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Direct angiographic intervention for acute ischemic stroke with large vessel occlusion
Conclusion:This new approach may provide benefits for appropriately selected patients. Further prospective trials are needed to clarify the risk-versus-benefit of this approach.Abbreviations and Acronyms: AHA: American Heart AssociationAIS: acute ischemic strokeASA: American Stroke AssociationASPECTS: Alberta Stroke Program Early Computed Tomography ScoreCT: computed tomographyCTA: computed tomography angiographyCTP: computed tomography perfusionDMVO: distal, medium vessel occlusionDSA: digital subtraction angiographyED: Emergency DepartmentEVT: endovascular thrombectomyFD: flat detectorIA: intra-arterialIV: intravenousICH...
Source: Neurological Research - June 16, 2021 Category: Neurology Authors: Weizhe Li W Scott Burgin Kanita Beba Abadal Maxim Mokin Zeguang Ren Source Type: research

Matrix metallopeptidase 9 and placental growth factor may correlate with collateral status based on whole-brain perfusion combined with multiphase computed tomography angiography
DISCUSSION: Serum PGF and MMP-9 levels may correlate with collateral status based on MP-CTA in acute ischemic stroke patients with cerebral large artery atherosclerosis. Higher PGF and MMP-9 concentration associated with good collateral status.PMID:34107864 | DOI:10.1080/01616412.2021.1939238
Source: Neurological Research - June 10, 2021 Category: Neurology Authors: Bo Yang Yarong Ding Xin Liu Yuan Cai Xinxuan Yang Qixuan Lu Weibin Gu Liping Liu Yuehua Pu Source Type: research

The relationship between the platelet to leukocyte ratio and mechanical thrombectomy outcomes in acute ischemic stroke patients.
CONCLUSION: Platelet to leukocyte ratio may be use to assess the risk of functional outcome and sICH in patients with acute anterior circulation occlusion stroke undergoing endovascular treatment in real world China. PMID: 32643590 [PubMed - as supplied by publisher]
Source: Neurological Research - July 11, 2020 Category: Neurology Tags: Neurol Res Source Type: research

CT perfusion in predicting the morbidity and prognosis of hypoxic-ischemic encephalopathy after off-pump coronary artery bypass grafting.
CONCLUSION: The difference in occipital lobe rTTP on CTA perfusion may be a potential predictor of HIE. Furthermore, abnormal CT and rTTP may be used for predicting the prognosis in HIE patients. Three principal components (F1 as a reflection of CBF, F2 as reflection of TTP, F3 as a reflection of MTT) can be used to generally describe perfusion parameters. PMID: 28454490 [PubMed - as supplied by publisher]
Source: Neurological Research - May 1, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Frequency and risk factors of spontaneous hemorrhagic transformation following ischemic stroke on the initial brain CT or MRI: data from the China National Stroke Registry (CNSR).
DISCUSSION: Spontaneous HT occurred in 0.92% of the patients with IS in the acute stage. Being female, excess alcohol consumption, atrial fibrillation, and a prolonged period between IS onset and initial imaging were associated with an increased risk of spontaneous HT. PMID: 27320249 [PubMed - in process]
Source: Neurological Research - June 21, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Multi-mode CT in the evaluation of leptomeningeal collateral flow and the related factors: comparing with digital subtraction angiography.
DISCUSSION: Our data showed that multi-mode CT score has a high value in predicting leptomeningeal collateral flow in ischemic stroke. PMID: 27320244 [PubMed - in process]
Source: Neurological Research - June 21, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Internal maxillary artery to intracranial artery bypass: a case series of 31 patients with chronic internal carotid/middle cerebral arterial-sclerotic steno-occlusive disease.
CONCLUSIONS: By supplying an adequate flow to a larger flow territory of chronically stenotic/occlusive major cerebral arteries, IMA bypass surgery is efficient for restoring hemodynamics in selected patients and improving their neurological deficits. PMID: 27122096 [PubMed - as supplied by publisher]
Source: Neurological Research - April 30, 2016 Category: Neurology Tags: Neurol Res Source Type: research

S100β as a biomarker for differential diagnosis of intracerebral hemorrhage and ischemic stroke.
CONCLUSION: S100β could serve as a potential biomarker for differentiating between ICH and IS and predicting short-term functional outcome after ICH. PMID: 27078704 [PubMed - as supplied by publisher]
Source: Neurological Research - April 16, 2016 Category: Neurology Tags: Neurol Res Source Type: research