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Infectious Disease: Helicobacter Pylori

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Total 29 results found since Jan 2013.

Combined Effect Of Helicobacter Pylori Infection And Elevated C-Reactive Protein On 3-Month Prognosis Of Ischemic Stroke
Background and Aims: To investigate the combined effect of Helicobacter pylori (HP) infection and elevated C-reactive protein (CRP) on the prognosis of acute ischemic stroke patients at 3 months.
Source: Atherosclerosis - August 3, 2019 Category: Cardiology Authors: T. Xu, C. Zhang, A. Wang, Y. Zhang Tags: E-poster session Source Type: research

Helicobacter pylori infection and prevalence of stroke
ConclusionsThe results support the premise that stroke may be associated with a history ofH  pylori infection.
Source: Helicobacter - November 15, 2018 Category: Gastroenterology Authors: Tali Shindler ‐Itskovitch, Gabriel Chodick, Varda Shalev, Khitam Muhsen Tags: ORIGINAL ARTICLE Source Type: research

Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications.
Abstract In this editorial we comment on the article by Fukushi K et al published in the recent issue of the World Journal of Gastroenterology 2018; 24(34): 3908-3918. We focus specifically on the mechanisms of the anti-thrombotic action of aspirin, gastric mucosal injury and aging-related increased susceptibility of gastric mucosa to injury. Aspirin is widely used not only for the management of acute and chronic pain and arthritis, but also importantly for the primary and secondary prevention of cardiovascular events such as myocardial infarcts and strokes. Clinical trials have consistently shown that antiplatele...
Source: World Journal of Gastroenterology : WJG - November 14, 2018 Category: Gastroenterology Authors: Tarnawski AS, Ahluwalia A Tags: World J Gastroenterol Source Type: research

Helicobacter pylori infection: old and new.
Authors: Diaconu S, Predescu A, Moldoveanu A, Pop CS, Fierbințeanu-Braticevici C Abstract Helicobacter pylori is a spiral-shaped bacterium that grows in the digestive tract and may be present in more than half of the world's population. The clinical features of Helicobacter pylori range from asymptomatic gastritis to gastrointestinal malignancy. Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B-cell marginal zone lymphoma and Helicobacter pylori has been detected in more than 75% of the patients with MALT lymphoma. Many tests for the detection of Helicobacter pylori are available, including antibo...
Source: Journal of Medicine and Life - June 17, 2017 Category: General Medicine Tags: J Med Life Source Type: research

A potential impact of Helicobacter pylori infection on both obstructive sleep apnea and atrial fibrillation-related stroke
Poli et al [1] concluded that atrial fibrillation (AF) was a major source of stroke in patients with high prevalence of obstructive sleep apnea (OSA).
Source: Sleep Medicine - March 30, 2017 Category: Sleep Medicine Authors: Constantinos Kountouras, Stergios A. Polyzos, Christos Stergiopoulos, Panagiotis Katsinelos, Dimitri Tzivras, Christos Zavos, Elisabeth Vardaka, Emmanuel Gavalas, Efi Vlachogianni, Ioanna Tzivras, Efimia Vlachaki, Georgia Deretzi, Evaggelia Giartza-Taxido Tags: Letter to the Editor Source Type: research

Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management.
Abstract Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effects of bleeding, including gastrointestinal bleeding (GIB). Results from both randomized clinical trials and observations studies suggest that high-dose dabigatran (150 mg b.i.d), rivaroxaban and high-dose edoxaban (6...
Source: World Journal of Gastroenterology : WJG - March 21, 2017 Category: Gastroenterology Authors: Cheung KS, Leung WK Tags: World J Gastroenterol Source Type: research

Population attributable burden of Helicobacter pylori -related gastric cancer, coronary heart disease, and ischemic stroke in China
AbstractHelicobacter pylori, a risk factor of cancer and chronic diseases, remains highly prevalent in China. This review aims to systematically evaluate theH. pylori-attributable burden for gastric cancer (GC), coronary heart disease (CHD), and ischemic stroke (IS) in the Chinese population.Helicobacter pylori prevalence was updated by pooling the results reported in studies across China. The population attributable fraction (PAF) was calculated based on theH. pylori prevalence 10  years ago and relative risks of specific disease by reviewing the prospective studies published from 2000 through 2015. In China, the nationw...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 22, 2017 Category: Microbiology Source Type: research

