Source: JAHA:Journal of the American Heart Association
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Total 381 results found since Jan 2013.
Gastric Bypass Surgery Produces a Durable Reduction in Cardiovascular Disease Risk Factors and Reduces the Long-Term Risks of Congestive Heart Failure Preventive Cardiology
ConclusionsGastric bypass is associated with a reduced risk of major cardiovascular events and the development of congestive heart failure.
Source: JAHA:Journal of the American Heart Association - May 23, 2017 Category: Cardiology Authors: Benotti, P. N., Wood, G. C., Carey, D. J., Mehra, V. C., Mirshahi, T., Lent, M. R., Petrick, A. T., Still, C., Gerhard, G. S., Hirsch, A. G. Tags: Cardiomyopathy, Heart Failure, Metabolic Syndrome, Remodeling, Cerebrovascular Disease/Stroke Original Research Source Type: research
Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study Stroke
BackgroundThere is controversy surrounding the risk of ischemic stroke associated with the use of calcium supplements either in monotherapy or in combination with vitamin D.Methods and ResultsA nested case‐control study was performed with patients aged 40 to 89 years old, among whom a total of 2690 patients had a first episode of nonfatal ischemic stroke and for which 19 538 controls were randomly selected from the source population and frequency‐matched with cases for age, sex, and calendar year. Logistic regression provided the odds ratios while adjusting for confounding factors. A sensitivity analysis was performe...
Source: JAHA:Journal of the American Heart Association - May 18, 2017 Category: Cardiology Authors: de Abaȷo, F. J., Rodriguez-Martin, S., Rodriguez-Miguel, A., Gil, M. J. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research
Systolic Blood Pressure Within 24 Hours After Thrombectomy for Acute Ischemic Stroke Correlates With Outcome Stroke
ConclusionsHigher peak values of systolic blood pressure independently correlated with worse 90‐day modified Rankin scale and a higher rate of hemorrhagic complications. Further prospective studies are warranted to identify whether systolic blood pressure is a therapeutic target to improve outcomes.
Source: JAHA:Journal of the American Heart Association - May 18, 2017 Category: Cardiology Authors: Mistry, E. A., Mistry, A. M., Nakawah, M. O., Khattar, N. K., Fortuny, E. M., Cruz, A. S., Froehler, M. T., Chitale, R. V., James, R. F., Fusco, M. R., Volpi, J. J. Tags: High Blood Pressure, Revascularization, Complications, Quality and Outcomes, Ischemic Stroke Original Research Source Type: research
Race-Sex Differences in Statin Use and Low-Density Lipoprotein Cholesterol Control Among People With Diabetes Mellitus in the Reasons for Geographic and Racial Differences in Stroke Study Health Services and Outcomes Research
BackgroundStatin therapy is a cornerstone of cardiovascular disease risk reduction for people with diabetes mellitus. Past reports have shown race‐sex differences in statin use in general populations, but statin patterns by race and sex in those with diabetes mellitus have not been thoroughly studied.Methods and ResultsOur sample of 4288 adults ≥45 years of age with diagnosed diabetes mellitus who had low‐density lipoprotein cholesterol (LDL‐C)>100 mg/dL or were taking statins recruited for the Reasons for Geographic and Racial Differences in Stroke study from 2003 to 2007. Exposures included race‐sex groups (w...
Source: JAHA:Journal of the American Heart Association - May 10, 2017 Category: Cardiology Authors: Gamboa, C. M., Colantonio, L. D., Brown, T. M., Carson, A. P., Safford, M. M. Tags: Lipids and Cholesterol, Diabetes, Type 2, Epidemiology, Race and Ethnicity, Health Services Original Research Source Type: research
Observed Cost and Variations in Short Term Cost-Effectiveness of Therapy for Ischemic Stroke in Interventional Management of Stroke (IMS) III Health Services and Outcomes Research
ConclusionsDetailed economic and resource utilization data from IMS III provide powerful evidence for the large effect that patient outcome has on the economic value of medical and endovascular reperfusion therapies. These data can be used to inform process improvements for stroke care and to estimate the cost‐effectiveness of endovascular therapy in the US health system for stroke intervention trials.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Registration number: NCT00359424.
