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Total 827 results found since Jan 2013.

Does Adherence to Mediterranean Diet Mediate the Association Between Food Environment and Obesity Among Non-Hispanic Black and White Older US Adults? A Path Analysis.
CONCLUSION: Population-tailored interventions/policies to modify food environment and promote MD consumption are needed in order to combat the obesity crisis in the United States. PMID: 32048856 [PubMed - as supplied by publisher]
Source: American Journal of Health Promotion : AJHP - February 12, 2020 Category: International Medicine & Public Health Authors: Chen M, Howard V, Harrington KF, Creger T, Judd SE, Fontaine KR Tags: Am J Health Promot Source Type: research

High blood pressure: Sprinkling this seeds on your meals could lower your reading
HIGH blood pressure can increase your risk of having a heart attack or a stroke - but there's one simple diet change you should know about that can help you lower your reading.
Source: Daily Express - Health - February 9, 2020 Category: Consumer Health News Source Type: news

15-Year lipid profile effects on cardiovascular events adjusted for cardiovascular risk factors: a cohort study from Middle-East.
Conclusions: Dyslipidaemia, as an independent risk factor, was associated with future cardiovascular events. In this regard, serum lipid screening can help to decrease the risk of long-term cardiovascular events. PMID: 32019473 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - February 7, 2020 Category: Cardiology Tags: Acta Cardiol Source Type: research

Excess salt intake promotes M1 microglia polarization via a p38/MAPK/AR-dependent pathway after cerebral ischemia in mice.
In conclusion, HSD promotes polarization in pro-inflammatory M1 microglia by upregulating the expression of the AR protein via p38/MAPK, thereby exacerbating the development of ischemia stroke. PMID: 32044667 [PubMed - as supplied by publisher]
Source: International Immunopharmacology - February 7, 2020 Category: Allergy & Immunology Authors: Zhang T, Wang D, Li X, Jiang Y, Wang C, Zhang Y, Kong Q, Tian C, Dai Y, Zhao W, Jiang M, Chang Y, Wang G Tags: Int Immunopharmacol Source Type: research

Skipping breakfast before and during early pregnancy and incidence of gestational diabetes mellitus: the Japan Environment and Children's Study.
CONCLUSIONS: Breakfast consumption <3 times/wk before and during early pregnancy, compared with daily consumption, was associated with an increased odds of developing GDM. PMID: 32020171 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - February 5, 2020 Category: Nutrition Authors: Dong JY, Ikehara S, Kimura T, Cui M, Kawanishi Y, Kimura T, Ueda K, Iso H, Japan Environment and Children's Study Group Tags: Am J Clin Nutr Source Type: research

Dulaglutide: A Review in Type 2 Diabetes
AbstractSubcutaneous dulaglutide (Trulicity®) is a once-weekly glucagon-like peptide-1 receptor agonist that is approved in numerous countries as an adjunct to diet and exercise for the treatment of adults with type 2 diabetes (T2D). In the clinical trial and real-world settings, once-weekly subcutaneous dulaglutide, as monotherapy or add-on therapy to other antihyperglycaemic agents (including oral antihyperglycaemic drugs and insulin), was an effective and generally well tolerated treatment in adults with inadequately controlled T2D, including in high-risk patients [e.g. obese and elderly patients, those with stage 3 or...
Source: Drugs - January 30, 2020 Category: Drugs & Pharmacology Source Type: research

Dietary total antioxidant capacity and severity of stenosis in patients with coronary artery disease.
Conclusions: There was a significant association between dietary TAC and severity of stenosis in patients with coronary artery disease. PMID: 31984875 [PubMed - as supplied by publisher]
Source: International Journal for Vitamin and Nutrition Research - January 29, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, healthcare administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions. PMID: 31992061 [PubMed - as supplied by publisher]
Source: Circulation - January 29, 2020 Category: Cardiology Authors: Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longeneck Tags: Circulation Source Type: research

