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B-11. Application of EEG-based brain computer interface to movement and sensory disorders
To examine the effect of the EEG-based brain computer interface (BCI) training for patients with stroke, writer ’s cramp and neuropathic pain. Method: Using the EEG recorded with Ag/AgCl electrodes placed at C3 and C4, as designated according to the International 10/20 system, we gave real time visual feedback to the patients with PC monitor which is placed in front of them. Participants were required to im agine the affected wrist extending in stroke and neuropathic pain patients. Patients with writer’s cramp were requested to relax their wrist flexor while extending their wrist.
Source: Clinical Neurophysiology - April 26, 2018 Category: Neuroscience Authors: Tetsuo Ota Source Type: research

The Japanese rTMS experience – Present and future
Fig. 8 coil, which is popular now, was invented by Prof. Ueno in 1988 and spread globally. The rTMS machines were developed in Europe and imported to Japan from 2001 and spread over Japan. The clinical treatments with rTMS have been mainly used for Parkinson’s syndrome, neuropathic pain, depression and rehabilitation after stroke. rTMS of left dorsolateral prefrontal cortex (Neuronetics Inc) for depression is already used in Japanese private clinic, and will be approved by Japanese government in the near future.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: Y. Saitoh, K. Hosomi, H. Nakamura, T. Shimizu Source Type: research

ID 99 – Functional connectivity study on repetitive transcranial magnetic stimulation for central post-stroke pain
This study aimed to investigate functional connectivity specific to CPSP and functional connectivity alteration associated with pain relief by rTMS.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: K. Hosomi, T. Shimizu, T. Maruo, Y. Watanabe, H.M. Khoo, N. Tani, Y. Goto, H. Kishima, T. Yoshimine, Y. Saitoh Source Type: research

ID 100 – Chronic post stroke central pain: Increased success rate of chronic epidural motor cortex stimulation using somatotopic, navigated repetitive TMS for patient selection and implant placement
The outcome at group level of neuromodulation for central pain using stimulation of motor cortices is limited, though for some, there are large effects. Thus, there is a need for selection of patients.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: M. Thordstein, G. Pegenius, K. Gatzinsky Source Type: research

27. Botulotoxin in the treatment of spasticity – Our experience
Conclusion: Btx is an effective and safe treatment. An integral part of the treatment program for patients with spasticity must be rehabilitation, stretching, splinting, physical processes. The prerequisite is the motivation and cooperation of patients.
Source: Clinical Neurophysiology - April 7, 2014 Category: Neuroscience Authors: J. Kubik, P. Bodnárová, R. Michánková, P. Klepiš, J. Neumann Tags: Society Proceedings Source Type: research

P 219. Navigated repeated transcranial magnetic stimulation in stroke rehabilitation (randomized blind sham-controlled study), Preliminary results: safety and tolerability
Conclusion: Repeated nTMS is safe and effective add-method in motor post-stroke rehabilitation, but continuous study and forming protocols are necessary to validate this method.ClinicalTrials.gov Identifier: NCT01652677.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: M. Piradov, L. Chernikova, M. Tanashyan, A. Kadykov, A. Chervyakov, M. Nazarova, V. Gnezditsky, R. Konovalov, N. Savitskaya, P. Fedin, A. Suslin, M. Glebov, L. Dobrynina Tags: Society Proceedings Source Type: research

P 168. TMS neurophysiology and interventional rTMS in children with perinatal stroke: Safety and tolerability in the PLASTIC CHAMPS trial
Introduction/Question: Perinatal stroke causes hemiplegic cerebral palsy and lifelong disability. TMS can define neurophysiology and central therapeutic targets while rTMS carries therapeutic potential in adult stroke but have not been applied to the more plastic developing brain. Ipsilateral projections from the unlesioned hemisphere to the affected hand are prominent in this population and the effects of non-lesioned inhibitory rTMS are unknown.Methods: PLASTIC CHAMPS is a randomized, blinded, factorial clinical trial of rTMS and constraint therapy (CIMT) to enhance upper extremity function in children (6–18years) with...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: T. Rajapakse, O. Kirton, J. Roe, A. Kirton Tags: Society Proceedings Source Type: research

P 174. Effects of paired associative stimulation on developmental motor plasticity in children
Introduction: Transcranial magnetic stimulation (TMS) offers increasingly sophisticated means of assessing neurophysiology and neuroplasticity mechanisms but applications in children have been limited. Paired associative stimulation (PAS) is an advanced TMS method that pairs peripheral sensory stimulation with TMS primary motor cortex (M1) stimulation. PAS induces rapid, reversible and topographically specific increases in adult motor cortex excitability consistent with NMDAR-dependent long-term potentiation. PAS has not been studied in the more plastic brains of children.Objectives: Our aim wasto define the developmental ...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: O. Damji, J. Roe, S. Shinde, O. Kotsovsky, A. Kirton Tags: Society Proceedings Source Type: research

