Query: stroke

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Condition: Atrial Fibrillation

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Total 7929 results found since Jan 2013.

Use of Warfarin at Discharge Among Acute Ischemic Stroke Patients With Nonvalvular Atrial Fibrillation in China Clinical Sciences
Conclusions— The rate of warfarin use remains low among patients with ischemic stroke and known nonvalvular atrial fibrillation in China. Hospital size and academic status together with patient age, heart failure, heavy alcohol drinking, international normalized ratio in hospital, and stroke severity on admission were each independently associated with the use of warfarin at discharge. There is much room for improvement for secondary stroke prevention in nonvalvular atrial fibrillation patients in China.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Yang, X., Li, Z., Zhao, X., Wang, C., Liu, L., Wang, C., Pan, Y., Li, H., Wang, D., Hart, R. G., Wang, Y., Wang, Y., on behalf of the China National Stroke Registry II Investigators Tags: Anticoagulants, Treatment, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Ischemic Stroke Risk in Patients With Atrial Fibrillation and CHA2DS2-VASc Score of 1: Systematic Review and Meta-Analysis Brief Reports
Conclusions— Our meta-analysis of ischemic stroke risk in atrial fibrillation patients suggests that those with CHA2DS2-VASc score of 1 may be considered for a novel oral anticoagulant, but because of high heterogeneity, the decision should be based on individual patient characteristics.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Joundi, R. A., Cipriano, L. E., Sposato, L. A., Saposnik, G., on behalf of the Stroke Outcomes Research Working Group Tags: Atrial Fibrillation, Meta Analysis, Ischemic Stroke Brief Reports Source Type: research

Underutilization of Ambulatory ECG Monitoring After Stroke and Transient Ischemic Attack: Missed Opportunities for Atrial Fibrillation Detection Clinical Sciences
Conclusions— Less than one third of patients in our cohort received guideline-recommended 24-hour Holter monitoring, and <1% received prolonged ambulatory ECG monitoring. These findings highlight a modifiable evidence-practice gap that likely contributes to an overdiagnosis of strokes as cryptogenic, an underdiagnosis of atrial fibrillation, and missed anticoagulant treatment opportunities for secondary stroke prevention.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Edwards, J. D., Kapral, M. K., Fang, J., Saposnik, G., Gladstone, D. J., Investigators of the Registry of the Canadian Stroke Network Tags: Atrial Fibrillation, Secondary Prevention, Electrocardiology (ECG), Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research

Incident Stroke Is Associated With Common Carotid Artery Diameter and Not Common Carotid Artery Intima-Media Thickness Clinical Sciences
Conclusions— Although common carotid IMT is not associated with stroke, interadventitial diameter of the common carotid artery is independently associated with first-time incident ischemic stroke even after adjusting for IMT. Our hypothesis that this is in part attributable to the effects of exposure to blood pressure needs confirmation by other studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00063440.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Polak, J. F., Sacco, R. L., Post, W. S., Vaidya, D., Arnan, M. K., O'Leary, D. H. Tags: Cerebrovascular disease/stroke, Risk Factors, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

N-Terminal Pro-B-type Natriuretic Peptide and Stroke Risk: The Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— NT-proBNP was a major independent risk marker for stroke. Considering this and other data for stroke, coronary disease, and atrial fibrillation, the clinical use of NT-proBNP measurement in primary prevention settings should be considered.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Cushman, M., Judd, S. E., Howard, V. J., Kissela, B., Gutierrez, O. M., Jenny, N. S., Ahmed, A., Thacker, E. L., Zakai, N. A. Tags: Acute Cerebral Infarction, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Assessing the Performance of the Framingham Stroke Risk Score in the Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— Although higher FSRS was associated with higher stroke risk, the FSRS overestimated the observed stroke rates in this study, particularly in certain subgroups. This may be because of temporal declines in stroke rates, secular trends in prevention treatments, or differences in populations studied. More accurate estimates of event rates are critical for planning research, including clinical trials, and targeting health-care efforts.
Source: Stroke - May 27, 2014 Category: Neurology Authors: McClure, L. A., Kleindorfer, D. O., Kissela, B. M., Cushman, M., Soliman, E. Z., Howard, G. Tags: Risk Factors for Stroke Clinical Sciences Source Type: research

