Reported rates of VTE prophylaxis differed among hospitals by region and hospital type, and among patients by age, race, and medical comorbidities.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: G. Logan Douds, Anne S. Hellkamp, DaiWai M. Olson, Gregg C. Fonarow, Eric E. Smith, Lee H. Schwamm, Kevin M. Cockroft Tags: Original Articles Source Type: research

Does the Magnitude of the Electrocardiogram QT Interval Dispersion Predict Stroke Outcome? (P7.154)
CONCLUSIONS: We were unable to demonstrate that QTd is useful in predicting clinical outcome at discharge in AIS.Disclosure: Dr. Lederman has nothing to disclose. Dr. Steinberg has nothing to disclose. Dr. Balucani has nothing to disclose. Dr. Philip has nothing to disclose. Dr. Lazar has nothing to disclose. Dr. Weedon has nothing to disclose. Dr. Mirchandani has nothing to disclose. Dr. Viticchi has nothing to disclose. Dr. Falsetti has nothing to disclose. Dr. Silvestrini has nothing to disclose. Dr. Gugger has nothing to disclose. Dr. Aharonoff has nothing to disclose. Dr. Piran has nothing to disclose. Dr. Adler has n...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Lederman, Y., Steinberg, L., Balucani, C., Philip, C., Lazar, J., Weedon, J., Mirchandani, G., Viticchi, G., Falsetti, L., Silvestrini, M., Gugger, J., Aharonoff, D., Piran, P., Adler, Z., Levine, S. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Brain Natriuretic Peptide in Acute Ischemic Stroke
Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic stroke. We measured serum BNP levels in consecutive patients aged 18 years or older. Stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment criteria. Categorical variables included age, sex, smoking status, alcohol consumption status, hypertension, diabetes mellitus, dyslipidemia...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Kenji Maruyama, Tsuyoshi Shiga, Mutsumi Iijima, Saori Moriya, Satoko Mizuno, Sono Toi, Kotaro Arai, Kyomi Ashihara, Kayoko Abe, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Seven days of non-invasive cardiac monitoring early postischaemic stroke or TIA increases atrial fibrillation detection rate compared with current guideline-based practice
Commentary on: Higgins P, Macfarlane PW, Dawson J, et al.. Non-invasive cardiac event monitoring to detect atrial fibrillation after ischemic stroke: a randomized, controlled trial. Stroke 2013;44:2525–31. Context Atrial fibrillation (AF) is an established risk factor for stroke, and anticoagulation treatment is effective in reducing recurrent stroke risk. Guidelines recommend the use of clinical prediction tools to select patients with AF for anticoagulation therapy. It has long been recognised that paroxysmal AF (PAF) may pose a similar stroke risk to persistent AF, but the association between the duration of PAF a...
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Coutts, S. B., Choi, P. M. C. Tags: EBM Diagnosis, Clinical trials (epidemiology), Drugs: cardiovascular system, Stroke, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Screening (public health) Source Type: research

Peripheral pulse measurement after ischemic stroke: A feasibility study
Conclusion: With a low rate of false-positive results, MPP offers an easy, ubiquitously available, noninvasive, first-step screening tool to guide ECG diagnostics for pAF after ischemic stroke. The data warrant a prospective trial evaluating the efficacy of MPP-guided ECG diagnostics in secondary prevention after stroke, which is now underway. Classification of evidence: This study provides Class I evidence that MPP by patients or relatives accurately distinguishes AF from normal heart rhythm as compared with continuous ECG.
Source: Neurology - August 11, 2014 Category: Neurology Authors: Kallmunzer, B., Bobinger, T., Kahl, N., Kopp, M., Kurka, N., Hilz, M.-J., Marquardt, L., Schwab, S., Kohrmann, M. Tags: Diagnostic test assessment, Stroke prevention, All Cerebrovascular disease/Stroke, Cardiac, Class I, Embolism ARTICLE Source Type: research

Effect of Intravenous Thrombolysis on Stroke Associated with Atrial Fibrillation
Conclusions: These results should encourage the use of IVT in AF-associated strokes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2014 Category: Neurology Authors: Visnja Padjen, Dejana Jovanovic, Ivana Berisavac, Marko Ercegovac, Maja Stefanovic Budimkic, Predrag Stanarcevic, Ljiljana Beslac Bumbasirevic Tags: Original Articles Source Type: research