Carotid intima media thickness and blood biomarkers of atherosclerosis in patients after stroke or myocardial infarction.
CONCLUSIONS: Our study supports linear correlations between CIMT and IC and hs-CRP levels. However, these associations seem to depend on the type of vascular burden. PMID: 28051279 [PubMed - in process]
Source: Croatian Medical Journal - December 31, 2016 Category: Journals (General) Authors: Kurkowska-Jastrzebska I, Karlinski MA, Błazejewska-Hyzorek B, Sarzynska-Dlugosz I, Filipiak KJ, Czlonkowska A Tags: Croat Med J Source Type: research

Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers.
Conclusions. Concomitant use of NSAIDs or anticoagulants, comorbidities (cerebrovascular disease), and male gender are the most important independent risk factors for ulcer on endoscopy in low-dose aspirin consumers, in a population with a high prevalence of H. pylori infection. PMID: 27579036 [PubMed]
Source: Gastroenterology Research and Practice - September 2, 2016 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease.
Abstract Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation. In addition, low dose aspirin is employed as an anti-coagulant for those who have suffered or are at high risk of ischemic stroke and cardiovascular disease. However, NSAIDs and aspirin are injurious to mucosa of stomach and duodenum. NSAID-induced inhibition of mucosal prostaglandin synthesis is thought to be a major mechanism of gastrointestinal mucosal injury. The proportion of elderly has increased rapidl...
Source: Korean J Gastroenter... - June 19, 2016 Category: Gastroenterology Authors: Shim YK, Kim N Tags: Korean J Gastroenterol Source Type: research

Top 20 Research Studies of 2015 for Primary Care Physicians.
This article, the fifth installment in this annual series, summarizes the 20 POEMs based on original research studies judged to have the greatest clinical relevance for family physicians. Key recommendations include questioning the need for backup throat cultures; avoiding early imaging and not adding cyclobenzaprine or oxycodone to naproxen for patients with acute low back pain; and encouraging patients with chronic or recurrent low back pain to walk. Other studies showed that using a nicotine patch for more than eight weeks has little benefit; that exercise can prevent falls that cause injury in at-risk older women; and ...
Source: American Family Physician - May 1, 2016 Category: Primary Care Authors: Ebell MH, Grad R Tags: Am Fam Physician Source Type: research

Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self‐controlled study designs.
ConclusionsThere was some evidence for a short term association for first MI but none for a long term association for any outcome.
Source: British Journal of Clinical Pharmacology - April 19, 2016 Category: Drugs & Pharmacology Authors: Adrian A. Root, Angel Y. S. Wong, Yonas Ghebremichael‐Weldeselassie, Liam Smeeth, Krishnan Bhaskaran, Stephen J. W. Evans, Ruth Brauer, Ian Chi Kei Wong, Vidya Navaratnam, Ian Douglas Tags: Pharmacoepidemiology Source Type: research

Association between infection and carotid atherosclerosis in patients with vascular dementia
This study aimed to investigate the relationship between Hp infection and carotid atherosclerosis in patients with VD.
Source: Journal of the Neurological Sciences - January 16, 2016 Category: Neurology Authors: Yuzhen Xu, Qian Wang, Yunlin Liu, Ruiting Cui, Kaili Lu, Yuwu Zhao Source Type: research

What Your Blood Type Means For Your Health
ImageContent(5627c16ae4b08589ef4a227d,5627c0981400006f003c8c87,Image,HectorAssetUrl(5627c0981400006f003c8c87,Some(crop_29_110_3211_2335),Some(jpeg)),AlexRaths via Getty Images,) EmbedContent(5627c16ae4b08589ef4a227e,SPECIAL FROM ,Embed,html,Some({})) Quick: What’s your blood type? If you’re scratching your head, you may be missing out on an important health clue. A spate of recent research suggests that your blood type—whether A, B, AB, or O—may influence your risk for a variety of health conditions, from cardiac disease to cancer.   The research is still early and scientists aren’t yet s...
Source: Healthy Living - The Huffington Post - October 25, 2015 Category: Consumer Health News Source Type: news