P 219. Navigated repeated transcranial magnetic stimulation in stroke rehabilitation (randomized blind sham-controlled study), Preliminary results: safety and tolerability
Conclusion: Repeated nTMS is safe and effective add-method in motor post-stroke rehabilitation, but continuous study and forming protocols are necessary to validate this method.ClinicalTrials.gov Identifier: NCT01652677.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: M. Piradov, L. Chernikova, M. Tanashyan, A. Kadykov, A. Chervyakov, M. Nazarova, V. Gnezditsky, R. Konovalov, N. Savitskaya, P. Fedin, A. Suslin, M. Glebov, L. Dobrynina Tags: Society Proceedings Source Type: research

P 168. TMS neurophysiology and interventional rTMS in children with perinatal stroke: Safety and tolerability in the PLASTIC CHAMPS trial
Introduction/Question: Perinatal stroke causes hemiplegic cerebral palsy and lifelong disability. TMS can define neurophysiology and central therapeutic targets while rTMS carries therapeutic potential in adult stroke but have not been applied to the more plastic developing brain. Ipsilateral projections from the unlesioned hemisphere to the affected hand are prominent in this population and the effects of non-lesioned inhibitory rTMS are unknown.Methods: PLASTIC CHAMPS is a randomized, blinded, factorial clinical trial of rTMS and constraint therapy (CIMT) to enhance upper extremity function in children (6–18years) with...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: T. Rajapakse, O. Kirton, J. Roe, A. Kirton Tags: Society Proceedings Source Type: research

P 174. Effects of paired associative stimulation on developmental motor plasticity in children
Introduction: Transcranial magnetic stimulation (TMS) offers increasingly sophisticated means of assessing neurophysiology and neuroplasticity mechanisms but applications in children have been limited. Paired associative stimulation (PAS) is an advanced TMS method that pairs peripheral sensory stimulation with TMS primary motor cortex (M1) stimulation. PAS induces rapid, reversible and topographically specific increases in adult motor cortex excitability consistent with NMDAR-dependent long-term potentiation. PAS has not been studied in the more plastic brains of children.Objectives: Our aim wasto define the developmental ...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: O. Damji, J. Roe, S. Shinde, O. Kotsovsky, A. Kirton Tags: Society Proceedings Source Type: research

S1-1. Spinal cord stimulation for post-stroke pain
Spinal cord stimulation (SCS) is used to treat for several types of intractable pain syndromes, but it is not commonly used for treating post-stroke pain. Therefore, in this study, we analyzed the effects of SCS in patients with post-stroke pain. Neurological imaging and pharmacological analysis using thiopental, ketamine and morphine tests were conducted for 30 patients with post-stroke pain. For all patients, percutaneous electrodes were inserted under local anesthesia, and trial stimulation was performed for 5–7days. If the patient experienced pain relief during the trial stimulation, a pulse generator was implanted. ...
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Toshiki Obuchi, Mitsuru Watanabe, Koichiro Sumi, Toshikazu Kano, Kazutaka Kobayashi, Hideki Oshima, Chikashi Fukaya, Atsuo Yoshino, Takamitsu Yamamoto, Yoichi Katayama Tags: Society Proceedings Source Type: research

S1-4. The effect of repetitive Transcranial Magnetic Stimulation (rTMS) in patients with intractable cervical dystonia and/or post-stroke central pain
In conclusion, rTMS is useful as one of the option in the treatment of intractable CD and CPSP.
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Norihiro Muraoka, Minoru Shigemori, Fumihiko Koike, Masao Hiromatu, Keiko Suematu, Motohiro Morioka Tags: Society Proceedings Source Type: research

The three dimensional assessment of peripheral nerve injury: An integrated clinical, neurophysiologic and sonographic approach
“Time is brain,” a phrase common to neurologists, emphasizes the importance of immediate evaluation for acute stroke (). In the realm of peripheral nerve injury (PNI), the opportunity for acute diagnosis is often dictated by the temporal evolution of neurophysiologic findings, limiting the value of acute assessment. The findings of Padua et al. in this issue of Clinical Neurophysiology may increase the urgency to assess PNI (). PNI owing to traumatic and iatrogenic injury is quite common, with an incidence as high as 34% in traumatic brain injury patients () and is found in up to 5% of all patients admitted to trauma c...
Source: Clinical Neurophysiology - February 4, 2013 Category: Neuroscience Authors: Lisa D. Hobson-Webb, Vern C. Juel Tags: Editorials Source Type: research