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Total 210 results found since Jan 2013.

Epigenetics of Early-Life Socioeconomic Stressors and the Impact on Childhood Body Mass Index —Potential Mechanism and Biomarker?
Overweight and obesity are growing epidemics worldwide. Recent estimates from the World Health Organization indicate that 39% of adults had overweight, and 13% had obesity. In addition, an estimated 340 million children and adolescents aged 5 to 19 years had overweight or obesity in 2016 whereas 39 million children younger than 5 years had overweight or obesity in 2020. Understanding the biological mechanisms behind the development of overweight and obesity is critical as overweight and obesity are risk factors for a host of cardiometabolic outcomes including heart disease, stroke, diabetes, and chronic kidney disease. The...
Source: JAMA Pediatrics - September 5, 2023 Category: Pediatrics Source Type: research

Use of hospital services by patients with chronic conditions in sub-Saharan Africa: a systematic review and meta-analysis
CONCLUSION: Among patients seeking hospital care in sub-Saharan Africa, multimorbidity remains poorly described despite high burdens of individual chronic diseases. Prospective public health studies of multimorbidity burden are needed to generate integrated and context-specific health system interventions that act to maximize patient survival and well-being.PMID:37638357 | PMC:PMC10452942 | DOI:10.2471/BLT.22.289597
Source: Bulletin of the World Health Organization - August 28, 2023 Category: International Medicine & Public Health Authors: Stephen A Spencer Jamie Rylance Jennifer K Quint Stephen B Gordon Paul Dark Ben Morton Source Type: research

News at a glance: A win for obesity drugs, NIH unionization roadblocks, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: ScienceNOW - August 10, 2023 Category: Science Source Type: news

News at a glance: A win for obesity drugs, a new infectious disease institute head, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: Science of Aging Knowledge Environment - August 10, 2023 Category: Geriatrics Source Type: research

Statement on Tobacco 21 from the European Respiratory Society Tobacco Control Committee
Tobacco consumption is the most significant cause of premature death across the European Union (EU) and is responsible for 700 000 deaths every year. Smokers are more likely than nonsmokers to develop lung cancer, COPD, coronary artery disease, stroke, diabetes, infertility and many other conditions [1]. According to Eurostat, 18.4% of people aged 15 years and over in the EU were daily smokers in 2019 [2]. Across Europe, the minimum age of sale of tobacco products is 18 years as per the obligations of the World Health Organization's Framework Convention on Tobacco Control (WHO FCTC).
Source: European Respiratory Journal - March 23, 2023 Category: Respiratory Medicine Authors: Cox, D. W., Rodriguez, L., Grigg, J., on behalf of the Tobacco Control Committee of the European Respiratory Society Tags: Editorials Source Type: research

Nanocarriers and Diabetes: New Vistas and the way ahead
Curr Pharm Biotechnol. 2022 Dec 27. doi: 10.2174/1389201024666221227140728. Online ahead of print.ABSTRACTWorld Health Organization has reported an estimated 1.5 million deaths directly due to diabetes in 2019. Center for Disease Control and Prevention, in its National Diabetes Statistics Report, 2020, says that 1 in 10 United States residents has diabetes. This rapid progression of diabetes is noteworthy despite significant advances in the field of antidiabetic medicine. The critical challenges in treatment are dyslipidemia, hyperinsulinemia, and hyperglycemia. The latest research has also linked diabetes to carcinogenesi...
Source: Current Pharmaceutical Biotechnology - December 29, 2022 Category: Biotechnology Authors: Pankaj V Dixit Dinesh K Mishra Sanjay Sharma Rupesh K Gautam Source Type: research

Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research