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Infectious Disease: COVID-19

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Total 517 results found since Jan 2013.

Stroke in a Feverish Patient with COVID-19 Infection and Unknown Endocarditis.
Authors: Mantero V, Rigamonti A, Basilico P, Sangalli D, Scaccabarozzi C, Salmaggi A PMID: 33029982 [PubMed]
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Cerebral Herniation Secondary to Stroke-associated Hemorrhagic Transformation, Fulminant Cerebral Edema in Setting of COVID-19 Associated ARDS and Active Malignancy
We present the case of a very rapid neurologic and radiographic decline of a patient with an acute ischemic stroke who developed rapid fulminant cerebral edema leading to herniation in the setting of hypercarbic respiratory failure attributed to SARS-CoV-2 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Stephan A. Mayer, Justin Santarelli, Chirag Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

Letter to the Editor regarding: Critical considerations for stroke management during COVID-19 pandemic by Inglis et al., Heart Lung Circ. 2020;29(9): 1263 –1267.
Source: Heart, Lung and Circulation - October 9, 2020 Category: Cardiology Authors: Skye Coote, Dominique A. Cadilhac, Elizabeth O ’Brien, Sandy Middleton, Acute Stroke Nurses Education Network (ASNEN) Steering Committee Tags: Letter to the Editor Source Type: research

Stroke and Thromboprophylaxis in the era of COVID-19
In the rapidly evolving COVID-19 pandemic, many patients presenting with acute ischemic stroke may be potentially infected with the Severe Acute Respiratory Syndrome Coronavirus (SARS CoV-2) agent. As stroke patients are often unable to give an adequate history of preceding COVID-19 symptoms, all stroke patients in areas with high prevalence of community transmission should be considered potential cases. Observational studies have suggested an increased tendency for thrombotic events in patients infected with SARS CoV-2.
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2020 Category: Neurology Authors: Alice Ma, Carlos S. Kase, Ashkan Shoamanesh, Mohamad Abdalkader, Aleksandra Pikula, Anvitha Sathya, Luciana Catanese, Alun T. Ellis, Thanh N. Nguyen Source Type: research

Stroke Care Within the COVID-19 Pandemic —Increasing Awareness of Transient and Mild Stroke Symptoms Needed
Conclusions: During the COVID-19 pandemic, resources of the healthcare system in a primary care university hospital in Germany still allowed for unchanged numbers of recanalization procedures due to ischemic stroke. However, the numbers of patients admitted to the hospital specifically due to ischemic stroke or TIA decreased, suggesting that the awareness for non-disabling stroke symptoms has to be increased.
Source: Frontiers in Neurology - October 9, 2020 Category: Neurology Source Type: research

COVID-19 Era Stroke Service: Virtually Normal
ConclusionsZoom conferences are a promising technology for stroke services. Further studies are needed to further elucidate their benefits and drawbacks.
Source: Current Treatment Options in Neurology - October 8, 2020 Category: Neurology Source Type: research

The stroke mothership model survived during COVID-19 era: an observational single-center study in Emilia-Romagna, Italy
ConclusionDuring COVID-19 pandemic, TIA and minor stroke consistently reduced compared to the same timeframe in 2019. Longer stroke-to-call and door-to-scan times, attributable to change in citizen behavior and screening at hospital arrival, did not impact on stroke-to-treatment time. Mothership model might have minimized the effects of the pandemic on the stroke care organization.
Source: Neurological Sciences - October 8, 2020 Category: Neurology Source Type: research

Cross-Talk Between Key Players in Patients with COVID-19 and Ischemic Stroke: A  Review on Neurobiological Insight of the Pandemic
AbstractThe global pandemic of novel coronavirus disease 2019 (COVID-19) has taken the entire human race by surprise and led to an unprecedented number of mortalities worldwide so far. Current clinical studies have interpreted that angiotensin-converting enzyme 2 (ACE2) is the host receptor for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). In addition, ACE2 is the major component of the renin-angiotensin system. ACE2 deteriorates angiotensin II, a peptide that is responsible for the promotion of stroke. The downregulation of ACE2 further activates an immunological cascade. Thus, researchers need to explore ...
Source: Molecular Neurobiology - October 7, 2020 Category: Neurology Source Type: research

