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Source: JAHA:Journal of the American Heart Association

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Total 381 results found since Jan 2013.

Seeking Culprit Lesions in Cryptogenic Stroke: The Utility of Vessel Wall Imaging Editorials
Source: JAHA:Journal of the American Heart Association - June 15, 2015 Category: Cardiology Authors: Sun, J., Yuan, C. Tags: Editorials Source Type: research

Traditional Risk Factors Versus Biomarkers for Prediction of Secondary Events in Patients With Stable Coronary Heart Disease: From the Heart and Soul Study Coronary Heart Disease
Conclusions Novel risk factors are superior to traditional risk factors for predicting 5-year risk of secondary events in patients with stable CHD.
Source: JAHA:Journal of the American Heart Association - July 6, 2015 Category: Cardiology Authors: Beatty, A. L., Ku, I. A., Bibbins-Domingo, K., Christenson, R. H., DeFilippi, C. R., Ganz, P., Ix, J. H., Lloyd-Jones, D., Omland, T., Sabatine, M. S., Schiller, N. B., Shlipak, M. G., Skali, H., Takeuchi, M., Vittinghoff, E., Whooley, M. A. Tags: Coronary Heart Disease Source Type: research

Association of 6-Minute Walk Performance and Physical Activity With Incident Ischemic Heart Disease Events and Stroke in Peripheral Artery Disease Vascular Medicine
Conclusions Six-minute walk and physical activity predict IHD event rates in PAD. Further study is needed to determine whether interventions that improve 6-minute walk, physical activity, or both can reduce IHD events in PAD.
Source: JAHA:Journal of the American Heart Association - July 28, 2015 Category: Cardiology Authors: McDermott, M. M., Greenland, P., Tian, L., Kibbe, M. R., Green, D., Zhao, L., Criqui, M. H., Guralnik, J. M., Ferrucci, L., Liu, K., Wilkins, J. T., Huffman, M. D., Shah, S. J., Liao, Y., Lloyd-Jones, D. M. Tags: Vascular Medicine Source Type: research

Risk of Incident Coronary Heart Disease Events in Men Compared to Women by Menopause Type and Race Epidemiology
Conclusions Sex differences in the risk of incident CHD events were larger among whites than blacks and varied by type of menopause. Women consistently had a lower risk of incident CHD death than men, but the magnitude of sex differences was greater in whites than blacks for nonfatal events, regardless of menopause type.
Source: JAHA:Journal of the American Heart Association - July 1, 2015 Category: Cardiology Authors: Kim, C., Cushman, M., Khodneva, Y., Lisabeth, L. D., Judd, S., Kleindorfer, D. O., Howard, V. J., Safford, M. M. Tags: Epidemiology Source Type: research

Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke? Contemporary Reviews
Source: JAHA:Journal of the American Heart Association - August 3, 2015 Category: Cardiology Authors: Cao, L., Pokorney, S. D., Hayden, K., Welsh-Bohmer, K., Newby, L. K. Tags: Contemporary Reviews Source Type: research

Outcome Reporting in Cardiac Surgery Trials: Systematic Review and Critical Appraisal Cardiovascular Surgery
Conclusions Outcome reporting in the cardiac surgery literature is heterogeneous, and efforts should be made to standardize the outcomes reported and the definitions used to ascertain them. The development of standardizing outcome reporting is an essential step toward strengthening the process of evidence-based care in cardiac surgery.
Source: JAHA:Journal of the American Heart Association - August 17, 2015 Category: Cardiology Authors: Goldfarb, M., Drudi, L., Almohammadi, M., Langlois, Y., Noiseux, N., Perrault, L., Piazza, N., Afilalo, J. Tags: Cardiovascular Surgery Source Type: research

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation Valvular Heart Disease
Conclusions MHV induce thrombin generation via the intrinsic pathway and generate sufficient thrombin to overwhelm clinically relevant dabigatran concentrations. In contrast, warfarin is more effective than dabigatran at suppressing MHV-induced thrombin generation. These data explain why dabigatran failed in MHV patients and suggest that strategies targeting FXII or FXI may suppress the root cause of thrombosis in such patients.
Source: JAHA:Journal of the American Heart Association - August 24, 2015 Category: Cardiology Authors: Jaffer, I. H., Stafford, A. R., Fredenburgh, J. C., Whitlock, R. P., Chan, N. C., Weitz, J. I. Tags: Valvular Heart Disease Source Type: research

Left Ventricular Structure and Risk of Cardiovascular Events: A Framingham Heart Study Cardiac Magnetic Resonance Study Epidemiology
Conclusions Among adults free of prevalent CVD in the community, greater LVMI and LV concentric hypertrophy are associated with a marked increase in adverse incident CVD events. The potential benefit of aggressive primary prevention to modify LV mass and geometry in these adults requires further investigation.
Source: JAHA:Journal of the American Heart Association - September 15, 2015 Category: Cardiology Authors: Tsao, C. W., Gona, P. N., Salton, C. J., Chuang, M. L., Levy, D., Manning, W. J., O'Donnell, C. J. Tags: Epidemiology Source Type: research

