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Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 11, 2019 Category: Radiology Source Type: research

Study: Long-term antibiotic use among women linked to increased risk of heart attack and stroke
(Natural News) When you think about what can go wrong when you take antibiotics, there are two major complications that likely come to mind: that all-too-familiar stomach upset and the more big-picture issue of antibiotic resistance and superbugs. However, there’s another potential problem that you might not associate with antibiotic use: a higher risk of...
Source: NaturalNews.com - October 5, 2019 Category: Consumer Health News Source Type: news

Safety and effectiveness of CATCH+ as a first-line device for revascularization in the treatment of acute ischemic stroke
Conclusions: The CATCH+ device is a safe and effective mechanical thrombectomy device for the first-line treatment of acute ischemic stroke.
Source: Journal of Neuroradiology - September 18, 2019 Category: Radiology Source Type: research

Efficacy of ADAPT with large-bore reperfusion catheter in anterior circulation acute ischemic stroke: a multicentric Italian experience
ConclusionsADAPT is a valid technique with respect to the rates of TICI 2b/3 recanalization and 90-day mRS scores. In this series, an attempt at recanalization with ADAPT with larger-bore reperfusion catheter may be warranted prior to stentriever thrombectomy.
Source: La Radiologia Medica - August 31, 2019 Category: Radiology Source Type: research

Decompressive craniectomy in malignant middle cerebral artery infarction: family perception, outcome and prognostic factors.
CONCLUSIONS: We present a 21 patients group where the best outcome was achieved in patients ≤60 years old. The severe neurological sequelae in patients with malignant infarction subjected to decompressive hemicraniectomy are tolerated and accepted by most families to the benefit of survival. We must not let this family satisfaction hide the prognosis, having to contextualize it within the real ambulatory situation of the patients. PMID: 31445797 [PubMed - as supplied by publisher]
Source: Neurocirugia - August 21, 2019 Category: Neurosurgery Authors: García-Feijoo P, Isla A, Díez-Tejedor E, Mansilla B, Palpan Flores A, Sáez-Alegre M, Vivancos C Tags: Neurocirugia (Astur) Source Type: research

Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke
Conclusion: Total SVD burden negatively associated with functional outcome at 3 months in patients with acute ischemic stroke and is superior to individual SVD feature in prediction of functional outcome. MRI-based assessment of total SVD burden is highly valuable in clinical management of stroke victims, and could help guide the allocation of resources to improve outcome.
Source: Frontiers in Neurology - August 6, 2019 Category: Neurology Source Type: research

Prolonged Heightened Blood Pressure Following Mechanical Thrombectomy for Acute Stroke is Associated with Worse Outcomes
ConclusionHigh daily maximum SBP and a rebound SBP on the third day following MT is independently associated with increased likelihood of functional dependence.
Source: Neurocritical Care - August 5, 2019 Category: Neurology Source Type: research

“A contemporary description of staphylococcus aureus prosthetic valve endocarditis. Differences according to the time elapsed from surgery”
Staphylococcus aureus prosthetic valve endocarditis (SAPVE) has a poor prognosis. There are no large series that accurately describe this entity. This is a retrospective observational study on a prospective cohort from 3 Spanish reference hospitals for cardiac surgery, including 78 definitive episodes of left SAPVE between 1996 and 2016. Fifty percent had a Charlson Index score>5; 53% were health care-related. Twenty percent did not present fever. Complications at diagnosis included: severe heart failure (HF, 29%), septic shock (SS, 17.9%), central nervous system abnormalities (19%), septic metastasis (4%). Hemorrhagic s...
Source: Medicine - August 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Number of Stentriever Passes and Outcome after Thrombectomy in Stroke
Conclusions:The number of passes needed to achieve target vessel recanalization modifies outcome after thrombectomy and successful recanalization after a single pass is associated with favorable outcome.
Source: Journal of Neuroradiology - April 12, 2019 Category: Radiology Source Type: research

