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Source: Journal of Stroke and Cerebrovascular Diseases

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In Reply to the Letter to the Editor Regarding "A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?"
We are grateful to Josef Finsterer for his comments on our recent case regarding the possible association of maternal COVID-19 infection during pregnancy with a neonatal case of intrauterine cerebral sinus venous thrombosis (CSVT). In the letter to editor, he had raised several arguments against a causal relationship, however our case report focused on the plausability of maternal COVID-19 infection as a triggering factor for in utero onset of CVST.
Source: Journal of Stroke and Cerebrovascular Diseases - March 6, 2023 Category: Neurology Authors: Dr Mine Ozdil, Dr İpek Dokurel Cetin Tags: Letter to the Editor Source Type: research

Outcomes and predictors of periprocedural stroke after transcatheter aortic valve implantation
Risk factors for stroke after transcatheter aortic valve implantation (TAVI) are currently incompletely understood.
Source: Journal of Stroke and Cerebrovascular Diseases - March 6, 2023 Category: Neurology Authors: Alexandra Castelo, Andr é Grazina, Bárbara Teixeira, Tiago Mendonça, Inês Rodrigues, Pedro Garcia Brás, Vera Vaz Ferreira, Rúben Ramos, António Fiarresga, Duarte Cacela, Rui Cruz Ferreira Source Type: research

Elevated HMGB1 and sRAGE levels in cerebrospinal fluid of aneurysmal subarachnoid hemorrhage patients
Neuroinflammation after aneurysmal subarachnoid hemorrhage (aSAH) leads to poor outcome of patients. High mobility group box 1 (HMGB1) contributes to inflammation through binding to receptors for advanced glycation end-products (RAGE) in various diseases. We aimed to determine the production of these two factors after aSAH and their relationship with clinical features.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2023 Category: Neurology Authors: Xue-Hong Chu, Hui-Yu Hu, Ivan Steve Godje Godje, Li-Juan Zhu, Jia-Bao Zhu, Yong-Liang Feng, Hai Wang, Yi-Bo Zhang, Juan Huang, Xin-Gang Sun Source Type: research

Vertebrobasilar dolichoectasia and other arterial abnormalities leading to abducens nerve palsy
Dolichoectatic vessels can cause cranial nerve dysfunction by either direct compression or ischemia. Abducens nerve palsy due to neurovascular compression by elongated, enlarged, tortuous or dilated arteries is an uncommon but important cause.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2023 Category: Neurology Authors: Aishwarya Aggarwal, Gagan Kalra, Louis R. Caplan Tags: Short Communication Source Type: research

ASOC Osuntokun Award Lecture 2022: Partnership for stroke prevention and treatment in Africa: Qualitative research processes and findings
Africa has one of the highest rates of stroke and stroke deaths in the world. The burden of stroke is increasing with a 3-year mortality rate of up to 84%. Stroke disproportionately affects the young and middle-aged population contributing to morbidity and mortality affecting families, communities, health systems, and economic progress. My objectives of the 2022 Osuntokun Award Lecture at the African Stroke Organization Conference were to explore our qualitative research findings from our communities and to propose future qualitative methods for improving stroke outcomes in Africa.
Source: Journal of Stroke and Cerebrovascular Diseases - March 2, 2023 Category: Neurology Authors: Carolyn Jenkins Source Type: research

Extra-criteria antiphospholipid antibodies in patients with small vessel brain lesions and clinical manifestations associated with antiphospholipid syndrome
Antiphospholipid syndrome (APS) – as included in the updated APS classification criteria – is characterized by circulating antibodies (Abs) directed against phospholipid-binding proteins or their complex with phospholipids (aPL) and clinical manifestations of thrombosis or gestational morbidity.1 These criteria are very specif ic to ensure homogeneity for some purposes, such as clinical assays, yet they are not very sensitive for APS diagnosis.2 Due to this lack of sensitivity, clinicians must be aware of some entities – distinct from thrombosis fetal losses, or eclampsia – that are not included in the classificati...
Source: Journal of Stroke and Cerebrovascular Diseases - February 24, 2023 Category: Neurology Authors: Miguel Ángel Estévez, Nallibe Lanio, Águeda Molina, Maria Reyes Jiménez-León, María José Picado, Eva Esteban, Sonia Sánchez, Lucio Pallarés, Maria Rosa Julià Source Type: research

Household income is associated with functional outcomes in a multi-institutional cohort of patients with ischemic stroke and COVID-19
We examined whether household income is associated with functional outcomes after stroke and COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2023 Category: Neurology Authors: Brian Stamm, Regina Royan, Gabriela Trifan, Ronald Alvaredo-Dyer, Faddi G. Saleh Velez, William Taylor, Pranusha Pinna, Nicholas J. Reish, Alejandro Vargas, Fernando D. Goldenberg, Michael J Schneck, Jos é Biller, Fernando Testai, Fan Z. Caprio, Sherry H Source Type: research