Trends in nutritional intake and coronary risk factors over 60  years among Japanese men in Tanushimaru
AbstractWe investigated the relationship between time trends in nutrient intake and coronary risk factors/mortality rates in Tanushimaru, a Japanese cohort of the Seven Countries Study. All men between the ages of 40 and 64 were enrolled. Subjects numbered 628 in 1958, 539 in 1977, 602 in 1982, 752 in 1989, 402 in 1999, 329 in 2009, and 160 in 2018. Eating patterns were evaluated by 24-h dietary recall from 1958 through 1989, and by a food frequency questionnaire administered from 1999 through 2018. The total daily energy intake decreased from 2,837  kcal in 1958 to 2,096 kcal in 2018. Carbohydrate intake as a percentage...
Source: Heart and Vessels - January 29, 2020 Category: Cardiology Source Type: research

Use of a bioengineered antioxidant in mouse models of metabolic syndrome.
Conclusions: PEG-HCC can improve some parameters of disease in these models and this may be due to a resulting increase in peripheral insulin sensitivity. However, additional studies are needed to elucidate how PEG-HCCs are producing these effects. PMID: 31937152 [PubMed - as supplied by publisher]
Source: Expert Opinion on Investigational Drugs - January 17, 2020 Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research

Advancing mediation analysis in occupational health research
In recent years, mediation analysis has become a popular means to identify and quantify pathways linking an exposure to an outcome, thereby elucidating how a particular exposure contributes to the occurrence of a specific outcome. When a mediator is a modifiable risk factor, this opens up new opportunities for interventions to block (part) of the exposure`s effect on the outcome. Recent examples in Scandinavian Journal of Work Environment Health have addressed the mediating effect of wellbeing on the association between type of office and job satisfaction (1) and examined whether workplace social capital contributes to the...
Source: Scandinavian Journal of Work, Environment and Health - January 17, 2020 Category: Occupational Health Tags: Editorial Source Type: research

Carbohydrate Quality, Glycemic Index, Glycemic Load and Cardiometabolic Risks in the US, Europe and Asia: A Dose-Response Meta-Analysis
ConclusionsOverweight/obese females can shift their carbohydrate intake for higher cereal fiber to decrease T2DM risk, but GL may cancel-out this effect.
Source: Nutrition, Metabolism and Cardiovascular Diseases - January 15, 2020 Category: Nutrition Source Type: research

Cardiovascular health of nonagenarians in southern Italy: a cross-sectional, home-based pilot study of longevity
Conclusion Nonagenarians and centenarians in the Cilento region had a healthy metabolic profile and a low prevalence of clinical cardiovascular disease. Even among nonagenarians and centenarians with structural heart abnormalities, report of symptoms is low. Larger studies in the Cilento population may help elucidate the mechanisms underlying cardiovascular health in the oldest old.
Source: Journal of Cardiovascular Medicine - January 14, 2020 Category: Cardiology Tags: Research articles: Epidemiology Source Type: research

IJERPH, Vol. 17, Pages 513: Exploring the Relationship between Green Space in a Neighbourhood and Cardiovascular Health in the Winter City of China: A Study Using a Health Survey for Harbin
iuli An A severely cold climate has a significant impact on cardiovascular health, involving temperature, air environment, exercise and diet. Existing studies have revealed that green space, as an important health resource, may play a positive role in promoting cardiovascular health through the air environment and exercise. Studies focusing on the correlation between green space and cardiovascular health are rarely carried out in winter cities. The purpose of this paper is to take a winter city in China as an empirical case to explore the correlation between green space in a neighbourhood and cardiovascular health in a...
Source: International Journal of Environmental Research and Public Health - January 14, 2020 Category: Environmental Health Authors: Hong Leng Shuyuan Li Shichun Yan Xiuli An Tags: Article Source Type: research

Eat better, for your heart's sake: Consuming more fruits and vegetables reduces risk of death from heart attack, stroke say researchers
(Natural News) The American Heart Association lists heart disease as one of the leading causes of death in the US. This statistic emphasizes the need to find ways to prevent the onset of this deadly disease. Making healthy lifestyle choices, including proper dietary choices, is one of the best ways to keep your heart and...
Source: NaturalNews.com - January 13, 2020 Category: Consumer Health News Source Type: news