Impact of COVID-19 on stroke caseload in a major HyperAcute Stroke Unit
Northwick Park Hospital in London, United Kingdom (UK) is one of the busiest stroke units in the country and is located in one of the areas most heavily affected by the COVID-19 pandemic in the first half of 2020. Admissions to the stroke unit and changes during the peak of COVID-19 were reviewed. Compared with the previous year, mean 96 patients were admitted with suspected stroke during April and May 2020 compared with mean 116 per month in non-COVID periods, ratio 0.82, P=0.01. This reduction involved both strokes and mimics and was unlikely to have occurred by chance.
Source: Journal of Stroke and Cerebrovascular Diseases - October 5, 2020 Category: Neurology Authors: Fionn Mag Uidhir, Raj Bathula, Aravinth Sivagnanaratnam, Mudhar Abdul-Saheb, Joseph Devine, David L. Cohen Source Type: research

Impact of COVID-19 on stroke admissions, treatments, and outcomes at a comprehensive stroke centre in the United Kingdom
ConclusionsDuring the COVID-19 pandemic, the number of stroke admissions fell, and stroke severity increased. There was no statistically significant change in the delivery of thrombolysis and mechanical thrombectomy and no increase in mortality.
Source: Neurological Sciences - October 5, 2020 Category: Neurology Source Type: research

Regional Mechanical Thrombectomy Imaging Protocol in Patients Presenting with Acute Ischemic Stroke during the COVID-19 Pandemic INTERVENTIONAL
CONCLUSIONS: Chest CT provides a pragmatic, rapid additional tool for COVID-19 risk stratification among patients referred for mechanical thrombectomy. Its inclusion in a standardized regional stroke imaging protocol has enabled efficient use of hospital resources with minimal compromise or delay to the overall patient treatment schedule.
Source: American Journal of Neuroradiology - October 5, 2020 Category: Radiology Authors: Dhillon, P. S., Pointon, K., Lenthall, R., Nair, S., Subramanian, G., McConachie, N., Izzath, W. Tags: INTERVENTIONAL Source Type: research

Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis
Conclusions: The occurrence of stroke in patients with COVID-19 infection is uncommon, but it may pose as an important prognostic marker and indicator of severity of infection, by causing large vessels occlusion and exhibiting a thrombo-inflammatory vascular picture. Physicians should be made aware and remain vigilant on the possible two-way relationship between stroke and COVID-19 infection. The rate of stroke among patients with COVID-19 infection may increase in the future as they share the common risk factors.
Source: Frontiers in Neurology - October 5, 2020 Category: Neurology Source Type: research

Multiple embolic stroke on magnetic resonance imaging brain in a COVID-19 case with persistent encephalopathy
The pulmonary manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (COVID-19) are well known. The literature on neurological manifestations and complications in patients with COVID-19 has been increasing but is still sparse. At present, there are only a few reported case reports and clinical studies on neurological manifestations of COVID-19, of which ischemic stroke is one of the most common ones. Coagulopathy and vascular endothelial dysfunction have been proposed as the complications of COVID-19 which can ultimately lead to ischemic stroke.
Source: Clinical Imaging - October 4, 2020 Category: Radiology Authors: Apoorv Prasad, Saurabh Kataria, Samiksha Srivastava, Dhairya A. Lakhani, Shitiz Sriwastava Tags: Neuroradiology Source Type: research

Filling the gaps on stroke research: focus on inflammation and immunity.
Abstract For the last two decades, researchers have placed hopes in a new era in which a combination of reperfusion and neuroprotection would revolutionize the treatment of stroke. Nevertheless, despite the thousands of papers available in the literature showing positive results in preclinical stroke models, randomized clinical trials have failed to show efficacy. It seems clear now that the existing data obtained in preclinical research have depicted an incomplete picture of stroke pathophysiology. In order to ameliorate bench-to-bed translation, in this review we first describe the main actors on stroke inflamma...
Source: Brain, Behavior, and Immunity - October 1, 2020 Category: Neurology Authors: Levard D, Buendia I, Lanquetin A, Glavan M, Vivien D, Rubio M Tags: Brain Behav Immun Source Type: research