Rivaroxaban for Stroke Prevention in East Asian Patients From the ROCKET AF Trial Clinical Sciences
Conclusions— Observed relative efficacy and safety of rivaroxaban versus warfarin were similar among patients within and outside East Asia. Rivaroxaban, 20 mg once daily, is an alternative to warfarin for stroke prevention in East Asians with nonvalvular atrial fibrillation. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00123456.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Wong, K. S. L., Hu, D. Y., Oomman, A., Tan, R.-S., Patel, M. R., Singer, D. E., Breithardt, G., Mahaffey, K. W., Becker, R. C., Califf, R., Fox, K. A. A., Berkowitz, S. D., Hacke, W., Hankey, G. J., on behalf of The Executive Steering Committee and the RO Tags: Other anticoagulants, Embolic stroke, Anticoagulants Clinical Sciences Source Type: research

High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke Clinical Sciences
Conclusions— Access to nationwide register data shows that AF is more common among patients with ischemic stroke than those previously reported. Few patients with stroke and AF had anticoagulant treatment before the event, and few got it after the event. CHA2DS2-VASc could be a useful monitoring tool to intensify efforts to diagnose AF among patients with cryptogenic stroke.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Friberg, L., Rosenqvist, M., Lindgren, A., Terent, A., Norrving, B., Asplund, K. Tags: Coumarins, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

P-Wave Morphology and the Risk of Incident Ischemic Stroke in the Multi-Ethnic Study of Atherosclerosis Brief Reports
Conclusions— We found an association between baseline P-wave morphology and incident stroke even after accounting for AF. This association may reflect an atrial cardiopathy that leads to stroke in the absence of AF.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Kamel, H., Soliman, E. Z., Heckbert, S. R., Kronmal, R. A., Longstreth, W. T., Nazarian, S., Okin, P. M. Tags: Cerebrovascular disease/stroke, Electrocardiology, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Risk Factors for Stroke Brief Reports Source Type: research

Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke Clinical Sciences
Conclusions— An AF-GRS can identify 20% of individuals who are at 2-fold increased risk for incident AF and at 23% increased risk for ischemic stroke. Targeting diagnostic or therapeutic interventions to this subset may prove clinically useful.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Tada, H., Shiffman, D., Smith, J. G., Sjogren, M., Lubitz, S. A., Ellinor, P. T., Louie, J. Z., Catanese, J. J., Engstrom, G., Devlin, J. J., Kathiresan, S., Melander, O. Tags: Genetics of Stroke Clinical Sciences Source Type: research

Sickle Cell Trait and Incident Ischemic Stroke in the Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— We observed an increased risk of ischemic stroke in blacks with SCT. Further investigation of the incidence and pathophysiology of stroke in patients with SCT is warranted.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Caughey, M. C., Loehr, L. R., Key, N. S., Derebail, V. K., Gottesman, R. F., Kshirsagar, A. V., Grove, M. L., Heiss, G. Tags: Genetics of Stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Derivation and External Validation of a Case Mix Model for the Standardized Reporting of 30-Day Stroke Mortality Rates Clinical Sciences
Conclusions— We have derived and externally validated 2 models to predict mortality in unselected patients with acute stroke using commonly collected clinical variables. In settings where the ability to record the full NIHSS on admission is limited, the level of consciousness component of the NIHSS provides a good approximation of the full NIHSS for mortality prediction.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Bray, B. D., Campbell, J., Cloud, G. C., Hoffman, A., James, M., Tyrrell, P. J., Wolfe, C. D. A., Rudd, A. G., on behalf of the Intercollegiate Stroke Working Party Group Tags: Epidemiology Clinical Sciences Source Type: research

