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Source: JAHA:Journal of the American Heart Association
Condition: Stroke
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Total 368 results found since Jan 2013.
Incidence of First Stroke in Pregnant and Nonpregnant Women of Childbearing Age: A Population-Based Cohort Study From England Epidemiology
ConclusionsAlthough the absolute risk of first stroke is low in women of childbearing age, healthcare professionals should be aware of a considerable increase in relative risk during the peripartum and early postpartum periods.
Source: JAHA:Journal of the American Heart Association - April 21, 2017 Category: Cardiology Authors: Ban, L., Sprigg, N., Abdul Sultan, A., Nelson-Piercy, C., Bath, P. M., Ludvigsson, J. F., Stephansson, O., Tata, L. J. Tags: Epidemiology, Pregnancy, Women, Cerebrovascular Disease/Stroke Original Research Source Type: research
Association of Magnet Status With Hospitalization Outcomes for Ischemic Stroke Patients Health Services and Outcomes Research
ConclusionsUsing a comprehensive all‐payer cohort of patients with ischemic stroke in New York State, we identified an association of treatment in Magnet hospitals with lower case‐fatality, discharge to a facility, and length of stay. Further research into the factors contributing to the superiority of Magnet hospitals in stroke care is warranted.
Source: JAHA:Journal of the American Heart Association - April 18, 2017 Category: Cardiology Authors: Bekelis, K., Missios, S., MacKenzie, T. A. Tags: Epidemiology, Cost-Effectiveness, Ethics and Policy, Health Services, Quality and Outcomes Original Research Source Type: research
Health Literacy and Awareness of Atrial Fibrillation Arrhythmia and Electrophysiology
ConclusionsLower health literacy is independently associated with less awareness of AF diagnosis. Strategies designed to increase patient awareness of AF and its complications are warranted among individuals with limited health literacy.
Source: JAHA:Journal of the American Heart Association - April 11, 2017 Category: Cardiology Authors: Reading, S. R., Go, A. S., Fang, M. C., Singer, D. E., Liu, I.–L. A., Black, M. H., Udaltsova, N., Reynolds, K., the Anticoagulation and Risk Factors in Atrial Fibrillation-Cardiovascular Research Network (ATRIA-CVRN) Investigators Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Health Services Original Research Source Type: research
Relationship Between Peak Troponin Values and Long-Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes Coronary Heart Disease
BackgroundThe relationship between troponin level and outcomes among patients with non‐ST‐segment elevation ACS is established, but the relationship of troponin level with long‐term outcomes among medically managed non‐ST‐segment elevation ACS patients receiving contemporary antiplatelet therapy is inadequately defined.Methods and ResultsIn 6763 medically managed non‐ST‐segment elevation ACS patients randomized in TRILOGY ACS (Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes) (prasugrel versus clopidogrel), we examined relationships between categories o...
Source: JAHA:Journal of the American Heart Association - April 11, 2017 Category: Cardiology Authors: Goldstein, S. A., Newby, L. K., Cyr, D. D., Neely, M., Luscher, T. F., Brown, E. B., White, H. D., Ohman, E. M., Roe, M. T., Hamm, C. W. Tags: Acute Coronary Syndromes Original Research Source Type: research
Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study Genetics
ConclusionsFuture studies are needed to replicate and/or determine the causal variants driving our associations and explore clinical applications for those consistently associated with CVEs.
Source: JAHA:Journal of the American Heart Association - April 10, 2017 Category: Cardiology Authors: Shendre, A., Irvin, M. R., Wiener, H., Zhi, D., Limdi, N. A., Overton, E. T., Shrestha, S. Tags: Cardiovascular Disease, Epidemiology, Race and Ethnicity, Risk Factors, Heart Failure Original Research Source Type: research
Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice Stroke
ConclusionsWe conclude that brain ischemia induces the formation of β‐hydroxybutyrate (ketogenesis) in the liver and the consumption of β‐hydroxybutyrate in the brain. This effect seems to be mediated by β‐adrenergic receptors.