Source: JAHA:Journal of the American Heart Association - May 8, 2017 Category: Cardiology Authors: Simpson, K. N., Simpson, A. N., Mauldin, P. D., Palesch, Y. Y., Yeatts, S. D., Kleindorfer, D., Tomsick, T. A., Foster, L. D., Demchuk, A. M., Khatri, P., Hill, M. D., Jauch, E. C., Jovin, T. G., Yan, B., von Kummer, R., Molina, C. A., Goyal, M., Schonewi Tags: Cost-Effectiveness, Health Services, Cerebrovascular Procedures, Ischemic Stroke Original Research Source Type: research
Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype Stroke
BackgroundIschemic and hemorrhagic stroke are increasingly recognized as heterogeneous diseases with distinct subtypes and etiologies. Information on variation in distribution of vascular risk factors according to age in stroke subtypes is limited. We investigated the prevalence of vascular risk factors in stroke subtypes in relation to age.Methods and ResultsWe studied a prospective multicenter university hospital–based cohort of 4033 patients. For patients with ischemic stroke caused by large artery atherosclerosis, small vessel disease, or cardioembolism and for patients with spontaneous intracerebral hemorrhage or an...
Source: JAHA:Journal of the American Heart Association - May 8, 2017 Category: Cardiology Authors: Hauer, A. J., Ruigrok, Y. M., Algra, A., van Diȷk, E. J., Koudstaal, P. J., Luiȷckx, G.–J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., Kappelle, L. J., Kliȷn, C. J. M., the Dutch Parelsnoer Instit Tags: Risk Factors, Intracranial Hemorrhage, Ischemic Stroke Original Research Source Type: research
Long-Term Outcomes of Patients With Mediastinal Radiation-Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study Valvular Heart Disease
BackgroundCardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis. In patients with XRT‐induced severe aortic stenosis undergoing surgical aortic valve replacement (SAVR), we sought to: (1) study long‐term survival and compare these patients with a matched cohort undergoing SAVR during the same time frame; and (2) identify potential predictors of long‐term mortality.Methods and ResultsWe studied patients with symptomatic severe aortic stenosis undergoing SAVR at our institution, of which there were 172 mediastinal XRT patients (6...
Source: JAHA:Journal of the American Heart Association - May 5, 2017 Category: Cardiology Authors: Donnellan, E., Masri, A., Johnston, D. R., Pettersson, G. B., Rodriguez, L. L., Popovic, Z. B., Roselli, E. E., Smedira, N. G., Svensson, L. G., Griffin, B. P., Desai, M. Y. Tags: Valvular Heart Disease Original Research Source Type: research
Therapeutic Strategies and Drug Development for Vascular Cognitive Impairment Contemporary Review
Source: JAHA:Journal of the American Heart Association - May 5, 2017 Category: Cardiology Authors: Smith, E. E., Cieslak, A., Barber, P., Chen, J., Chen, Y.-W., Donnini, I., Edwards, J. D., Frayne, R., Field, T. S., Hegedus, J., Hanganu, V., Ismail, Z., Kanji, J., Nakajima, M., Noor, R., Peca, S., Sahlas, D., Sharma, M., Sposato, L. A., Swartz, R. H., Tags: Secondary Prevention, Cerebrovascular Disease/Stroke, Cognitive Impairment, Neuroprotectants Contemporary Review Source Type: research
Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study Epidemiology
ConclusionsThis study provides comprehensive estimates of PAD in the inpatient and outpatient settings where the majority of PAD burden was found. PAD is an important circulatory system disorder similar in prevalence to stroke and coronary heart disease.