Carbohydrate Quality, Glycemic Index, Glycemic Load and Cardiometabolic Risks in the US, Europe and Asia: A Dose-Response Meta-Analysis
Despite the proven evidence of high glycemic index (GI) and glycemic load (GL) diets to increase cardiometabolic risks, knowledge about the meta-evidence for carbohydrate quality within world geographic regions is limited. We conducted a meta-analysis to synthesize the evidence of GI/GL studies and carbohydrate quality, gathering additional exposures for carbohydrate, high glycemic carbohydrate, total dietary fiber, and cereal fiber and risks for type 2 diabetes (T2DM), coronary heart disease (CHD), stroke, and mortality, grouped into the US, Europe, and Asia.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - January 13, 2020 Category: Nutrition Authors: D.S. Hardy, J.T. Garvin, H. Xu Tags: Systematic Reviews and Meta-analyses Source Type: research

Characteristics of Cerebral Stroke in the Tibet Autonomous Region of China.
This article focuses on epidemiology features, risk factors, and pathogenesis of stroke in the TAR in an effort to generate a better understanding of the characteristics of stroke in this region. The special plateau-related factors such as its high elevation, limited oxygen, the high incidence of hypertension, smoking, and the unique dietary habits of the region are correlated with the high incidence of stroke. In addition to these factors, the pathogenesis of stroke in this high-altitude area is also unique. However, there is no established explanation for the unique occurrence and high incidence of stroke in the TAR. Our...
Source: Medical Science Monitor - January 11, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Diet quality as a predictor of cardiometabolic disease-free life expectancy: the Whitehall II cohort study.
CONCLUSIONS: Healthier dietary habits are associated with cardiometabolic disease-free life expectancy between ages 50 and 85. PMID: 31927573 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - January 11, 2020 Category: Nutrition Authors: Lagström H, Stenholm S, Akbaraly T, Pentti J, Vahtera J, Kivimäki M, Head J Tags: Am J Clin Nutr Source Type: research

Study: Drinking Tea May Help You Live Longer, Especially If It ’ s Green
This study strengthens the body of evidence that habitual tea drinking is associated with lower rates of atherosclerotic cardiovascular disease, though it cannot prove that it’s definitely the tea that’s responsible,” Dr. Jenna Macciochi, a lecturer in immunology at the University of Sussex, told the SMC. However, she noted that “a body of evidence in nutrition suggests that whole diet patterns are more informative of diet-disease relationships than any isolated food or nutrient.” Dr. Duane Mellor, a registered dietitian and senior teaching fellow at Aston Medical School, Aston University, sai...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Green Tea Source Type: news

Reducing Tongue Fat Could Improve Sleep Apnea, Study Says
This study shows reducing excess fat in general can reduce tongue size,” said Dr. Raj Dasgupta, a sleep specialist at Keck Medicine at the University of Southern California, who was not involved in the study. In the new paper, the researchers used MRI imaging to measure the effect on upper airways of a 10% weight loss in 67 obese patients. The images showed reducing tongue fat was the primary reason overall sleep apnea scores improved by 31%. “In fact, the more tongue fat you lost, the more your apnea improved,” said Schwab, who is the co-director of the Penn Sleep Center at Penn Medicine. Costs of sleep ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated CBSN Boston CNN Source Type: news

Critical Differences Between Dietary Supplement and Prescription Omega-3 Fatty Acids: A Narrative Review
ConclusionConsumers and health care providers need to recognize critical differences between Rx and OM-3 dietary supplements to ensure appropriate use of each OM-3 product.
Source: Advances in Therapy - January 9, 2020 Category: Drugs & Pharmacology Source Type: research

Associations of choline-related nutrients with cardiometabolic and all-cause mortality: results from 3 prospective cohort studies of blacks, whites, and Chinese.
CONCLUSIONS: High choline intake was associated with increased cardiometabolic mortality in racially diverse populations. PMID: 31915809 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - January 8, 2020 Category: Nutrition Authors: Yang JJ, Lipworth LP, Shu XO, Blot WJ, Xiang YB, Steinwandel MD, Li H, Gao YT, Zheng W, Yu D Tags: Am J Clin Nutr Source Type: research

Psychosocial and behavioral characteristics of still smokers at 6 months after acute cerebro or cardiovascular events: Findings from INEV@L, a prospective pilot study
ConclusionOur pilot study in young workers highlights the low rate of smoking cessation, and generalized dual use of electronic + conventional cigarette at mid-term after acute MI or stroke. Our findings further suggest specific PSF pattern of non-quitters, associated with loss of perceived disease severity.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research

