Query: stroke

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Source: Journal of Neurosurgery

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Total 168 results found since Jan 2013.

Soluble receptor for advanced glycation end products as a biomarker of symptomatic vasospasm in subarachnoid hemorrhage.
CONCLUSIONS: Plasma sRAGE levels can be used as a potential biomarker for predicting SVS after SAH. PMID: 31675694 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 1, 2019 Category: Neurosurgery Authors: Aida Y, Kamide T, Ishii H, Kitao Y, Uchiyama N, Nakada M, Hori O Tags: J Neurosurg Source Type: research

Multimodal cerebral arteriovenous malformation treatment: a 12-year experience and comparison of key outcomes to ARUBA.
CONCLUSIONS: This multimodal approach to the selection and treatment of patients with brain AVMs yields good clinical outcomes with key safety endpoints (stroke, death, and mRS score 0-1) better than the ARUBA intervention arm and similar to the ARUBA medical arm at 5 years of follow-up. Results compare favorably to natural history cohorts at longer follow-up times. This suggests that tertiary care centers with integrated programs, expertise in patient selection, and individualized treatment approaches may allow for better clinical outcomes than reported in ARUBA. It supports current registry studies and merits considerati...
Source: Journal of Neurosurgery - November 1, 2019 Category: Neurosurgery Authors: Pulli B, Chapman PH, Ogilvy CS, Patel AB, Stapleton CJ, Leslie-Mazwi TM, Hirsch JA, Carter BS, Rabinov JD Tags: J Neurosurg Source Type: research

Risk of internal carotid artery stenosis or occlusion after single-fraction radiosurgery for benign parasellar tumors.
CONCLUSIONS: New or progressive ICA stenosis/occlusion was common after SRS for CSM but was not observed after SRS for GHPA, suggesting a tumor-specific mechanism unrelated to radiation dose. Pre-SRS ICA encasement or constriction increases the risk of ICA stenosis/occlusion; however, the risk of ischemic complications is very low. PMID: 31653808 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 25, 2019 Category: Neurosurgery Authors: Graffeo CS, Link MJ, Stafford SL, Parney IF, Foote RL, Pollock BE Tags: J Neurosurg Source Type: research

Postoperative hemorrhage during the acute phase after direct or combined revascularization for moyamoya disease: risk factors, prognosis, and literature review.
CONCLUSIONS: Preoperative hypertension, CTP stage > III, and posterior circulation involvement are independent risk factors for postoperative ICH after direct or combined revascularization for MMD. After appropriate perioperative management, postoperative ICH has no significant correlations with the postoperative short-term and long-term neurofunctional status. PMID: 31628285 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 18, 2019 Category: Neurosurgery Authors: Chen Y, Ma L, Lu J, Chen X, Ye X, Zhang D, Zhang Y, Wang R, Zhao Y Tags: J Neurosurg Source Type: research

Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells.
CONCLUSIONS: Intravenous infusion of MSCs inhibited the inflammatory reaction to an implanted stent strut, and prevented progressive neointimal hyperplasia in the stented CCA and SCA in a porcine model. Thus, MSC treatment could attenuate the recurrence of cerebral ischemic events after stenting. PMID: 31585431 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 4, 2019 Category: Neurosurgery Authors: Nakazaki M, Oka S, Sasaki M, Kataoka-Sasaki Y, Onodera R, Komatsu K, Iihoshi S, Hiroura M, Kawaguchi A, Kocsis JD, Honmou O Tags: J Neurosurg Source Type: research

Racial phenotypes in moyamoya disease: a comparative analysis of clinical presentation and natural history in a single multiethnic cohort of 250 hemispheres.
CONCLUSIONS: This study suggests a comparatively more progressive course of MMD in Asians. Further studies are required to fully characterize the phenotypic distinctions between different races and underlying pathophysiological mechanisms. PMID: 31585430 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 4, 2019 Category: Neurosurgery Authors: Feghali J, Xu R, Yang W, Liew J, Tamargo RJ, Marsh EB, Huang J Tags: J Neurosurg Source Type: research