Antithrombotic Therapy After Acute Ischemic Stroke in Patients With Atrial Fibrillation Clinical Sciences
Conclusions— Contrary to current guidelines, 30% of patients with atrial fibrillation and recent IS are not prescribed any OAC therapy on discharge, whereas a further 30% are prescribed combination OAC and antiplatelet therapy. Combination OAC and antiplatelet therapy in patients at high cardiovascular risk requires evaluation in clinical trials, particularly with the newer OACs, given their more favorable risk–benefit ratio compared with warfarin.
Source: Stroke - November 24, 2014 Category: Neurology Authors: McGrath, E. R., Kapral, M. K., Fang, J., Eikelboom, J. W., Conghaile, A. O., Canavan, M., O'Donnell, M. J., on behalf of the Investigators of the Ontario Stroke Registry Tags: Secondary prevention, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs Clinical Sciences Source Type: research

Acute Hospital, Community, and Indirect Costs of Stroke Associated With Atrial Fibrillation: Population-Based Study Clinical Sciences
Conclusions— In our population study, AF-stroke was associated with substantially higher total, acute hospital, nursing home, and general practitioner costs per patient. Targeted programs to identify AF and prevent AF-stroke may have significant economic benefits, in addition to health benefits.
Source: Stroke - November 24, 2014 Category: Neurology Authors: Hannon, N., Daly, L., Murphy, S., Smith, S., Hayden, D., Ni Chroinin, D., Callaly, E., Horgan, G., Sheehan, O., Honari, B., Duggan, J., Kyne, L., Dolan, E., Williams, D., Wiley, M., Kelly, P. J. Tags: Embolic stroke, Primary and Secondary Stroke Prevention, Risk Factors for Stroke Clinical Sciences Source Type: research

Detection of paroxysmal atrial fibrillation in stroke/tia patients.
Authors: Khan M, Miller DJ Abstract One-third of stroke and transient ischemic attack (TIA) are cryptogenic, and paroxysmal atrial fibrillation (PAF) has been suggested as a possible cause for these cryptogenic strokes. Multiple studies have recently evaluated long-term cardiac rhythm monitoring with good yield for PAF. The duration of monitoring varies between studies as well as the qualifying event definition. Moreover, the clinical significance of very brief atrial fibrillation events is unclear in the literature. This paper provides an overview of current advances in the detection of paroxysmal atrial fibrillat...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Stroke prevention: managing modifiable risk factors.
Authors: Di Legge S, Koch G, Diomedi M, Stanzione P, Sallustio F Abstract Prevention plays a crucial role in counteracting morbidity and mortality related to ischemic stroke. It has been estimated that 50% of stroke are preventable through control of modifiable risk factors and lifestyle changes. Antihypertensive treatment is recommended for both prevention of recurrent stroke and other vascular events. The use of antiplatelets and statins has been shown to reduce the risk of recurrent stroke and other vascular events. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are ...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Age- and gender-specific prevalence of risk factors in patients with first-ever ischemic stroke in china.
Conclusion. Our study showed that vascular risk factors had a specific age and gender distribution pattern in Chinese IS patients. Secondary prevention strategy should emphasize on the control of different risk factors based on patient's age and gender. PMID: 22762013 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Embolic Strokes of Undetermined Source in the Athens Stroke Registry: A Descriptive Analysis Clinical Sciences
Conclusions— About 10% of patients with first-ever ischemic stroke met criteria for ESUS; covert paroxysmal AF seems to be a frequent cause of ESUS.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Ntaios, G., Papavasileiou, V., Milionis, H., Makaritsis, K., Manios, E., Spengos, K., Michel, P., Vemmos, K. Tags: Embolic stroke Clinical Sciences Source Type: research

