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Platelet Function Tests Predicting the Efficacy and Safety of Aspirin Secondary Prevention
CONCLUSIONS: Of the three tests assessed, the predictive accuracies of PFA and LTA were satisfying for aspirin secondary prevention, while TEG's performance was poor. Only PFA could provide accurate prognostic information for bleeding.PMID:34581662 | DOI:10.1080/01616412.2021.1981103
Source: Neurological Research - September 28, 2021 Category: Neurology Authors: Yue Cheng Tengfei Shao Lili Huang Hengheng Xu Pengfei Shao Dan Yang Weihong Ge Yun Xu Meijuan Zhang Source Type: research

Risk factors for in-hospital mortality among acute ischemic stroke patients in China: a nationwide prospective study.
Conclusions: The findings from this study may help clinicians control the risk of IHM better for patients with AIS. PMID: 33357098 [PubMed - as supplied by publisher]
Source: Neurological Research - December 29, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The relationship between the platelet to leukocyte ratio and mechanical thrombectomy outcomes in acute ischemic stroke patients.
CONCLUSION: Platelet to leukocyte ratio may be use to assess the risk of functional outcome and sICH in patients with acute anterior circulation occlusion stroke undergoing endovascular treatment in real world China. PMID: 32643590 [PubMed - as supplied by publisher]
Source: Neurological Research - July 11, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The relationship between brain microbleeds and homeostatic markers in the treatment of ischemic stroke.
CONCLUSION: Pathogenesis of AF is involved abnormal changes of hemostasis, endothelial dysfunction, antithrombotic state and inflammation. The homeostatic markers, which play role in these pathways, and the presence of BMBs could use to form a prognostic clinic assessment tool to predict bleeding risk. PMID: 30207930 [PubMed - as supplied by publisher]
Source: Neurological Research - September 14, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Clinical features and outcomes in 154 patients with haemorrhagic moyamoya disease: comparison of conservative treatment and surgical revascularization.
CONCLUSIONS: Age at the initial bleeding is a risk factor for rebleeding in haemorrhagic MMD. Although surgical revascularization showed the tendency to decrease the rebleeding rate, there was no statistical difference between direct revascularization, indirect revascularization, combined revascularization and conservative treatment in preventing rebleeding. Further study is needed to determine whether surgical revascularization is effective in select population or with certain techniques. PMID: 26159234 [PubMed - as supplied by publisher]
Source: Neurological Research - July 12, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Quantitative assessment and correlation analysis of cerebral microbleed distribution and leukoaraiosis in stroke outpatients.
DISCUSSION: Cerebral microbleed incidence increased with age. Mixed CMB type displayed the highest incidence. The severity and number of CMBs at any location correlated with LA severity. These results suggested interactions between hypertension and CAA during LA progression. PMID: 25875577 [PubMed - as supplied by publisher]
Source: Neurological Research - April 17, 2015 Category: Neurology Tags: Neurol Res Source Type: research

The effect of recombinant tissue plasminogen activator on MMP-2 and MMP-9 activities in vitro.
In conclusion, this study showed that rtPA can increase the biological activity of MMP-2 and MMP-9 on posttranslational level. PMID: 24963695 [PubMed - in process]
Source: Neurological Research - December 2, 2014 Category: Neurology Tags: Neurol Res Source Type: research