Query: stroke

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Infectious Disease: Chlamydia

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Total 10 results found since Jan 2013.

Cross-Reactivity as a Mechanism Linking Infections to Stroke
The relevance of infections as risk factor for cerebrovascular disease is being increasingly recognized. Nonetheless, the pathogenic link between the two entities remains poorly understood. Consistent with recent advances in medicine, the present work addresses the hypothesis that infection-induced immune responses may affect human proteins associated with stroke. Applying established procedures in bioinformatics, the pathogen antigens and the human proteins were searched for common sequences using pentapeptides as probes. The data reported demonstrate massive peptide sharing between infectious pathogens—such as Chlamydi...
Source: Frontiers in Neurology - May 14, 2019 Category: Neurology Source Type: research

Psychosis Polyrisk Score (PPS) for the Detection of Individuals At-Risk and the Prediction of Their Outcomes
Conclusions The combination of risk/protective factors encompassing genetic (PRS) and non-genetic information (PPS) holds promise for overcoming the epidemiological weakness of the CHR-P paradigm. The PPS conceptually and empirically developed here will facilitate future research in this field and hopefully advance our ability to detect individuals at-risk for psychosis and forecast their clinical outcomes. Ethics Statement This study was supported by the King's College London Confidence in Concept award from the Medical Research Council (MRC) (MC_PC_16048) to PF-P. This study also represents independent researc...
Source: Frontiers in Psychiatry - April 17, 2019 Category: Psychiatry Source Type: research

Pivotal pathogenic and biomarker role of Chlamydia Pneumoniae in neurovascular diseases.
Abstract Chlamydia pneumoniae(C.Pn) is an obligatory intracellular bacterium that is associated with respiratory tract infections like pneumonia, pharyngitis and bronchitis. It has also been implicated in cerebrovascular (stroke) as well as cardiovascular diseases. The most possible pathway via which C.Pn elicits its pathogenesis could be via activation of human vascular smooth muscle cells (VSMCs) proliferation resulting in the stimulation of toll like receptor-4 (TLR-4) and/or phospho-44/42(p44/p42) mitogen-activated protein kinases (MAPK). It is also established that tyrosine phosphorylation of IQ domain GTPase...
Source: Current Neurovascular Research - July 17, 2018 Category: Neurology Authors: Richard SA Tags: Curr Neurovasc Res Source Type: research

A True Hematologic Emergency
​BY GREGORY TAYLOR, DO, & JACKLYN M​CPARLANE, DO​A 33-year-old woman with a past medical history of sickle cell SS presented to the emergency department with chest pain, difficulty breathing, and a cough for two days. Her chest pain was diffuse, without radiation, and partially reproducible. Her cough was nonproductive, and she also reported fever and chills.The patient noted this was different from her normal back and leg pain from past sickle cell crises. She was following up with a sickle cell specialist, and was compliant with her hydroxyurea treatment.Her temperature was 102.8°F, blood pressure was 94/60 mm...
Source: The Case Files - June 26, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Infections and Chlamydia pneumoniae antibodies influence the functional outcome in thrombolysed strokes
Thrombolysis is effective in ischemic stroke patients, but some factors influence its benefit. Previous infections could increase the risk of ischemic stroke by an activation of systemic inflammation. We analysed the influence of previous infections and Chlamydia pneumoniae serology on functional outcome in thrombolysed stroke patients. Methods: Consecutive thrombolysed stroke patients admitted during calendar year 2011 were analysed. Demographics, vascular risk factors, clinical and aetiological data were registered.
Source: Journal of the Neurological Sciences - August 2, 2017 Category: Neurology Authors: Domenico Consoli, Simone Vidale, Marco Arnaboldi, Anna Cavallini, Arturo Consoli, Franco Galati, Donata Guidetti, Giuseppe Micieli, Maurizia Rasura, Roberto Sterzi, Danilo Toni, Domenico Inzitari Source Type: research

Carotid intima media thickness and blood biomarkers of atherosclerosis in patients after stroke or myocardial infarction.
CONCLUSIONS: Our study supports linear correlations between CIMT and IC and hs-CRP levels. However, these associations seem to depend on the type of vascular burden. PMID: 28051279 [PubMed - in process]
Source: Croatian Medical Journal - December 31, 2016 Category: Journals (General) Authors: Kurkowska-Jastrzebska I, Karlinski MA, Błazejewska-Hyzorek B, Sarzynska-Dlugosz I, Filipiak KJ, Czlonkowska A Tags: Croat Med J Source Type: research

Infectious Burden and Cognitive Decline in the Northern Manhattan Study
ConclusionA quantitative stroke risk‐weighted measure of IB explained variability in baseline executive function performance and associated with decline in memory. Past exposure to common infections may contribute to vascular cognitive impairment and warrants further study.
Source: Journal of the American Geriatrics Society - August 20, 2015 Category: Geriatrics Authors: Clinton B. Wright, Hannah Gardener, Chuanhui Dong, Mitsuhiro Yoshita, Charles DeCarli, Ralph L. Sacco, Yaakov Stern, Mitchell S. V. Elkind Tags: Clinical Investigations Source Type: research

CDC National Health Report: Leading Causes of Morbidity and Mortality and Associated Behavioral Risk and Protective Factors-United States, 2005-2013.
This report reviews population health in the United States and provides an assessment of recent progress in meeting high-priority health objectives. The health status indicators described in this report were selected because of their direct relation to the leading causes of death and other substantial sources of morbidity and mortality and should be the focus of prevention efforts. REPORTING PERIOD COVERED: Data are reported starting in 2005 (or the earliest available year since 2005) through the current data year. Because data sources and specific indicators vary regarding when data are available, the most recent yea...
Source: MMWR Surveill Summ - October 31, 2014 Category: Epidemiology Authors: Johnson NB, Hayes LD, Brown K, Hoo EC, Ethier KA Tags: MMWR Surveill Summ Source Type: research

Novel Inflammatory Biomarkers and Their Correlation to Chlamydia pneumoniae Titres in Acute Ischemic Stroke
Conclusions: The study demonstrated high levels of hsp 65 and neopterin levels in AIS correlated to significantly elevated IgA titres of C pneumoniae. Elevated levels of hsp 65 were associated with stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2014 Category: Neurology Authors: M.V. Padma Srivastava, Ashu Bhasin, Rama Chaudhry, Sakshi Sharma, Vivekanandhan Subbaiah, Rohit Bhatia, Manjari Tripathi Tags: Original Articles Source Type: research

NICE: 'schools should provide morning-after pill'
Conclusion Everyone makes mistakes, but if you find yourself relying on the morning-after pill as a regular method of contraception, you may want to speak to a healthcare professional about what would be the most suitable form of ongoing contraception for you to use. This could include methods that do not involve needing to take a daily pill, such as contraceptive patches, injections or an implant. However, none of these methods will protect you against sexually transmitted infections (STIs). Condoms are cheap, free of side effects and they will protect you against STIs such as chlamydia. For more information about your ...
Source: NHS News Feed - March 26, 2014 Category: Consumer Health News Tags: QA articles Pregnancy/child Source Type: news