Stroke May Be First Symptom of COVID-19 in Younger Patients Stroke May Be First Symptom of COVID-19 in Younger Patients
Stroke can be the first presenting symptom of COVID-19, particularly in patients under the age of 50, new data suggest.Medscape Medical News
Source: Medscape Cardiology Headlines - September 30, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Stroke Systems of Care during the COVID-19 Epidemic in Kobe City
The novel coronavirus disease 2019  (COVID-19), first reported in Wuhan, China, in December 2019, spread worldwide in 2020. As of June 1, 2020, the estimated number of global cases and deaths has exceeded 6 million and 370,000, respectively.1 In Japan, the number of reported cases increased sharply in March 2020, with community tran smission presenting at the highest rate in urban areas, leading to a state of emergency being declared by the Japanese government on April 7. Subsequently, on April 9, the Japan Stroke Society and the Japanese Circulation Society issued a joint statement on the importance of maintaining high-q...
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2020 Category: Neurology Authors: Nobuyuki Ohara, Hirotoshi Imamura, Hidemitsu Adachi, Yoshie Hara, Kohkichi Hosoda, Hidehito Kimura, Kazuyuki Kuwayama, Takashi Mizowaki, Yasuhiko Motooka, Kazuya Nakashima, Narihide Shinoda, Takeshi Takamoto, Yasushi Ueno, Ikuya Yamaura, Chie Yanagihara, Source Type: research

Unusual Pattern of Arterial Macrothrombosis Causing Stroke in a Young Adult Recovered from COVID-19
Coronavirus disease-19 (COVID-19) pandemic continues to grow all over the world. Neurological manifestations related to COVID-19, including acute ischemic Stroke (AIS), have been reported in recent studies. In most of these, the patients are older, have multiple co-morbidities as risk factors for AIS and have developed a severe respiratory illness. Herein, we report a 36-year-old man with no significant past medical history who recently recovered from a mild COVID-19 infection and presented with unusual pattern of arterial macrothrombosis causing AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2020 Category: Neurology Authors: Ashkan Mowla, Saman Sizdahkhani, Maryam Sharifian Dorche, Prad Selvan, Benjamin A. Emanuel, Matthew S. Tenser, Arun P. Amar, William J. Mack Tags: Case Report Source Type: research

The Impact of COVID-19 on Acute Ischemic Stroke Admissions: Analysis from a Community-Based Tertiary Care Center
To evaluate the impact of the COVID-19 pandemic on hospital admissions and outcomes in patients admitted with acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2020 Category: Neurology Authors: Jing Wang, Saqib A. Chaudhry, Pouya Tahsili-Fahadan, Laith R. Altaweel, Sairah Bashir, Zelalem Bahiru, Yun Fang, Adnan I. Qureshi Tags: Original Investigation - Rapid Communications Source Type: research

Time of stroke onset in Coronavirus disease 2019 patients around the globe: a systematic review and analysis.
Coronavirus disease 2019 (COVID-19) rapidly became a pandemic. As of August 29th, 2020, over 24 million cases have been confirmed worldwide1. Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection is associated with diverse neurological manifestations involving both the central and peripheral nervous system2,3. In fact, reports of ischemic stroke in patients with COVID-19 have increasingly been published, suggesting an association between these conditions. It has been proposed that SARS-CoV-2 infection induces a severe inflammatory response and hypercoagulable state, making patients susceptible to thromboti...
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2020 Category: Neurology Authors: Natalia Valencia-Enciso, M ónica Ortiz-Pereira, María Paula Zafra-Sierra, Laura Espinel-Gómez, Hernan Bayona Source Type: research

