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The effect of gender and genetic polymorphisms on matrix metalloprotease (MMP) and tissue inhibitor (TIMP) plasma levels in different infectious and non‐infectious conditions
In conclusion, male gender and MMP‐3(‐1612 5A/6A) 6A allele carriage increased MMP‐3 plasma levels significantly, especially in patients with severe bacterial sepsis. This confounding gender effect needs to be addressed when evaluating MMP‐3 plasma levels in any infectious or non‐infectious condition.
Source: Clinical and Experimental Immunology - September 11, 2015 Category: Allergy & Immunology Authors: J. Collazos, V. Asensi, G. Martin, A. H. Montes, T. Suárez‐Zarracina, E. Valle‐Garay Tags: Original Article Source Type: research