Hospitalization Within the First Year After Stroke: The Dijon Stroke Registry Clinical Sciences
Conclusions— Stroke survivors are at high risk of hospitalization after the episode, and subsequent admission is associated with poor survival, thus highlighting the need for follow-up interventions after discharge to prevent readmission.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Lainay, C., Benzenine, E., Durier, J., Daubail, B., Giroud, M., Quantin, C., Bejot, Y. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Ischemic Stroke Phenotype in Patients With Nonsustained Atrial Fibrillation Clinical Sciences
Conclusions— Clinical features of patients with nonsustained AF exhibited an intermediary phenotype in between patients with persistent/paroxysmal AF and no AF. Furthermore, imaging features did not entirely resemble patterns observed in patients with longer durations of AF.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Arsava, E. M., Bas, D. F., Atalar, E., Has, A. C., Oguz, K. K., Topcuoglu, M. A. Tags: Electrocardiology, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial Clinical Sciences
Conclusions— Among the types of patient in the Third International Stroke Trial, this secondary analysis did not identify any subgroups for whom treatment should be avoided. Given the limitations of the analysis, we found no clear evidence to avoid treatment in patients with prior ischemic stroke, diabetes mellitus, or hypertension. Clinical Trial Registration— URL: http://www.controlled-trials.com. Unique identifier: ISRCTN25765518. http://www.controlled-trials.com/ISRCTN25765518.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Lindley, R. I., Wardlaw, J. M., Whiteley, W. N., Cohen, G., Blackwell, L., Murray, G. D., Sandercock, P. A. G., on behalf of the IST-3 Collaborative Group, Trial Steering Committee, Baigent, Chadwick, Tyrrell, Lowe, Dennis, Innes, Goodare, CT and MR readi Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Atrial Premature Beats Predict Atrial Fibrillation in Cryptogenic Stroke: Results From the EMBRACE Trial Clinical Sciences
Conclusions— Among older cryptogenic stroke or transient ischemic attack patients, the number of APBs on a routine 24-hour Holter ECG was a strong dose-dependent independent predictor of prevalent subclinical AF. Those with frequent APBs have a high probability of AF and represent ideal candidates for prolonged ECG monitoring for AF detection. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00846924.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Gladstone, D. J., Dorian, P., Spring, M., Panzov, V., Mamdani, M., Healey, J. S., Thorpe, K. E., for the EMBRACE Steering Committee and Investigators*, EMBRACE Steering Committee or Operations Committee, Aviv, Boyle, Blakely, Cote, Hall, Kapral, Kozlowski Tags: Electrocardiology, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke Clinical Sciences Source Type: research

Predictors of Finding Occult Atrial Fibrillation After Cryptogenic Stroke Clinical Sciences
Conclusions— Mobile cardiac outpatient telemetry detects AF in a substantial proportion of cryptogenic stroke patients. Age >60 years and radiographic evidence of prior cortical or cerebellar infarction are robust indicators of occult AF. Patients with neither had a low prevalence of AF.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Favilla, C. G., Ingala, E., Jara, J., Fessler, E., Cucchiara, B., Messe, S. R., Mullen, M. T., Prasad, A., Siegler, J., Hutchinson, M. D., Kasner, S. E. Tags: Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Pathology of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Type of Anesthesia and Differences in Clinical Outcome After Intra-Arterial Treatment for Ischemic Stroke Clinical Sciences
Conclusions— Our study suggests that patients with AIS of the anterior circulation undergoing IAT without GA have a higher probability of good clinical outcome compared with patients treated with general anesthesia.
Source: Stroke - April 27, 2015 Category: Neurology Authors: van den Berg, L. A., Koelman, D. L. H., Berkhemer, O. A., Rozeman, A. D., Fransen, P. S. S., Beumer, D., Dippel, D. W., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Brouwer, P. A., Jenniskens, S., Boiten, J., Lycklama a Nijeholt, G. A., Vos Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Left Atrial Enlargement and Stroke Recurrence: The Northern Manhattan Stroke Study Clinical Sciences
Conclusion— Moderate to severe LAE was an independent marker of recurrent cardioembolic or cryptogenic stroke in a multiethnic cohort of ischemic stroke patients. Further research is needed to determine whether anticoagulant use may reduce risk of recurrence in ischemic stroke patients with moderate to severe LAE.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Yaghi, S., Moon, Y. P., Mora-McLaughlin, C., Willey, J. Z., Cheung, K., Di Tullio, M. R., Homma, S., Kamel, H., Sacco, R. L., Elkind, M. S. V. Tags: Embolic stroke Clinical Sciences Source Type: research