Source: JAHA:Journal of the American Heart Association - April 5, 2017 Category: Cardiology Authors: Koch, K., Berressem, D., Konietzka, J., Thinnes, A., Eckert, G. P., Klein, J. Tags: Ischemia, Metabolism, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research
History of Periodontitis Diagnosis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality in Postmenopausal Women Epidemiology
BackgroundFew studies have reported associations between periodontitis and cardiovascular disease (CVD) risk in older women, which is the objective of the present investigation.Methods and ResultsParticipants were 57 001 postmenopausal women ages 55 to 89 years (mean 68 years;>85% 60 and older) who were enrolled (1993–1998) in the Women's Health Initiative Observational Study, and were without known CVD when history of periodontitis and edentulism was assessed by questionnaire at study Year‐5 (1998–2003). There were 3589 incident CVD events and 3816 total deaths during a mean follow‐up of 6.7 years. In multivar...
Source: JAHA:Journal of the American Heart Association - March 29, 2017 Category: Cardiology Authors: LaMonte, M. J., Genco, R. J., Hovey, K. M., Wallace, R. B., Freudenheim, J. L., Michaud, D. S., Mai, X., Tinker, L. F., Salazar, C. R., Andrews, C. A., Li, W., Eaton, C. B., Martin, L. W., Wactawski-Wende, J. Tags: Aging, Cardiovascular Disease, Epidemiology, Women, Mortality/Survival Original Research Source Type: research
Sex–Specific Relationship Between Serum Uric Acid and Risk of Stroke: A Dose–Response Meta–Analysis of Prospective Studies Systematic Review and Meta-Analysis
BackgroundConflicting findings of the association between serum uric acid (UA) and stroke have been reported in both men and women, and it is unclear whether this association was different between men and women. We preformed this meta‐analysis to assess the sex‐specific effect of serum UA on the risk of stroke and its subtypes.Methods and ResultsProspective studies that reported sex‐specific association of UA levels with stroke or reported in a certain sex were included. Dose‐response relationships were assessed by the generalized least squares trend estimation, and summary effect estimates were evaluated with rand...
Source: JAHA:Journal of the American Heart Association - March 29, 2017 Category: Cardiology Authors: Zhong, C., Zhong, X., Xu, T., , Zhang, Y. Tags: Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Systematic Review and Meta ‐ Analysis Source Type: research
Association of Cardiovascular Health With Subclinical Disease and Incident Events: The Multi-Ethnic Study of Atherosclerosis Epidemiology
ConclusionsThere is a graded inverse association between CVH scores and measures of subclinical and overt cardiovascular disease that is similar across race/ethnic groups.
Source: JAHA:Journal of the American Heart Association - March 20, 2017 Category: Cardiology Authors: Polonsky, T. S., Ning, H., Daviglus, M. L., Liu, K., Burke, G. L., Cushman, M., Eng, J., Folsom, A. R., Lutsey, P. L., Nettleton, J. A., Post, W. S., Sacco, R. L., Szklo, M., Lloyd-Jones, D. M. Tags: Epidemiology, Lifestyle, Primary Prevention, Race and Ethnicity, Vascular Disease Original Research Source Type: research
Sex Differences in Percutaneous Coronary Intervention—Insights From the Coronary Angiography and PCI Registry of the German Society of Cardiology Coronary Heart Disease
ConclusionsDespite identical technical success rates of PCI between the 2 sexes, women with PCI for ST elevation myocardial infarction have a 20% higher age‐adjusted risk of death and of ischemic cardiac and cerebrovascular events. Further research is needed to determine the reasons for these differences.
Source: JAHA:Journal of the American Heart Association - March 20, 2017 Category: Cardiology Authors: Heer, T., Hochadel, M., Schmidt, K., Mehilli, J., Zahn, R., Kuck, K.–H., Hamm, C., Bohm, M., Ertl, G., Hoffmeister, H. M., Sack, S., Senges, J., Massberg, S., Gitt, A. K., Zeymer, U. Tags: Cardiovascular Disease, Women, Percutaneous Coronary Intervention, Stent, Treatment Original Research Source Type: research
Performance of the Atherosclerotic Cardiovascular Disease Pooled Cohort Risk Equations by Social Deprivation Status Epidemiology
BackgroundThe atherosclerosis cardiovascular disease (ASCVD) Pooled Cohort risk equations have shown different calibration across US populations with varied levels of social deprivation.Methods and ResultsWe analyzed the calibration and discrimination of the Pooled Cohort risk equations by social deprivation status among 9066 REGARDS (REasons for Geographic And Racial Differences in Stroke) study participants not taking statins for whom ASCVD risk may lead to statin initiation. Patients were aged 45 to 79 years, had no ASCVD or diabetes mellitus, and had a low‐density lipoprotein cholesterol level 70 to 189 mg/dL. Soci...
