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Infectious Disease: Osteomyelitis

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Total 16 results found since Jan 2013.

Increased perioperative C-reactive protein and decreased postoperative albumin is associated with acute posttraumatic osteomyelitis in patients with high-energy tibial fractures
Early diagnosis of acute posttraumatic osteomyelitis (POM) is of vital importance for avoiding devastating complications. Diagnosing POM is difficult due to the lack of a highly specific and sensitive test, such as in myocardial infarct, stroke and intracranial bleeding. Serum inflammatory markers, C-reactive protein (CRP), procalcitonin (PCT), white blood cells (WBC) can support clinical findings but they are not able to differentiate between inflammatory response to infection and the host response to non-infection insult with high specificity and sensitivity.
Source: Injury - March 5, 2019 Category: Orthopaedics Authors: Matja ž Groznik, Matej Cimerman, Lara Lusa, Nina Ružić Gorenjec, Alojz Ihan Source Type: research

Fatal Progression of Gorham-Stout Disease with Skull Base Osteomyelitis and Lateral Medullary Syndrome.
We present the case of a 27-year-old man diagnosed with GSD with involvement of the maxillofacial bones and skull base. The patient developed SBO; LMS resulted from progressive osteolysis, and the patient died of associated brainstem stroke. Careful follow-up with special emphasis on the early detection of intracranial complications is critical in patients presenting with progressive GSD with involvement of the skull base. PMID: 30799352 [PubMed - as supplied by publisher]
Source: Internal Medicine - February 26, 2019 Category: Internal Medicine Tags: Intern Med Source Type: research

Vitamin D supplementation for sickle cell disease.
CONCLUSIONS: We included only one low-quality clinical study which had a high risk of bias with regards to incomplete outcome data. Therefore, we consider that the evidence is not of sufficient quality to guide clinical practice. Until further evidence becomes available, clinicians should consider the relevant existing guidelines for vitamin D supplementation (e.g. the Endocrine Society Clinical Practice Guidelines) and dietary reference intakes for calcium and vitamin D (e.g. from the USA Institute of Medicine). Evidence of vitamin D supplementation in sickle cell disease from high quality studies is needed. Well-designed...
Source: Cochrane Database of Systematic Reviews - January 20, 2017 Category: Journals (General) Authors: Soe HH, Abas AB, Than NN, Ni H, Singh J, Said AR, Osunkwo I Tags: Cochrane Database Syst Rev Source Type: research

Time interval between infective endocarditis first symptoms and diagnosis: relationship to infective endocarditis characteristics, microorganisms and prognosis.
CONCLUSIONS: The time interval between IE first symptoms and diagnosis is closely related to the IE clinical presentation, patient characteristics and causative microorganism. Better prognosis reported in late-diagnosed IE may be related to a higher rate of valvular surgery. KEY MESSAGES Infective endocarditis, which time interval between first symptoms and diagnosis was less than one month, were mainly due to Staphylococcus aureus in France. Staphylococcus aureus infective endocarditis were associated with septic shock, transient ischemic attack or stroke and higher mortality rates than infective endocarditis due to other...
Source: Annals of Medicine - November 5, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research

Symptomatic stroke complicating central skull base osteomyelitis following otitis media in a 2-Year Old Boy: Case Report and Review of the Literature
This report describes the first case of symptomatic ischaemic stroke secondary to SBO in an immunocompetent child. We review the literature of the management and the potential cerebrovascular complications of central SBO in children secondary to otolaryngological infection.
Source: International Journal of Pediatric Otorhinolaryngology - August 5, 2016 Category: ENT & OMF Authors: Eliz Kilich, Reena Dwivedi, Shelley Segal, Sandeep Jayawant, Manish Sadarangani Tags: Case Report Source Type: research

Mycotic aneurysm of the extracranial internal carotid artery - resect and ligate or reconstruct?
This report highlights a case of ECA aneurysm infection presenting with stroke and an occluded internal carotid artery, likely due to microbial arteritis on a background of osteomyelitis. Operative intervention was performed to definitively treat the infection and prevent the potential associated complications.
Source: Annals of Vascular Surgery - May 27, 2016 Category: Surgery Authors: A.C. Rogers, M. Bourke, A.S. Galbraith, A.G. Ryan, K.S.C. Cross, M.P. McMonagle Source Type: research

Mycotic Aneurysm of the Extracranial Internal Carotid Artery, Resect and Ligate or Reconstruct?
This report highlights a case of ECA-aneurysm infection presenting with stroke and an occluded internal carotid artery, likely due to microbial arteritis on a background of osteomyelitis. Operative intervention was performed to definitively treat the infection and prevent the potential associated complications.
Source: Annals of Vascular Surgery - May 27, 2016 Category: Surgery Authors: Ail ín C. Rogers, Michael Bourke, Adam S. Galbraith, Anthony G. Ryan, K. Simon C. Cross, Morgan P. McMonagle Tags: Case Report Source Type: research

Mycotic aneurysm of the extracranial internal carotid artery - resect and ligate or reconstruct?
This report highlights a case of ECA aneurysm infection presenting with stroke and an occluded internal carotid artery, likely due to microbial arteritis on a background of osteomyelitis. Operative intervention was performed to definitively treat the infection and prevent the potential associated complications.
Source: Annals of Vascular Surgery - May 27, 2016 Category: Surgery Authors: A.C. Rogers, M. Bourke, A.S. Galbraith, A.G. Ryan, K.S.C. Cross, M.P. McMonagle Source Type: research