Diagnostic Work-Up for Detection of Paroxysmal Atrial Fibrillation After Acute Ischemic Stroke: Cross-Sectional Survey on German Stroke Units Brief Reports
Conclusions— Our survey demonstrates substantial heterogeneity among German SUs on diagnostic work-up for pAF. Future prospective multicenter studies should systematically evaluate the impact of different methods to uncover pAF.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Rizos, T., Quilitzsch, A., Busse, O., Haeusler, K. G., Endres, M., Heuschmann, P., Veltkamp, R. Tags: Acute Stroke Syndromes Brief Reports Source Type: research

Patients With Ischemic Stroke and Incident Atrial Fibrillation: A Nationwide Cohort Study Clinical Sciences
Conclusions— Ischemic stroke was associated with a substantially increased risk of incident AF, particularly among individuals with higher CHADS2 or CHA2DS2-VASc scores. These risk scores seem to be simple tools for identifying patients at higher risk of incident AF after ischemic stroke.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Fauchier, L., Clementy, N., Pelade, C., Collignon, C., Nicolle, E., Lip, G. Y. H. Tags: Arrhythmias, clinical electrophysiology, drugs, Embolic stroke Clinical Sciences Source Type: research

Microbleed Status and 3-Month Outcome After Intravenous Thrombolysis in 717 Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions— Poor outcome or sICH was not associated with CMB presence or burden on pre–intravenous thrombolysis magnetic resonance imaging after adjustment for confounding factors. An individual patient data meta-analysis is needed to determine whether a subgroup of patients with CMBs carries an independent risk of poor outcome that might outweigh the expected benefit of intravenous thrombolysis.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Turc, G., Sallem, A., Moulin, S., Tisserand, M., Machet, A., Edjlali, M., Baron, J.-C., Leclerc, X., Leys, D., Mas, J.-L., Cordonnier, C., Oppenheim, C. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Intracerebral Hemorrhage, Thrombolysis Clinical Sciences Source Type: research

Risk Factors of Ischemic Stroke and Subsequent Outcome in Patients Receiving Hemodialysis Clinical Sciences
Conclusions— Incidence of stroke is high in patients with ESRD on hemodialysis with high case-fatality. Incident hemodialysis patients had the highest stroke incidence. Many, but not all, important risk factors commonly associated with stroke in the general population were not associated with stroke in patients receiving hemodialysis.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Findlay, M. D., Thomson, P. C., Fulton, R. L., Solbu, M. D., Jardine, A. G., Patel, R. K., Stevens, K. K., Geddes, C. C., Dawson, J., Mark, P. B. Tags: Cerebrovascular disease/stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Functional Gain After Inpatient Stroke Rehabilitation: Correlates and Impact on Long-Term Survival Brief Reports
Conclusions— Several factors are independently associated with functional gain after SR. Our findings strongly suggest that the magnitude of functional improvement is a powerful predictor of long-term mortality in patients admitted for SR.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Scrutinio, D., Monitillo, V., Guida, P., Nardulli, R., Multari, V., Monitillo, F., Calabrese, G., Fiore, P. Tags: Other Stroke Treatment - Medical Brief Reports Source Type: research