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke
ConclusionsEarly CBF response to mild HOB elevation in the ipsilesional hemisphere is related to functional outcome. Further studies may enable optical monitoring at the bedside to individualize management strategies in the early phase of AIS.
Source: Journal of Neurology - February 9, 2019 Category: Neurology Source Type: research

Safety of urgent endarterectomy in acute non ‐disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study
ConclusionsOur findings highlight that urgent CEA performed within two days from the index event is related to a non ‐significant increase in the risk of peri‐procedural stroke. The safety of urgent CEA requires further evaluation in larger datasets.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Andromachi Roussopoulou, Georgios Tsivgoulis, Christos Krogias, Andreas Lazaris, Konstantinos Moulakakis, George S. Georgiadis, Robert Mikulik, John D. Kakisis, Christina Zompola, Simon Faissner, Maria Chondrogianni, Chrissoula Liantinioti, Th Tags: Original Article Source Type: research

Quantitative EEG and functional outcome following acute ischemic stroke.
CONCLUSIONS: DTAABR and alpha RP are the best qEEG indices and superior to ASPECTS in post-stroke outcome prediction. They improve the discriminative capacity of already known clinical and imaging stroke outcome predictors, both at discharge and 12 months after stroke. SIGNIFICANCE: qEEG indices are independent predictors of stroke outcome. PMID: 29935475 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - June 18, 2018 Category: Neurology Authors: Bentes C, Peralta AR, Viana P, Martins H, Morgado C, Casimiro C, Franco AC, Fonseca AC, Geraldes R, Canhão P, Pinho E Melo T, Paiva T, Ferro JM Tags: Clin Neurophysiol Source Type: research

Results and functional outcomes of acute ischemic stroke patients who underwent mechanical thrombectomy admitted to intensive care unit
Conclusions The factors relating to a worse functional outcome were symptomatic hemorrhage transformation, lack of recanalization and complications during EVT. The factors relating to mortality were symptomatic hemorrhage and hydrocephalus. Distal flow was achieve in most cases with a low complication rate. Half of the patients presented functional independence one year after the stroke.
Source: Medicina Intensiva - May 30, 2018 Category: Intensive Care Source Type: research

Real-world treatment of large vessel occlusions: combined outcomes of directly presenting and transferred-in patients to a stroke center.
Conclusion High rates of favorable angiographic and clinical outcomes were found among AIS patients receiving ET in our single-center experience, particularly among transferred in patients. The establishment of a stroke network may help in the efficient transfer and assembly of appropriate resources for eligible patients that are transferred in for ET. PMID: 29683786 [PubMed - as supplied by publisher]
Source: Neurological Research - April 25, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Sex as predictor for achieved health outcomes and received care in ischemic stroke and intracerebral hemorrhage: a register-based study
ConclusionsA lower proportion of women had good functioning, a difference that remained in IS after adjustments for age, socioeconomic factors, living arrangements, ADL dependency, and stroke severity. The amount of received hospital care was lower for women after adjustments. Whether shorter hospital stay results in lower function or is a consequence of lower function cannot be elucidated. One-year survival was higher in men when no adjustments were made but lower after adjustments. This likely reflects that women were older at time of stroke, had more severe strokes, and more disability pre-stroke —factors that make a ...
Source: Biology of Sex Differences - March 7, 2018 Category: Biology Source Type: research

Predictors of favorable outcome after mechanical thrombectomy for anterior circulation acute ischemic stroke in octogenarians
Conclusions There is no reason to withhold mechanical thrombectomy on the basis of age alone. Small infarct core, low NIHSS, male gender and use of IVT are associated with a better functional outcome.
Source: Journal of Neuroradiology - February 24, 2018 Category: Radiology Source Type: research

