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Total 2719 results found since Jan 2013.
Dyslipidemia
Ann Intern Med. 2023 Jun 13. doi: 10.7326/AITC202306200. Online ahead of print.ABSTRACTDyslipidemia is an important risk factor for coronary artery disease and stroke. All persons with dyslipidemia should be advised to focus on lifestyle interventions, including regular aerobic exercise, a healthy diet, maintenance of a healthy weight, and abstinence from smoking. In addition to lifestyle interventions, lipid-lowering therapy should be considered for persons at moderate to high risk for atherosclerotic cardiovascular disease based on validated risk equations. Statin therapy is the first-line medical treatment for dyslipide...
Source: Annals of Internal Medicine - June 12, 2023 Category: Internal Medicine Authors: Marios Arvanitis Charles J Lowenstein Source Type: research
Melatonin modulates the aggravation of pyroptosis, necroptosis, and neuroinflammation following cerebral ischemia and reperfusion injury in obese rats
This study aimed to investigate the roles of melatonin on pyroptosis, necroptosis, and pro-inflammatory pathways occurring in the I/R brain of obese rats. Male Wistar rats were given a high-fat diet for 16 weeks to induce the obese condition, and then were divided into 4 groups: Sham-operated, I/R treated with vehicle, I/R treated with melatonin (10 mg/kg), and I/R treated with glycyrrhizic acid (10 mg/kg). All drugs were administered via intraperitoneal injection at the onset of reperfusion. The development of neurological deficits, cerebral infarction, histological changes, neuronal death, and glial cell hyperactivation ...
Source: Biochimica et Biophysica Acta - June 11, 2023 Category: Biochemistry Authors: Nuttapong Yawoot Jirakhamon Sengking Piyarat Govitrapong Chainarong Tocharus Jiraporn Tocharus Source Type: research
User-Centered Mobile Applications for Stroke Survivors (MAPPS): A Mixed-Methods Study of Patient Preferences
CONCLUSIONS: SS are willing to adopt mHealth apps that are free of cost and provide technical support. Apps for SS should perform multiple tasks and be of simple design. Greater interest for the app's features among SS of color may provide opportunities to address health inequities.PMID:37295706 | DOI:10.1016/j.apmr.2023.05.009
Source: Health Physics - June 9, 2023 Category: Physics Authors: Srinath Ramaswamy Nadege Gilles Angelika C Gruessner Dee Burton Marilyn A Fraser Sarah Weingast Saroj Kunnakkat Aimee Afable David Kaufman Jonathan Singer Clotilde Balucani Steven R Levine Source Type: research
Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage.
Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news
Legume consumption in adults and risk of cardiovascular disease and type 2 diabetes: a systematic review and meta-analysis
CONCLUSION: Legume consumption was not found to influence risk of CVD and T2D in healthy adult populations with generally low legume consumption. However, protective effects on risk factors, seen in RCTs, lend some support for recommending legume consumption as part of diverse and healthy dietary patterns for prevention of CVD and T2D.PMID:37288088 | PMC:PMC10243120 | DOI:10.29219/fnr.v67.9541
Source: Food and Nutrition Research - June 8, 2023 Category: Nutrition Authors: Birna Thorisdottir Erik Kristoffer Arnesen Linnea B ärebring Jutta Dierkes Christel Lamberg-Allardt Alfons Ramel Bright I Nwaru Fredrik S öderlund Agneta Åkesson Source Type: research