Stroke care trends during COVID-19 pandemic in Zanjan Province, Iran. From the CASCADE Initiative: statistical analysis plan and preliminary results
This study examines the changes in stroke epidemiology and care during the COVID-19 pandemic in Zanjan Province, Iran.
Source: Journal of Stroke and Cerebrovascular Diseases - September 15, 2020 Category: Neurology Authors: Abdoreza Ghoreishi, Shahram Arsang-Jang, Ziad Sabaa-Ayoun, Nawaf Yassi, P.N. Sylaja, Yama Akbari, Afshin A. Divani, Jose Biller, Thanh Phan, Sandy Steinwender, Brian Silver, Ramin Zand, Hamidon Bin Basri, Omer M. Iqbal, Annemarei Ranta, Sean Ruland, Eliza Source Type: research

Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome by Sex
Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), usually presents as a respiratory illness. Neurological manifestations can be seen in 36.4% of patients.1 Patients with vascular risk factors (VRFs), including history of stroke, tend to have worse prognosis.2 COVID-19 triggers a robust inflammatory response which leads to hypercoagulability and thromboembolism.3 Reports of stroke in patients with COVID-19 are mostly limited to small case series or case reports of ischemic stroke (IS), though intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) have also been reported.
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2020 Category: Neurology Authors: G. Trifan, F.D. Goldenberg, F.C. Caprio, J. Biller, M. Schneck, A. Khaja, T. Terna, J. Brorson, C. Lazaridis, Z. Bulwa, R. Alvarado-Dyer, F.G. Saleh-Velez, S. Prabhakaran, E.M. Liotta, A. Batra, N.J. Reish, S. Ruland, M. Teitcher, W. Taylor, P. De la Pena Source Type: research

The prevalence and predictors of post-stroke depression and anxiety during COVID-19 pandemic
In this study, we evaluated the impact of COVID-19 pandemic on the rates of PSD and PSA.
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2020 Category: Neurology Authors: Zakaria M. Ahmed, Mohamed F. Khalil, Ahmed M. Kohail, Islam F. Eldesouky, Ahmed Elkady, Ashfaq Shuaib Source Type: research

Clinical Characteristics of Stroke with COVID-19: A Systematic Review and Meta-Analysis
The coronavirus disease 2019 (COVID-19) potentially increases the risk of thromboembolism and stroke. Numerous case reports and retrospective cohort studies have been published with mixed characteristics of COVID-19 patients with stroke regarding age, comorbidities, treatment, and outcome. We aimed to depict the frequency and clinical characteristics of COVID-19 patients with stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 28, 2020 Category: Neurology Authors: Mai Yamakawa, Toshiki Kuno, Takahisa Mikami, Hisato Takagi, Gary Gronseth Source Type: research

The effect of COVID-19 on stroke hospitalizations in New York City
Little is known about the effect of the Coronavirus disease 2019 pandemic on stroke care and the impact of the epidemic on acute stroke hospitalizations has not been described.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Charles Esenwa, Michael K. Parides, Daniel L. Labovitz Source Type: research

COVID-19 and Stroke: incidence and etiological description in a high-volume center.
An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2020 Category: Neurology Authors: Manuel Requena, Marta Oliv é, Marian Muchada, Álvaro García-Tornel, Matías Deck, Jesús Juega, Sandra Boned, Noelia Rodríguez-Villatoro, Carlos Piñana, Jorge Pagola, David Rodríguez-Luna, David Hernández, Marta Rubiera, Alejandro Tomasello, Carlos Source Type: research

Environmental factors and hyperacute stroke care activity during the COVID-19 pandemic: An interrupted time-series analysis.
Concerns have arisen regarding patient access and delivery of acute stroke care during the COVID-19 pandemic. We investigated key population level events on activity of the three hyperacute stroke units (HASUs) within Greater Manchester and East Cheshire (GM& EC), whilst adjusting for environmental factors.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2020 Category: Neurology Authors: Matthew Gittins, Christopher Ashton, Neil Holden, Stephen Cross, Srinath Meadipudi, Khalil Kawafi, Ilse Burger, Sarah Rickard, Andy Vail, Jane Molloy, Craig J. Smith Source Type: research