Clinical outcomes of acute ischemic stroke patients treated by direct catheter-based trombectomy depending on their baseline characteristics
Conclusions Mechanical thrombectomy achieved better clinical results in younger patients, in smokers and in patients with stroke not caused by atrial fibrillation.
Source: Cor et Vasa - January 30, 2018 Category: Cardiology Source Type: research

Antibiotic therapy for preventing infections in people with acute stroke.
CONCLUSIONS: Preventive antibiotics had no effect on functional outcome or mortality, but significantly reduced the risk of 'overall' infections. This reduction was driven mainly by prevention of urinary tract infection; no effect for pneumonia was found. PMID: 29355906 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 22, 2018 Category: General Medicine Authors: Vermeij JD, Westendorp WF, Dippel DW, van de Beek D, Nederkoorn PJ Tags: Cochrane Database Syst Rev Source Type: research

Increase in Neutrophil after r ‐tPA Thrombolysis Predicts Poor Functional Outcome of Ischemic Stroke: A Longitudinal Study
ConclusionsDynamic increase in neutrophil after stroke significantly predicts 3‐month death or major disability in acute ischemic stroke patients receiving r‐tPA treatment.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - January 1, 2018 Category: Neurology Authors: Jijun Shi, Hao Peng, Shoujiang You, Yuanyuan Liu, Jiaping Xu, Yingying Xu, Huihui Liu, Rongfang Shi, Yongjun Cao, Chun ‐Feng Liu Tags: Original Article Source Type: research

Codeine is associated with poor prognosis in acute stroke
ConclusionUse of codeine‐containing analgesics is associated with a poorer short‐term prognosis and an increased occurrence of complications in the acute phase after a stroke. The highly significant findings suggest that codeine has a negative effect on acute stroke patients. The study reflects exploratory analyses and prospective studies are necessary to determine the background of the association observed in our study. Use of codeine‐containing analgesics is associated with a poorer short‐term prognosis and an increased occurrence of complications in the acute phase after a stroke. The highly significant finding...
Source: Brain and Behavior - November 19, 2017 Category: Neurology Authors: Stian T. Ryste, Bernt A. Engelsen, Halvor Naess Tags: ORIGINAL RESEARCH Source Type: research

Mechanical Thrombectomy with Solitaire Stent Retrieval for Acute Cardioembolic Stroke.
Conclusion: Some cases of cardioembolic stroke are resistant to MTSR and may need other treatment modalities. Careful interpretation of angiogram may be helpful to the decision. PMID: 29142621 [PubMed]
Source: Journal of Korean Neurosurgical Society - November 18, 2017 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Iatrogenic Vessel Dissection in Endovascular Treatment of Acute Ischemic Stroke
ConclusionThe occurrence of ID is a  rare complication of endovascular AIS treatment associated with smoking and mechanical thrombectomy.
Source: Clinical Neuroradiology - November 2, 2017 Category: Neurology Source Type: research

Factors Mediating Outcome After Stroke: Gender, Thrombolysis, and Their Interaction
AbstractSeveral studies, but not all, have shown that women benefit more from intravenous thrombolysis than men; few have accounted for pre-stroke mobility. Our aim was to determine whether there was an interaction between gender and thrombolysis treatment in 3-month modified Rankin Scale (mRS) score, after adjusting for pre-stroke mobility. We retrospectively reviewed medical records of 1390 consecutive ischemic stroke patients admitted between October 2012 and July 2015. The 3-month mRS was obtained from clinic visits. Thrombolysis-by-gender interaction was evaluated in univariate and multivariate analyses using ordinal ...
Source: Translational Stroke Research - October 24, 2017 Category: Neurology Source Type: research

