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Total 46 results found since Jan 2013.

Quality of anticoagulant control and patient experience associated with long-term warfarin in Canadian patients with non-valvular atrial fibrillation: A multicentre, prospective study
ConclusionsWe showed excellent overall TTR in an observed Canadian cohort, with monitoring through a dedicated anticoagulant clinic being associated with a statistically and clinically significant improvement in TTR. The burden of warfarin therapy on patients ’ health related quality of life or daily work and activities was low.
Source: PLoS One - April 18, 2023 Category: Biomedical Science Authors: Rita Selby Source Type: research

Design and Rationale of the Home Blood Pressure Telemonitoring Linked with Community Health Workers to Improve Blood Pressure (LINKED-BP) Program
This study is part of the American Heart Association RESTORE (AddREssing Social Determinants TO pRevent hypErtension) Network. This study aims to examine the effect of the LINKED-BP Program on BP reduction and to evaluate the reach, adoption, sustainability, and cost-effectiveness of the intervention.METHODS: Using a hybrid type I effectiveness-implementation design, 600 adults who have elevated BP or untreated stage 1 hypertension without diabetes, chronic kidney disease, history of cardiovascular disease (stroke or coronary heart disease) and age < 65 years will be recruited from 20 primary care practices including co...
Source: American Journal of Hypertension - April 16, 2023 Category: Cardiology Authors: Yvonne Commodore-Mensah Xiaoyue Liu Oluwabunmi Ogungbe Chidinma Ibe Johnitta Amihere Margaret Mensa Seth S Martin Deidra Crews Kathryn A Carson Lisa A Cooper Cheryl R Himmelfarb Source Type: research

Why do people take part in atrial fibrillation screening? Qualitative interview study in English primary care
Conclusions Participants assessed the SAFER AF screening programme to be a legitimate, relevant and safe screening opportunity, and complied obediently with what they perceived to be a recommendation to take part. Their unreserved acceptance of screening benefit and lack of awareness of potential harms suggests that uptake would be high but reinforces the importance of ensuring participants receive balanced information about AF screening initiatives. Trial registration number ISRCTN16939438; Pre-results.
Source: BMJ Open - March 16, 2022 Category: General Medicine Authors: Hoare, S., Powell, A., Modi, R. N., Armstrong, N., Griffin, S. J., Mant, J., Burt, J., The SAFER Authorship Group, Dymond, Hobbs, Johnson, McManus, Williams Tags: Open access, Public health Source Type: research

Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study
Conclusions A substantial proportion of the UK population carry genetic variants that reduce metabolism of clopidogrel to its active form. In family practice patients on clopidogrel, CYP2C19 LoF variants are associated with substantially higher incidence of ischaemic events. Genotype-guided selection of antiplatelet medications may improve outcomes in patients carrying CYP2C19 genetic variants.
Source: BMJ Open - December 13, 2021 Category: General Medicine Authors: Pilling, L. C., Türkmen, D., Fullalove, H., Atkins, J. L., Delgado, J., Kuo, C.-L., Kuchel, G. A., Ferrucci, L., Bowden, J., Masoli, J. A. H., Melzer, D. Tags: Open access, Cardiovascular medicine Source Type: research

Prevalence of and Factors Associated With the Prescription of Fibrates Among Patients Receiving Lipid-Lowering Drugs in Germany
Abstract: Little recent data are available about the patterns of prescription for fibrates in patients followed in primary care practices. Therefore, the goal of this study was to analyze the prevalence of and the factors associated with the use of fibrates among patients receiving lipid-lowering drugs in Germany. The study included patients aged ≥18 years with at least 1 visit to 1 of 1070 general practices in Germany between January and December 2019. Lipid-lowering drugs included statins (without and with ezetimibe) and fibrates. The prevalence of the prescription of fibrates corresponded to the number of patients...
Source: Journal of Cardiovascular Pharmacology - December 1, 2021 Category: Cardiology Tags: Original Article Source Type: research

Women with Polycystic Ovary Syndrome have an increased risk of major cardiovascular events: a population study
CONCLUSIONS: The risk of incident MI, angina and revascularization is increased in young women with PCOS. Weight and T2DM are potentially modifiable risk factors amenable to intervention.PMID:34061968 | DOI:10.1210/clinem/dgab392
Source: The Journal of Clinical Endocrinology and Metabolism - June 1, 2021 Category: Endocrinology Authors: Thomas R Berni Christopher L Morgan D Aled Rees Source Type: research

Evidence-based early stage type 2 diabetes follow-up in Belgian primary care practices: Impact of multi-professional teams and care protocols
The consequences of late detected or poorly diagnosed and monitored diabetes are considerable. The chronic hyperglycemia of diabetes is associated with long-term dysfunction, and failure of the eyes, kidneys, nerves, heart, and blood vessels. Individuals with undiagnosed type 2 diabetes (T2D) are also at significantly higher risk for stroke, coronary heart disease, and peripheral vascular disease [1]. These consequences increase the importance of early detection and a qualitative follow-up. Fortunately, the evidence on optimal care provision for people diagnosed with T2D is numerous.
Source: Primary Care Diabetes - October 12, 2020 Category: Primary Care Authors: Evi Matthys, Peter Van Bogaert, Sabrina Blommaert, Liesbeth Verdonck, Roy Remmen Tags: Original research Source Type: research

Designing and Evaluating a Prediabetes Shared Decision Aid
Discussion: It was feasible to cocreate a prediabetes shared decision aid within a PASAC and implement the tool within a primary care setting. Patients and clinicians reported a prediabetes discussion, which may mitigate rates of progression to diabetes and associated complications. Future research should evaluate which of the intervention components most effectively promotes discussion of prediabetes within a primary care setting.
Source: Journal of the American Board of Family Medicine - March 15, 2020 Category: Primary Care Authors: Careyva, B. A., Shaak, K., Burgess, N. M., Johnson, M. B., Banerjee, E. S., Chung, Y., Davis, A. N., Payton, C. Tags: Brief Report Source Type: research

Design and rationale of a pragmatic trial integrating routine screening for atrial fibrillation at primary care visits: The VITAL-AF trial
Publication date: Available online 22 June 2019Source: American Heart JournalAuthor(s): Jeffrey M. Ashburner, Steven J. Atlas, David D. McManus, Yuchiao Chang, Ana T. Trisini Lipsanopoulos, Leila H. Borowsky, Wyliena Guan, Wei He, Patrick T. Ellinor, Daniel E. Singer, Steven A. LubitzAbstractGiven the preventable morbidity and mortality associated with atrial fibrillation (AF), increased awareness of undiagnosed AF, and advances in mobile ECG technology, there is a critical need to assess the effectiveness of using such technology to routinely screen for AF in clinical practice. VITAL-AF is a pragmatic trial that will test...
Source: American Heart Journal - June 24, 2019 Category: Cardiology Source Type: research