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Total 119 results found since Jan 2013.

Sensors, Vol. 23, Pages 6150: A Rigorous and Integrated On-Water Monitoring System for Performance and Technique Improvement in Rowing
oulis This paper presents a prototype, on-water rowing monitoring system and its testing results for a single scull boat. The proposed system aims at recording critical kinetic (athlete biomechanics and oar/seat movements) and kinematic (boat position, velocity, acceleration, and attitude) parameters for sport performance evaluation and rowing technique improvement. The data acquisition unit is organized in two parts: the first part aims at logging boat kinematics based on GNSS/INS filtering, while the second one facilitates kinetics data recording using a series of analog sensors (potentiometers, strain gauges) instal...
Source: Sensors - July 4, 2023 Category: Biotechnology Authors: Thanassis Mpimis Vassilis Gikas Vassilios Gourgoulis Tags: Article Source Type: research

Case report: Flow changes in routes of collateral circulation in patients with LVO and low NIHSS: a point favor to treat
In this study, we present the case of a 62-year-old individual, with left internal carotid occlusion stroke and low NIHSS, who had compensatory collateral flow from Willis polygon via the anterior communicating artery. The patient subsequently exhibited neurological deterioration and collateral flow failure from Willis polygon, indicating the need for urgent intervention. The study of collaterals in patients with large vessel occlusion stroke has garnered considerable attention, with research suggesting that individuals with low NIHSS scores and poor collateral profiles may be at a heightened risk of early neurological det...
Source: Frontiers in Neurology - June 8, 2023 Category: Neurology Source Type: research

Clonal Hematopoiesis in Myeloproliferative Neoplasms Confers a Predisposition to both Thrombosis and Cancer
AbstractPurpose of ReviewThis review focuses on vascular complications associated with chronic myeloproliferative neoplasms (MPN) and more specifically aims to discuss the clinical and biological evidence supporting the existence of a link between clonal hematopoiesis, cardiovascular events (CVE), and solid cancer (SC).Recent FindingsThe MPN natural history is driven by uncontrolled clonal myeloproliferation sustained by acquired somatic mutations in driver (JAK2, CALR, and MPL) and non-driver genes, involving epigenetic (e.g., TET2, DNMT3A) regulators, chromatin regulator genes (e.g., ASXL1, EZH2), and splicing machinery ...
Source: Current Hematologic Malignancy Reports - May 24, 2023 Category: Hematology Source Type: research

An Update on the Treatment of Basilar Artery Occlusion
AbstractPurpose of ReviewBasilar artery occlusion (BAO) is one of the most devastating forms of ischemic stroke with historically high mortality and disability rates. Here, we evaluate the current interventions available to clinicians and present the most recent evidence from randomized clinical trials in support of endovascular thrombectomy as the treatment of choice for BAO.Recent FindingsTwo recent randomized clinical trials (ATTENTION and BAOCHE) have provided convincing evidence of the superiority of endovascular thrombectomy over medical management for patients with BAO. Although questions regarding the generalizabil...
Source: Current Treatment Options in Neurology - March 3, 2023 Category: Neurology Source Type: research

Current Evaluation of Intracerebral Hemorrhage
Advanced imaging is currently critical in diagnosing, predicting, and managing intracerebral hemorrhage. MD CT angiography has occupied the first line of evaluating patients with a clinical diagnosis of a stroke, given its rapid acquisition time, high resolution of vascular structures, and sensitivity for secondary causes of ICH.
Source: Radiologic Clinics of North America - February 20, 2023 Category: Radiology Authors: Javier M. Romero, Luisa F. Rojas-Serrano Source Type: research

Rapid MRI protocol leads to reduced image acquisition times
A rapid lumbar MRI protocol that uses 3D imaging and deep learning reconstructio...Read more on AuntMinnie.comRelated Reading: Reducing use of sedation for pediatric MRI cuts healthcare costs Ultrafast MRI shows promise in predicting DCIS upstaging Ultrafast DCE-MRI helps predict breast cancer treatment response Is abbreviated MRI useful for women at average breast cancer risk? Rapid MRI for ED stroke evaluation cuts costs, hospital length of stay
Source: AuntMinnie.com Headlines - January 6, 2023 Category: Radiology Source Type: news

Optogenetic Stimulation Array for Confocal Microscopy Fast Transient Monitoring
Optogenetics is an emerging discipline with multiple applications in neuroscience, allowing to study neuronal pathways or serving for therapeutic applications such as in the treatment of anxiety disorder, autism spectrum disorders (ASDs), or Parkinson's disease. More recently optogenetics is opening its way also to stem cell-based therapeutic applications for neuronal regeneration after stroke or spinal cord injury. The results of optogenetic stimulation are usually evaluated by immunofluorescence or flow cytometry, and the observation of transient responses after stimulation, as in cardiac electrophysiology studies...
Source: IEEE Transactions on Biomedical Circuits and Systems - December 1, 2022 Category: Biomedical Engineering Source Type: research