Moyamoya disease versus moyamoya syndrome: comparison of presentation and outcome in 338 hemispheres.
CONCLUSIONS: MMD and MMS have largely comparable clinical and angiographic phenotypes with analogously favorable responses to surgical revascularization. PMID: 31585423 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 4, 2019 Category: Neurosurgery Authors: Feghali J, Xu R, Yang W, Liew JA, Blakeley J, Ahn ES, Tamargo RJ, Huang J Tags: J Neurosurg Source Type: research

Revascularization and functional outcomes after mechanical thrombectomy: an update to key metrics.
CONCLUSIONS: As MT has established acute ischemic stroke as a neurosurgical disease, there is a pressing need to understand the hospital course, hospital- and procedure-related complications, and outcomes for this new patient population. The authors provide a detailed account of key metrics for MT with the latest device technology and identify the predictors of unfavorable outcomes and inpatient mortality. PMID: 31518981 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - September 13, 2019 Category: Neurosurgery Authors: Mouchtouris N, Al Saiegh F, Fitchett E, Andrews CE, Lang MJ, Ghosh R, Schmidt RF, Chalouhi N, Barros G, Zarzour H, Romo V, Herial N, Jabbour P, Tjoumakaris SI, Rosenwasser RH, Gooch MR Tags: J Neurosurg Source Type: research

Direct double bypass using the posterior auricular artery as initial surgery for moyamoya disease: technical note.
In this report, the authors describe double direct bypass performed using only the PAA as the donor in the initial surgery for MMD.In the authors' institution, MMD is routinely treated with an STA-MCA double bypass. Some patients, however, have poor STA development, and in these cases the PAA is used as the donor artery. The authors report the use of the PAA in the treatment of 4 MMD patients at their institution from 2013 to 2016. In all 4 cases, a double direct bypass was performed, with transposition of the PAA as the donor artery. Good patency was confirmed in all cases via intraoperative indocyanine green angiography ...
Source: Journal of Neurosurgery - August 23, 2019 Category: Neurosurgery Authors: Kurihara H, Yamaguchi K, Ishikawa T, Funatsu T, Matsuoka G, Omura Y, Okada Y, Kawamata T Tags: J Neurosurg Source Type: research

A perfusion territory shift attributable solely to the secondary collaterals in moyamoya patients: a potential risk factor for preoperative hemorrhagic stroke revealed by t-ASL and 3D-TOF-MRA.
CONCLUSIONS: t-ASL could reveal comprehensive MMD cerebral blood perfusion and the vivid perfusion territory shifts fed by the unilateral ICA and ECA and bilateral VAs in a noninvasive, straightforward, nonradioactive, and nonenhanced manner. 3D-TOF-MRA could subdivide t-ASL perfusion territory shifts according to their shunt arteries. A perfusion territory shift attributable to the secondary collaterals is a potential independent risk factor for preoperative hemorrhage in MMD patients. A perfusion territory shift fed by the primary collaterals may not have a strong effect on preoperative hemorrhage in MMD patients. These ...
Source: Journal of Neurosurgery - August 9, 2019 Category: Neurosurgery Authors: Gao XY, Li Q, Li JR, Zhou Q, Qu JX, Yao ZW Tags: J Neurosurg Source Type: research

Impact of temperature decline from the previous day as a trigger of spontaneous subarachnoid hemorrhage: case-crossover study of prefectural stroke database.
CONCLUSIONS: TDP, temperature decline from the highest of the previous day to the lowest of the day, was correlated with the incidence of spontaneous SAH, particularly in younger patients < 65 years old. PMID: 31277067 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - July 5, 2019 Category: Neurosurgery Authors: Fukuda H, Ninomiya H, Ueba Y, Ohta T, Kaneko T, Kadota T, Hamada F, Fukui N, Nonaka M, Watari Y, Nishimoto S, Fukuda M, Hayashi S, Izumidani T, Nishimura H, Moriki A, Lo B, Ueba T Tags: J Neurosurg Source Type: research

