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Persisting consequences of ischemic stroke after three months, assessed with the Stroke Impact Scale Version 3.0
CONCLUSION: There is the utmost need to focus on the long-term effects of ischemic stroke, due to the rising number of patients who live with the consequences of stroke. Stroke treatment should not be directed exclusively to acute stroke care or prevention, but also to optimizing the post-stroke functioning and Quality of life.PMID:34991437 | DOI:10.1080/01616412.2021.2024714
Source: Neurological Research - January 7, 2022 Category: Neurology Authors: Mihael Tsalta-Mladenov Silva Andonova Source Type: research

Health-related quality of life after ischemic stroke: impact of sociodemographic and clinical factors
CONCLUSION: Stroke survivors have significantly reduced HR-QoL. Multiple interacting factors are associated with an unfavorable outcome after IS. Early detection of these factors would help to improve the care for IS patients, to reduce disabilities and improve HR-QoL.PMID:33637026 | DOI:10.1080/01616412.2021.1893563
Source: Neurological Research - February 27, 2021 Category: Neurology Authors: M Tsalta-Mladenov S Andonova Source Type: research

A comparison of rt-PA thrombolysis guidelines between China and the USA: are changes needed?
CONCLUSIONS: Onset to IV time is critical for reducing mortality and improving favorable outcomes. We suggest Chinese acute ischemic stroke treatment guidelines be revised to include an increase in the age limit of 80 years, removing contraindications such as a history of previous sever heart, liver, and kidney dysfunction, and placing more emphasis on physician expertise. PMID: 24981554 [PubMed - in process]
Source: Neurological Research - December 2, 2014 Category: Neurology Tags: Neurol Res Source Type: research

The effect of recombinant tissue plasminogen activator on MMP-2 and MMP-9 activities in vitro.
In conclusion, this study showed that rtPA can increase the biological activity of MMP-2 and MMP-9 on posttranslational level. PMID: 24963695 [PubMed - in process]
Source: Neurological Research - December 2, 2014 Category: Neurology Tags: Neurol Res Source Type: research

ASPECT scores of patients with focal intracerebral hemorrhage were correlated with their short- and medium-term functional outcomes
CONCLUSIONS: A low ASPECTS-H was an indicator of poor short-term and long-term functional outcomes of ICH.PMID:34240679 | DOI:10.1080/01616412.2021.1948747
Source: Neurological Research - July 9, 2021 Category: Neurology Authors: Qiuyue Zheng Xiaojie Liu Ke Yan Liang He Yingzhu Chen Source Type: research