Stereotactic Catheter Ventriculocisternostomy for Clearance of Subarachnoid Hemorrhage Clinical Sciences
Conclusions—STX-VCS was feasible and safe in patients with severe aneurysmal subarachnoid hemorrhage. Initial results indicate that DCI and mortality can be reduced, and neurological outcome may be improved with this method.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Roland Roelz, Volker A. Coenen, Christian Scheiwe, Wolf-Dirk Niesen, Karl Egger, Istvan Csok, Rainer Kraeutle, Ramazan Jabbarli, Horst Urbach, Peter C. Reinacher Tags: Cerebral Aneurysm, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Transfer of stroke patients impairs eligibility for endovascular stroke treatment
Conclusions EST should be provided directly whenever possible as one in four transferred stroke patients becomes ineligible for EST during transfer. If direct transfer is not possible, indication for EST should be re-assessed after transfer.
Source: Journal of Neuroradiology - September 19, 2017 Category: Radiology Source Type: research

Intravenous thrombolysis for patients with in ‐hospital stroke onset: propensity‐matched analysis from the SITS‐EAST registry
ConclusionsOur findings underline the safety and efficacy of IVT for IHS. They also underscore the potential of reducing in‐hospital delays for timely tPA delivery in patients with IHS.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - September 9, 2017 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Pavla Kadlecov á, Anna Czlonkowska, Adam Kobayashi, Miroslav Brozman, Viktor Švigelj, Laszlo Csiba, Klara Fekete, Janika Kõrv, Vida Demarin, Aleksandras Vilionskis, Dalius Jatuzis, Yakup Krespi, Theodore Kar Tags: Original Article Source Type: research

Morning Rounds: Colon cancer deaths, stroke rates among women
Dr. Tara Narula joins "CBS This Morning: Saturday" to discuss a surprising and concerning rise in colon cancer death rates among younger Americans, a new study that shows stroke rates are going down for men but not women and a new development in the on-going battle with antibiotic-resistant bacteria.
Source: Health News: CBSNews.com - August 12, 2017 Category: Consumer Health News Source Type: news

Evaluation of functional outcome measured by modified Rankin scale in rtPA treated patients with acute ischemic stroke.
Authors: Georgievski-Brkic B, Savic M, Nikolic D, Nikcevic L, Vukicevic M, Kozic D Abstract Aim of our study was to assess functional outcome measured by modified Rankin scale (mRS) in patients that were treated with thrombolytic therapy-recombinant tissue plasminogen activator (rtPA) after acute ischemic stroke. The study included 100 participants that were treated after acute ischemic stroke. Analyzed parameters included: gender; age groups: age 54 and below (Groupup to-54), 55-64 (Group55-64), 65-74 (Group65-74), and 75 and above (Group75-up); cerebral blood flow (CBF) and cerebral blood volume (CBV). Considerin...
Source: Archives Italiennes de Biologie - March 23, 2017 Category: Neuroscience Tags: Arch Ital Biol Source Type: research

Endovascular thrombectomy and medical therapy versus medical therapy alone in acute stroke: A randomized care trial
Conclusion A care trial was implemented to offer verifiable care to acute stroke patients. This approach offers a promising means to manage clinical dilemmas and guide uncertain practices.
Source: Journal of Neuroradiology - February 25, 2017 Category: Radiology Source Type: research

Impacts of Cigarette Smoking and Basilar Artery Flow on 1-year Recovery in 3-Month survivors of Intracranial Vertebrobasilar Artery Dissection-related Ischemic Stroke.
CONCLUSIONS: Our results suggest that adequate blood flow may be key to functional recovery after iVBDcaused PCS. Methods to improve blood flow and tissue perfusion after iVBD-caused PCS should be considered in the future clinical studies with the purpose to improve functional recovery in these patients. PMID: 27854084 [PubMed - in process]
Source: Acta Neurologica Taiwanica - November 19, 2016 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