Letter to the Editor. Are disproportionate subarachnoid spaces and stroke history predictors of external lumbar drainage outcome in iNPH?
PMID: 31252390 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - June 28, 2019 Category: Neurosurgery Authors: Gallina P, Lastrucci G, Caini S, Porfirio B Tags: J Neurosurg Source Type: research

BIO alleviates inflammation through inhibition of GSK-3 β in a rat model of intracerebral hemorrhage.
CONCLUSIONS: BIO posttreatment inhibited microglia activation, prevented inflammation and hippocampal cell death, and ameliorated functional and morphological outcomes in a rat ICH model through inactivation of GSK-3β. PMID: 31226691 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - June 21, 2019 Category: Neurosurgery Authors: Zhao S, Liu Z, Yu Z, Wu X, Li R, Tang X Tags: J Neurosurg Source Type: research

Impact of basal ganglia damage after successful endovascular recanalization for acute ischemic stroke involving lenticulostriate arteries.
CONCLUSIONSThe basal ganglia are vulnerable and readily develop secondary infarction and hemorrhagic transformation despite successful recanalization. However, this does not have a significant impact on the clinical outcome of acute ischemic stroke with large vessel occlusion involving the lenticulostriate arteries. PMID: 31151109 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 31, 2019 Category: Neurosurgery Authors: Horie N, Morofuji Y, Iki Y, Sadakata E, Kanamoto T, Tateishi Y, Izumo T, Anda T, Morikawa M, Tsujino A, Matsuo T Tags: J Neurosurg Source Type: research

Strategy and effect of repeat bypass surgery for anterior/posterior circulation in refractory moyamoya disease.
CONCLUSIONSRepeat bypass surgery was feasible and effective to reduce further incidence of headache attack, transient ischemic attack, and ischemic/hemorrhagic stroke in moyamoya disease patients. Through precise radiological analysis, surgical procedures should be planned to yield maximal therapeutic effects. PMID: 31151103 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 31, 2019 Category: Neurosurgery Authors: Uchino H, Kashiwazaki D, Akioka N, Koh M, Kuwayama N, Houkin K, Kuroda S Tags: J Neurosurg Source Type: research

The impact of statin therapy after surgical or endovascular treatment of cerebral aneurysms.
CONCLUSIONSConsistent statin therapy was significantly associated with better prognosis after coil embolization or surgical clipping of cerebral aneurysms. PMID: 31125972 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 24, 2019 Category: Neurosurgery Authors: Song TJ, Oh SH, Kim J Tags: J Neurosurg Source Type: research

Arterial wall contrast enhancement in progressive moyamoya disease.
CONCLUSIONSA specific chronological increasing and decreasing pattern of arterial wall contrast enhancement associated with "beginning" as well as progression of angiopathy occurs in MMD patients. In clinical practice, CE-HR-MRI of the arterial wall may help to identify patients at risk of new strokes caused by disease progression and hence impel early treatment for future stroke prevention. Understanding of this temporary enhancement of the arterial wall might also bring new insights into the etiology of MMD. PMID: 31125967 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 24, 2019 Category: Neurosurgery Authors: Roder C, Hauser TK, Ernemann U, Tatagiba M, Khan N, Bender B Tags: J Neurosurg Source Type: research

Revascularization and functional outcomes after mechanical thrombectomy for acute ischemic stroke in elderly patients.
Abstract In BriefThe authors evaluated and compared outcomes of mechanical thrombectomy in elderly patients who were < 80, 80-89, or ≥ 90 years of age. In short, the study results demonstrated similar outcomes among all groups, indicating that age should not play a role in deciding which stroke patients may benefit from mechanical thrombectomy. PMID: 30925465 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 29, 2019 Category: Neurosurgery Authors: Andrews CE, Mouchtouris N, Fitchett EM, Al Saiegh F, Lang MJ, Romo VM, Herial N, Jabbour P, Tjoumakaris SI, Rosenwasser RH, Gooch MR Tags: J Neurosurg Source Type: research

