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Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Management of Neurologic Manifestations in Patients with Liver Disease
Opinion statement Liver disease, both in its acute and chronic forms, can be associated with a wide spectrum of neurologic manifestations, both central and peripheral, ranging in severity from subclinical changes to neurocritical conditions. Neurologists are frequently consulted to participate in their management. In this review, we present an overview of management strategies for patients with hepatic disease whose clinical course is complicated by neurologic manifestations. Type A hepatic encephalopathy (HE), which occurs in acute liver failure, is a neurologic emergency, and multiple measures should be taken t...
Source: Current Treatment Options in Neurology - June 16, 2016 Category: Neurology Source Type: research

Management of Neurologic Manifestations in Patients with Liver Disease.
Abstract OPINION STATEMENT: Liver disease, both in its acute and chronic forms, can be associated with a wide spectrum of neurologic manifestations, both central and peripheral, ranging in severity from subclinical changes to neurocritical conditions. Neurologists are frequently consulted to participate in their management. In this review, we present an overview of management strategies for patients with hepatic disease whose clinical course is complicated by neurologic manifestations. Type A hepatic encephalopathy (HE), which occurs in acute liver failure, is a neurologic emergency, and multiple measures should b...
Source: Epilepsy Curr - June 19, 2016 Category: Neurology Authors: Ferro JM, Viana P, Santos P Tags: Curr Treat Options Neurol Source Type: research

Neurological Complications Prevalence and Long-Term Survival After Liver Transplantation
Conclusions: Neurological complications led to longer hospital stays with greater early morbidity and mortality. Knowledge of these complications appears to be extremely important for the multidisciplinary transplantation team to decrease its prevalence as well as to diagnose and treat early.
Source: Transplantation Proceedings - April 1, 2013 Category: Transplant Surgery Authors: R.C. Colombari, E.C. de Ataíde, E.Y. Udo, A.L.E. Falcão, L.C. Martins, I.F.S.F. Boin Tags: Liver Transplantation Source Type: research

Ten-point plan to tackle liver disease published
"Doctors call for tougher laws on alcohol abuse to tackle liver disease crisis," The Guardian reports. But this is just one of 10 recommendations for tackling the burden of liver disease published in a special report in The Lancet.The report paints a grim picture of an emerging crisis in liver disease in the UK, saying it is one of the few countries in Europe where liver disease and deaths have actually increased rapidly over the last 30 years. It concludes with 10 recommendations to tackle the burden of liver disease.The media has approached the recommendations from many different angles, with many sources only ...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise QA articles Source Type: news

Framingham score, renal dysfunction, and cardiovascular risk in liver transplant patients
Cardiovascular (CV) events represent major impediments to the long‐term survival of liver transplantation (LT) patients. The aim of this study was to assess whether the Framingham risk score (FRS) at transplantation can predict the development of post‐LT cardiovascular events (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV risk factors, and CVEs occurring after LT (ischemic heart disease, stroke, heart failure, de novo arrhythmias, and peripheral arterial disease) were recorded. In total, 250 patients (69.6% men) with a median age of 56 years (range, 18‐68 years) were included...
Source: Liver Transplantation - May 26, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Article Source Type: research

Donor risk factors in orthotopic liver transplant: analysis of the OPTN/UNOS registry.
This study of the United Network for Organ Sharing registry data analyzed reputed donor factors using the post-MELD data and evaluated them further in HCV positive and HCV negative recipients with hepatic cirrhosis to develop a modified DRI (mDRI). We found that HCV negative cirrhotic recipients have generally higher tolerance against inferior qualities of donors than HCV positive cirrhotic patients. In addition, the results revealed the post-MELD prognostic factors that should be considered in the donor procurement processes. The group of "all recipients" and the subset of HCV positive cirrhotic recipients showed a simila...
Source: Clinical Transplants - November 20, 2015 Category: Transplant Surgery Tags: Clin Transpl Source Type: research

Frequency of Cardiovascular Events and Effect on Survival in Liver Transplant Recipients for Cirrhosis Due to Alcoholic or Nonalcoholic Steatohepatitis.
CONCLUSIONS: Cardiovascular events occurred with similar frequency in transplant recipients for nonalcoholic steatohepatitis or alcoholic cirrhosis. Patient survival was affected in both groups, but male patients with concomitant hepatitis C virus infection remained at higher risk for a cardiovascular event after liver transplant. Development of a cardiac evaluation protocol for liver transplant recipients could help monitor these patients. PMID: 26581602 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - November 17, 2015 Category: Transplant Surgery Authors: Piazza NA, Singal AK Tags: Exp Clin Transplant Source Type: research

Imaging of a Fatal Air Embolism from ERCP (P4.363)
CONCLUSIONS: Though most of the occurrences in relation to ERCP are portal venous air embolisms, which are absorbed spontaneously, serious and sometimes fatal complications have occurred including arterial air embolisms causing multiorgan damage including cerebral infarcts. Case history, pertinent imaging and pathological findings are discussed to bring awareness of this rare complication of ERCP and emphasize its early recognition. Disclosure: Dr. Jens has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ibrahimi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Jens, W., Lee, A., Ibrahimi, M. Tags: Cerebrovascular Case Reports Source Type: research

Characteristics and Performance of Unilateral Kidney Transplants from Deceased Donors.
CONCLUSIONS: A large number of discarded kidneys were procured from donors whose contralateral kidneys were transplanted with good post-transplant outcomes. PMID: 29217537 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - December 7, 2017 Category: Urology & Nephrology Authors: Husain SA, Chiles MC, Lee S, Pastan SO, Patzer RE, Tanriover B, Ratner LE, Mohan S Tags: Clin J Am Soc Nephrol Source Type: research

Heart transplants from donors with hepatitis C may be safe and could help decrease organ shortage
(American Heart Association) One-year survival was 90% for adults with severe heart failure who received a heart transplant from a donor with hepatitis C, which was nearly identical to those who received a heart from donors who did not have hepatitis C (91%). Rates of organ rejection, stroke and kidney dialysis were similar between the two groups. More research is needed to assess longer-term results, however, increased use of hearts from donors with hepatitis C could help overcome the national shortage of donor organs.
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news

Complications of Hepatocellular Carcinoma patients post living Donor Liver Transplantation
ConclusionThere was no statistical significance for those within or out side the Milan criteria or UCSF criteria and its impact on the occurrence of graft rejection, sepsis, vascular complications, death, HCC recurrence and biliary complications post-transplant.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research