Gen X Women Get Less Sleep Than Any Other Generation. What ’s Keeping Them Up?
In the middle of the night, I wake up feeling warm. I open the window and pull my hair back into a ponytail and drink some water. Then I glance at my phone, delete a few things, and see some spam. I hit unsubscribe and go back to bed. Then I lie there thinking, What if by opening that spam email I got myself hacked? What if I just sent everyone in my contact list a Burger King ad at two in the morning? Now wide awake, I move on to other concerns: my parents’ health, my stepson’s college tuition, pending deadlines. Hours roll by. I tackle real-life math problems: how many weeks I have before getting my next free...
Source: TIME: Health - January 6, 2020 Category: Consumer Health News Authors: Ada Calhoun Tags: Uncategorized Gen X healthy sleep insomnia Source Type: news

Mfsd2a Attenuates Blood-Brain Barrier Disruption After Sub-arachnoid Hemorrhage by Inhibiting Caveolae-Mediated Transcellular Transport in Rats
In this study, a prechiasmatic cistern single-injection model was used to produce experimental SAH in Sprague-Dawley rats. Specific small-interfering RNA and plasmids were used to downregulate and upregulate the expression of Mfsd2a prior to assessments in our SAH model. Omega-3 fatty acid deficiency diet was used to reduce DHA in rat brain. The expression level of Mfsd2a decreased significantly after SAH and reached its lowest level at 72  h post-SAH, which then gradually recovered. At 72 h after SAH, BBB function was disrupted; upregulation of Mfsd2a reversed this damage, whereas downregulation of Mfsd2a exacerbated th...
Source: Translational Stroke Research - January 6, 2020 Category: Neurology Source Type: research

Exposure to dietary polychlorinated biphenyls and dioxins, and its relationship with subclinical coronary atherosclerosis: The Aragon Workers' Health Study.
CONCLUSIONS: In this general male population, dietary exposure to PCBs, but not to dioxins, was associated with a higher prevalence of coronary calcium and to more intense subclinical coronary atherosclerosis. PCBs exposure seems to increase the risk of coronary disease in men from the very early stages. PMID: 31918334 [PubMed - as supplied by publisher]
Source: Environment International - January 6, 2020 Category: Environmental Health Authors: Donat-Vargas C, Moreno-Franco B, Laclaustra M, Sandoval-Insausti H, Jarauta E, Guallar-Castillon P Tags: Environ Int Source Type: research

Five Ways To Improve Your Mental Health In 2020
(CNN) — It’s a difficult birth for this new decade. The year 2020 kicks off under the shadow of divisive politics, international security threats, a spate of hate crimes, and a planet in environmental peril, plus all the reasons we’re stressed individually: work, health problems, life changes and more. No wonder so many of us are anxious or depressed. But you can take scientifically validated steps to improve your mental outlook, and — because the mind and body are entwined — these behaviors also will improve your overall health. 1. Practice optimism The studies are positive: Looking on the br...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 4, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Mental Health Source Type: news

Vitamin D, Marine n-3 Fatty Acids, and Primary Prevention of Cardiovascular Disease Current Evidence.
Abstract Whether marine omega-3 fatty acid (n-3 FA) or vitamin D supplementation can prevent cardiovascular disease (CVD) in general populations at usual risk for this outcome is unknown. A major goal of VITAL (Vitamin D and Omega-3 Trial) was to fill this knowledge gap. In this article, we review the results of VITAL, discuss relevant mechanistic studies regarding n-3 FAs, vitamin D, and vascular disease, and summarize recent meta-analyses of the randomized trial evidence on these agents. VITAL was a nationwide, randomized, placebo-controlled, 2×2 factorial trial of marine n-3 FAs (1 g/d) and vitamin D3 (2000 IU...
Source: Circulation Research - January 3, 2020 Category: Cardiology Authors: Manson JE, Bassuk SS, Cook NR, Lee IM, Mora S, Albert CM, Buring JE, VITAL Research Group Tags: Circ Res Source Type: research