Adverse events after clipping of unruptured intracranial aneurysms: the NSQIP unruptured aneurysm scale.
CONCLUSIONSThe NSQIP unruptured aneurysm scale may augment the risk stratification of patients undergoing microsurgical clipping of unruptured cerebral aneurysms. PMID: 30875693 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 15, 2019 Category: Neurosurgery Authors: Dasenbrock HH, Rudy RF, Smith TR, Gormley WB, Patel NJ, Frerichs KU, Aziz-Sultan MA, Du R Tags: J Neurosurg Source Type: research

Surgery for nerve injury: current and future perspectives.
Abstract In this review article, the authors offer their perspective on nerve surgery for nerve injury, with a focus on recent evolution of management and the current surgical management. The authors provide a brief historical perspective to lay the foundations of the modern understanding of clinical nerve injury and its evolving management, especially over the last century. The shift from evaluation of the nerve injury using macroscopic techniques of exploration and external neurolysis to microscopic interrogation, interfascicular dissection, and internal neurolysis along with the use of intraoperative electrophy...
Source: Journal of Neurosurgery - March 1, 2019 Category: Neurosurgery Authors: Midha R, Grochmal J Tags: J Neurosurg Source Type: research

Allogeneic adipose-derived mesenchymal stem cell sheet that produces neurological improvement with angiogenesis and neurogenesis in a rat stroke model.
CONCLUSIONSThe transplantation approach described here is expected to provide not only a paracrine effect but also a direct cell effect resulting in cell replacement that protects the damaged neurovascular unit. The behavioral improvement seen with this transplantation approach provides the basis for further research on cell sheet-based regenerative treatment as a translational treatment for patients with stroke. PMID: 30797215 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 22, 2019 Category: Neurosurgery Authors: Ryu B, Sekine H, Homma J, Kobayashi T, Kobayashi E, Kawamata T, Shimizu T Tags: J Neurosurg Source Type: research

dl-3-n-butylphthalide for alleviation of neurological deficit after combined extracranial-intracranial revascularization for moyamoya disease: a propensity score-matched analysis.
CONCLUSIONSPostoperative administration of NBP may alleviate perioperative neurological deficits after revascularization surgery for MMD, especially in patients with ischemic MMD and unfavorable preoperative status. The results of this study suggest that randomized controlled trials to assess the potential benefit of NBP in patients with MMD may be warranted. PMID: 30771781 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 15, 2019 Category: Neurosurgery Authors: Li Z, Lu J, Ma L, Wu C, Xu Z, Chen X, Ye X, Wang R, Zhao Y Tags: J Neurosurg Source Type: research

Characteristics and career outcomes of Neurosurgery Research and Education Foundation research fellowship recipients.
CONCLUSIONSThe majority of AANS/NREF research award recipients enter academics as fellowship-trained neurosurgeons, with approximately one-third obtaining NIH funding. Analysis of this unique cohort allows for identification of characteristics of academic success. PMID: 30738408 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 8, 2019 Category: Neurosurgery Authors: Wilson TA, Langston RG, Wong KH, Rodriguez A Tags: J Neurosurg Source Type: research

Effect of choroidal collateral vessels on de novo hemorrhage in moyamoya disease: analysis of nonhemorrhagic hemispheres in the Japan Adult Moyamoya Trial.
CONCLUSIONSThe present preliminary results suggest that the presence of choroidal collaterals affects the risk of de novo hemorrhage in the nonhemorrhagic hemisphere, subject to verification in larger studies. Further studies are needed to determine the optimal treatment strategy for nonhemorrhagic hemispheres and asymptomatic patients. PMID: 30738387 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 8, 2019 Category: Neurosurgery Authors: Funaki T, Takahashi JC, Houkin K, Kuroda S, Fujimura M, Tomata Y, Miyamoto S Tags: J Neurosurg Source Type: research

