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Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy
This post hoc analysis of a randomized clinical trial investigates whether the association of clopidogrel-aspirin treatment with stroke recurrence in patients with minor stroke or high-risk transient ischemic attack is modified by the presence of infarct on imaging attributed to the index event.
Source: JAMA Neurology - January 18, 2022 Category: Neurology Source Type: research

Comparison of Ticagrelor vs Clopidogrel With Aspirin in Minor Ischemic Stroke and Transient Ischemic Attack
This network meta-analysis compares ticagrelor and aspirin with clopidogrel and aspirin in patients with acute minor ischemic stroke or transient ischemic attack in the prevention of recurrent strokes or death.
Source: JAMA Neurology - December 6, 2021 Category: Neurology Source Type: research

LV Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs Aspirin
This post hoc analysis evaluates whether anticoagulation is superior to aspirin in reducing recurrent stroke in patients with embolic stroke of undetermined source and left ventricular dysfunction.
Source: JAMA Neurology - October 25, 2021 Category: Neurology Source Type: research

Errors in Results and Table 1
This article was corrected online.
Source: JAMA Neurology - August 16, 2021 Category: Neurology Source Type: research

Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke
This exploratory analysis of the THALES trial evaluates the efficacy and safety of ticagrelor plus aspirin in patients with moderate ischemic stroke (National Institutes of Health Stroke Scale score of 4 to 5).
Source: JAMA Neurology - July 9, 2021 Category: Neurology Source Type: research

Error in Figure
This article has been corrected online.
Source: JAMA Neurology - December 21, 2020 Category: Neurology Source Type: research

Ticagrelor Plus Aspirin in Preventing Disabling Stroke
This randomized clinical trial evaluates the superiority of ticagrelor added to aspirin in preventing disabling stroke and identifies factors associated with recurrent disabling stroke.
Source: JAMA Neurology - November 7, 2020 Category: Neurology Source Type: research

Microbleeds and the Effect of Anticoagulation in Patients With Embolic Stroke of Undetermined Source
This prespecified analysis of a randomized clinical trial investigates the effect of cerebral microbleeds on patients with embolic stroke of undetermined source taking either daily rivaroxaban or aspirin.
Source: JAMA Neurology - October 19, 2020 Category: Neurology Source Type: research

Error in Figure
This article was corrected online.
Source: JAMA Neurology - September 30, 2019 Category: Neurology Source Type: research

Association Between Low-Dose Rivaroxaban With or Without Aspirin and Ischemic Stroke Subtypes
This secondary analysis of a multinational randomized clinical trial of 27  395 participants with systemic atherosclerotic disease examines the association low-dose rivaroxaban plus aspirin, rivaroxaban alone, or aspirin alone and the risk of different ischemic stroke subtypes.
Source: JAMA Neurology - September 16, 2019 Category: Neurology Source Type: research

Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack
This pooled analysis combines data from 2 randomized clinical trials to estimate the efficacy and risk of dual antiplatelet therapy after minor ischemic stroke or transient ischemic attack.
Source: JAMA Neurology - August 19, 2019 Category: Neurology Source Type: research

Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone
This secondary analysis of a randomized clinical trial examines the short-term risk of hemorrhage in treating patients in North America, Europe, and Australasia with acute transient ischemic attack or minor acute ischemic stroke with clopidogrel plus aspirin or aspirin alone.
Source: JAMA Neurology - April 29, 2019 Category: Neurology Source Type: research

Recurrent Stroke With Rivaroxaban Compared With Aspirin
This secondary analysis of a randomized clinical trial investigates whether rivaroxaban is associated with a reduction in recurrent stroke among patients with embolic stroke of undetermined source who have an increased risk of atrial fibrillation.
Source: JAMA Neurology - April 8, 2019 Category: Neurology Source Type: research

ABCB1 Polymorphisms and Outcomes of Clopidogrel Treatment for Minor Stroke or Transient Ischemic Attack
This secondary analysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events (CHANCE) randomized clinical trial investigates the association ofABCB1 polymorphisms with efficacy of clopidogrel plus aspirin vs aspirin alone in patients with minor stroke or transient ischemic attack.
Source: JAMA Neurology - February 11, 2019 Category: Neurology Source Type: research

Enoxaparin vs Aspirin in Patients With Cancer and Ischemic Stroke
This randomized clinical trial compares anticoagulation vs antiplatelet therapy in patients with cancer and acute ischemic stroke.
Source: JAMA Neurology - January 8, 2018 Category: Neurology Source Type: research