Sensors, Vol. 22, Pages 8519: Evaluation of Unobtrusive Microwave Sensors in Healthcare 4.0 & mdash;Toward the Creation of Digital-Twin Model
Sensors, Vol. 22, Pages 8519: Evaluation of Unobtrusive Microwave Sensors in Healthcare 4.0—Toward the Creation of Digital-Twin Model Sensors doi: 10.3390/s22218519 Authors: Sagheer Khan Imran M. Saied Tharmalingam Ratnarajah Tughrul Arslan The prevalence of chronic diseases and the rapid rise in the aging population are some of the major challenges in our society. The utilization of the latest and unique technologies to provide fast, accurate, and economical ways to collect and process data is inevitable. Industry 4.0 (I4.0) is a trend toward automation and data exchange. The utilization of the sam...
Source: Sensors - November 5, 2022 Category: Biotechnology Authors: Sagheer Khan Imran M. Saied Tharmalingam Ratnarajah Tughrul Arslan Tags: Article Source Type: research

Brain PET and Cerebrovascular Disease
Cerebrovascular disease encompasses a broad spectrum of diseases such as stroke, hemorrhage, and cognitive decline associated with vascular narrowing, obstruction, rupture, and inflammation, among other issues. Recent advances in hardware and software have led to improvements in brain PET. Although still in its infancy, machine learning using convolutional neural networks is gaining traction in this area, often with a focus on providing high-quality images with reduced noise using a shorter acquisition time or less radiation exposure for the patient.
Source: PET Clinics - October 27, 2022 Category: Radiology Authors: Katarina Chiam, Louis Lee, Phillip H. Kuo, Vincent C. Gaudet, Sandra E. Black, Katherine A. Zukotynski Source Type: research

MRI-Visible Anatomy of the Brainstem
Human brainstem internal anatomy is intricate, complex, and essential to normal brain function. The brainstem is affected by stroke, multiple sclerosis, and most neurodegenerative diseases —a 1-mm focus of pathologic condition can have profound clinical consequences. Unfortunately, detailed internal brainstem anatomy is difficult to see with conventional MRI sequences. We review normal brainstem anatomy visualized on widely available clinical 3-T MRI scanners using fast gray matter acquisition T1 inversion recovery, probabilistic diffusion tractography, neuromelanin, and susceptibility-weighted imaging. Better anatomic l...
Source: Neuroimaging Clinics - July 15, 2022 Category: Radiology Authors: Timothy M. Shepherd, Michael J. Hoch Source Type: research

An Inexpensive Open-Source Chamber for Controlled Hypoxia/Hyperoxia Exposure
Understanding hypoxia/hyperoxia exposure requires either a high-altitude research facility or a chamber in which gas concentrations are precisely and reproducibly controlled. Hypoxia-induced conditions such as hypoxic-ischemic encephalopathy (HIE), obstructive or central apneas, and ischemic stroke present unique challenges for the development of models with acute or chronic hypoxia exposure. Many murine models exist to study these conditions; however, there are a variety of different hypoxia exposure protocols used across laboratories. Experimental equipment for hypoxia exposure typically includes flow regulators, nitroge...
Source: Frontiers in Physiology - July 12, 2022 Category: Physiology Source Type: research

BCI-FES With Multimodal Feedback for Motor Recovery Poststroke
In this report, we describe device parameters and intervention protocols of our BCI-FES system which, combined with standard physical rehabilitation approaches, has proven efficacious in treating UE motor impairment in stroke survivors, regardless of level of impairment and chronicity.
Source: Frontiers in Human Neuroscience - July 6, 2022 Category: Neuroscience Source Type: research

Concurrent TMS-fMRI: Technical Challenges, Developments, and Overview of Previous Studies
Transcranial magnetic stimulation (TMS) is a promising treatment modality for psychiatric and neurological disorders. Repetitive TMS (rTMS) is widely used for the treatment of psychiatric and neurological diseases, such as depression, motor stroke, and neuropathic pain. However, the underlying mechanisms of rTMS-mediated neuronal modulation are not fully understood. In this respect, concurrent or simultaneous TMS-fMRI, in which TMS is applied during functional magnetic resonance imaging (fMRI), is a viable tool to gain insights, as it enables an investigation of the immediate effects of TMS. Concurrent application of TMS d...
Source: Frontiers in Psychiatry - April 21, 2022 Category: Psychiatry Source Type: research

The Case for, and Challenges of, Human Cardiac Tissue in Advancing Phosphoprotein Research
Cardiovascular disease (CVD) and stroke affect over 92 million Americans and account for nearly 1 out of 3 deaths in the US. The use of animal models in cardiovascular research has led to considerable advances in treatment and in our understanding of the pathophysiology of many CVDs. Still, animals may not fully recapitulate human disease states; species differences have long been postulated to be one of the main reasons for a failure of translation between animals and humans in drug discovery and development. Indeed, it has become increasingly clear over the past few decades that to answer certain biomedical questions, li...
Source: Frontiers in Physiology - March 23, 2022 Category: Physiology Source Type: research