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Source: JAHA:Journal of the American Heart Association
Condition: Mitochondrial Disease
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Total 1 results found since Jan 2013.
Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease Stroke
Conclusions
A significant reduction of Ndufc2 expression causes complex I dysfunction and contributes to stroke susceptibility in SHRSP. Moreover, our current evidence may suggest that Ndufc2 can contribute to an increased occurrence of early-onset ischemic stroke in humans.
Source: JAHA:Journal of the American Heart Association - February 17, 2016 Category: Cardiology Authors: Rubattu, S., Di Castro, S., Schulz, H., Geurts, A. M., Cotugno, M., Bianchi, F., Maatz, H., Hummel, O., Falak, S., Stanzione, R., Marchitti, S., Scarpino, S., Giusti, B., Kura, A., Gensini, G. F., Peyvandi, F., Mannucci, P. M., Rasura, M., Sciarretta, S., Tags: Basic Science Research, Gene Expression & Regulation, Cerebrovascular Disease/Stroke Source Type: research