The prevalence of stroke according to indoor radon concentration in South Koreans: Nationwide cross section study
This study combines 2 nationwide studies. Demographic characteristics and medical history of participants were obtained from Korean National Health and Nutrition Examination Survey (KNHANES) from 2007 to 2012. Participants over 40 years old and who completed the questionnaire were included in the study. Indoor radon concentration was analyzed using the mean value of winter housing radon concentration from 2012 to 2016 published by the National Institute of Environmental Research. The average values of each metropolitan city and province were assigned to the residence of the participant. To eliminate the potential confoundi...
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Suboptimal Diet May Drive $50 Billion in Cardiometabolic Costs Suboptimal Diet May Drive $50 Billion in Cardiometabolic Costs
Poor diet is associated with 18.2% of all costs related to treatment of ischemic heart disease, stroke, and type 2 diabetes in the US, new research estimates.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - December 31, 2019 Category: Primary Care Tags: Cardiology News Source Type: news

Inhibition of Endothelial Dysfunction by Dietary Flavonoids and Preventive Effects Against Cardiovascular Disease
Abstract: Cardiovascular disease (CVD), such as stroke, ischemic heart disease, and heart failure, accounts for many deaths, and its increasing incidence is a worldwide concern. Accumulating evidence suggests that the elevated risk of CVD caused by dysfunction of vascular endothelial cells and resultant arteriosclerosis can be mitigated by increased consumption of fruits and vegetables. These foods contain phytochemicals such as polyphenols and carotenoids, as well as dietary fiber. Flavonoids of the polyphenol class are found in vegetables, fruits, grains, bark, roots, stems, flowers, tea, and wine. Several studies have...
Source: Journal of Cardiovascular Pharmacology - December 31, 2019 Category: Cardiology Tags: Review Article Source Type: research

Impact of increased venous pressure on kidney function and mortality in cardiovascular patients with preserved ejection fraction.
Conclusions: Our study demonstrates that right ventricular preload affects renal function in patients with preserved systolic function and that neither aortic systolic pressure nor left ventricle pressure indices were related to estimated glomerular filtration rate. Furthermore, we demonstrated for the first time that an increased RAP is able to predict a worse prognosis in patients with preserved ejection fraction independently of well-established risk factors, such as blood pressure and SVI. PMID: 31868029 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - December 25, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research

Unhealthy Eating Habits Cost U.S. $50 Billion a Year: Study
THURSDAY, Dec. 19, 2019 -- Healthier eating could save the United States more than $50 billion a year in health care costs associated with heart disease, stroke, type 2 diabetes and related illnesses, according to a new study. An unhealthy diet is...
Source: Drugs.com - Daily MedNews - December 19, 2019 Category: General Medicine Source Type: news

Eating Chili Peppers Cuts Risk Of Death From Heart Attack And Stroke, Study Says
(CNN) — That delicious penne all’arrabiata may have benefits that go further than putting a smile on your face, according to a new study. For many years, chili has been hailed for its therapeutic properties, and now researchers have found that eating chili peppers regularly can cut the risk of death from heart disease and stroke. Carried out in Italy, where chili is a common ingredient, the study compared the risk of death among 23,000 people, some of whom ate chili and some of whom didn’t. Participants’ health status and eating habits were monitored over eight years, and researchers found that the ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 17, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Source Type: news

Cardiometabolic disease costs associated with suboptimal diet in the United States: A cost analysis based on a microsimulation model
ConclusionsSuboptimal diet of 10 dietary factors accounts for 18.2% of all ischemic heart disease, stroke, and type 2 diabetes costs in the US, highlighting that timely implementation of diet policies could address these health and economic burdens.
Source: PLoS Medicine - December 17, 2019 Category: Internal Medicine Authors: Thiago Veiga Jardim Source Type: research

Cardiac hypertrophy with obesity is augmented after pregnancy in C57BL/6 mice
ConclusionsThese results suggest that the combined effects of pregnancy and obesity augment cardiac hypertrophy and promote remodeling. The rising prevalence of CVD in premenopausal women may be attributed to an increased prevalence of women entering pregnancy with an overweight or obese BMI.
Source: Biology of Sex Differences - December 16, 2019 Category: Biology Source Type: research