Eligibility and Preference of New Oral Anticoagulants in Patients With Atrial Fibrillation: Comparison Between Patients With Versus Without Stroke Clinical Sciences
Conclusions— Patients enrolled in RCTs are partly representative of patients with AF in clinical practice. When time in therapeutic range and bleeding tendency with warfarin use were considered, the use of new oral anticoagulants was preferred in patients with stroke than in nonstroke patients, but they were more likely to be excluded in RCTs.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Yoon, C. H., Park, Y. K., Kim, S. J., Lee, M.-j., Ryoo, S., Kim, G.-M., Chung, C.-S., Lee, K. H., Kim, J. S., Bang, O. Y. Tags: Other anticoagulants Clinical Sciences Source Type: research

The Second Elevation of Neuron-Specific Enolase Peak after Ischemic Stroke Is Associated with Hemorrhagic Transformation
Conclusions: Serial NSE analysis during the acute period of ischemic stroke is useful for monitoring hemorrhagic transformation and the blood-brain barrier disruption status.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Bum Joon Kim, Yeon-Jung Kim, Sung Ho Ahn, Na Young Kim, Dong-Wha Kang, Jong S. Kim, Sun U. Kwon Tags: Original Articles Source Type: research

Association Between In-Hospital Mortality and Renal Dysfunction in 186 219 Patients Hospitalized for Acute Stroke in the Emilia-Romagna Region of Italy
Using a regional Italian database, we evaluated the relationship between renal dysfunction and in-hospital mortality (IHM) in patients with acute stroke (ischemic/hemorrhagic). Patients were classified on the basis of renal damage: without renal dysfunction, with chronic kidney disease (CKD), and with end-stage renal disease (ESRD). Of a total of 186 219 patients with a first episode of stroke, 1626 (0.9%) had CKD and 819 (0.4%) had ESRD. Stroke-related IHM (total cases) was independently associated with CKD, ESRD, atrial fibrillation (AF), age, and Charlson comorbidity index (CCI). In patients with ischemic stroke (n = 15...
Source: Angiology - October 20, 2014 Category: Cardiology Authors: Fabbian, F., Gallerani, M., Pala, M., De Giorgi, A., Salmi, R., Dentali, F., Ageno, W., Manfredini, R. Tags: Stroke Source Type: research

Anemia on admission predicts short‐ and long‐term outcomes in patients with acute ischemic stroke
ConclusionAnemia is common among AIS patients and is associated with cardiovascular comorbidities. Low hemoglobin status independently predicts short and long‐term mortality.
Source: International Journal of Stroke - November 27, 2014 Category: Neurology Authors: Haralampos Milionis, Vasileios Papavasileiou, Ashraf Eskandari, Suzette D'Ambrogio‐Remillard, George Ntaios, Patrik Michel Tags: Research Source Type: research

Canadian Stroke Best Practice Recommendations: secondary prevention of stroke guidelines, update 2014
Every year, approximately 62 000 people with stroke and transient ischemic attack are treated in Canadian hospitals. The 2014 update of the Canadian Secondary Prevention of Stroke guideline is a comprehensive summary of current evidence‐based recommendations for clinicians in a range of settings, who provide care to patients following stroke. Notable changes in this 5th edition include an emphasis on treating the highest risk patients who present within 48 h of symptom onset with transient or persistent motor or speech symptoms, who need to be transported to the closest emergency department with capacity for advanced...
Source: International Journal of Stroke - December 23, 2014 Category: Neurology Authors: Shelagh B. Coutts, Theodore H. Wein, M. Patrice Lindsay, Brian Buck, Robert Cote, Paul Ellis, Norine Foley, Michael D. Hill, Sharon Jaspers, Albert Y. Jin, Brenda Kwiatkowski, Carolyn MacPhail, Dana McNamara‐Morse, Michael S. McMurtry, Tania Mysak, Andr Tags: Guidelines Source Type: research

Rates of Ischemic Stroke During Warfarin Treatment for Atrial Fibrillation Brief Reports
Conclusions— In a large cohort of older patients with atrial fibrillation, we observed the highest rate of ischemic stroke in the first 30 days after warfarin initiation. Although causation cannot be established given the observational nature of this study, our findings highlight the need for future research in this population.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Tung, J. M., Mamdani, M. M., Juurlink, D. N., Paterson, J. M., Kapral, M. K., Gomes, T. Tags: Cardiovascular Pharmacology, Anticoagulants, Epidemiology Brief Reports Source Type: research

Effect of Cigarette Smoking on Outcomes of Acute Ischemic Stroke Treated with Intravenous Thrombolysis: Is There Any Paradox in The Brain? (P3.071)
Conclusion: There is no smoker's paradox in ischemic stroke.Disclosure: Dr. Hussein has nothing to disclose. Dr. Niemann has nothing to disclose. Dr. Stuck has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hussein, H., Niemann, N., Stuck, L., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research