Long-Term Prognostic Risk in Lower Extremity Peripheral Arterial Disease as a Function of the Number of Peripheral Arterial Lesions Health Services and Outcomes Research
Conclusions Among PAD patients, a greater number of lesions is associated with an increased risk of an adverse prognosis over 3 years of follow-up. Assessing the number of lower extremity lesions might serve as a simple risk-stratification tool at initial PAD diagnosis.
Source: JAHA:Journal of the American Heart Association - October 26, 2015 Category: Cardiology Authors: Smolderen, K. G., van Zitteren, M., Jones, P. G., Spertus, J. A., Heyligers, J. M., Nooren, M. J., Vriens, P. W., Denollet, J. Tags: Health Services and Outcomes Research Source Type: research

Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes and Chronic Obstructive Pulmonary Disease: An Analysis From the Platelet Inhibition and Patient Outcomes (PLATO) Trial Coronary Heart Disease
Conclusions In this post-hoc analysis, COPD patients experienced high rates of ischemic events. Ticagrelor versus clopidogrel reduced and substantially decreased the absolute risk of ischemic events (5.8%) in COPD patients, without increasing overall major bleeding events. The benefit-risk profile supports the use of ticagrelor in patients with ACS and concomitant COPD. Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT00391872.
Source: JAHA:Journal of the American Heart Association - October 9, 2015 Category: Cardiology Authors: Andell, P., James, S. K., Cannon, C. P., Cyr, D. D., Himmelmann, A., Husted, S., Keltai, M., Koul, S., Santoso, A., Steg, P. G., Storey, R. F., Wallentin, L., Erlinge, D., the PLATO Investigators Tags: Coronary Heart Disease Source Type: research

Individual Proton Pump Inhibitors and Outcomes in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy: A Systematic Review Coronary Heart Disease
Conclusions Several frequently used PPIs previously thought to be safe for concomitant use with clopidogrel were associated with greater risk of adverse cardiovascular events. Although the data are observational, they highlight the need for randomized controlled trials to evaluate the safety of concomitant PPI and clopidogrel use in patients with coronary artery disease.
Source: JAHA:Journal of the American Heart Association - October 29, 2015 Category: Cardiology Authors: Sherwood, M. W., Melloni, C., Jones, W. S., Washam, J. B., Hasselblad, V., Dolor, R. J. Tags: Coronary Heart Disease Source Type: research

N-glycome Profile Levels Relate to Silent Brain Infarcts in a Cohort of Hypertensives Imaging
Conclusions N-glycome levels might be potentially useful as biomarkers for the presence of silent cerebrovascular disease.
Source: JAHA:Journal of the American Heart Association - November 23, 2015 Category: Cardiology Authors: Vilar-Bergua, A., Riba-Llena, I., Vanhooren, V., Dewaele, S., Libert, C., Penalba, A., Montaner, J., Delgado, P. Tags: Imaging Source Type: research

Effect Modification of Long-Term Air Pollution Exposures and the Risk of Incident Cardiovascular Disease in US Women Epidemiology
Conclusions In this nationwide cohort, women with diabetes were identified as the subpopulation most sensitive to the adverse cardiovascular health effects of PM.
Source: JAHA:Journal of the American Heart Association - November 25, 2015 Category: Cardiology Authors: Hart, J. E., Puett, R. C., Rexrode, K. M., Albert, C. M., Laden, F. Tags: Epidemiology Source Type: research

Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure Congenital Heart Disease
Conclusions The neuropsychological deficits and high frequencies of structural brain abnormalities in adolescents who underwent the Fontan procedure highlight the need for research on interventions to improve the long-term outcomes in this high-risk group.
Source: JAHA:Journal of the American Heart Association - December 14, 2015 Category: Cardiology Authors: Bellinger, D. C., Watson, C. G., Rivkin, M. J., Robertson, R. L., Roberts, A. E., Stopp, C., Dunbar-Masterson, C., Bernson, D., DeMaso, D. R., Wypij, D., Newburger, J. W. Tags: Congenital Heart Disease Source Type: research

Population Trends in Aspirin Use for Cardiovascular Disease Prevention 1980-2009: The Minnesota Heart Survey Preventive Cardiology
Conclusions Aspirin for CVD prevention is commonly used by a large and growing portion of the general population. It is not known if this is based on professional advice or self-prescribed use. It is also likely that many who would benefit do not use aspirin and others use aspirin inappropriately.
Source: JAHA:Journal of the American Heart Association - December 23, 2015 Category: Cardiology Authors: Luepker, R. V., Steffen, L. M., Duval, S., Zantek, N. D., Zhou, X., Hirsch, A. T. Tags: Preventive Cardiology Source Type: research