Dietary Cholesterol and Cardiovascular Risk: A Science Advisory From the American Heart Association.
sis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Peripheral Vascular Disease; and Stroke Council Abstract The elimination of specific dietary cholesterol target recommendations in recent guidelines has raised questions about its role with respect to cardiovascular disease. This advisory was developed after a review of human studies on the relationship of dietary cholesterol with blood lipids, lipoproteins, and cardiovascular disease risk to address questions about the relevance of dietary cholesterol guidance for heart health. Evidence from observat...
Source: Circulation - December 16, 2019 Category: Cardiology Authors: Carson JAS, Lichtenstein AH, Anderson CAM, Appel LJ, Kris-Etherton PM, Meyer KA, Petersen K, Polonsky T, Van Horn L, American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Arteriosclerosis, Thromb Tags: Circulation Source Type: research

Metabolic syndrome and risks of carotid atherosclerosis and cardiovascular events in community-based older adults in China.
CONCLUSIONS: MS was significantly associated with IMT and the presence of carotid plaque and with positively increased risks of MI, stroke, and CVD mortality independent of CVD risk factors in older Chinese adults. PMID: 31826385 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - December 12, 2019 Category: Nutrition Authors: Wang C, Fang X, Wu X, Hua Y, Zhang Z, Gu X, Tang Z, Guan S, Liu H, Liu B, Ji X Tags: Asia Pac J Clin Nutr Source Type: research

Top 10 Health Questions America Asked Dr. Google In 2019
(CNN) — Google users in the United States had a lot of questions about blood pressure, the keto diet and hiccups in 2019. Those topics were among the 10 most-searched health-related questions on the search engine this year, according to new data from Google. The list was based on search terms collected between January and early December. Last year, the top health-related questions Googled by people in the US included what is amyotrophic lateral sclerosis, or ALS, what is endometriosis and how long does weed stay in your urine. In 2017, what is lupus, how long does the flu last and what causes hiccups were some of the...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 12, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Google Source Type: news

Low-Dose Aspirin May Not Reduce Heart Risks for Black Americans, Study Finds
It’s fairly established medical science that people who have had heart attacks can take regular low doses of aspirin to significantly lower their risk of having another heart attack, or other heart problems including stroke. But it is still an open question whether or not people who haven’t had a heart event, but are at higher risk of one (because, for example) they have diabetes, high blood pressure, or elevated cholesterol levels), can also benefit from the over-the-counter painkiller and anti-inflammatory drug. A new study, published in the Journal of the American Heart Association, adds to that debate by ad...
Source: TIME: Health - December 11, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized aspirin Drugs Heart Disease Source Type: news

IJERPH, Vol. 16, Pages 4957: Does Nut Consumption Reduce Mortality and/or Risk of Cardiometabolic Disease? An Updated Review Based on Meta-Analyses
Conclusion. Nut consumption appears to exert a protective effect on cardiometabolic disease, possibly through improved concentrations of fasting glucose, total cholesterol, and LDL-C.
Source: International Journal of Environmental Research and Public Health - December 6, 2019 Category: Environmental Health Authors: Yoona Kim Jennifer B Keogh Peter M Clifton Tags: Review Source Type: research

Why You Should Start Thinking About Your Cholesterol Earlier
High cholesterol is known to be one of the primary risk factors for heart disease, since it can contribute to plaque buildup in the arteries. But even though the U.S. Centers for Disease Control and Prevention recommends regular cholesterol testing starting around age 20, many Americans don’t give cholesterol—or heart disease, for that matter—much thought until later in life. A new modeling study published in the Lancet gives extra reason not to put off cholesterol screening and treatment. It confirms that high blood levels of “bad” (or non-HDL) cholesterol are associated with a greater risk o...
Source: TIME: Health - December 4, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Research Source Type: news

AHA News: Vegan Diet May Decrease Heart Disease, Stroke Risk in African Americans
TUESDAY, Dec. 3, 2019 (American Heart Association News) -- Following a vegan diet for five weeks may decrease risk factors for heart disease, new research shows. The study included 50 African Americans who were asked to eat only prepared meals...
Source: Drugs.com - Daily MedNews - December 3, 2019 Category: General Medicine Source Type: news

Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization
AbstractA disabling consequence of stroke is cognitive impairment, occurring in 12% –48% of patients, for which there is no therapy. A critical barrier is the lack of understanding of how post-stroke cognitive impairment (PSCI) develops. While 70% of stroke victims present with comorbid diseases such as diabetes and hypertension, the limited use of comorbid disease models in prec linical research further contributes to this lack of progress. To this end, we used a translational model of diabetes to study the development of PSCI. In addition, we evaluated the application of compound 21 (C21), an angiotensin II Type 2 rece...
Source: Translational Stroke Research - December 3, 2019 Category: Neurology Source Type: research