Revascularization surgery for symptomatic non-moyamoya intracranial arterial stenosis or occlusion.
CONCLUSIONSProphylactic arterial pedicle bypass surgery for anterior circulation ischemia is associated with high graft patency and low stroke and surgical complication rates. Higher risks are associated with acute procedures, typically for posterior circulation pathology and requiring VIGs. A carefully selected subgroup of individuals with hemodynamic insufficiency and ischemic symptoms is likely to benefit from cerebral revascularization surgery. PMID: 30738386 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 8, 2019 Category: Neurosurgery Authors: Gunawardena M, Rogers JM, Stoodley MA, Morgan MK Tags: J Neurosurg Source Type: research

Topographic correlation of infarct area on CT perfusion with functional outcome in acute ischemic stroke.
CONCLUSIONSThe results of this study provide evidence that several CTP parameters are independent predictors of functional outcome in patients with AIS and have potential to identify those patients most likely to benefit from reperfusion therapy in the treatment of AIS. PMID: 30641833 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 11, 2019 Category: Neurosurgery Authors: Haranhalli N, Mbabuike N, Grewal SS, Hasan TF, Heckman MG, Freeman WD, Gupta V, Vibhute P, Brown BL, Miller DA, Jahromi BS, Tawk RG Tags: J Neurosurg Source Type: research

Earlier tracheostomy and percutaneous endoscopic gastrostomy in patients with hemorrhagic stroke: associated factors and effects on hospitalization.
CONCLUSIONSThis study identified patient risk factors associated with increased likelihood of tracheostomy and PEG in patients with hemorrhagic stroke who were critically ill. Additionally, we found that the timing of tracheostomy was associated with length of ICU stay and overall hospital stay, and that the timing of PEG was associated with overall length of hospitalization. Complication rates related to tracheostomy and PEG in this population were minimal. This retrospective data set supports some benefit to earlier tracheostomy and PEG placement in this population and justifies the need for further prospective study. ...
Source: Journal of Neurosurgery - January 4, 2019 Category: Neurosurgery Authors: McCann MR, Hatton KW, Vsevolozhskaya OA, Fraser JF Tags: J Neurosurg Source Type: research

Two-year safety and clinical outcomes in chronic ischemic stroke patients after implantation of modified bone marrow-derived mesenchymal stem cells (SB623): a phase 1/2a study.
CONCLUSIONSIn this completed 2-year phase 1/2a study, implantation of SB623 cells in patients with stable chronic stroke was safe and was accompanied by improvements in clinical outcomes.Clinical trial registration no.: NCT01287936 (clinicaltrials.gov). PMID: 30497166 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 1, 2018 Category: Neurosurgery Tags: J Neurosurg Source Type: research

Letter to the Editor. Intracranial stenting in acute stroke.
PMID: 30239323 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - September 21, 2018 Category: Neurosurgery Authors: Gross BA, Jadhav AP, Jankowitz BT, Jovin TG Tags: J Neurosurg Source Type: research

Aspirin for primary prevention of stroke in traumatic cerebrovascular injury: association with increased risk of transfusion.
CONCLUSIONS Treatment with aspirin for the prevention of stroke in patients with initially asymptomatic TCVI carries a significantly increased risk of PRBC transfusion. Future studies are needed to determine if this risk is offset by a reduced risk of ischemic stroke. PMID: 29775142 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 18, 2018 Category: Neurosurgery Authors: Griffin RL, Falatko SR, Aslibekyan S, Strickland V, Harrigan MR Tags: J Neurosurg Source Type: research

Endovascular thrombectomy can be beneficial to acute ischemic stroke patients with large infarcts.
CONCLUSIONS Patients with AIS and ASPECTS < 6 definitely benefited from thrombectomy with higher sICH risk, whereas thrombolysis management showed similar efficacy to the control group. PMID: 29749914 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 11, 2018 Category: Neurosurgery Authors: Jiang S, Peng Y, Jing CH, Fei AH, Wang HR, Gao CJ, Chen M, Li Y, Pan S Tags: J Neurosurg Source Type: research