Infectious Burden and Cognitive Decline in the Northern Manhattan Study
ConclusionA quantitative stroke risk‐weighted measure of IB explained variability in baseline executive function performance and associated with decline in memory. Past exposure to common infections may contribute to vascular cognitive impairment and warrants further study.
Source: Journal of the American Geriatrics Society - August 20, 2015 Category: Geriatrics Authors: Clinton B. Wright, Hannah Gardener, Chuanhui Dong, Mitsuhiro Yoshita, Charles DeCarli, Ralph L. Sacco, Yaakov Stern, Mitchell S. V. Elkind Tags: Clinical Investigations Source Type: research

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include citrus and melanoma, a new oral medication for obesity, stroke treatment guidelines, and a vaccine for Helicobacter pylori.
Source: MedPage Today Dermatology - July 5, 2015 Category: Dermatology Source Type: news

Helicobacter Pylori Infection and Risk of Death From Cardiovascular Disease Among the Japanese Population: a Nested Case-Control Study within the JACC Study.
CONCLUSION: The results of this nested case-control study suggest that there is no association between H. pylori infection and CHD and stroke mortality risk in otherwise healthy, elderly Japanese individuals. PMID: 26084791 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 20, 2015 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Predictors of Gastrointestinal Bleeding Among Patients with Atrial Fibrillation After Initiating Dabigatran Therapy
ConclusionThe risk of GI bleeding in patients receiving dabigatran is highly associated with increased age and cardiovascular, renal, and other comorbidities, even after adjusting for other factors. Fewer than 50% of patients restarted an anticoagulant after experiencing a GI bleed. Clinicians should continue to monitor for these risk factors or consider whether alternative therapies may be appropriate.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - May 1, 2015 Category: Drugs & Pharmacology Authors: Julie C. Lauffenburger, Denise H. Rhoney, Joel F. Farley, Anil K. Gehi, Gang Fang Tags: Original Research Article Source Type: research

Anticardiolipin Antibodies in Children with Helicobacter pylori Infection
ConclusionsIn our particular experience, H. pylori can cause aCL antibody positivity in children and eradication of H. pylori provides the disappearance of these antibodies.
Source: Helicobacter - April 1, 2015 Category: Gastroenterology Authors: Serdar Umit Sarıcı, Orhan Gursel, Emin Kurekci, Vural Kesik, Avni Atay, Vedat Okutan, Ali Inal, Aysel Pekel, Mehmet Ali Ozguven, Okan Ozcan Tags: Original Article Source Type: research

Role of Helicobacter pylori infection in pathogenesis of atherosclerosis.
Abstract Though a century old hypothesis, infection as a cause for atherosclerosis is still a debatable issue. Epidemiological and clinical studies had shown a possible association but inhomogeneity in the study population and study methods along with potential confounders have yielded conflicting results. Infection triggers a chronic inflammatory state which along with other mechanisms such as dyslipidemia, hyper-homocysteinemia, hypercoagulability, impaired glucose metabolism and endothelial dysfunction, contribute in pathogenesis of atherosclerosis. Studies have shown a positive relations between Cytotoxic asso...
Source: World Journal of Cardiology - March 26, 2015 Category: Cardiology Authors: Vijayvergiya R, Vadivelu R Tags: World J Cardiol Source Type: research

Estimates of benefits and harms of prophylactic use of aspirin in the general population
Conclusions Prophylactic aspirin use for a minimum of 5 years at doses between 75 and 325 mg/day appears to have favourable benefit–harm profile; longer use is likely to have greater benefits. Further research is needed to determine the optimum dose and duration of use, to identify individuals at increased risk of bleeding, and to test effectiveness of Helicobacter pylori screening–eradication before starting aspirin prophylaxis.
Source: Annals of Oncology - December 17, 2014 Category: Cancer & Oncology Authors: Cuzick, J., Thorat, M. A., Bosetti, C., Brown, P. H., Burn, J., Cook, N. R., Ford, L. G., Jacobs, E. J., Jankowski, J. A., La Vecchia, C., Law, M., Meyskens, F., Rothwell, P. M., Senn, H. J., Umar, A. Tags: reviews Source Type: research

Helicobacter pylori infection increases subsequent ischemic stroke risk: a nationwide population-based retrospective cohort study
Conclusion: Chronic HP-I is significantly associated with an increased risk of IS, particularly nonembolic IS. Anti-HP therapy may be beneficial to IS prevention.
Source: QJM - November 24, 2014 Category: Internal Medicine Authors: Huang, W.- S., Tseng, C.- H., Lin, C.- L., Tsai, C.- H., Kao, C.- H. Tags: Original papers Source Type: research

