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Source: Clinical Neurophysiology
Therapy: Stem Cell Therapy
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Total 1 results found since Jan 2013.
P 4 Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblasts migration in the mouse brain after stroke
The phosphoglycoprotein osteopontin (OPN) is upregulated in the brain following cerebral ischemia, where is exerts neuroprotective properties. We previously demonstrated OPN to increase survival and proliferation of neural stem cells (NSC) in vitro and in vivo. In culture, OPN additionally promotes NSC migration as well as a neuronal differentiation fate. Based on these data, we hypothesized OPN to induce NSC migration as well as neurogenesis in vivo as well. We here aimed to establish and visualize these effects using non-invasive in vivo imaging.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: R. Rogall, A. Pikhovych, A. Bach, M. Hoehn, S. Couillard-Despres, G.R. Fink, M. Schroeter, M.A. Rueger Tags: Poster Source Type: research