Electrocardiographic Left Atrial Abnormality and Risk of Stroke: Northern Manhattan Study Clinical Sciences
Conclusions— ECG-defined left atrial abnormality was associated with incident cryptogenic or cardioembolic stroke independently of the presence of AF, suggesting atrial thromboembolism may occur without recognized AF.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Kamel, H., Hunter, M., Moon, Y. P., Yaghi, S., Cheung, K., Di Tullio, M. R., Okin, P. M., Sacco, R. L., Soliman, E. Z., Elkind, M. S. V. Tags: Electrocardiology, Echocardiography, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Incidence of Stroke or Systemic Embolism in Paroxysmal Versus Sustained Atrial Fibrillation: The Fushimi Atrial Fibrillation Registry Clinical Sciences
Conclusions— In this large cohort of Japanese patients with AF, PAF was independently associated with lower incidence of stroke/systemic embolism than sustained AF. This may aid decision making for anticoagulation, especially in those patients with AF with few stroke risk factors. Clinical Trial Registration— URL: http://www.umin.ac.jp/ctr/index.htm. Unique identifier: UMIN000005834.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Takabayashi, K., Hamatani, Y., Yamashita, Y., Takagi, D., Unoki, T., Ishii, M., Iguchi, M., Masunaga, N., Ogawa, H., Esato, M., Chun, Y.-H., Tsuji, H., Wada, H., Hasegawa, K., Abe, M., Lip, G. Y. H., Akao, M. Tags: Atrial Fibrillation, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Rates and Determinants of 5-Year Outcomes After Atrial Fibrillation-Related Stroke: A Population Study Clinical Sciences
Conclusions— AF-stroke is associated with considerable long-term morbidity, fatality, stroke recurrence, and nursing home requirement. Adequately resourced national AF strategies to improve AF detection and prevention are needed.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Hayden, D. T., Hannon, N., Callaly, E., Ni Chroinin, D., Horgan, G., Kyne, L., Duggan, J., Dolan, E., O'Rourke, K., Williams, D., Murphy, S., Kelly, P. J. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Endovascular Treatment for Acute Ischemic Stroke in the Setting of Anticoagulation Brief Reports
Conclusions— Intra-arterial therapy seems to be safe in patients taking OACs; however, our study showed a nonsignificant increase in hemorrhage and mortality with a nonsignificant decrease in good outcomes in comparison with non-OAC patients. Although these nominal differences may have been related to older age and more comorbidities in the OAC group, larger studies are needed to confirm our findings given our limited sample size.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Rebello, L. C., Haussen, D. C., Belagaje, S., Anderson, A., Frankel, M., Nogueira, R. G. Tags: Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Role of Prestroke Vascular Pathology in Long-Term Prognosis After Stroke: The Rotterdam Study Clinical Sciences
Conclusions— One quarter of deaths after stroke could theoretically be prevented with rigorous cardiovascular prevention and treatment, but this should preferably start before stroke occurrence. In addition, research into factors explaining the remaining deaths needs to be encouraged.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Portegies, M. L. P., Bos, M. J., Hofman, A., Heeringa, J., Franco, O. H., Koudstaal, P. J., Ikram, M. A. Tags: Epidemiology, Risk Factors, Mortality/Survival, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Preexisting Heart Disease Underlies Newly Diagnosed Atrial Fibrillation After Acute Ischemic Stroke Clinical Sciences
Conclusions— Stroke patients with nAF and with kAF share common cardiovascular risk factors, have similar echocardiographic findings and suffer equally severe strokes. We conclude that preexisting heart disease is the major cause of AF that is first diagnosed after stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Rizos, T., Horstmann, S., Dittgen, F., Tager, T., Jenetzky, E., Heuschmann, P., Veltkamp, R. Tags: Atrial Fibrillation, Echocardiography, Ischemic Stroke Clinical Sciences Source Type: research