Association between Infection and Stroke: A Meta-analysis of Prospective Observational Studies
Some studies have suggested an association between Helicobacter pylori infection and the risk of stroke, but the relationship remains controversial. The aim of this study was to obtain a more comprehensive estimate of H. pylori on the risk of stroke by performing a meta-analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2014 Category: Neurology Authors: Min Yu, Yangbo Zhang, Zhen Yang, Jiangwu Ding, Chuan Xie, Nonghua Lu Tags: Original Article Source Type: research

Association between Helicobacter pylori Infection and Stroke: A Meta-analysis of Prospective Observational Studies
Conclusions: In conclusion, our formal meta-analysis indicated no strong association between H. pylori infection and stroke, neither in those with cytotoxin-associated gene-A–positive infection. We believe that future epidemiologic studies of H. pylori and stroke are unlikely to be fruitful.
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2014 Category: Neurology Authors: Min Yu, Yangbo Zhang, Zhen Yang, Jiangwu Ding, Chuan Xie, Nonghua Lu Tags: Original Articles Source Type: research

A study on the association between infectious burden and Alzheimer's disease
ConclusionsIB consisting of CMV, HSV‐1, B. burgdorferi, C. pneumoniae and H. pylori is associated with AD. This study supports the role of infection/inflammation in the etiopathogenesis of AD.
Source: European Journal of Neurology - June 9, 2014 Category: Neurology Authors: X.‐L. Bu, X.‐Q. Yao, S.‐S. Jiao, F. Zeng, Y.‐H. Liu, Y. Xiang, C.‐R. Liang, Q.‐H. Wang, X. Wang, H.‐Y. Cao, X. Yi, B. Deng, C.‐H. Liu, J. Xu, L.‐L. Zhang, C.‐Y. Gao, Z.‐Q. Xu, M. Zhang, L. Wang, X.‐L. Tan, X. Xu, H.‐D. Zhou, Y. Tags: Original Article Source Type: research

Metabolic consequences of Helicobacter pylori infection and eradication.
Abstract Helicobacter pylori (H. pylori) is still the most prevalent infection of the world. Colonization of the stomach by this agent will invariably induce chronic gastritis which is a low-grade inflammatory state leading to local complications (peptic ulcer, gastric cancer, lymphoma) and remote manifestations. While H. pylori does not enter circulation, these extragastric manifestations are probably mediated by the cytokines and acute phase proteins produced by the inflammed mucosa. The epidemiologic link between the H. pylori infection and metabolic changes is inconstant and controversial. Growth delay was des...
Source: World Journal of Gastroenterology : WJG - May 14, 2014 Category: Gastroenterology Authors: Buzás GM Tags: World J Gastroenterol Source Type: research

H. Pylori May Protect Against Stroke
A new study by NYU School of Medicine researchers reveals that an especially virulent strain of the gut bacterium Helicobacter pylori (H. pylori) isn't implicated in the overall death rate of the U.S. population, and may even protect against stroke and some cancers. The findings, based a nationwide health survey of nearly 10,000 individuals over a period of some 12 years, were published online recently in the journal Gut. Those individuals carrying the most virulent strain of H...
Source: Health News from Medical News Today - January 10, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Disappearing bacterium may protect against stroke
(NYU Langone Medical Center / New York University School of Medicine) A new study by NYU School of Medicine researchers reveals that an especially virulent strain of the gut bacterium Helicobacter pylori isn't implicated in the overall death rate of the US population, and may even protect against stroke and some cancers.
Source: EurekAlert! - Medicine and Health - January 9, 2013 Category: Global & Universal Source Type: news

Stroke Drug Kills Bacteria That Cause Ulcers And Tuberculosis
A drug currently being used to treat ischemic strokes may prove to be a significant advance in the treatment of tuberculosis and ulcers. In a new research report appearing online in The FASEB Journal, a compound called ebselen effectively inhibits the thioredoxin reductase system in a wide variety of bacteria, including Helicobacter pylori which causes gastric ulcers and Mycobacterium tuberculosis which causes tuberculosis. Thioredoxin and thioredoxin reductase proteins are essential for bacteria to make new DNA, and protect them against oxidative stress caused by the immune system...
Source: Health News from Medical News Today - January 2, 2013 Category: Consumer Health News Tags: Tuberculosis Source Type: news