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Specialty: Cardiology
Source: JAHA:Journal of the American Heart Association

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Total 381 results found since Jan 2013.

Nonsustained Atrial Fibrillation in Ischemic Stroke Patients and Stroke-Free Controls From the Perspective of Stroke Pathophysiology Stroke
BackgroundShort‐lasting (
Source: JAHA:Journal of the American Heart Association - September 29, 2016 Category: Cardiology Authors: Yetim, E., Topcuoglu, M. A., Canpolat, U., Gocmen, R., Oguz, K. K., Ozer, N., Aytemir, K., Arsava, E. M. Tags: Atrial Fibrillation, Pathophysiology, Electrocardiology (ECG), Magnetic Resonance Imaging (MRI), Ischemic Stroke Original Research Source Type: research

Left Atrial Appendage Closure Under Intracardiac Echocardiographic Guidance: Feasibility and Comparison With Transesophageal Echocardiography Interventional Cardiology
Conclusions Transcatheter left atrial appendage closure with intracardiac echocardiography guidance is safe and feasible.
Source: JAHA:Journal of the American Heart Association - September 27, 2016 Category: Cardiology Authors: Matsuo, Y., Neuzil, P., Petru, J., Chovanec, M., Janotka, M., Choudry, S., Skoda, J., Sediva, L., Kurabayashi, M., Reddy, V. Y. Tags: Atrial Fibrillation, Imaging, Ischemic Stroke, Thrombosis Interventional Cardiology Source Type: research

Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry Coronary Heart Disease
Conclusions Patients with stable coronary artery disease and angina have higher rates of future cardiovascular events compared with patients without angina. After adjustment, angina was only weakly associated with cardiovascular death, myocardial infarction, or stroke, but significantly associated with heart failure, cardiovascular hospitalization, and coronary revascularization.
Source: JAHA:Journal of the American Heart Association - September 27, 2016 Category: Cardiology Authors: Eisen, A., Bhatt, D. L., Steg, P. G., Eagle, K. A., Goto, S., Guo, J., Smith, S. C., Ohman, E. M., Scirica, B. M., the REACH Registry Investigators Tags: Myocardial Infarction, Angina, Coronary Artery Disease Coronary Heart Disease Source Type: research

Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study Health Services and Outcomes Research
ConclusionsPPIs did not significantly affect the MACE and bleeding risk associated with prasugrel use, relative to clopidogrel.Clinical Trial RegistrationURL: https://www.clinicaltrials.gov. Unique identifier: NCT01088503.
Source: JAHA:Journal of the American Heart Association - September 27, 2016 Category: Cardiology Authors: Jackson, L. R., Peterson, E. D., McCoy, L. A., Ju, C., Zettler, M., Baker, B. A., Messenger, J. C., Faries, D. E., Effron, M. B., Cohen, D. J., Wang, T. Y. Tags: Quality and Outcomes Original Research Source Type: research

Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry Coronary Heart Disease
BackgroundThe extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated.Methods and ResultsIncluded were outpatients with established coronary artery disease who were enrolled in the REACH registry and were followed for 4 years. Angina at baseline was defined as necessitating episodic or permanent antianginal treatment. The primary end point was the composite of cardiovascular death, myocardial infarction, or stroke. Secondary end points included heart failure, cardiovascular hospitalizations, and coronary revascularization. The independent associ...
Source: JAHA:Journal of the American Heart Association - September 27, 2016 Category: Cardiology Authors: Eisen, A., Bhatt, D. L., Steg, P. G., Eagle, K. A., Goto, S., Guo, J., Smith, S. C., Ohman, E. M., Scirica, B. M., the REACH Registry Investigators Tags: Myocardial Infarction, Angina, Coronary Artery Disease Original Research Source Type: research

Detection of Atrial Fibrillation Among Patients With Stroke Due to Large or Small Vessel Disease: A Meta-Analysis Stroke
ConclusionsAF detection rate is similar in patients with small and large vessel strokes (2.2–2.4%). Because no studies reported on extended monitoring (>7 days) in these stroke populations, we could not estimate the yield of AF detection with long‐term cardiac monitoring. Randomized controlled trials are needed to examine the utility of AF detection with long‐term cardiac monitoring (>7 days) in this patient population.
Source: JAHA:Journal of the American Heart Association - September 25, 2016 Category: Cardiology Authors: Demeestere, J., Fieuws, S., Lansberg, M. G., Lemmens, R. Tags: Atrial Fibrillation, Secondary Prevention, Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research