The relationship of platelet-to-lymphocyte ratio with clinical outcome and final infarct core in acute ischemic stroke patients who have undergone endovascular therapy.
In this study we aimed to evaluate whether the PLR had a prognostic role in stroke patients undergoing thrombectomy and attempted to determine the effect that this ratio had on their survival. METHODS: Over a three-year period, demographic, clinical, and angiographic findings of 57 consecutive patients with acute ischemic stroke who underwent mechanical thrombectomy were evaluated. RESULTS: The patients were divided into two groups on the basis of a PLR level cut-off value of 145 based on receiver operating characteristic (ROC) curve. Successful revascularization (mTICI 2b and 3) was achieved in 42 of 57 (73.7%) pa...
Source: Neurological Research - August 3, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Association between Leukoaraiosis and Poor Outcome is not due to Reperfusion Inefficiency after Intravenous Thrombolysis
Abstract Leukoaraiosis (LA) is associated with structural and functional cerebrovascular impairment, which may compromise the capacity of ischemic tissue to maximize reperfusion after intravenous thrombolysis (IVT). We aimed to determine whether severe LA is correlated with reperfusion inefficiency, which contributes to infarct growth and poor functional outcome. We analyzed data from our consecutive acute ischemic stroke (AIS) patients who had acquired baseline and 24-h follow-up diffusion- and perfusion-weighted imaging. Reperfusion was defined as reduction of ≥70 % of hypoperfusion lesion at 24 h from basel...
Source: Translational Stroke Research - June 2, 2016 Category: Neurology Source Type: research

Effective management of patients with acute ischemic stroke based on lean production on thrombolytic flow optimization
In this study, we aimed to determine whether applying lean principles to flow optimization could hasten the initiation of thrombolysis. A multidisciplinary team (Stroke Team) was organized to implement an ongoing, continuous loop of lean production that contained the following steps: decomposition, recognition, intervention, reengineering and assessment. The door-to-needle time (DNT) and the percentage of patients with DNT ≤ 60 min before and after the adoption of lean principles were used to evaluate the efficiency of our flow optimization. Thirteen patients with AIS in the pre-lean period and 43 patients with AIS in...
Source: Australasian Physical and Engineering Sciences in Medicine - April 19, 2016 Category: Biomedical Engineering Source Type: research

Women have a poorer very long-term functional outcome after stroke among adults aged 18–50 years: the FUTURE study
In conclusion, 14 years after an ischemic cerebrovascular event in young adults, one out of five IS survivors and one out of ten TIA survivors is still dependent in daily life, with a two to threefold higher risk of a poor outcome in women. This includes a period of life, during which important decisions regarding work and family life have to be made.
Source: Journal of Neurology - April 2, 2016 Category: Neurology Source Type: research

The stroke east Saxony pilot project for organized post‐stroke care: a case–control study
ConclusionsOur pilot data suggest that organized post‐stroke care enhances achievement of secondary prevention goals. Its possible effect on stroke recurrence, long‐term disability, and quality of life is currently investigated in a prospective cohort study. The Stroke East Saxony Pilot Project for Organized Post‐Stroke Care was case–control study to explore the feasibility of a self‐developed standardized post‐stroke pathway and its impact on secondary stroke prevention and long‐term outcome in patients with acute stroke. These pilot data suggest that organized post‐stroke care enhances achievement of sec...
Source: Brain and Behavior - April 1, 2016 Category: Neurology Authors: Ulf Bodechtel, Kristian Barlinn, Uwe Helbig, Katrin Arnold, Timo Siepmann, Lars‐Peder Pallesen, Volker Puetz, Heinz Reichmann, Jochen Schmitt, Jessica Kepplinger Tags: Original Research Source Type: research

Plasma miR-124-3p and miR-16 concentrations as prognostic markers in acute stroke.
CONCLUSIONS: Plasma miR-124-3p and miR-16 are molecular markers which could be useful for the early prediction of mortality and mRS. PMID: 26968104 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - March 9, 2016 Category: Biochemistry Authors: Rainer TH, Leung LY, Chan CP, Leung YK, Abrigo JM, Wang D, Graham CA Tags: Clin Biochem Source Type: research

