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Total 35 results found since Jan 2013.

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

Post-Polio Syndrome
Post-Polio syndrome information compiled by the National Institute of Neurological Disorders and Stroke (NINDS).
Source: NINDS Disorders: National Institute of Neurological Disorders and Stroke - October 26, 2014 Category: Neurology Source Type: research

Assessment of exercise stroke volume and its prediction from oxygen pulse in Paralympic Athletes with locomotor impairments: cardiac long-term adaptations are possible.
The determinants of cardiac output (CO) during exercise, i.e., stroke volume (SV) and heart rate (HR), could differ in Paralympic athletes (PAthl) with spinal cord injury (SCI) with respect to PAthl with locomotor impairments caused by different health conditions (HC). The purposes of the present study were the comparisons of two groups of PAthl, one with SCI and one with either amputation (AMP) or post poliomyelitis syndrome (PM), assessing the: (1) peak cardiorespiratory responses and determinants (SV and HR) of CO during maximal and submaximal arm cranking exercise (ACE), respectively; (2) correlations between peak oxyg...
Source: Frontiers in Physiology - January 7, 2020 Category: Physiology Source Type: research

The immunocompromised district in dermatology: A unifying pathogenic view of the regional immune dysregulation
Abstract: Besides the systemic immune deficiency, a sectorial default in immune control may occur in immunocompetent subjects. This regional immune defect can appear and remain confined to differently damaged skin areas, lately labeled immunocompromised districts (ICDs).An ICD is a skin area more vulnerable than the rest of the body for genetic or acquired reasons. Its vulnerability mainly consists in a local dysregulation of the immune control, which often facilitates (but sometimes hinders) the local onset of immunity-related eruptions or skin disorders.The factors responsible for localized immune dysregulation are multi...
Source: Clinics in Dermatology - August 25, 2014 Category: Dermatology Authors: Vincenzo Ruocco, Eleonora Ruocco, Vincenzo Piccolo, Giampiero Brunetti, Luigi Pio Guerrera, Ronni Wolf Source Type: research

The immunocompromised district in dermatology: A unifying pathogenic view of the regional immune dysregulation.
Abstract Besides the systemic immune deficiency, a sectorial default in immune control may occur in immunocompetent subjects. This regional immune defect can appear and remain confined to differently damaged skin areas, lately labeled immunocompromised districts (ICDs). An ICD is a skin area more vulnerable than the rest of the body for genetic or acquired reasons. Its vulnerability mainly consists in a local dysregulation of the immune control, which often facilitates (but sometimes hinders) the local onset of immunity-related eruptions or skin disorders. The factors responsible for localized immune dysregulation...
Source: Herpes - August 30, 2014 Category: Infectious Diseases Authors: Ruocco V, Ruocco E, Piccolo V, Brunetti G, Guerrera LP, Wolf R Tags: Clin Dermatol Source Type: research

CDC's Mission: Protecting the Health of Americans
There is no doubt Ebola will rank as the biggest public health story of 2014, both here in the United States and around the world: more people sickened by Ebola than ever before in history, more people dying, and more understanding of how the health of one nation affects the health of us all. Today, more than 170 of CDC's top health professionals are in West Africa working to stop the current Ebola epidemic and leave behind stronger public health systems. Many hundreds more support their work at home. Leaving behind better capacities to find, stop, and prevent health threats in affected countries will help prevent the ...
Source: Healthy Living - The Huffington Post - December 24, 2014 Category: Consumer Health News Source Type: news

Dual mobility cup for prevention of early total hip arthroplasty dislocation in patients with neurological disorders
Conclusion The dual mobility cup is effective in the prevention of early dislocation in patients with muscle weakness due to neurological disorders. Long-term follow-up is needed for the assessment of late dislocation, as well as the rate of loosening in this group of patients.
Source: European Orthopaedics and Traumatology - November 21, 2015 Category: Orthopaedics Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