Trends in Transient Ischemic Attack Hospitalizations in the United States Epidemiology
ConclusionsAlthough overall TIA hospitalizations have decreased in the United States, the reduction has been more pronounced among older individuals, men, whites, and Hispanics. These findings highlight the need to target risk‐factor control among women, blacks, and individuals aged
Source: JAHA:Journal of the American Heart Association - September 23, 2016 Category: Cardiology Authors: Ramirez, L., Kim-Tenser, M. A., Sanossian, N., Cen, S., Wen, G., He, S., Mack, W. J., Towfighi, A. Tags: Epidemiology, Transient Ischemic Attack (TIA) Original Research Source Type: research

Ventricular-Arterial Function and Coupling in the Adult Fontan Circulation Congenital Heart Disease
BackgroundIn adult Fontan patients, ventricular or arterial dysfunction may impact homeostasis of the Fontan circulation and predispose to heart failure. We sought to characterize ventricular‐arterial (VA) properties in adult Fontan patients.Methods and ResultsAdult Fontan patients (n=170), including those with right (SRV, n=57) and left (SLV, n=113) dominant ventricular morphology, were compared to age, sex, and body size matched controls (n=170). Arterial function, load‐insensitive measures of contractility, VA coupling, diastolic function, and ventricular efficiency were assessed. Compared to controls, Fontan patien...
Source: JAHA:Journal of the American Heart Association - September 22, 2016 Category: Cardiology Authors: Saiki, H., Eidem, B. W., Ohtani, T., Grogan, M. A., Redfield, M. M. Tags: Congenital Heart Disease, Cardiovascular Surgery Original Research Source Type: research

Factors Associated With Initial Prasugrel Versus Clopidogrel Selection for Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention: Insights From the Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study Coronary Heart Disease
We examined patients presenting with acute myocardial infarction treated with percutaneous coronary intervention at 233 US hospitals in the TRANSLATE‐ACS observational study from April 2010 to October 2012. We developed a multivariable logistic regression model to identify factors associated with prasugrel selection. Prasugrel use rates and associated 1‐year risk‐adjusted major adverse cardiovascular events and Global Utilization of Streptokinase and t‐PA for Occluded Coronary Arteries (GUSTO) moderate/severe bleeding outcomes were also examined in relation to predicted mortality and bleeding using the validated Ac...
Source: JAHA:Journal of the American Heart Association - September 22, 2016 Category: Cardiology Authors: Vora, A. N., Peterson, E. D., McCoy, L. A., Effron, M. B., Anstrom, K. J., Faries, D. E., Zettler, M. E., Fonarow, G. C., Baker, B. A., Stone, G. W., Wang, T. Y. Tags: Acute Coronary Syndromes, Coronary Artery Disease Original Research Source Type: research

Ventricular-Arterial Function and Coupling in the Adult Fontan Circulation Congenital Heart Disease
Conclusions Adult Fontan patients have contractile and diastolic dysfunction with normal afterload, impaired VA coupling, and reduced ventricular efficiency with heightened sensitivity to heart rate. Maintenance of CI is dependent on lower afterload, eccentric remodeling, and relative preservation of diastolic function. These data contribute to our understanding of circulatory physiology in adult Fontan patients.
Source: JAHA:Journal of the American Heart Association - September 22, 2016 Category: Cardiology Authors: Saiki, H., Eidem, B. W., Ohtani, T., Grogan, M. A., Redfield, M. M. Tags: Congenital Heart Disease, Cardiovascular Surgery Source Type: research

Factors Associated With Initial Prasugrel Versus Clopidogrel Selection for Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention: Insights From the Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study Coronary Heart Disease
Conclusions In community practice, prasugrel use may be driven more by bleeding risk rather than ischemic benefit. This may result in underutilization of higher potency ADP receptor inhibitor among patients more likely to derive ischemic benefit.
Source: JAHA:Journal of the American Heart Association - September 22, 2016 Category: Cardiology Authors: Vora, A. N., Peterson, E. D., McCoy, L. A., Effron, M. B., Anstrom, K. J., Faries, D. E., Zettler, M. E., Fonarow, G. C., Baker, B. A., Stone, G. W., Wang, T. Y. Tags: Acute Coronary Syndromes, Coronary Artery Disease Coronary Heart Disease Source Type: research

Cerebral Microbleeds, Vascular Risk Factors, and Magnetic Resonance Imaging Markers: The Northern Manhattan Study Epidemiology
Conclusions CMBs may represent the severity of vascular disease in this racially and ethnically diverse cohort. Larger studies are needed to elucidate the association between diabetes medication use and CMB presence.
Source: JAHA:Journal of the American Heart Association - September 15, 2016 Category: Cardiology Authors: Caunca, M. R., Del Brutto, V., Gardener, H., Shah, N., Dequatre-Ponchelle, N., Cheung, Y. K., Elkind, M. S. V., Brown, T. R., Cordonnier, C., Sacco, R. L., Wright, C. B. Tags: Epidemiology, Race and Ethnicity Source Type: research