First-line lesional aspiration in acute stroke thrombectomy using a novel intermediate catheter: Initial experiences with the SOFIA.
CONCLUSIONS: Lesional aspiration with SOFIA is in line with published data. The SOFIA may be used as a first-line device, aiming at fast recanalization by sole aspiration with good safety and efficacy. If unsuccessful, it converts into part of a stent retriever-based multimodality treatment. PMID: 26908589 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - February 26, 2016 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Severity and outcomes according to stroke etiology in patients under 50 years of age with ischemic stroke
Abstract To analyze the association of stroke etiological subtypes with severity and outcomes at 3 and 12 months in patients ≤50 years. Observational study of patients admitted to a stroke unit (2007–2013). Variables: demographic data, vascular risk factors, comorbidities, severity on admission (NIHSS), and good functional outcome (mRS ≤ 1) at 3 and 12 months. We used multivariate analyses to evaluate the influence of stroke etiology on severity and outcomes. We included 214 patients, 58.3 % men, mean age 41.4 years. General linear models showed all etiologies were more severe than lacunar strokes (P...
Source: Journal of Thrombosis and Thrombolysis - February 5, 2016 Category: Hematology Source Type: research

Stent-based thrombectomy versus intravenous tissue plasminogen activator in acute ischaemic stroke: A systematic review and meta-analysis.
CONCLUSION: Stentrievers can achieve a high rate of recanalisation and functional independence in acute ischaemic stroke and have a relatively good safety profile. Our meta-analysis demonstrates a clear benefit of an intra-arterial mechanical approach vs standard treatment. PMID: 26490828 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - October 23, 2015 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Healthcare circuits and functional outcomes 3 and 12 months after a stroke in a population-based cohort of 929 patients
In this study, carried out with an exhaustive population within a region and a one-year follow-up with few missing data, the results show a morbi-mortality after stroke higher than the one reported in previous studies. The results also confirm the better prognosis of IS.
Source: Annals of Physical and Rehabilitation Medicine - October 2, 2015 Category: Rehabilitation Source Type: research

Computed tomography perfusion-based thrombolysis in wake-up stroke
Abstract Wake-up stroke (WUS) patients are typically excluded from reperfusion treatment, as the time of symptoms onset is unknown. The purpose of this study is to evaluate the clinical outcome and safety of intravenous thrombolysis with rt-PA in patients with WUS eligible for therapy using computed tomography perfusion criteria (CTP), compared to patients treated with rt-PA within 4.5 h of symptoms onset (non-WUS). This is an experimental, open-label trial, controlled against the best therapy currently in use. Primary endpoints were functional independence after 3 months [modified Rankin scale (mRS) ≤ 1] ...
Source: Internal and Emergency Medicine - September 14, 2015 Category: Emergency Medicine Source Type: research

Thrombectomy assisted by carotid stenting in acute ischemic stroke management: benefits and harms
This study assesses the benefits and harms of thrombectomy assisted by carotid stenting and identifies factors associated with clinical outcome and procedural complications. Retrospective single-center analysis of 47 consecutive stroke patients with carotid occlusion or high-grade stenosis and concomitant intracranial embolus treated between September 2011 and December 2014. Benefits included early improvement of stroke severity (NIHSS ≥ 10) or complete remission within 72 h and favorable long-term outcome (mRS ≤ 2). Harms included complications during and following EVT. Mean age was 64.3 years (standard deviatio...
Source: Journal of Neurology - September 7, 2015 Category: Neurology Source Type: research

Influence of previous physical activity on the outcome of patients treated by thrombolytic therapy for stroke
Abstract Physical activity prevents stroke and is associated with less severe strokes. The neuroprotective effect in patients treated with intravenous (i.v.) recombinant tissue plasminogen activator (rt-PA), remains uncertain. We aimed at evaluating the relationship between previous physical activity and outcomes in stroke patients treated with i.v. rt-PA. OPHELIE-SPORT was a prospective observational multicenter study conducted in French and Japanese stroke patients treated with i.v. rt-PA. We evaluated the presence, weekly duration (<2, 2–5, >5 h) and intensity (light, moderate, heavy) of previous leisu...
Source: Journal of Neurology - August 14, 2015 Category: Neurology Source Type: research

