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Source: Thrombosis and Haemostasis
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Total 528 results found since Jan 2013.
Reticulated Platelets Predict Cardiovascular Death and Adverse Events in Coronary Artery Disease: A Systematic Review and Meta-analysis
CONCLUSION: Elevated RPs are significantly associated with increased risk of cardiovascular events and cardiovascular death.PMID:37696301 | DOI:10.1055/s-0043-1773763
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Dario Bongiovanni Laura Novelli Francesco Condello Kilian Kirmes Jiaying Han Bastian Wein S ébastien Elvinger Giacomo Viggiani Moritz von Scheidt Karl-Ludwig Laugwitz Philip W J Raake Adnan Kastrati Mauro Chiarito Isabell Bernlochner Source Type: research
Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach
CONCLUSION: Long-term TXA treatment does not alter brain Aβ levels or impact neurologic behavior in mice predisposed to amyloid deposition and had minor effects on the levels of inflammatory mediators. This finding supports the safety of TXA and lays the foundation for TXA as a novel treatment to reduce sICH in patients with CAA.PMID:37694270 | PMC:PMC10483050 | DOI:10.1016/j.rpth.2023.102166
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Zikou Liu Fiona M McCutcheon Heidi Ho Joanne Chia Yunxin Xiao Isabel Tippett Charithani B Keragala Geoffrey C Cloud Robert L Medcalf Source Type: research
Lipoprotein(a) and risk of cognitive impairment in Black and White Americans: the Reasons for Geographic and Racial Differences in Stroke cohort
CONCLUSION: Higher Lp(a) was associated with increased risk of cognitive impairment in Black but not White individuals. Future studies should evaluate the biological and social mechanisms through which race and Lp(a) interact to increase risk of cognitive impairment.PMID:37694266 | PMC:PMC10491800 | DOI:10.1016/j.rpth.2023.102170
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Miguel Arce Renter ía Leslie A McClure Peter W Callas Vanessa M LaBode-Richman Danielle S Kroll Jennifer J Manly Neil A Zakai Frederick Unverzagt Mary Cushman Source Type: research
Tranexamic acid in a mouse model of cerebral amyloid angiopathy: setting the stage for a novel stroke treatment approach
CONCLUSION: Long-term TXA treatment does not alter brain Aβ levels or impact neurologic behavior in mice predisposed to amyloid deposition and had minor effects on the levels of inflammatory mediators. This finding supports the safety of TXA and lays the foundation for TXA as a novel treatment to reduce sICH in patients with CAA.PMID:37694270 | PMC:PMC10483050 | DOI:10.1016/j.rpth.2023.102166
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Zikou Liu Fiona M McCutcheon Heidi Ho Joanne Chia Yunxin Xiao Isabel Tippett Charithani B Keragala Geoffrey C Cloud Robert L Medcalf Source Type: research
Lipoprotein(a) and risk of cognitive impairment in Black and White Americans: the Reasons for Geographic and Racial Differences in Stroke cohort
CONCLUSION: Higher Lp(a) was associated with increased risk of cognitive impairment in Black but not White individuals. Future studies should evaluate the biological and social mechanisms through which race and Lp(a) interact to increase risk of cognitive impairment.PMID:37694266 | PMC:PMC10491800 | DOI:10.1016/j.rpth.2023.102170
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Miguel Arce Renter ía Leslie A McClure Peter W Callas Vanessa M LaBode-Richman Danielle S Kroll Jennifer J Manly Neil A Zakai Frederick Unverzagt Mary Cushman Source Type: research
Non-vitamin K Antagonist Oral Anticoagulant, Warfarin, and ABC Pathway Adherence on Hierarchical Outcomes: Win Ratio Analysis of the COOL-AF Registry
CONCLUSION: This Win Ratio analysis demonstrates the significant benefits of NOACs over warfarin and ABC pathway adherence over nonadherence in reducing the composite outcome in patients with AF.PMID:37625457 | DOI:10.1055/s-0043-1772773
Source: Thrombosis and Haemostasis - August 25, 2023 Category: Hematology Authors: Sukrit Treewaree Gregory Y H Lip Rungroj Krittayaphong Source Type: research
What is the diameter of a fibrin fiber?
CONCLUSION: We performed a systematic, multitechnique survey assessing fibrin fiber diameters under a range of biochemical conditions. The similarity in the diameter values obtained using SEM and superresolution imaging suggests that drying and fixation during SEM sample preparation do not dramatically alter fiber cross-sections. Congruence, under certain conditions, between diameter values obtained using SEM, superresolution fluorescence imaging, and turbidimetry demonstrates the feasibility of a fibrin diameter standardization project.PMID:37601015 | PMC:PMC10439396 | DOI:10.1016/j.rpth.2023.100285
Source: Thrombosis and Haemostasis - August 21, 2023 Category: Hematology Authors: Heather A Belcher Martin Guthold Nathan E Hudson Source Type: research
Outcomes in infants with unprovoked venous thromboembolism: A retrospective cohort study
CONCLUSION: There is a low rate of recurrent VTE but significant end-organ morbidity in infants with unprovoked VTE.PMID:37538506 | PMC:PMC10394551 | DOI:10.1016/j.rpth.2023.100174
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Hilary Whitworth Lauren A Beslow Rebecca A Hubbard Charles E Leonard Rebecca Scobell Char Witmer Leslie Raffini Source Type: research
Thrombus composition and thrombolysis resistance in stroke
Res Pract Thromb Haemost. 2023 May 16;7(4):100178. doi: 10.1016/j.rpth.2023.100178. eCollection 2023 May.ABSTRACTA State of the Art lecture titled "Thrombus Composition and Thrombolysis Resistance in Stroke" was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) remains the only pharmacologic option to re-establish cerebral perfusion at the acute phase of ischemic stroke. IVT is based on the administration of recombinant tissue plasminogen activator with the objective of dissolving fibrin, the major fibrillar protein component of thrombi. Almost 30 years on from its introduction, although the clinical b...
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Benoit Ho-Tin-No é Jean-Philippe Desilles Mikael Mazighi Source Type: research
Outcomes in infants with unprovoked venous thromboembolism: A retrospective cohort study
CONCLUSION: There is a low rate of recurrent VTE but significant end-organ morbidity in infants with unprovoked VTE.PMID:37538506 | PMC:PMC10394551 | DOI:10.1016/j.rpth.2023.100174
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Hilary Whitworth Lauren A Beslow Rebecca A Hubbard Charles E Leonard Rebecca Scobell Char Witmer Leslie Raffini Source Type: research
Thrombus composition and thrombolysis resistance in stroke
Res Pract Thromb Haemost. 2023 May 16;7(4):100178. doi: 10.1016/j.rpth.2023.100178. eCollection 2023 May.ABSTRACTA State of the Art lecture titled "Thrombus Composition and Thrombolysis Resistance in Stroke" was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) remains the only pharmacologic option to re-establish cerebral perfusion at the acute phase of ischemic stroke. IVT is based on the administration of recombinant tissue plasminogen activator with the objective of dissolving fibrin, the major fibrillar protein component of thrombi. Almost 30 years on from its introduction, although the clinical b...
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Benoit Ho-Tin-No é Jean-Philippe Desilles Mikael Mazighi Source Type: research