Mechanical thrombectomy in basilar artery occlusion: influence of reperfusion on clinical outcome and impact of the first-line strategy (ADAPT vs stent retriever).
CONCLUSIONS Among BAO patients, successful reperfusion is a strong predictor of a 90-day favorable outcome, and the choice of ADAPT as the first-line strategy achieves a significantly higher rate of complete reperfusion with a shorter procedure duration. PMID: 29327997 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 12, 2018 Category: Neurosurgery Authors: Gory B, Mazighi M, Blanc R, Labreuche J, Piotin M, Turjman F, Lapergue B, Endovascular Treatment in Ischemic Stroke (ETIS) Research Investigators Tags: J Neurosurg Source Type: research

Different learning curves between stent retrieval and a direct aspiration first-pass technique for acute ischemic stroke.
CONCLUSIONS In this initial experience, a higher recanalization rate and shorter procedure time were achieved with SR than with ADAPT. A high recanalization rate with SR was possible with relatively less clinical experience, whereas procedure time dramatically decreased with experience. These observed effects on the learning curve might be useful when choosing the method for initial endovascular treatment of acute ischemic stroke at relatively small stroke centers. PMID: 29303452 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 5, 2018 Category: Neurosurgery Authors: Nishi H, Ishii A, Nakahara I, Matsumoto S, Sadamasa N, Kai Y, Ishibashi R, Yamamoto M, Morita S, Nagata I Tags: J Neurosurg Source Type: research

Relationship between patient safety indicator events and comprehensive stroke center volume status in the treatment of unruptured cerebral aneurysms.
CONCLUSIONS In the treatment of unruptured cerebral aneurysms, PSI events occur relatively frequently and are associated with significant increases in morbidity and mortality. In patients treated at institutions achieving the volume thresholds for CSC certification, the likelihood of having a PSI event, and therefore the likelihood of poor outcome and mortality, was significantly decreased. These improvements are being driven by the improved outcomes in surgical patients, whereas outcomes and mortality in patients treated endovascularly were not sensitive to the CSC volume status of the hospital and showed no significant r...
Source: Journal of Neurosurgery - October 20, 2017 Category: Neurosurgery Authors: Washington CW, Taylor LI, Dambrino RJ, Clark PR, Zipfel GJ Tags: J Neurosurg Source Type: research

Predicting ischemic stroke after carotid artery stenting based on proximal calcification and the jellyfish sign.
CONCLUSIONS The jellyfish sign, proximal Ca, and LDL cholesterol were considered to be important predictors for new DWI lesions after CAS. These 3 factors can be easily determined during a standard clinical visit. Thus, these 3 variables-especially the jellyfish sign and proximal Ca-may be useful for reducing the ischemic stroke risk in patients with stenosis of the cervical carotid artery. PMID: 28686117 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - July 7, 2017 Category: Neurosurgery Authors: Ichinose N, Hama S, Tsuji T, Soh Z, Hayashi H, Kiura Y, Sakamoto S, Okazaki T, Ishii D, Shinagawa K, Kurisu K Tags: J Neurosurg Source Type: research

Severe carotid stenosis and delay of reperfusion in endovascular stroke treatment: an Interventional Management of Stroke-III study.
CONCLUSIONS Severe ipsilateral ICA stenosis was associated with a significantly longer time to reperfusion in the IMS-III trial. Although these findings may not translate directly to modern devices, this 28-minute delay in reperfusion has significant implications, raising concern over the treatment of tandem ICA stenosis and downstream large-vessel occlusion. PMID: 28156253 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 3, 2017 Category: Neurosurgery Authors: Gogela SL, Gozal YM, Zhang B, Tomsick TA, Ringer AJ, Broderick JP, Khatri P, Abruzzo TA Tags: J Neurosurg Source Type: research