Perceived Unmet Rehabilitation Needs 1 Year After Stroke: An Observational Study From the Swedish Stroke Register Brief Reports
Conclusions— Unfulfilled rehabilitation needs 1 year poststroke are common and associated with high age, dependency, pain, and depression. Long-term follow-up systems should, therefore, be comprehensive and address multiple domains of poststroke problems, rather than having a single-domain focus.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Ullberg, T., Zia, E., Petersson, J., Norrving, B. Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Short Leukocyte Telomere Length Is Associated With Cardioembolic Stroke Risk in Patients With Atrial Fibrillation Brief Reports
Conclusions— Telomere shortening is associated with cardioembolic stroke risk in patients with AF. Prospective studies are encouraged to establish the value of LTL to improve prediction tools to categorize cardioembolic stroke risk in AF.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Allende, M., Molina, E., Gonzalez-Porras, J. R., Toledo, E., Lecumberri, R., Hermida, J. Tags: Atrial Fibrillation, Risk Factors, Genetics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Stroke and Embolic Events in Hypertrophic Cardiomyopathy: Risk Stratification in Patients Without Atrial Fibrillation Clinical Sciences
Conclusions— The incidence of stroke and embolic events was about 1.0% per year in the HCM cohort. AF had not been previously documented before the event in more than half of patients with events. Older age and enlarged left atrial dimension are possible risk factors for embolic events in patients with HCM without documented AF.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Haruki, S., Minami, Y., Hagiwara, N. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Home-based telesurveillance and rehabilitation after stroke: a real-life study.
CONCLUSION: The home-based program was feasible and effective in both sub-acute and chronic post-stroke patients, improving their recovery, and maintaining the benefits reached during inpatient rehabilitation. PMID: 27078116 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - March 31, 2016 Category: Neurology Authors: Bernocchi P, Vanoglio F, Baratti D, Morini R, Rocchi S, Luisa A, Scalvini S Tags: Top Stroke Rehabil Source Type: research

Obstructive Sleep Apnea in Acute Stroke: A Role for Systemic Inflammation Clinical Sciences
Conclusions— Use of bed-side somnography technology revealed that in an unselected sample of patients with acute ischemic stroke, almost 90% had sleep-disordered breathing with third having severe form of the disorder. Sleep-disordered breathing was associated with significantly increased levels of inflammatory biomarkers, providing possible pathophysiological explanation of OSA-associated stroke risk. These results warrant prospective screening of patients with stroke for the presence of sleep-disordered breathing and lay the rationale for an interventional trial.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Ifergane, G., Ovanyan, A., Toledano, R., Goldbart, A., Abu-Salame, I., Tal, A., Stavsky, M., Novack, V. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes Clinical Sciences
Conclusions— AF is associated with an unfavorable 90-day outcome among patients with a CES independent of established risk factors and initial stroke severity. This suggests that AF-specific mechanisms affect CES severity and functional status after CES. If confirmed in future studies, further investigation into the underlying pathophysiological mechanisms may provide novel avenues to AF detection and treatment.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Henninger, N., Goddeau, R. P., Karmarkar, A., Helenius, J., McManus, D. D. Tags: Atrial Fibrillation, Etiology, Ischemic Stroke Clinical Sciences Source Type: research

Cost-Effectiveness of Oral Anticoagulants for Ischemic Stroke Prophylaxis Among Nonvalvular Atrial Fibrillation Patients Clinical Sciences
Conclusions— All the newer oral anticoagulants compared were more effective than adjusted dosed warfarin. Our model showed that apixaban was the most effective anticoagulant in a general atrial fibrillation population and has an incremental cost-effectiveness ratio <$50 000/QALY. For those with higher stroke risk (CHADS2≥3), dabigatran was the most cost-effective treatment option.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Shah, A., Shewale, A., Hayes, C. J., Martin, B. C. Tags: Anticoagulants, Cost-Effectiveness, Ischemic Stroke Clinical Sciences Source Type: research

