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Condition: Heart Failure

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Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke
This study aimed to uncover underlying mechanisms and promising intervention targets of heart failure (HF)-related stroke. HF-related dataset GSE42955 and stroke-related dataset GSE58294 were obtained from the Gene Expression Omnibus (GEO) database. Weighted gene co-expression network analysis (WGCNA) was conducted to identify key modules and hub genes. Gene Ontology (GO) and pathway enrichment analyses were performed on genes in the key modules. Genes in HF- and stroke-related key modules were intersected to obtain common genes for HF-related stroke, which were further intersected with hub genes of stroke-related key modu...
Source: J Zhejiang Univ Sci ... - September 13, 2021 Category: Science Authors: Chiyu Liu Sixu Chen Haifeng Zhang Yangxin Chen Qingyuan Gao Zhiteng Chen Zhaoyu Liu Jingfeng Wang Source Type: research