Source: JAHA:Journal of the American Heart Association - March 17, 2017 Category: Cardiology Authors: Colantonio, L. D., Richman, J. S., Carson, A. P., Lloyd-Jones, D. M., Howard, G., Deng, L., Howard, V. J., Safford, M. M., Muntner, P., Goff, D. C. Tags: Cardiovascular Disease, Epidemiology, Lifestyle, Primary Prevention, Risk Factors Original Research Source Type: research
China Stroke Primary Prevention Trial: Visit-to-Visit Systolic Blood Pressure Variability Is an Independent Predictor of Primary Stroke in Hypertensive Patients Stroke
ConclusionsVisit‐to‐visit SBP variability is an independent predictor of primary stroke in Chinese hypertensive patients. This predictive value depends on the number of blood pressure measurements used to calculate variability but is independent of mean SBP.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT00794885.
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Men, X., Sun, W., Fan, F., Zhao, M., Huang, X., Wang, Y., Liu, L., Liu, R., , Peng, Q., Qin, X., Tang, G., Li, J., Zhang, Y., Cai, Y., Hou, F. F., Wang, B., Xu, X., Cheng, X., Sun, N., Huang, Y., Huo, Y. Tags: Epidemiology, Hypertension, Cerebrovascular Disease/Stroke Original Research Source Type: research
Risk of Inhospital Stroke or Death Is Associated With Age But Not Sex in Patients Treated With Carotid Endarterectomy for Asymptomatic or Symptomatic Stenosis in Routine Practice: Secondary Data Analysis of the Nationwide German Statutory Quality Assurance Database From 2009 to 2014 Cardiovascular Surgery
ConclusionsThis study shows that increasing age, but not sex, is associated with a higher risk of in‐hospital stroke or death following carotid endarterectomy under everyday conditions in Germany. Whereas the risk of death (alone) is significantly associated with age, the association between age and the risk of stroke (alone) can be considered of minor importance.
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Schmid, S., Tsantilas, P., Knappich, C., Kallmayer, M., Konig, T., Breitkreuz, T., Zimmermann, A., Kuehnl, A., Eckstein, H.–H. Tags: Aging, Women, Cardiovascular Surgery, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Research Source Type: research
Prediction of Cardiovascular Disease by the Framingham-REGICOR Equation in the High-Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata Epidemiology
ConclusionsIncident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non–high‐risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD independent of baseline risk.Clinical Trial Registration URL: http://www.Controlled-trials.com. Unique identifier: ISRCTN35739639.
Source: JAHA:Journal of the American Heart Association - March 13, 2017 Category: Cardiology Authors: Amor, A. J., Serra-Mir, M., Martinez-Gonzalez, M. A., Corella, D., Salas-Salvado, J., Fito, M., Estruch, R., Serra-Maȷem, L., Aros, F., Babio, N., Ros, E., Ortega, E., the PREDIMED Investigators
Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Lifestyle, Primary Prevention Original Research Source Type: research
Impact of Achieved Blood Pressure on First Stroke in Uncomplicated Grade 1 Hypertension Cardiovascular Surgery
BackgroundWe aimed to test the impact of achieved blood pressure (BP) on first stroke among patients with grade 1 hypertension and without cardiovascular diseases in the China Stroke Primary Prevention Trial.Methods and ResultsA total of 3187 patients with uncomplicated grade 1 hypertension were included. The risk of outcomes was assessed according to: (1) the proportion of visits in which BP was reduced to
Source: JAHA:Journal of the American Heart Association - March 8, 2017 Category: Cardiology Authors: Qin, X., Li, Y., Sun, N., He, M., Tang, G., Yin, D., Wang, J., Liang, M., Wang, B., Huo, Y., Xu, X., , Hou, F. F. Tags: Primary Prevention, High Blood Pressure, Cerebrovascular Disease/Stroke Original Research Source Type: research