Impact of Guidelines on Clinical Practice: Intravenous Heparin Use for Acute Ischemic Stroke Clinical Sciences
Conclusions— Use of intravenous heparin for acute ischemic stroke treatment has decreased in Korea, and this change may be attributable to the spread and successful implementation of regional clinical practice guidelines.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Chung, J.-W., Kim, B. J., Han, M.-K., Ko, Y., Lee, S., Kang, K., Park, J.-M., Park, S.-S., Park, T. H., Cho, Y.-J., Hong, K.-S., Lee, K. B., Lee, J., Ryu, W.-S., Kim, D.-E., Nah, H.-W., Kim, D.-H., Cha, J.-K., Kim, J.-T., Cho, K.-H., Choi, J. C., Oh, M.-S Tags: Treatment, Statements and Guidelines, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study Brief Reports
Conclusions— Increased cIMT and presence of carotid plaque are associated with increased risk of ischemic stroke in individuals with AF. Furthermore, they may improve risk prediction of stroke, over and above the CHA2DS2-VASc score.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Bekwelem, W., Jensen, P. N., Norby, F. L., Soliman, E. Z., Agarwal, S. K., Lip, G. Y. H., Pan, W., Folsom, A. R., Longstreth, W. T., Alonso, A., Heckbert, S. R., Chen, L. Y. Tags: Atrial Fibrillation, Risk Factors, Ischemic Stroke, Atherosclerosis Brief Reports Source Type: research

Association Between Midlife Cardiorespiratory Fitness and Risk of Stroke: The Cooper Center Longitudinal Study Clinical Sciences
Conclusions— There is a strong, inverse association between midlife CRF and stroke risk in later life independent of baseline and antecedent burden of risk factors, such as hypertension, diabetes mellitus, and atrial fibrillation.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Pandey, A., Patel, M. R., Willis, B., Gao, A., Leonard, D., Das, S. R., Defina, L., Berry, J. D. Tags: Epidemiology, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Eligibility and Predictors for Acute Revascularization Procedures in a Stroke Center Clinical Sciences
Conclusions— Of patients arriving within 6 hours at a comprehensive stroke center, 10.5% are EVT eligible according to AHA/ASA criteria, 17.7% according to criteria resembling randomized controlled trials, and twice as many patients are IVT eligible (36.2%).
Source: Stroke - June 26, 2016 Category: Neurology Authors: Vanacker, P., Lambrou, D., Eskandari, A., Mosimann, P. J., Maghraoui, A., Michel, P. Tags: Ischemic Stroke Clinical Sciences Source Type: research

Early Rivaroxaban Use After Cardioembolic Stroke May Not Result in Hemorrhagic Transformation: A Prospective Magnetic Resonance Imaging Study Brief Reports
Conclusions— These data support the safety of rivaroxaban initiation ≤14 days of mild–moderate cardioembolic stroke/transient ischemic attack. Magnetic resonance imaging evidence of petechial HT, which is common, does not appear to increase the risk of symptomatic HT.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Gioia, L. C., Kate, M., Sivakumar, L., Hussain, D., Kalashyan, H., Buck, B., Bussiere, M., Jeerakathil, T., Shuaib, A., Emery, D., Butcher, K. Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Poor Outcome of Stroke Patients With Atrial Fibrillation in the Presence of Coexisting Spontaneous Echo Contrast Brief Reports
Conclusions— In the ischemic stroke patients with nonvalvular AF, coexisting SEC was associated with more severe stroke and was predictive of poor long-term functional outcome.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Yoo, J., Song, D., Baek, J.-H., Kim, Y. D., Nam, H. S., Hong, G.-R., Kim, J., Lee, H. S., Heo, J. H. Tags: Atrial Fibrillation, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Stroke in Duchenne Muscular Dystrophy: A Retrospective Longitudinal Study in 54 Patients Brief Reports
Conclusions— This study indicates an increased risk for ischemic strokes in DMD patients. Regular cardiological assessment of all DMD patients is mandatory to evaluate the individual risk profile for cardioembolic events and to adapt therapeutic strategies.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Winterholler, M., Hollander, C., Kerling, F., Weber, I., Dittrich, S., Turk, M., Schroder, R. Tags: Cardiomyopathy, Ischemic Stroke Brief Reports Source Type: research