Source: JAHA:Journal of the American Heart Association - May 3, 2017 Category: Cardiology Authors: Kalbaugh, C. A., Kucharska-Newton, A., Wruck, L., Lund, J. L., Selvin, E., Matsushita, K., Bengtson, L. G. S., Heiss, G., Loehr, L. Tags: Epidemiology, Peripheral Vascular Disease Original Research Source Type: research
Comparison of Expert Adjudicated Coronary Heart Disease and Cardiovascular Disease Mortality With the National Death Index: Results From the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Epidemiology
ConclusionsThe modest accuracy and differential performance of NDI‐derived cause of death may impact CHD and CVD mortality statistics.
Source: JAHA:Journal of the American Heart Association - May 3, 2017 Category: Cardiology Authors: Olubowale, O. T., Safford, M. M., Brown, T. M., Durant, R. W., Howard, V. J., Gamboa, C., Glasser, S. P., Rhodes, J. D., Levitan, E. B. Tags: Cardiovascular Disease, Epidemiology Original Research Source Type: research
Million Hearts: Description of the National Surveillance and Modeling Methodology Used to Monitor the Number of Cardiovascular Events Prevented During 2012-2016 Epidemiology
ConclusionsAround 115 000 events were prevented during the initiative's first 2 years compared with what would have occurred had 2011 rates remained stable. Recent flattening or reversals in some event rate trends were observed supporting intensifying national action to prevent cardiovascular events.
Source: JAHA:Journal of the American Heart Association - May 2, 2017 Category: Cardiology Authors: Ritchey, M. D., Loustalot, F., Wall, H. K., Steiner, C. A., Gillespie, C., George, M. G., Wright, J. S. Tags: Epidemiology, Myocardial Infarction, Mortality/Survival, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Research Source Type: research
Temporal Trends in Incidence, Prevalence, and Mortality of Atrial Fibrillation in Primary Care Epidemiology
BackgroundIncidence and prevalence of atrial fibrillation (AF) are expected to increase dramatically; however, we currently lack comprehensive data on temporal trends in unselected clinical populations.Methods and ResultsAnalysis of the UK Clinical Practice Research Datalink (CPRD) from 1998 to 2010 of patients with incident AF, excluding major valvular disease, linked to hospital admission data and national statistics. Fifty‐seven thousand eight hundred eighteen adults were identified with mean age 74.2 (SD, 11.7) years and 48.3% women. Overall age‐adjusted incidence of AF per 1000 person years was 1.11 (95% CI, 1.09...
Source: JAHA:Journal of the American Heart Association - April 28, 2017 Category: Cardiology Authors: Lane, D. A., Skȷoth, F., Lip, G. Y. H., Larsen, T. B., Kotecha, D. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Mortality/Survival, Quality and Outcomes Original Research Source Type: research
Marital History and Survival After Stroke Corrections
Source: JAHA:Journal of the American Heart Association - April 24, 2017 Category: Cardiology Tags: Correction Source Type: research
Comparative Effectiveness and Safety of Dabigatran and Rivaroxaban in Atrial Fibrillation Patients Arrhythmia and Electrophysiology
ConclusionsRivaroxaban therapy was associated with a statistically significant increase in all‐cause death compared with dabigatran therapy in atrial fibrillation patients.
Source: JAHA:Journal of the American Heart Association - April 24, 2017 Category: Cardiology Authors: Lai, C.-L., Chen, H.-M., Liao, M.-T., Lin, T.-T., Chan, K. A. Tags: Arrhythmias, Anticoagulants, Pharmacology, Cerebrovascular Disease/Stroke Original Research Source Type: research
Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection Coronary Heart Disease
ConclusionsAn integrated collection of end points and serious AEs is feasible in a multinational trial and illustrates the shared characteristics of events. Tailoring event collection to fit the phase and purpose of the trial is achievable and informative.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00831441.
Source: JAHA:Journal of the American Heart Association - April 24, 2017 Category: Cardiology Authors: Guimaraes, P. O., Lopes, R. D., Stevens, S. R., Zimerman, A., Wruck, L., James, S. K., Haque, G., Giraldez, R. R. C. V., Alexander, J. H., Alexander, K. P. Tags: Clinical Studies, Cardiovascular Disease, Myocardial Infarction, Acute Coronary Syndromes Original Research Source Type: research