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Maternal and neonatal complications in women with congenital heart disease: a nationwide analysis
ConclusionsThis population-based study illustrates a reassuringly low maternal mortality rate in a highly developed healthcare system. Nevertheless, maternal morbidity and neonatal morbidity/mortality were significantly increased in women with ACHD and their offspring compared to non-ACHD controls highlighting the need of specialized care and pre-pregnancy counselling.
Source: European Heart Journal - October 12, 2021 Category: Cardiology Source Type: research

Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy
ConclusionPatients with childhood-onset HCM are more likely to have sarcomeric disease, carry a higher risk of life-threatening ventricular arrythmias, and have greater need for advanced HF therapies. These findings provide insight into the natural history of disease and can help inform clinical risk stratification.
Source: European Heart Journal - March 26, 2021 Category: Cardiology Source Type: research

Arrhythmia-associated risk: from cardiac arrest to stroke and dementia
Source: European Heart Journal - December 26, 2020 Category: Cardiology Source Type: research

Long working hours as a risk factor for atrial fibrillation: a multi-cohort study
ConclusionIndividuals who worked long hours were more likely to develop atrial fibrillation than those working standard hours.
Source: European Heart Journal - July 13, 2017 Category: Cardiology Source Type: research

Long-term symptom improvement and patient satisfaction following catheter ablation of supraventricular tachycardia: insights from the German ablation registry
Conclusion</div>Ablation therapy for SVT is a safe procedure bringing symptomatic improvement and satisfaction to three quarters of patients after 1 year. Even in patients with arrhythmia recurrence, a high satisfaction level and adherence to the ablating institution could be documented. Strikingly high mortality and stroke rates in follow-up were observed in AFL patients, who apparently need consistent long-term anticoagulation and more medical attention.</span>
Source: European Heart Journal - March 17, 2017 Category: Cardiology Source Type: research

Frontiers in heart failure: sodium, longitudinal strain, contractility sensor, fatal arrhythmias, and stroke
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Source: European Heart Journal - March 9, 2017 Category: Cardiology Source Type: research

A frameshift deletion in the sarcomere gene MYL4 causes early-onset familial atrial fibrillation
Conclusions</div>Through a population approach we found a loss of function mutation in the myosin gene <span style="font-style:italic;">MYL4</span> that, in the homozygous state, is completely penetrant for early-onset AF. The finding may provide novel mechanistic insight into the pathophysiology of this complex arrhythmia.</span>
Source: European Heart Journal - October 13, 2016 Category: Cardiology Source Type: research

Catheter ablation for atrial fibrillation is associated with lower incidence of stroke and death: data from Swedish health registries
Conclusion Ablation may be associated with lower incidence of ischaemic stroke and death in patients with AF. This beneficial finding appears more pronounced in patients with higher thromboembolic risk.
Source: European Heart Journal - August 23, 2016 Category: Cardiology Authors: Friberg, L., Tabrizi, F., Englund, A. Tags: Arrhythmia/electrophysiology Source Type: research

Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices
Conclusion In patients with implanted defibrillators, the strategy of early initiation and interruption of anticoagulation based on remotely detected AT did not prevent thromboembolism and bleeding. Clinical trial registration IMPACT ClinicalTrials.gov identifier: NCT00559988 http://clinicaltrials.gov/ct2/show/NCT00559988?term=NCT00559988&rank=1.
Source: European Heart Journal - July 7, 2015 Category: Cardiology Authors: Martin, D. T., Bersohn, M. M., Waldo, A. L., Wathen, M. S., Choucair, W. K., Lip, G. Y. H., Ip, J., Holcomb, R., Akar, J. G., Halperin, J. L., on behalf of the IMPACT Investigators Tags: Atrial fibrillation Source Type: research

Prognostic impact of supraventricular premature complexes in community-based health checkups: The Ibaraki Prefectural Health Study
Conclusion The presence of SVPCs in 12-lead electrocardiograms was a strong predictor of AF development, and associated with increased risk of CVD in general population.
Source: European Heart Journal - January 17, 2015 Category: Cardiology Authors: Murakoshi, N., Xu, D., Sairenchi, T., Igarashi, M., Irie, F., Tomizawa, T., Tada, H., Sekiguchi, Y., Yamagishi, K., Iso, H., Yamaguchi, I., Ota, H., Aonuma, K. Tags: Arrhythmia/electrophysiology Source Type: research

The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association
Conclusion The AFib Ablation Pilot Study provided crucial information on the epidemiology, management, and outcomes of catheter ablation of AFib in a real-world setting. The methods used to assess the success of the procedure appeared at least suboptimal. Even in this context, the 12-month success rate appears to be somewhat lower to the one reported clinical trials.
Source: European Heart Journal - June 7, 2014 Category: Cardiology Authors: Arbelo, E., Brugada, J., Hindricks, G., Maggioni, A. P., Tavazzi, L., Vardas, P., Laroche, C., Anselme, F., Inama, G., Jais, P., Kalarus, Z., Kautzner, J., Lewalter, T., Mairesse, G. H., Perez-Villacastin, J., Riahi, S., Taborsky, M., Theodorakis, G., Tri Tags: Arrhythmia/electrophysiology Source Type: research

Outbursts of anger as a trigger of acute cardiovascular events: a systematic review and meta-analysis
Conclusion There is a higher risk of cardiovascular events shortly after outbursts of anger.
Source: European Heart Journal - June 3, 2014 Category: Cardiology Authors: Mostofsky, E., Penner, E. A., Mittleman, M. A. Tags: Prevention and epidemiology Source Type: research

Does remote ischaemic preconditioning with postconditioning improve clinical outcomes of patients undergoing cardiac surgery? Remote Ischaemic Preconditioning with Postconditioning Outcome Trial
Conclusion Remote ischaemic preconditioning with RIPostC by transient upper limb ischaemia did not improve clinical outcome in patients who underwent cardiac surgery. Clinical Trial Registration clinicaltrials.gov, NCT00997217.
Source: European Heart Journal - January 14, 2014 Category: Cardiology Authors: Hong, D. M., Lee, E.-H., Kim, H. J., Min, J. J., Chin, J.-H., Choi, D.-K., Bahk, J.-H., Sim, J.-Y., Choi, I.-C., Jeon, Y. Tags: Acute coronary syndromes Source Type: research

Prognostic significance of prolonged PR interval in the general population
Conclusion In the middle-aged general population, prolonged PR interval normalizes in a substantial proportion of subjects during the time course, and it is not associated with an increased risk of all-cause or cardiovascular mortality.
Source: European Heart Journal - January 7, 2014 Category: Cardiology Authors: Aro, A. L., Anttonen, O., Kerola, T., Junttila, M. J., Tikkanen, J. T., Rissanen, H. A., Reunanen, A., Huikuri, H. V. Tags: Arrhythmia/electrophysiology Source Type: research

A new look at atrial fibrillation: lessons learned from drugs, pacing, and ablation therapies
Atrial fibrillation (AF) is the most common arrhythmia and among the leading causes of stroke and heart failure in Western populations. Despite the increasing size of clinical trials assessing the efficacy and safety of AF therapies, achieved outcomes have not always matched expectations. Considering that AF is a symptom of many possible underlying diseases, clinical research for this arrhythmia should take into account their respective pathophysiology. Accordingly, the definition of the study populations to be included should rely on the established as well as on the new classifications of AF and take advantage from a dif...
Source: European Heart Journal - September 14, 2013 Category: Cardiology Authors: Kappenberger, L. Tags: REVIEWS Source Type: research

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