Early speech-language rehabilitation for stroke patients during the Covid-19 outbreak
This article emphasizes the importance of maintaining a high standard quality of care for patients with acute stroke even if usual practices will have to be modified. Authors include rehabilitation as an integral part of stroke recovery. We strongly support this position: in this letter we would like to share our experience of delivering. speech-language rehabilitation for stroke inpatients during the Covid-19 outbreak.
Source: Journal of Stroke and Cerebrovascular Diseases - July 30, 2020 Category: Neurology Authors: Patrizia Mammi, Chiara Bidini, Elena Ablondi, Maria Rosaria David, Rodolfo Brianti Source Type: research

Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19
We present a multicenter case series from 9 centers in the United States of patients with acute neurological deficits consistent with AIS and COVID-19 who were treated with IV tPA.Results: We identified 13 patients (mean age 62 ( ±9.8) years, 9 (69.2%) male).
Source: Journal of Stroke and Cerebrovascular Diseases - July 26, 2020 Category: Neurology Authors: Thiago Carneiro, Jonathan Dashkoff, Lester Y. Leung, Christa O'Hana S. Nobleza, Erika Marulanda-Londono, Mausaminben Hathidara, Sebastian Koch, Nicole Sur, Alexandra Boske, Barbara Voetsch, Hassan Aboul Nour, Daniel J Miller, Ali Daneshmand, Julie Shulman Source Type: research

Care for Patients with Stroke During the COVID-19 Pandemic: Physical Therapy and Rehabilitation Suggestions for Preventing Secondary Stroke
Infection with the novel severe acute respiratory syndrome coronavirus 2 causes the development of the novel 2019 coronavirus disease (COVID-19) and associated clinical symptoms, which typically presents as an upper respiratory syndrome such as pneumonia. Growing evidence indicates an increased prevalence of neurological involvement (e.g., in the form of stroke) during virus infection. COVID-19 has been suggested to be more than a lung infection because it affects the vasculature of the lungs and other organs and increases the risk of thrombosis.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2020 Category: Neurology Authors: Chien-Chih Wang, Jian-Kang Chao, Mong-Lien Wang, Yi-Ping Yang, Chien-Shiu Chien, Wei-Yi Lai, Yi-Chiang Yang, Yu-Hui Chang, Chen-Liang Chou, Chung-Lan Kao Source Type: research

Current Recommendations for the Management of Stroke Patients in the Middle East in the Era of COVID-19 Pandemic; Statement from the MENA SINO
COVID-19 pandemic has led to a change in the way we manage acute medical illnesses. This pandemic had a negative impact on stroke care worldwide. The World Stroke Organization (WSO) has raised concerns due to the lack of available care and compromised acute stroke services globally. The numbers of thrombolysis and thrombectomy therapies are declining. As well as, the rates and door-to treatment times for thrombolysis and thrombectomy therapies are increasing. The stroke units are being reallocated to serve COVID-19 patients, and stroke teams are being redeployed to COVID-19 centers.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2020 Category: Neurology Authors: Amal Al Hashmi, Atilla Ozcan Ozdemir, Ashfaq Shuaib, Hosam AlJehani, Ossama Mansour, Adel Alhazzani, Farid Aladhem, Mehdi Farhoudi, Seby John, Maher Saqqur Source Type: research

Clinician's Perception of Practice Changes for Stroke During the COVID-19 Pandemic
In this study, we investigated the changes in practices and policies related to stroke care through an online survey.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2020 Category: Neurology Authors: Hera A. Kamdar, Blake Senay, Shraddha Mainali, Vivien Lee, Deepak Kumar Gulati, Diana Greene-Chandos, Archana Hinduja, Tamara Strohm Source Type: research