Validity of stroke severity assessment using medical records in a population-based cohort
Initial stroke severity is an important prognostic factor for outcome after acute stroke, in terms of functional dependency, post-stroke dementia, and mortality.1,2 Whilst the majority of stroke patients who are admitted to the hospital with stroke have substantial neurological deficits, over half of all strokes that occur in the population qualify as minor stroke,3 and are managed often in outpatient care.4 Given the important differences between minor and major stroke in prognosis and management, it is important to distinguish patients on the basis of stroke severity, but assessment outside of specialised stroke centres ...
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2023 Category: Neurology Authors: Jacqueline J. Claus, Brian B.P. Berghout, M. Kamran Ikram, Frank J. Wolters Source Type: research

Less is more - The Finnish Prehospital Stroke Scale prospective validation
The current bifurcation of the acute stroke care pathway requires prehospital separation of strokes caused by large vessel occlusion. The first four binary items of the Finnish Prehospital Stroke Scale (FPSS) identify stroke in general, while the fifth binary item alone identifies stroke due to large vessel occlusion. The straightforward design is both easy for paramedics and statistically beneficial. We implemented FPSS based Western Finland Stroke Triage Plan, including medical districts of a comprehensive stroke center and four primary stroke centers.
Source: Journal of Stroke and Cerebrovascular Diseases - February 16, 2023 Category: Neurology Authors: Jyrki Ollikainen, Pasi Jolma, Juha-Pekka Pienim äki, Pauli Vuorinen, Niku Oksala, Marko Kimpimäki, Markku Grönroos, Tuuli-Maria Haula, Heikki Janhunen, Satu-Liisa Pauniaho Source Type: research

Real-time feedback on mobile application use for emergency management affects the door-to-needle time and functional outcomes in acute ischemic stroke
Time from onset to reperfusion affects mortality and favorable outcomes in patients with acute ischemic stroke (AIS). To evaluate effects of a real-time feedback mobile application on critical time intervals and functional outcomes in stroke emergency management.
Source: Journal of Stroke and Cerebrovascular Diseases - February 14, 2023 Category: Neurology Authors: Hailili Reziya, Kadeer Sayifujiamali, Hai-Ji Han, Xi-Ming Wang, Tusun Nuerbiya, Damaola Nuerdong, Qiang Sang, Yan-Feng Wu Source Type: research

Association of elevated neutrophil-to-lymphocyte ratio with increased intracranial aneurysm stability scores and aneurysm growth
This study was performed to assess the association of the NLR with IAs stability.
Source: Journal of Stroke and Cerebrovascular Diseases - February 11, 2023 Category: Neurology Authors: Baorui Zhang, Yongkai Qin, Shangfeng Zhao, Wei Wang, Lang Liu, Siyuan Dong, Yan Miao, Songfeng Zhao, Zhongxue Wu, Jun Kang, Aihua Liu Source Type: research

Circulating macrophage colony-stimulating factor levels and stroke: A Mendelian randomization study
Colony-stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor, has been shown to be associated with risk of ischemic stroke in conventional epidemiological study. We performed a Mendelian randomization analysis to evaluate the effects of genetically predicted circulating CSF1 levels on stroke and carotid intima-media thickness (cIMT).
Source: Journal of Stroke and Cerebrovascular Diseases - February 11, 2023 Category: Neurology Authors: Liping Cao, Dandan Liu, Ville Karhunen, Yi Ren, Dan Ye, Jie Gao, Dipender Gill, Mengmeng Wang Source Type: research

Genetic variants in the promoters of let-7 are associated with the risk and age at onset of ischemic stroke: A case control study
Stroke is China's main cause of mortality and years of life lost. With the aging population and increasing urbanization, stroke incidence has risen in China.1 Ischemic stroke (IS) is a multifactorial and multigenic disease that develops when blood supply to a specific part of the brain is disrupted or diminished, generally due to a thrombus. Although there are advancements in recanalization therapy, treatment options for stroke are still limited.2 Identifying genetic variants related to the onset risk of IS could contribute to understanding its pathogenesis and further developing innovative strategies for managing and prev...
Source: Journal of Stroke and Cerebrovascular Diseases - February 11, 2023 Category: Neurology Authors: Yuye Wang, Luying Qiu, Wenjuan Jiang, Meilin Chen, Zhiyi He, Yanzhe Wang, Shumin Deng Source Type: research

Table of Contents
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2023 Category: Neurology Source Type: research

Editorial Board
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2023 Category: Neurology Source Type: research