Post‐stroke cognitive impairment is common even after successful clinical recovery
ConclusionsCognitive impairment as evaluated with a comprehensive neuropsychological assessment is prevalent in stroke survivors even with successful clinical recovery. Typically multiple domains and complex cognitive abilities are affected. MMSE is not sensitive in detecting these symptoms. Post‐stroke cognitive impairment is strongly related to poor functional outcome.
Source: European Journal of Neurology - June 4, 2015 Category: Neurology Authors: H. Jokinen, S. Melkas, R. Ylikoski, T. Pohjasvaara, M. Kaste, T. Erkinjuntti, M. Hietanen Tags: Original Article Source Type: research

Endovascular treatment of acute ischemic stroke - Own experience.
CONCLUSION: Studies suggest that endovascular techniques are effective and safe in the treatment of ischemic stroke. Greater efficiency is characterized by intraarterial thrombolysis. Patients who were treated endovascular improved significantly. PMID: 25890921 [PubMed - in process]
Source: Neurologia i Neurochirurgia Polska - April 25, 2015 Category: Neurology Authors: Knap D, Honkowicz M, Kirmes T, Koroński M, Bukański M, Kysiak M, Kadłubicki B, Dymon I, Sieroń D, Baron J Tags: Neurol Neurochir Pol Source Type: research

Anemia in young patients with ischaemic stroke
ConclusionAnemia on admission was associated with stroke in CeAD patients and with more severe strokes in both study samples. Moderate to severe anemia may predict unfavorable outcome.
Source: European Journal of Neurology - February 24, 2015 Category: Neurology Authors: L. Kellert, M. Kloss, A. Pezzini, T. M. Metso, A. J. Metso, S. Debette, D. Leys, V. Caso, V. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, H. Gensicke, P. A. Lyrer, J. Bösel, S. T. Engelter, C. Grond‐Ginsbach, Tags: Original Article Source Type: research

Acute Stroke and Obstruction of the Extracranial Carotid Artery Combined with Intracranial Tandem Occlusion: Results of Interventional Revascularization
Conclusion Endovascular recanalization of acute cervical carotid artery occlusion was technically feasible in all patients, and resulted in high extra- and intracranial revascularization rates. A trend for favorable clinical outcome was seen in a higher TICI score, younger age, good collateral status, and combined IV rTPA and endovascular therapy.
Source: CardioVascular and Interventional Radiology - December 30, 2014 Category: Radiology Source Type: research

Differences in wake‐up and unknown onset stroke examined in a stroke registry
ConclusionWUS has lower rates of ICH but similar stroke severity and outcomes to AOS. UOS prevalence appears to be increasing, with higher stroke severity and worse prognosis.
Source: International Journal of Stroke - October 1, 2014 Category: Neurology Authors: John M. Reid, Dingwei Dai, Bharath Cheripelli, Christine Christian, Yvette Reidy, Gord J. Gubitz, Stephen J. Phillips Tags: Research Source Type: research

Thrombolysis in patients with prior stroke within the last 3 months
ConclusionsIn patients with prior stroke within the last 3 months, none of the sICHs and only one asymptomatic intracerebral hemorrhage occurred in the region of the former infarct. The high mortality was influenced by four patients, who died until discharge due to acute major index stroke. It is reasonable to include these patients in randomized clinical trials and registries to assess further their thrombolysis benefit−risk ratio.
Source: European Journal of Neurology - July 17, 2014 Category: Neurology Authors: M. R. Heldner, H. P. Mattle, S. Jung, U. Fischer, J. Gralla, C. Zubler, M. El‐Koussy, G. Schroth, M. Arnold, M.‐L. Mono Tags: Original Article Source Type: research