Headache and Facial Pain in Sickle Cell Disease
Abstract Children and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 %). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit from comprehensive headache treatment plans that include abortive therapy, pr...
Source: Current Pain and Headache Reports - February 15, 2016 Category: Neurology Source Type: research

Skull base osteomyelitis missed in mastoidectomy for cholesteatoma.
Conclusions A high suspicion of skull base involvement should be warranted, even if radiological findings are not atypical, in cases of chronic otitis media (COM) with cholesteatoma. Objective To investigate some clues indicating the development of skull base osteomyelitis (SBO) in patients who received mastoidectomy, through reviewing pre-operative temporal bone computed tomography (TBCT). Method Retrospective review of patients with SBO after mastoidectomy for COM. A total of five patients with SBO after mastoidectomy with available pre-operative TBCTs were enrolled in this study. Results All patients were diagnosed as C...
Source: Acta Oto-Laryngologica - January 15, 2016 Category: ENT & OMF Authors: Lee HS, Yang CJ, Lee JH, Ahn JH Tags: Acta Otolaryngol Source Type: research

Outcomes of Chopart Amputation in a Tertiary Referral Diabetic Foot Clinic: Data From a Consecutive Series of 83 Hospitalized Patients
Publication date: Available online 24 November 2015 Source:The Journal of Foot and Ankle Surgery Author(s): Ezio Faglia, Giacomo Clerici, Robert Frykberg, Maurizio Caminiti, Vincenzo Curci, Francesco Cetta, Vincenzo Prisco, Rosaria Greco, Marco Prisco, Alberto Morabito The purpose of the present retrospective study was to evaluate the outcomes (ie, ulcer recurrence, major amputation, death) in diabetic patients undergoing Chopart amputation because of deep infection or gangrene extending to the midfoot. From 2009 to 2011, 83 patients, aged 71.4 ± 9.3 years, underwent a midtarsal amputation and were followed...
Source: The Journal of Foot and Ankle Surgery - November 26, 2015 Category: Orthopaedics Source Type: research

Cervical aspergillosis with dissemination to the central nervous system: Case reports and review of the literature.
CONCLUSION: IA must be considered a possibility whenever an immunocompromised patient presents with a new brain lesion. These lesions require surgical evacuation, a procedure that allows for diagnostic confirmation and enhances prognosis. Appropriate anti-fungal therapy must be started as soon as the diagnosis is confirmed. In addition, the patient's neurological exam must be repeated and images obtained periodically to monitor treatment and detect possible recurrences. PMID: 26600985 [PubMed - as supplied by publisher]
Source: Surgical Neurology International - November 25, 2015 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Serious Complications from Staphylococcal aureus in Atopic Dermatitis
We report two unusual cases of systemic illness in individuals with AD. One developed infective endocarditis followed by a stroke and the other developed septic arthritis and osteomyelitis. We performed an extensive literature review of reported systemic complications caused by S. aureus in patients with AD. Although reports are rare, practitioners should be aware of these important, albeit unlikely, complications of staphylococcal superinfections in individuals with AD.
Source: Pediatric Dermatology - September 4, 2015 Category: Dermatology Authors: Devika Patel, Marla N. Jahnke Tags: Review Source Type: research

Increased risk of dementia among chronic osteomyelitis patients
This study investigates whether COM increases the risk of dementia. Taiwanese National Health Insurance (NHI) inpatient claims were used to identify 17,238 patients newly diagnosed with COM from 2000 to 2008, and 68,944 age- and gender-matched patients without COM were randomly selected for comparison. Risks of dementia associated with COM and comorbidities, including hypertension, diabetes, stroke, hyperlipidemia, and depression, were evaluated using data from the end of 2011. Dementia risk was 1.6-fold higher (95 % confidence interval [CI]: 1.4–1.83) in the COM cohort than in the control group, calculated using the mu...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 1, 2015 Category: Microbiology Source Type: research

Increased depression risk among patients with chronic osteomyelitis
Inflammatory processes, which provoke alternations of neurotransmitter metabolism, neuroendocrine function, and neuroplasticity in the brain, might promote depression. In depression patients who do not exhibit risk factors, including hypertension, diabetes, coronary heart disease, stroke, Parkinson's disease and dementia, particularly in young people, inflammation is a likely risk factor for depression. We explored whether chronic osteomyelitis (COM), a chronic inflammatory disease, increases depression risk.
Source: Journal of Psychosomatic Research - September 14, 2014 Category: Psychiatry & Psychology Authors: Chun-Hung Tseng, Wei-Shih Huang, Chih-Hsin Muo, Yen-Jung Chang, Chia-Hung Kao Source Type: research

Increased risk of coronary heart disease in patients with chronic osteomyelitis: a population-based study in a cohort of 23 million
Conclusions This study demonstrates that COM is an independent risk factor for CHD, particularly in the younger population. Further studies are necessary to explore the underlying mechanisms linking COM and CHD.
Source: Heart - August 21, 2014 Category: Cardiology Authors: Hsiao, L.-C., Muo, C.-H., Chen, Y.-C., Chou, C.-Y., Tseng, C.-H., Chang, K.-C. Tags: Health policy, Drugs: cardiovascular system, Hypertension, Epidemiology, Metabolic disorders Coronary artery disease Source Type: research