Code Stroke patient referral by Emergency Medical Services during the public COVID-19 pandemic lockdown
During the coronavirus disease 2019 (COVID-19) pandemic the use of health care systems changed suddenly. Hospitals were overwhelmed as a result of the staggering COVID-19 patient numbers1 and/or modified their daily routine due to prophylactic allocation of resources.2 Public lockdowns with strict containment recommendations for the community have been announced around the world.3 Emergency Medical Services (EMS) and dispatch centers were confronted with increasing numbers of patients/calls and reorganization of the dispatch system including Code Stroke patient referral.
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2020 Category: Neurology Authors: Benno Ikenberg, Bernhard Hemmer, Michael Dommasch, Karl-Georg Kanz, Silke Wunderlich, Benjamin Knier Source Type: research

Acute Stroke as the Presenting Symptom of SARS-CoV-2 Infection in a Young Patient with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Coronavirus disease of 2019 (COVID-19) has currently reached pandemic levels and neurological manifestations, including stroke as the initial presentation, have been increasingly recognized (1-3). Majority of the reported ischemic strokes are large vessel occlusion or embolic appearing strokes and are frequently described in critically ill patients with severe COVID-19 disease (2), but small ischemic strokes have also been reported (4). Recently, stroke as the presenting symptom in younger patients (
Source: Journal of Stroke and Cerebrovascular Diseases - July 18, 2020 Category: Neurology Authors: Gabriela Trifan, Maureen Hillmann, Fernando D. Testai Source Type: research

Collateral damage – Impact of a pandemic on stroke emergency services
The COVID-19 pandemic's impact on stroke care is two-fold direct impact of the infection and indirect impact on non-COVID-19 diseases. Anecdotal evidence and clinical observation suggest that there is a decrease in the number of patients presenting with stroke during the pandemic. We aim to understand the impact of the COVID-19 pandemic on the utilization of stroke emergency services on a single comprehensive stroke center (CSC).
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Shashvat M. Desai, Francis X. Guyette, Christian Martin-Gill, Ashutosh P. Jadhav Source Type: research

Effect of COVID-19 Pandemic on Mechanical Thrombectomy for Acute Ischemic Stroke Treatment in United States
There is accumulating data suggesting that the ischemic stroke may be increased in patients with corona virus disease 2019 (COVID-19) due to hyper coagulopathy1,2. An increase in acute ischemic stroke patients who require mechanical thrombectomy is to be expected particularly in regions with high rates of COVID-191.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2020 Category: Neurology Authors: Adnan Qureshi, Farhan Siddiq, Brandi French, Camilo Gomez, Vishal Jani, Ameer Hassan, Muhammad Fareed Suri Source Type: research

Acute Stroke Care in a New York City Comprehensive Stroke Center during the COVID-19 Pandemic
The coronavirus disease-2019 (COVID-19) pandemic caused unprecedented demand and burden on emergency health care services in New York City. We aim to describe our experience providing acute stroke care at a comprehensive stroke center (CSC) and the impact of the pandemic on the quality of care for patients presenting with acute ischemic stroke (AIS).
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2020 Category: Neurology Authors: Shashank Agarwal, Erica Scher, Nirmala Rossan-Raghunath, Dilshad Marolia, Mariya Butnar, Jose Torres, Cen Zhang, Sun Kim, Matthew Sanger, Kelley Humbert, Omar Tanweer, Maksim Shapiro, Eytan Raz, Erez Nossek, Peter K. Nelson, Howard A. Riina, Adam de Haven Source Type: research

Universal laboratory testing for SARS-CoV-2 in hyperacute stroke during the COVID-19 pandemic
The coronavirus disease 2019 (COVID-19) pandemic necessitates organizational and structural adjustments to local health care systems to protect medical professionals and patients from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1). Particularly older individuals and those with cardiovascular comorbidities are thought to be at increased risk of COVID-19 (2). Consequently, stroke patients can be considered an at-risk population and might benefit from infection control screens at hospital entry (3,4).
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2020 Category: Neurology Authors: Kristian Barlinn, Timo Siepmann, Lars-Peder Pallesen, Simon Winzer, Annahita Sedghi, Percy Schroettner, Kristina Hochauf-Stange, Alexandra Prakapenia, Haidar Moustafa, Katja de With, Jennifer Linn, Heinz Reichmann, Jessica Barlinn, Volker Puetz Tags: Original Article Source Type: research

