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Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study Stroke
Conclusions Our data provide strong support for future studies on the role of PTCSC3 in the pathogenesis of LAA stroke and the association between LAA stroke development and thyroid function. In addition, these findings provide insights into the genetic basis of LAA stroke and identify a novel pathway that might be applicable for future therapeutic intervention.
Source: JAHA:Journal of the American Heart Association - March 28, 2016 Category: Cardiology Authors: Lee, T.-H., Ko, T.-M., Chen, C.-H., Lee, M.-T. M., Chang, Y.-J., Chang, C.-H., Huang, K.-L., Chang, T.-Y., Lee, J.-D., Chang, K.-C., Yang, J.-T., Wen, M.-S., Wang, C.-Y., Chen, Y.-T., Hsieh, C.-S., Chou, S.-Y., Liu, Y.-M., Chen, H.-W., Liao, H.-T., Wang, Tags: Genetic, Association Studies, Ischemic Stroke Source Type: research