Introducing a new era of ischemic stroke care.
PMID: 27203148 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 20, 2016 Category: Neurosurgery Authors: Mitha AP, Wong JH, Hill MD, Goyal M Tags: J Neurosurg Source Type: research

Comparison of non-stent retriever and stent retriever mechanical thrombectomy devices for the endovascular treatment of acute ischemic stroke.
CONCLUSIONS Stent retriever mechanical thrombectomy devices achieve higher recanalization rates than non-stent retriever devices in acute ischemic stroke with improved clinical and radiographic outcomes and safety. PMID: 27128585 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - April 29, 2016 Category: Neurosurgery Authors: Hentschel KA, Daou B, Chalouhi N, Starke RM, Clark S, Gandhe A, Jabbour P, Rosenwasser R, Tjoumakaris S Tags: J Neurosurg Source Type: research

Erratum: Stroke prevention by direct revascularization for patients with adult-onset moyamoya disease presenting with ischemia.
PMID: 26745479 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 8, 2016 Category: Neurosurgery Authors: Bang JS Tags: J Neurosurg Source Type: research

Stroke prevention by direct revascularization for patients with adult-onset moyamoya disease presenting with ischemia.
CONCLUSIONS Direct or combined revascularization for patients with adult-onset moyamoya disease presenting with ischemia can prevent further stroke. PMID: 26636391 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - December 4, 2015 Category: Neurosurgery Authors: Kim T, Oh CW, Kwon OK, Hwang G, Kim JE, Kang HS, Cho WS, Bang JS Tags: J Neurosurg Source Type: research

Decompressive hemicraniectomy: predictors of functional outcome in patients with ischemic stroke.
CONCLUSIONS History of stroke, diabetes, myocardial infarction, peak MLS > 10 mm, increasing duration from onset of stroke to DH, and presence of pupillary dilation prior to intervention are associated with a worse functional outcome. PMID: 26613165 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 27, 2015 Category: Neurosurgery Authors: Daou B, Kent AP, Montano M, Chalouhi N, Starke RM, Tjoumakaris S, Rosenwasser RH, Jabbour P Tags: J Neurosurg Source Type: research

Association of apolipoprotein E gene polymorphism with small-vessel lesions and stroke type in moyamoya disease: a preliminary study.
CONCLUSIONS These preliminary results did not show a difference in APOE gene polymorphisms between patients with MMD and healthy persons. However, they imply that APOE gene polymorphisms may play certain roles in the presence of microbleeds but not microinfarcts in patients with MMD. A further confirmatory study is necessary to elucidate the effect of APOE gene polymorphisms and SVLs on the future incidence of stroke in patients with MMD. PMID: 26566210 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 13, 2015 Category: Neurosurgery Authors: Jang DK, Huh PW, Lee KS Tags: J Neurosurg Source Type: research

Intraarterial administration of norcantharidin attenuates ischemic stroke damage in rodents when given at the time of reperfusion: novel uses of endovascular capabilities.
CONCLUSIONS Intraarterial NCTD significantly improved outcome when administered at the time of reperfusion in a spontaneously hypertensive rat stroke model. This study suggests that supplementing endovascular revascularization with local neuroprotective drug therapy may be a viable therapeutic strategy. PMID: 26544777 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 6, 2015 Category: Neurosurgery Authors: Khan IS, Odom M, Ehtesham M, Colvin D, Quarles CC, McLaughlin B, Singer RJ Tags: J Neurosurg Source Type: research

Impact of transfer status on hospitalization cost and discharge disposition for acute ischemic stroke across the US.
CONCLUSIONS The study showed that hospital cost for acute stroke intervention is significantly higher for a transferred patient than for a direct admission. Moreover, the frequency of OTR discharge was significantly higher among transferred patients than direct admissions. Future strategies should focus on ways and means of transporting patients appropriately and directly to stroke centers. PMID: 26452123 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 9, 2015 Category: Neurosurgery Authors: Sonig A, Lin N, Krishna C, Natarajan SK, Mokin M, Hopkins LN, Snyder KV, Levy EI, Siddiqui AH Tags: J Neurosurg Source Type: research