Stroke and COVID19: not only a large-vessel disease
Recent evidence has underlined the association between large-vessel stroke and COVID-19, probably due to a proinflammatory and prothrombotic microenvironment induced by SARS-CoV-2. Here, we report the case of a young fit woman affected by COVID-19 without any flu-like symptom, who suffered from speech disorder and left hemiparesis. Brain magnetic resonance evidenced two small acute brain infarctions in right perirolandic cortex without signs of previous ischemic lesions and hemorrhagic infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2020 Category: Neurology Authors: Giovanni Frisullo, Simone Bellavia, Irene Scala, Carla Piano, Roberta Morosetti, Valerio Brunetti, Paolo Calabresi, Giacomo Della Marca Tags: Case Report Source Type: research

Impact on rehabilitation programs during Covid-19 containment for children with pediatric and perinatal stroke.
PMID: 32519529 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 8, 2020 Category: Rehabilitation Authors: Bertamino M, Cornaglia S, Zanetti A, Di Rocco A, Ronchetti A, Signa S, Severino M, Moretti P, "Gaslini Stroke Study Group" Tags: Eur J Phys Rehabil Med Source Type: research

Hemorrhagic Stroke in Setting of Severe COVID-19 Infection Requiring Extracorporeal Membrane Oxygenation (ECMO)
To highlight the increased risk of hemorrhagic stroke secondary to postulated COVID-19 mediated vasculopathy with concomitant ECMO related bleeding complications.
Source: Journal of Stroke and Cerebrovascular Diseases - June 5, 2020 Category: Neurology Authors: Muhammad J. Zahid, Anam Baig, Nestor Galvez-Jimenez, Nydia Martinez Tags: Case Report Source Type: research

A protocol for acute stroke unit care during the COVID-19 pandemic
Limited resources, manpower shortages, tight infection control, physical distancing regulations and stay-at-home policies, we are all adapting our systems to care for stroke patients during this challenging time. There are different phases in the care of stroke patients and these may overlap; hyperacute care often involving reperfusion treatments, acute stroke unit (ASU) management as an inpatient and subsequently rehabilitation focus in an inpatient or outpatient setting. There have been reports providing guidance and protocols for hyperacute reperfusion treatment provision such as the management of stroke activations, co...
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2020 Category: Neurology Authors: Deidre Anne De Silva, Tan Il Fan, Shamala D/O Thilarajah Tags: Original Article Source Type: research

MRI Shows Pediatric Stroke Case Associated with COVID-19
Iranian researchers diagnosed ischemic stroke in COVID-19-positive child with no other symptoms.
Source: Diagnostic Imaging - June 3, 2020 Category: Radiology Authors: Whitney J. Palmer Tags: Brain MRI Infectious Diseases & Conditions/COVID-19 Ischemic stroke Pediatric Imaging Source Type: news

Hemorrhagic stroke and anticoagulation in COVID-19
We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Siddhant Dogra, Rajan Jain, Meng Cao, Seda Bilaloglu, David Zagzag, Sarah Hochman, Ariane Lewis, Kara Melmed, Katherine Hochman, Leora Horwitz, Steven Galetta, Jeffrey Berger Tags: Hemorrhagic stroke in COVID-19 Source Type: research

Unprotected stroke management in an undiagnosed case of Severe Acute Respiratory Syndrome Coronavirus 2 infection
We report the case of a 79-year-old woman, who was admitted for a wake-up stroke due to occlusion of the left middle cerebral artery. She was treated outside the COVID-19-dedicated track of the hospital because she had no concomitant signs or symptoms suggestive of SARS-CoV-2 infection nor recent contact with other infected individuals.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Claudia Papi, Gregorio Spagni, Andrea Alexandre, Paolo Calabresi, Giacomo Della Marca, Aldobrando Broccolini Source Type: research