Imbalance in the force: the dark side of the microbiota on stroke risk and progression.
Abstract The composition of the gut microbiota depends on many factors, including our lifestyle, diet, metabolism, antibiotic use and hygiene. The contribution of these factors in shaping the gut microbiota and the subsequent effects on the prevention and development of stroke has been under intense investigation. Furthermore, several reports have uncovered the impact of stroke on intestinal dysfunction and gut dysbiosis, highlighting the delicate interplay between the brain, gut and microbiome following this acute brain injury. Despite our growing appreciation of the gut microbiota in shaping brain health, the im...
Source: Current Opinion in Neurobiology - December 3, 2019 Category: Neurology Authors: Prame Kumar K, Wong CH Tags: Curr Opin Neurobiol Source Type: research

Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus.
CONCLUSIONS: Metformin compared with placebo or diet and exercise reduced or delayed the risk of T2DM in people at increased risk for the development of T2DM (moderate-quality evidence). However, metformin compared to intensive diet and exercise did not reduce or delay the risk of T2DM (moderate-quality evidence). Likewise, the combination of metformin and intensive diet and exercise compared to intensive diet and exercise only neither showed an advantage or disadvantage regarding the development of T2DM (very low-quality evidence). Data on patient-important outcomes such as mortality, macrovascular and microvascular diabe...
Source: Cochrane Database of Systematic Reviews - December 3, 2019 Category: General Medicine Authors: Madsen KS, Chi Y, Metzendorf MI, Richter B, Hemmingsen B Tags: Cochrane Database Syst Rev Source Type: research

Dietary saturated fat intake and risk of stroke: Systematic review and dose–response meta-analysis of prospective cohort studies
ConclusionThis meta-analysis further demonstrated that a higher consumption of dietary SFA is associated with a lower risk of stroke, and every 10 g/day increase in SFA intake is associated with a 6% relative risk reduction in the rate of stroke. Further research is needed to explore the influence of specific SFA types and different macronutrient replacement models of SFA on the stroke risk.
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 30, 2019 Category: Nutrition Source Type: research

Potassium binding for conservative and preservative management of chronic kidney disease
In conclusion, there are new well tolerated and effective K+-binding agents for acutely and chronically managing hyperkalemia.
Source: Current Opinion in Nephrology and Hypertension - November 29, 2019 Category: Urology & Nephrology Tags: NOVEL THERAPEUTIC APPROACHES IN NEPHROLOGY AND HYPERTENSION: Edited by Kamyar Kalantar-Zadeh and Ekamol Tantisattamo Source Type: research

Long-Term Trajectories of Body Weight, Diet, and Physical Activity From Midlife Through Late-Life and Subsequent Cognitive Decline in Women.
In conclusion, maintaining healthy lifestyle since midlife may help reduce cognitive decline in aging. At older ages, both deceleration of weight gain and decrease in physical activity may reflect early signs of cognitive impairment. PMID: 31781745 [PubMed - as supplied by publisher]
Source: Am J Epidemiol - November 29, 2019 Category: Epidemiology Authors: Wagner M, Grodstein F, Proust-Lima C, Samieri C Tags: Am J Epidemiol Source Type: research

This Under-Utilized Drug Is Actually Critical for Treatment-Resistant Depression
Many people with clinical depression have tried an array of medication and still feel sick. Maybe they’ve tried different selective serotonin reuptake inhibitors (SSRIs) or selective norepinephrine reuptake inhibitors (SNRIs). Maybe they’ve taken these antidepressants along with an antipsychotic (a common strategy to boost effectiveness). Either way, the lack of improvement can make individuals feel even more hopeless and fear the darkness will never lift. If this sounds all-too familiar, you’re definitely not alone. In fact, up to 30 percent of people with depression don’t respond to the first few antidepressants ...
Source: Psych Central - November 27, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Antidepressants Depression Disorders ECT General Medications Treatment Atypical Depression difficult to treat depression Managing Depression MAOIs medication for depression Monoamine Oxidase Inhibitors Severe Depression Treatin Source Type: news