Aneurysm location and clipping versus coiling for development of secondary normal-pressure hydrocephalus after aneurysmal subarachnoid hemorrhage: Japanese Stroke DataBank.
CONCLUSIONS Patients with low-grade SAH caused by a ruptured MCA aneurysm had a low risk for the development of sNPH. In contrast, patients with high-grade SAH caused by a ruptured ACA aneurysm had a higher risk for sNPH. Endovascular coiling might confer a lower risk of developing sNPH than microsurgical clipping. PMID: 26230474 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - July 31, 2015 Category: Neurosurgery Authors: Yamada S, Ishikawa M, Yamamoto K, Ino T, Kimura T, Kobayashi S, Japan Standard Stroke Registry Study Group Tags: J Neurosurg Source Type: research

Editorial: Health insurance status and stroke.
PMID: 25658790 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 6, 2015 Category: Neurosurgery Authors: Connolly ES Tags: J Neurosurg Source Type: research

Health disparities and stroke: the influence of insurance status on the prevalence of patient safety indicators and hospital-acquired conditions.
CONCLUSIONS Insurance status is an independent predictor of patient safety events after stroke. Private insurance is associated with lower mortality, shorter lengths of stay, and improved clinical outcomes. PMID: 25658779 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 6, 2015 Category: Neurosurgery Authors: Fargen KM, Neal D, Blackburn SL, Hoh BL, Rahman M Tags: J Neurosurg Source Type: research

The influence of decompressive craniectomy for major stroke on early cerebral perfusion.
CONCLUSIONS The presurgical perfusion abnormalities likely reflected local pressure-induced hypoperfusion with impaired autoregulation. The improvement in perfusion after decompression implied an increase in perfusion pressure, likely linked to partial restoration of autoregulation. The increase in perfusion that was observed might partially be responsible for improved clinical outcome following decompressive surgery for major stroke. The predictive value of perfusion CT on outcome needs to be evaluated in larger trials. PMID: 25635482 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 30, 2015 Category: Neurosurgery Authors: Slotty PJ, Kamp MA, Beez T, Beenen H, Steiger HJ, Turowski B, Hänggi D Tags: J Neurosurg Source Type: research

64-detector CT angiography within 24 hours after carotid endarterectomy and correlation with postoperative stroke.
CONCLUSIONS CTA within 24 hours of CEA demonstrates characteristic anatomical findings. CCA step-offs and ECA flaps are relatively common and clinically insignificant, whereas ICA/CCA flaps and thrombi are less frequently seen and are associated with postoperative stroke/TIA. PMID: 25555168 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 2, 2015 Category: Neurosurgery Authors: Gallati CP, Jain M, Damania D, Kanthala AR, Jain AR, Koch GE, Kung NT, Wang HZ, Replogle RE, Jahromi BS Tags: J Neurosurg Source Type: research

Vessel perforation during withdrawal of Trevo ProVue stent retriever during mechanical thrombectomy for acute ischemic stroke.
Abstract The authors report a case of an intracranial extravasation during the withdrawal of a Trevo ProVue stent retriever device in a patient being treated for acute ischemic stroke. An 82-year-old woman developed sudden left hemiparesis and aphasia during an urgent cardiac catheterization procedure for a non-ST elevation myocardial infarction. She had a baseline National Institutes of Health Stroke Scale (NIHSS) score of at least 10 and no improvement with intravenous administration of tissue plasminogen activator (tPA). Cerebral angiography was performed with conscious sedation, confirming an occlusion of the ...
Source: Journal of Neurosurgery - June 13, 2014 Category: Neurosurgery Authors: Leishangthem L, Satti SR Tags: J Neurosurg Source Type: research