What Causes Muscle Weakness?
Discussion Muscle tone is the slight tension that is felt in a muscle when it is voluntarily relaxed. It can be assessed by asking the patient to relax and then taking the muscles through a range of motion such as moving the wrists, forearm and upper arm. Muscle strength is the muscle’s force against active resistance. Impaired strength is called weakness or paresis. There are 5 levels of muscle strength. 0 = No muscle contraction detected 1 = Barely detected flicker of contraction 2 = Active movement with gravity eliminated 3 = Active movement against gravity 4 = Active movement against gravity and some resistance ...
Source: PediatricEducation.org - December 9, 2013 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Design and Functional Evaluation of a Quasi-Passive Compliant Stance Control Knee–Ankle–Foot Orthosis
In this paper, we present the mechanical design, control algorithm, and functional evaluation of a quasi-passive compliant stance control knee–ankle–foot orthosis. The orthosis implements a spring in parallel with the knee joint during the stance phase of the gait and allows free rotation during the swing phase. The design is inspired by the moment-angle analysis of the knee joint revealing that the knee function approximates that of a linear torsional spring in the stance phase of the gait. Our orthosis aims to restore the natural function of a knee that is impaired by injury, stroke, post-polio, multiple sc...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 1, 2014 Category: Neuroscience Source Type: research

What Causes Ataxia?
Discussion Coordination and balance problems are caused by various problems affecting the central and peripheral nervous system. Normal development of a child or weakness of a child are commonly mistaken for true ataxia. Ataxia specifically refers to “…impairment of the coordination of movement without loss of muscle strength.” If it is purely due to abnormalities of the cerebellum then there should be no changes in mental status, sensation or weakness. Sometimes it is difficult to determine if there are abnormalities in other areas. For example, Guillian-Barre often presents with difficulty or clumsy wal...
Source: PediatricEducation.org - March 31, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Here Are the Real Victims of Pakistan’s War on the Taliban
An elderly displaced man carries a sack of rations on his shoulder. The Pakistan Army has distributed 30,000 ration packs of 110 kg each. Credit: Ashfaq Yusufzai/IPSBy Ashfaq YusufzaiPESHAWAR, Pakistan, Jul 1 2014 (IPS) Three days ago, Rameela Bibi was the mother of a month-old baby boy. He died in her arms on Jun. 28, of a chest infection that he contracted when the family fled their home in Pakistan’s North Waziristan Agency, where a full-scale military offensive against the Taliban has forced nearly half a million people to flee. Weeping uncontrollable, Bibi struggles to recount her story. “My son was born on Jul. 2...
Source: IPS Inter Press Service - Health - July 1, 2014 Category: Global & Universal Authors: Ashfaq Yusufzai Tags: Aid Armed Conflicts Asia-Pacific Development & Aid Economy & Trade Editors' Choice Environment Featured Food & Agriculture Gender Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees Population Povert Source Type: news

Segmental immune disorders resulting from neurologic injuries
Abstract: The immunocompromised cutaneous district (ICD) is a novel pathogenic concept that refers to the occurrence of opportunistic skin disorders (such as infections, malignancies, and immune diseases) at a cutaneous site previously marked by a damaging event, usually involving the local lymph network or peripheral sensory nerves. In addition to herpetic infections, which are notoriously harmful for sensory nerve fibers and therefore already included among the potential causes of ICD, there are a large and variegate group of further neurologic diseases, both peripheral (carpal tunnel syndrome, facial nerve palsy, and tr...
Source: Clinics in Dermatology - August 25, 2014 Category: Dermatology Authors: Vincenzo Piccolo, Teresa Russo, Domenico Bove, Adone Baroni Source Type: research

We Must Beat Alzheimer's Before It Beats Us! And Here's How!
Alzheimer's Has Become the Scariest Disease of Later Life It's true. In a new Age Wave/Merrill Lynch study titled Health and Retirement: Planning for the Great Unknown, we surveyed a representative sample of over 3,000 Americans to uncover both their hopes and their concerns about health and healthcare expenses. Overwhelmingly, the study respondents said that the most important ingredient for a happy retirement is health. And while all diseases can disrupt both health and wealth in retirement, people of all ages now say the scariest disabling condition in later life is Alzheimer's disease. In fact, Alzheimer's was cited...
Source: Healthy Living - The Huffington Post - November 20, 2014 Category: Consumer Health News Source Type: news