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Risk of Major Cardiovascular and Neurologic Events with Obstructive Sleep Apnea among Patients with Atrial Fibrillation
ConclusionAmong patients with AF, OSA is an independent risk factor for MACNE and, more specifically, stroke/SE.Graphical Abstract
Source: American Heart Journal - January 7, 2020 Category: Cardiology Source Type: research

Guideline-directed therapies for comorbidities and clinical outcomes among individuals with atrial fibrillation
ConclusionsIn AF patients, there is underuse of GDT for non-AF comorbidities. The association between GDT use and outcomes was strongest in heart failure and obstructive sleep apnea patients where use of GDT was associated with lower mortality and less AF progression.
Source: American Heart Journal - November 9, 2019 Category: Cardiology Source Type: research

Reducing cardiovascular risk through treatment of obstructive sleep apnea: 2 methodological approaches
This article describes 2 independent studies that worked collaboratively to fill these gaps. The populations, design features, and relative benefits/challenges of the 2 studies (SleepTight and BestAIR) are described. Both studies were encouraged to have multidisciplinary teams with expertise in behavioral interventions to improve PAP compliance. Both studies provide key information that will be useful to the research community in future large-scale, event-driven, randomized trials to evaluate the efficacy and/or effectiveness of strategies to identify and treat significant OSA for decreasing risk of major adverse cardiovas...
Source: American Heart Journal - December 22, 2015 Category: Cardiology Source Type: research

Reducing Cardiovascular Risk through Treatment of Obstructive Sleep Apnea: Two Methodological Approaches
Publication date: Available online 11 September 2015 Source:American Heart Journal Author(s): Klar Yaggi, Murray A. Mittleman, Dawn M. Bravata, John Concato, James Ware, Catherine M. Stoney, Susan Redline Obstructive sleep apnea (OSA) significantly impacts cardiovascular health, demonstrated by observational investigations showing an independently increased risk of ischemic heart disease, diabetes, hypertension, congestive heart failure, acute coronary syndrome, stroke, cardiovascular mortality, and all-cause mortality. Positive airway pressure (PAP), a medical therapy for sleep apnea, reverses airway obstruction ...
Source: American Heart Journal - September 11, 2015 Category: Cardiology Source Type: research

Impact of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Outcomes in Patients with Atrial Fibrillation – Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)
Conclusion Compared with those without, AF patients with obstructive sleep apnea have worse symptoms and higher risks of hospitalization, but similar mortality, major adverse cardiovascular outcome and AF progression rates. Clinical Trial Registration: NCT01165710 (http://www.clinicaltrials.gov)
Source: American Heart Journal - February 7, 2015 Category: Cardiology Source Type: research