Optimization of Resources and Modifications in Acute Ischemic Stroke Care in Response to the Global COVID-19 Pandemic
Background: The COVID-19 pandemic has presented unprecedented challenges to healthcare organizations worldwide. A steadily rising number of patients requiring intensive care, a large proportion from racial and ethnic minorities, demands creative solutions to provide high-quality care while ensuring healthcare worker safety in the face of limited resources. Boston Medical Center has been particularly affected due to the underserved patient population we care for and the increased risk of ischemic stroke in patients with COVID-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Thomas Ford, Gioacchino Curiale, Thanh N Nguyen, Hugo Aparicio, Emily K. Hamlyn, Suhas Gangadhara, Anna M Cervantes-Arslanian, David Greer, Jose Rafael Romero, Julie G Shulman Source Type: research

Acute Stroke Predicts Negative Outcome in COVID-19 Patients with Neuroimaging Findings
Half of patients hospitalized who have neurological findings for acute stroke could die.
Source: Diagnostic Imaging - May 22, 2020 Category: Radiology Authors: Whitney J. Palmer Tags: Brain MRI Infectious Diseases & Conditions/COVID-19 Ischemic stroke Source Type: news

COVID-19-Related Stroke
AbstractThe COVID-19 pandemic is associated with neurological symptoms and complications including stroke. There is hypercoagulability associated with COVID-19 that is likely a “sepsis-induced coagulopathy” and may predispose to stroke. The SARS-CoV-2 virus binds to angiotensin-converting enzyme 2 (ACE2) present on brain endothelial and smooth muscle cells. ACE2 is a key part of the renin angiotensin system (RAS) and a counterbalance to angiotensin-converting enzyme 1 (ACE1) and angiotensin II. Angiotensin II is proinflammatory, is vasoconstrictive, and promotes organ damage. Depletion of ACE2 by SARS-CoV-2 may tip the...
Source: Translational Stroke Research - May 6, 2020 Category: Neurology Source Type: research

A Stroke Care Model at an Academic, Comprehensive Stroke Center During the 2020 COVID-19 Pandemic
The COVID-19 pandemic has required the adaptation of hyperacute stroke care (including stroke code pathways) and hospital stroke management. There remains a need to provide rapid and comprehensive assessment to acute stroke patients while reducing the risk of COVID-19 exposure, protecting healthcare providers, and preserving personal protective equipment (PPE) supplies. While the COVID infection is typically not a primary cerebrovascular condition, the downstream effects of this pandemic force adjustments to stroke care pathways to maintain optimal stroke patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2020 Category: Neurology Authors: Dawn Meyer, Brett C. Meyer, Karen S. Rapp, Royya Modir, Kunal Agrawal, Lovella Hailey, Melissa Mortin, Richard Lane, Tamra Ranasinghe, Brian Sorace, Tara D. von Kleist, Emily Perrinez, Mohammed Nabulsi, Thomas Hemmen Source Type: research

Stroke priorities during COVID-19 outbreak: acting both fast and safe
While the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spreads all over the world, the healthcare systems are facing the dramatic challenge of simultaneously fight against the outbreak and life-threating emergencies.In this biological setting, emergency departments and neurovascular teams are exposed to high risk of infection and should therefore be prepared to deal with neurological emergencies safely.The purpose of this article is to analyze the current evidence on COVID-19 in the context of acute ischemic stroke and to describe the model of behavior we are putting into action to maintain the stroke pathw...
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2020 Category: Neurology Authors: Alessandro Pedicelli, Iacopo Valente, Fabio Pilato, Marisa Distefano, Cesare Colosimo Source Type: research

Acute Stroke Care in the Coronavirus Disease 2019 Pandemic
Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease with serious public health risk, and has taken the world off guard with its rapid spread. As the COVID-19 pandemic intensifies, overwhelming the healthcare system and the medical community, current practice for the management of acute ischemic stroke (AIS) will require modification, and guidelines should be relaxed while maintaining high standard quality of care. The aim of these suggestions is to avoid contributing to the rapid spread of COVID-19 as well as to conserve what are likely to be very limited resources (including personnel, intensive care/hos...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Rima M Dafer, Nicholas D Osteraas, Jose Biller MD Source Type: research