Filtered By:
Source: Stroke
This page shows you your search results in order of date. This is page number 17.
Order by Relevance | Date
Total 4002 results found since Jan 2013.
Characteristics of Randomized Trials Focusing on Stroke due to Intracerebral Hemorrhage Clinical Sciences
Background and Purpose—The absence of treatments for intracerebral hemorrhage with significant consistent benefit in randomized controlled trials (RCTs) could be because of lack of treatment efficacy or the design of RCTs.Methods—We searched the Cochrane Stroke Group Trials Register in December 2015 for completed and published RCTs reporting clinical outcome in adults with intracerebral hemorrhage. We collected data on publication year and language, study characteristics, and effect size. We regarded RCTs to be at lower risk of bias if they performed ≥2 of describing randomization, using blinding, or specifying the p...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Arina Tamborska, Michael T.C. Poon, Rustam Al-Shahi Salman Tags: Meta Analysis, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research
External Validation of Risk Scores for Major Bleeding in a Population-Based Cohort of Transient Ischemic Attack and Ischemic Stroke Patients Clinical Sciences
Conclusions—The S2TOP-BLEED score shows modest performance in a population-based cohort of patients with a transient ischemic attack or ischemic stroke. Although bleeding risks were associated with risks of ischemic events, risk stratification may still be useful to identify a subgroup of patients at particularly high risk of bleeding, in whom preventive measures are indicated.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Nina A. Hilkens, Linxin Li, Peter M. Rothwell, Ale Algra, Jacoba P. Greving Tags: Risk Factors, Secondary Prevention, Ischemic Stroke Original Contributions Source Type: research
Long-Term Survival After Intravenous Thrombolysis for Ischemic Stroke Clinical Sciences
Background and Purpose—Intravenous thrombolysis with alteplase is one of the few approved treatments for acute ischemic stroke; nevertheless, little is known about its long-term effects on survival and recovery because clinical trials follow-up times are limited.Methods—Patients registered between January 2005 and December 2015, to the population-based South London Stroke Register of first-ever strokes. Propensity score was used to match thrombolyzed and control cases to a 1:2 ratio by demographical and clinical covariates. The primary outcome was survival up to 10 years using Kaplan–Meier estimates, Cox proportional...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Walter Muruet, Anthony Rudd, Charles D.A. Wolfe, Abdel Douiri Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Association of Progression of Carotid Artery Wall Volume and Recurrent Transient Ischemic Attack or Stroke Clinical Sciences
Conclusions—The annual progression of carotid wall volume is independently associated with recurrent ischemic cerebrovascular events, and this measurement has added value for intraplaque hemorrhage and fibrous cap rupture in predicting future events.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mingming Lu, Peng Peng, Yuanyuan Cui, Huiyu Qiao, Dongye Li, Jianming Cai, Xihai Zhao Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Atherosclerosis Original Contributions Source Type: research
Staging Hemodynamic Failure With Blood Oxygen-Level-Dependent Functional Magnetic Resonance Imaging Cerebrovascular Reactivity Clinical Sciences
We examined the agreement between the 2 imaging modalities and hypothesized that quantitative CVR can be a surrogate imaging marker to assess hemodynamic failure.Methods—Nineteen data sets of subjects with chronic cerebrovascular steno-occlusive disease (age, 60±11 years; 4 women) and unilaterally impaired perfusion reserve on Diamox-challenged (15O-)H2O PET were studied and compared with a standardized BOLD functional magnetic resonance imaging+CO2 examination within 6 weeks (8±19 days). Agreement between quantitative CBF- and CVR-based perfusion reserve was assessed. Hemodynamic failure was staged according to PET fi...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Jorn Fierstra, Christiaan van Niftrik, Geoffrey Warnock, Susanne Wegener, Marco Piccirelli, Athina Pangalu, Giuseppe Esposito, Antonios Valavanis, Alfred Buck, Andreas Luft, Oliver Bozinov, Luca Regli Tags: Functional Magnetic Resonance Imaging (fMRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Oxidative Stress Biomarkers of Brain Damage Clinical Sciences
Conclusions—Elevated hyperacute plasma F2-isoP concentrations independently predict the occurrence of IG and IG volume in patients with acute ischemic stroke. If validated in future studies, measuring plasma F2-isoP might be helpful in the acute setting to stratify patients with acute ischemic stroke for relative severity of ischemic injury and expected progression.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Svetlana Lorenzano, Natalia S. Rost, Muhib Khan, Hua Li, Fabricio O. Lima, Matthew B. Maas, Rebecca E. Green, Tijy K. Thankachan, Allison J. Dipietro, Ken Arai, Angel T. Som, Loc-Duyen D. Pham, