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Effects of N-Pep-12 dietary supplementation on neurorecovery after ischemic stroke
ConclusionThis exploratory clinical trial indicates a signal for the benefit of dietary supplementation with N-Pep-12 for the enhancement of neurorecovery after supratentorial ischemic stroke.
Source: Neurological Sciences - October 1, 2020 Category: Neurology Source Type: research

Avoiding the Downward Spiral After Stroke: Early Identification and Treatment of Dysphagia
AbstractPurpose of ReviewThis paper reviews recent evidence concerning the epidemiology, evaluation, and treatment of post-stroke dysphagia.Recent FindingsThe large variability in dysphagia severity and outcomes after stroke warrant a comprehensive evaluation and treatment approach. Screening, bedside evaluation, and instrumental assessments should be systematically and consistently used based on clinical presentation and available resources. In addition to traditional methods of diet modification and implementation of strategies and exercises, the use of novel treatments such as biofeedback and noninvasive brain stimulati...
Source: Current Physical Medicine and Rehabilitation Reports - September 22, 2020 Category: Rehabilitation Source Type: research

Dysphagia, Immobility, and Diet Acceptance: Main Factors Associated with Increased Risk of Pressure Injury in Patients Hospitalized after Stroke
OBJECTIVE To determine the predisposing factors for PI in patients hospitalized after stroke. METHODS This 7-day longitudinal study followed up with patients hospitalized after stroke. Assessments included mobility, nutrition, and the presence of dysphagia and anemia. The nutrition evaluation was based on anthropometric, biochemical, and dietary determinants. Pressure injury (PI) risk was assessed via the Braden Scale. Mann-Whitney and Kruskal-Wallis tests were applied. RESULTS Patients who were bedridden showed a greater risk of PI development upon admission (P = .004) and 7 days later (P
Source: Advances in Skin and Wound Care - September 17, 2020 Category: Dermatology Tags: ORIGINAL INVESTIGATIONS Source Type: research

Inactive bowel movement and stroke are associated with increased risks of mild cognitive impairment among community-living Singapore elderly.
Abstract Mild cognitive impairment (MCI), as a preclinical phase of dementia, provides an invaluable time window for intervention. Besides several proposed modifiable risk factors, the associations of MCI with dietary habits and bowel movement are not well clarified. We thus conducted a cross-sectional study of community-living Singapore elderly and focused on the relationship of clinically diagnosed MCI with dietary habits and bowel movement frequencies. The multiple logistic regression results showed that frequent (≥4 days per week) fruit consumption (P = 0.004), active (≥4 days per week) bowel movement with...
Source: Aging - September 8, 2020 Category: Biomedical Science Authors: Huang KY, Tang XY, Yang L, Zhang ZY, Ye KX, Shen QF, Wang X, Zhu XH, Huang XW, Lu GD, Feng L Tags: Aging (Albany NY) Source Type: research

Exosomes derived from bone marrow mesenchymal stem cells harvested from type two diabetes rats promotes neurorestorative effects after stroke in type two diabetes rats.
CONCLUSIONS: T2DM-MSC-Exo treatment for stroke in T2DM rats promotes neurorestorative effects and improves functional outcome. Down regulation of miR-9 expression and increasing its target ABCA1 pathway may contribute partially to T2DM-MSC-Exo treatment induced white matter remodeling and anti-inflammatory responses. PMID: 32889008 [PubMed - as supplied by publisher]
Source: Experimental Neurology - August 31, 2020 Category: Neurology Authors: Venkat P, Zacharek A, Landschoot-Ward J, Wang F, Culmone L, Chen Z, Chopp M, Chen J Tags: Exp Neurol Source Type: research

Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis
This study aimed to determine the impact of iron chelation with deferoxamine (DFX) on (1) cerebral vascularization patterns and (2) functional outcomes after stroke in control and diabetic rats. After 8  weeks of type 2 diabetes induced by a combination of high-fat diet and low-dose streptozotocin, male control and diabetic animals were subjected to thromboembolic middle cerebral artery occlusion (MCAO) and randomized to vehicle, DFX, or tPA/DFX and followed for 14 days with behavioral tests. Vas cular indices (vascular volume and surface area), neurovascular remodeling (AQP4 polarity), and microglia activation were meas...
Source: Translational Stroke Research - August 31, 2020 Category: Neurology Source Type: research

Creating an appropriate adaptation of a healthy lifestyle intervention for people after stroke.
CONCLUSIONS: Feedback from the diverse group of stakeholders provides the basis for modifying an evidence-based healthy lifestyle intervention to meet the unique needs of people after stroke. Future research efforts should examine the efficacy and effectiveness of the adapted program to prevent weight gain after stroke and reduce the risk of chronic conditions including diabetes, metabolic syndrome, and heart disease. PMID: 32813569 [PubMed - as supplied by publisher]
Source: Brain Injury - August 21, 2020 Category: Neurology Tags: Brain Inj Source Type: research

Effects of Ibuprofen during Exertional Heat Stroke in Mice
Purpose We hypothesized that IBU would exacerbate intestinal injury, reduce exercise performance, and increase susceptibility to heat stroke. Methods To test this hypothesis, we administered IBU via diet to male and female C57/BL6J mice, over 48 h before EHS. Susceptibility to EHS was determined by assessing exercise response using a forced running wheel, housed inside an environmental chamber at 37.5°C. Core temperature (Tc) was monitored by telemetry. Mice were allocated into four groups: exercise only (EXC); EHS + IBU; EXC + IBU; and EHS only. Exercise performance and Tc profiles were evaluated and stomachs, intes...
Source: Medicine and Science in Sports and Exercise - August 14, 2020 Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research

Development of a Care Bundle for Stroke Survivors with Psychological Symptoms: Evidence Summary and Delphi Study.
Conclusion: The development of an evidence-based and consensus-based iDAME bundle which integrated western and traditional Chinese medicine intervention was described. Evidence summary made the bundle become scientific, while the Delphi study made it more maneuverable. Based on these results, the bundle would be potentially implemented in stroke patients for their psychological symptoms. PMID: 32714421 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - July 29, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Quick and effective improvement of leucine enriched dietary supplement on malnutrition in acute stroke patients receiving enteral tube feeding
Malnutrition often occurs in acute stroke patients receiving enteral tube feeding (ETF). Unless malnutrition is improved, their clinical outcome is poor. However, strategies to improve malnutrition in these pa...
Source: BMC Emergency Medicine - July 20, 2020 Category: Emergency Medicine Authors: Takahisa Mori and Kazuhiro Yoshioka Tags: Research article Source Type: research

Obesity Drives Delayed Infarct Expansion, Inflammation, and Distinct Gene Networks in a Mouse Stroke Model
AbstractObesity is associated with chronic peripheral inflammation, is a risk factor for stroke, and causes increased infarct sizes. To characterize how obesity increases infarct size, we fed a high-fat diet to wild-type C57BL/6J mice for either 6  weeks or 15 weeks and then induced distal middle cerebral artery strokes. We found that infarct expansion happened late after stroke. There were no differences in cortical neuroinflammation (astrogliosis, microgliosis, or pro-inflammatory cytokines) either prior to or 10 h after stroke, and also no differences in stroke size at 10 h. However, by 3 days after stroke, animals...
Source: Translational Stroke Research - June 24, 2020 Category: Neurology Source Type: research

Influences of Daily Life Habits on Risk Factors of Stroke Based on Decision Tree and Correlation Matrix.
Conclusions: Establishment of a model for stroke risk assessment, analysis of factors influencing risk factors of stroke, analysis of relationships among those factors, and derivation of knowledge-based rules are helpful for prevention and treatment of stroke. PMID: 32565878 [PubMed - in process]
Source: Computational and Mathematical Methods in Medicine - June 24, 2020 Category: Statistics Tags: Comput Math Methods Med Source Type: research

Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study
High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association...
Source: BMC Neurology - June 23, 2020 Category: Neurology Authors: Pablo M. Lavados, Enrico Mazzon, Alexis Rojo, Alejandro M. Brunser and Ver ónica V. Olavarría Tags: Research article Source Type: research

Oropharyngeal dysphagia in stroke: diagnostic and therapeutic aspects.
CONCLUSION: The prevalence of oropharyngeal dysphagia is high after a stroke. Diagnosis should include a clinical evaluation and an instrumental examination, and thus objectively indicate the treatment, which will include compensatory and restorative measures with which to reduce the associated morbidity and mortality. PMID: 32500523 [PubMed - in process]
Source: Revista de Neurologia - June 6, 2020 Category: Neurology Authors: Terré R Tags: Rev Neurol Source Type: research

The Stroke-Induced Increase of Somatostatin-Expressing Neurons is Inhibited by Diabetes: A Potential Mechanism at the Basis of Impaired Stroke Recovery.
Abstract Type 2 diabetes (T2D) hampers recovery after stroke, but the underling mechanisms are mostly unknown. In a recently published study (Pintana et al. in Clin Sci (Lond) 133(13):1367-1386, 2019), we showed that impaired recovery in T2D was associated with persistent atrophy of parvalbumin+ interneurons in the damaged striatum. In the current work, which is an extension of the abovementioned study, we investigated whether somatostatin (SOM)+ interneurons are also affected by T2D during the stroke recovery phase. C57Bl/6j mice were fed with high-fat diet or standard diet (SD) for 12 months and subjected to 30...
Source: Cellular and Molecular Neurobiology - May 22, 2020 Category: Cytology Authors: Chiazza F, Pintana H, Lietzau G, Nyström T, Patrone C, Darsalia V Tags: Cell Mol Neurobiol Source Type: research

Antioxidative effects of a novel dietary supplement Neumentix in a mouse stroke model
Stroke is the leading cause of disability and death worldwide,1 but current available therapies are limited.2 Oxidative stress is the major component of the stroke cascade, especially in the acute phase of an ischemic stroke.3,4 During brain ischemia and reperfusion, reactive oxygen species (ROS), also referred to as oxygen free radicals, are overproduced, while the endogenous antioxidative defense systems are disrupted.5 ROS generates toxic aldehyde 4-hydroxynonenal (4-HNE),6 glycated protein N(epsilon)-(carboxymethyl) lysine (CML),7 and oxidized DNA 8-hydroxy-2-deoxyguanosine (8-OHdG).
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2020 Category: Neurology Authors: Yuki Taira, Toru Yamashita, Yuting Bian, Jingwei Shang, Namiko Matsumoto, Ryo Sasaki, Koh Tadokoro, Emi Nomura, Keiichiro Tsunoda, Yoshio Omote, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Koji Abe Source Type: research

Substitutions between potatoes and other vegetables and risk of ischemic stroke
ConclusionReplacing potatoes with fruiting vegetables was associated with a lower risk of ischemic stroke.
Source: European Journal of Nutrition - April 8, 2020 Category: Nutrition Source Type: research

Preventing protein-energy malnutrition after cortical stroke enhances recovery of symmetry in forelimb use during spontaneous exploration
Applied Physiology, Nutrition, and Metabolism, e-First Articles. Protein-energy malnutrition (PEM) commonly arises after stroke. We investigated the effects of preventing PEM on spontaneous recovery of forelimb use, infarct size, and the acute phase response in the chronic post-stroke period. Male, adult, Sprague –Dawley rats were acclimatized to control diet (12.5% protein), tested for pre-stroke forelimb use symmetry in the cylinder test, and exposed to photothrombotic cortical stroke or sham surgery. Food intake was monitored daily, and body weight weekly. Forelimb use was tested on day 4 after surgery, before assignm...
Source: Applied Physiology, Nutrition, and Metabolism - April 8, 2020 Category: Physiology Authors: Larisa K. Matwee Mariam Alaverdashvili Gillian D. Muir Jonathan P. Farthing Sarah A. Bater Phyllis G. Paterson Source Type: research

Dietary Inflammatory Index and Leukoaraiosis in Patients with Ischemic Stroke
ConclusionsA pro-inflammatory diet pattern, as indicated by higher DII values, appears to be associated with a higher risk of LA. This result suggested that dietary-mediated inflammation may involved in the pathogenesis of LA, which warrant further study.
Source: The Journal of Nutrition, Health and Aging - March 29, 2020 Category: Nutrition Source Type: research

Dietary patterns generated by the Treelet Transform and risk of stroke: a Danish cohort study.
CONCLUSIONS: The results of this study are broadly in line with current recommendations for a healthy diet to prevent stroke. PMID: 32204745 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - March 23, 2020 Category: International Medicine & Public Health Authors: Frederiksen SB, Themsen HH, Overvad K, Dahm CC Tags: Public Health Nutr Source Type: research

Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization
AbstractA disabling consequence of stroke is cognitive impairment, occurring in 12% –48% of patients, for which there is no therapy. A critical barrier is the lack of understanding of how post-stroke cognitive impairment (PSCI) develops. While 70% of stroke victims present with comorbid diseases such as diabetes and hypertension, the limited use of comorbid disease models in prec linical research further contributes to this lack of progress. To this end, we used a translational model of diabetes to study the development of PSCI. In addition, we evaluated the application of compound 21 (C21), an angiotensin II Type 2 rece...
Source: Translational Stroke Research - December 2, 2019 Category: Neurology Source Type: research

The 2-Minute Spontaneous Swallowing Screening Predicts Independence on Enteral Feeding in Patients with Acute Stroke
It is recommended that enteral feeding should be offered to patients with dysphagia estimated to be unable to take adequate diet orally within 7 days of admission after acute stroke, but there is no clear criterion for initiation of enteral feeding. Recent studies have reported that the frequency of spontaneous swallowing is useful in screening for dysphagia in acute stroke. The present study was aimed to investigate whether measurement of frequency of spontaneous swallowing for 2 minutes could predict independence on enteral feeding 1 week after admission in patients with acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 19, 2019 Category: Neurology Authors: Masachika Niimi, Gentaro Hashimoto, Takatoshi Hara, Naoki Yamada, Hiroto Fujigasaki, Takafumi Ide, Masahiro Abo Source Type: research

Napping Once Or Twice A Week Could Lower Heart Attack & Stroke Risk, Study Finds
By Amy Woodyatt, CNN (CNN) — Some good news for nap fanatics — a new study has found that a daytime nap taken once or twice a week could lower the risk of heart attacks or strokes. Researchers from the University Hospital of Lausanne, Switzerland studied the association between napping frequency and duration and the risk of fatal and non-fatal cardiovascular disease complications. Tracking 3,462 people between the ages of 35 and 75 for just over five years, the report authors found that those who indulged in occasional napping — once or twice a week, for between five minutes to an hour — were 48% ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 10, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Heart Attack Stroke Source Type: news

Differences in dietary recall and subjective physical functioning status in stroke survivors with self-reported cognitive impairment.
CONCLUSION: A lower intake of polyunsaturated fat and vitamin B6 may be associated with cognitive function, ultimately affecting physical functioning, post-stroke. It is possible that differing stroke severity and difficulty recalling dietary habits could have affected the present findings. Therefore, further research is needed to determine if interventions designed to modify polyunsaturated fat and vitamin B6 intakes are able to influence cognitive and physical function in stroke survivors with varying degrees of functional and cognitive deficits. PMID: 30907282 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 23, 2019 Category: Neurology Authors: Kelleher JL, Rodriguez AD, McGregor KM, Serra MC Tags: Top Stroke Rehabil Source Type: research

Diet Drinks Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Early Motor-Behavioral Outcome of Ischemic Stroke with Ketogenic Diet Preconditioning: Interventional Animal Study
Background: Cerebral stroke, with ischemic stroke being its most common type, is the leading cause of chronic disability. The ketogenic diet has been used for treating seizures for centuries and has been considered to be a treatment for other neurologic diseases in recent years. The goal of this study is to evaluate the effects of ketogenic diet preconditioning on the early motor-behavior outcome of rats with induced cerebral ischemic stroke. Methods: Twenty-four rats were surveyed in 3 groups of Main, Control, and Sham.
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2019 Category: Neurology Authors: Sheida Shaafi, Mirmohsen Sharifi-Bonab, Neda Ghaemian, Mohaddeseh Mokhtarkhani, Hossen Akbari Source Type: research

Dietary Practices Among Stroke-survivors —Racial/Ethnic Differences
The objective of this analyzes was therefore to examine racial/ ethnic differences in nutrition activities among stroke survivors using data from the National Health and Nutrition Examination Surveys.
Source: Journal of Stroke and Cerebrovascular Diseases - August 16, 2018 Category: Neurology Authors: Oyinlola T. Babatunde, Patrick M. Briley, Brandi M. White, Xiangming Fang, Charles Ellis Source Type: research

Longitudinal Change of Perceived Salt Intake and Stroke Risk in a Chinese Population Clinical Sciences
Conclusions—Change in salt intake was associated with the stroke risk. These data support the dietary recommendation to the reduction of salt intake.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Yun Li, Zhe Huang, Cheng Jin, Aijun Xing, Yesong Liu, Chunmei Huangfu, Alice H. Lichtenstein, Katherine L. Tucker, Shouling Wu, Xiang Gao Tags: Diet and Nutrition, Epidemiology, Lifestyle, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Impact of angiotensin-converting enzyme inhibition on platelet tissue factor expression in stroke-prone rats
Conclusion: The current study shows for the first time that in hypertension the number of TF-positive megakaryocytes increases thus releasing in the circulation more platelets carrying a functionally active TF. AngII stimulates platelets to express TF.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit
AbstractCough reflex testing has been evaluated as a component of the clinical swallowing assessment as a means of identifying patients at risk of aspiration during swallowing. A previous study by our research group found good sensitivity and specificity of the cough reflex test for identifying patients at risk of aspiration post-stroke, yet its use did not decrease pneumonia rates, contrary to previous reports. The aim of this study was to expand on our earlier work by implementing a clinical management protocol incorporating cough reflex testing within the same healthcare setting and compare patient outcomes to those fro...
Source: Translational Stroke Research - March 30, 2018 Category: Neurology Source Type: research

Protein-Energy Malnutrition Exacerbates Stroke-Induced Forelimb Abnormalities and Dampens Neuroinflammation
AbstractProtein-energy malnutrition (PEM) pre-existing at stroke onset is believed to worsen functional outcome, yet the underlying mechanisms are not fully understood. Since brain inflammation is an important modulator of neurological recovery after stroke, we explored the impact of PEM on neuroinflammation in the acute period in relation to stroke-initiated sensori-motor abnormalities. Adult rats were fed a low-protein (LP) or normal protein (NP) diet for 28  days before inducing photothrombotic stroke (St) in the forelimb region of the motor cortex or sham surgery; the diets continued for 3 days after the stroke. Prot...
Source: Translational Stroke Research - February 3, 2018 Category: Neurology Source Type: research

Wants Talk Psychotherapy but Cannot Talk: EMDR for Post-stroke Depression with Expressive Aphasia
CONCLUSION This is the first reported case demonstrating that EMDR can be effective for depression, even in those with severe expressive aphasia. In our case, there was no reluctance to disclose information, simply a neurological inability to do so. Through preparation, patience, perseverance, and plasticity (clinician flexibility, though perhaps also neuroplasticity), the patient’s PSD gradually improved, and she was able to reinvent her life within her limitations. ACKNOWLEDGMENTS The authors gratefully acknowledge Eugene Schwartz, E.C. Hurley, and Mark Hubner for providing consultation during patient care. REFERENCES ...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Neurologic Systems and Symptoms Neurology Psychotherapy Stroke aphasia depression EMDR Source Type: research

Medical News Today: This diet may slow cognitive decline after stroke
The risk of developing dementia doubles after having a stroke. Find out which diet can potentially stave off cognitive decline, according to new research.
Source: Health News from Medical News Today - January 26, 2018 Category: Consumer Health News Tags: Stroke Source Type: news

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease Brief Report
Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals of mortality were calcu...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano, Hiroyasu Iso, Akiko Tamakoshi Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Diet And Primary Prevention Of Stroke: Systematic Review And Dietary Recommendations By The Ad Hoc Working Group Of The Italian Society Of Human Nutrition
To systematically review the latest evidence on established and emerging nutrition-related risk factors for incidence of and mortality from total, ischemic and haemorrhagic strokes.The present review was conducted in the framework of the work carried out through 2015 and 2016 for the preparation of the Italian Guidelines for the Prevention and Treatment of Stroke, 8th Edition, by ISO-SPREAD (Italian Stroke Organization and the Stroke Prevention and Educational Awareness Diffusion).
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - January 15, 2018 Category: Nutrition Authors: Licia Iacoviello, Marialaura Bonaccio, Giulia Cairella, Maria Valeria Catani, Simona Costanzo, Rosalba Giacco, Domenico Rendina, Paola Sabino, Isabella Savini, Pasquale Strazzullo, Working Group for Nutrition and Stroke Tags: Systematic Reviews and Meta-analyses Source Type: research

Substitution of Linoleic Acid for Other Macronutrients and the Risk of Ischemic Stroke Clinical Sciences
Conclusions—This study suggests that replacing saturated fatty acid, glycemic carbohydrate, or monounsaturated fatty acid with linoleic acid may be associated with a lower risk of ischemic stroke.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Stine K. Veno, Erik B. Schmidt, Marianne U. Jakobsen, Soren Lundbye–Christensen, Flemming W. Bach, Kim Overvad Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Whole Grain Consumption and Risk of Ischemic Stroke Clinical Sciences
Conclusions—Although overall consumption of whole grains was not associated with lower risk of ischemic stroke, greater consumption of whole grain cold breakfast cereal and bran was significantly associated with a lower risk of ischemic stroke. More studies are needed to replicate these associations between individual whole grain foods and risk of ischemic stroke among other populations.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Juan Juan, Gang Liu, Walter C. Willett, Frank B. Hu, Kathryn M. Rexrode, Qi Sun Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Serum Potassium Is Positively Associated With Stroke and Mortality in the Large, Population-Based Malmo Preventive Proȷect Cohort Clinical Sciences
Background and Purpose—Low serum potassium is associated with stroke in populations with cardiovascular disease, hypertension, and diabetes mellitus but has not been studied in a mainly healthy population. We aimed to study the relation between serum potassium and incident stroke and mortality in the Malmö Preventive Project, a large cohort with screening in early mid-life and follow-up>25 years.Methods—Serum potassium measurements and covariates were available in 21 353 individuals (79% men, mean age 44 years). Mean follow-up time was 26.9 years for stroke analyses and 29.3 years for mortality analyses. There were ...
Source: Stroke - October 23, 2017 Category: Neurology Authors: Linda S. Johnson, Nick Mattsson, Ahmad Saȷadieh, Per Wollmer, Martin Soderholm Tags: Diet and Nutrition, Epidemiology, Lifestyle, Primary Prevention, Risk Factors Original Contributions Source Type: research

Dietary Sodium to Potassium Ratio and Risk of Stroke in a Multiethnic Urban Population Clinical Sciences
Conclusions—Na:K intake is an independent predictor of stroke risk. Further studies are required to understand the joint effect of Na and K intake on risk of cardiovascular disease.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Joshua Willey, Hannah Gardener, Sandino Cespedes, Ying K. Cheung, Ralph L. Sacco, Mitchell S.V. Elkind Tags: Diet and Nutrition, Epidemiology, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association AHA/ASA Presidential Advisory
Cognitive function is an important component of aging and predicts quality of life, functional independence, and risk of institutionalization. Advances in our understanding of the role of cardiovascular risks have shown them to be closely associated with cognitive impairment and dementia. Because many cardiovascular risks are modifiable, it may be possible to maintain brain health and to prevent dementia in later life. The purpose of this American Heart Association (AHA)/American Stroke Association presidential advisory is to provide an initial definition of optimal brain health in adults and guidance on how to maintain br...
Source: Stroke - September 25, 2017 Category: Neurology Authors: Philip B. Gorelick, Karen L. Furie, Costantino Iadecola, Eric E. Smith, Salina P. Waddy, Donald M. Lloyd-Jones, Hee-Joon Bae, Mary Ann Bauman, Martin Dichgans, Pamela W. Duncan, Meighan Girgus, Virginia J. Howard, Ronald M. Lazar, Sudha Seshadri, Fernando Tags: Statements and Guidelines AHA/ASA Presidential Advisory Source Type: research

Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke Clinical Sciences
Conclusions—High ECP is associated with increased incidence of IS. The association between ECP and IS was also present in the subgroup with carotid plaque.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Johannes Sundstrom, Martin Soderholm, Yan Borne, Jan Nilsson, Margaretha Persson, Gerd Ostling, Olle Melander, Marȷu Orho–Melander, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Dietary Approaches for Stroke Prevention Topical Review
Source: Stroke - September 25, 2017 Category: Neurology Authors: Susanna C. Larsson Tags: Diet and Nutrition, Risk Factors, Ischemic Stroke Topical Reviews Source Type: research

Response by Pase et al to Letter Regarding Article, “Sweetened Beverages and the Risks of Incident Stroke and Dementia” Letter to the Editor
Source: Stroke - August 28, 2017 Category: Neurology Authors: Matthew P. Pase, Jayandra J. Himali, Sudha Seshadri, Paul F. Jacques Tags: Diet and Nutrition, Epidemiology, Risk Factors, Ischemic Stroke Letters to the Editor Source Type: research

A Pilot Trial of a Lifestyle Intervention for Stroke Survivors: Design of Healthy Eating and Lifestyle after Stroke (HEALS)
Stroke survivors have high rates of subsequent cardiovascular and recurrent cerebrovascular events, and mortality. While healthy lifestyle practices - including a diet rich in fruits and vegetables, limited alcohol intake, and regular physical activity - can mitigate these outcomes, few stroke survivors adhere to them. Minorities from socioeconomically disadvantaged communities who obtain care in safety-net health systems experience the most barriers to implementing healthy lifestyle changes after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 16, 2017 Category: Neurology Authors: Valerie A. Hill, Barbara G. Vickrey, Eric M. Cheng, Natalie P. Valle, Monica Ayala-Rivera, Lilian Moreno, Cynthia Munoz, Heidi Dombish, Annaliese Espinosa, Debbie Wang, Dina Ochoa, Allison Chu, Rebecca Heymann, Amytis Towfighi Source Type: research

Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial
AbstractPost-stroke dysphagia is common, associated with poor outcome and often requires non-oral feeding/fluids. The relationship between route of feeding and outcome, as well as treatment with glyceryl trinitrate(GTN), was studied prospectively. The Efficacy of Nitric Oxide in Stroke (ENOS) trial assessed transdermal GTN (5  mg versus none for 7 days) in 4011 patients with acute stroke and high blood pressure. Feeding route (oral = normal or soft diet; non-oral = nasogastric tube, percutaneous endoscopic gastrostomy tube, parenteral fluids, no fluids) was assessed at baseline and day 7. The primary outcome was the mo d...
Source: Translational Stroke Research - August 2, 2017 Category: Neurology Source Type: research

Letter by Chiu Regarding Article, “Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia. A Prospective Cohort Study” Letter to the Editor
Source: Stroke - July 24, 2017 Category: Neurology Authors: Edward K. Chiu Tags: Diet and Nutrition, Ischemic Stroke Letters to the Editor Source Type: research

Dietary Protein Intake and Stroke Risk in a General Japanese Population Clinical Sciences
Background and Purpose—The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein.Methods—A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary protein intake was estimated using a 70-item semiquantitative food frequency questionnaire. The risk estimates for incident stroke and its subtypes were calculated using a Cox proportional hazards model.Results—During the follow-up, 254 participants experienced stroke events; of these, 172 had ischemic str...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Mio Ozawa, Daigo Yoshida, Jun Hata, Tomoyuki Ohara, Naoko Mukai, Mao Shibata, Kazuhiro Uchida, Masashi Nagata, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya Tags: Diet and Nutrition, Epidemiology, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Adherence to a Healthy Nordic Diet and Risk of Stroke Clinical Sciences
Conclusions—Our findings suggest that a healthy Nordic diet may be recommended for the prevention of stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Camilla Plambeck Hansen, Kim Overvad, Cecilie Kyro, Anȷa Olsen, Anne Tȷonneland, Soren Paaske Johnsen, Marianne Uhre Jakobsen, Christina Catherine Dahm Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Dietary Approaches to Stop Hypertension Diet and Incidence of Stroke: Results From 2 Prospective Cohorts Clinical Sciences
Conclusions— These findings indicate that high adherence to the DASH diet is associated with a reduced risk of ischemic stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifiers: NCT01127698 and NCT01127711 for the Swedish Mammography Cohort and the Cohort of Swedish Men, respectively.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Larsson, S. C., Wallin, A., Wolk, A. Tags: Diet and Nutrition, Epidemiology, Hypertension, Ischemic Stroke Clinical Sciences Source Type: research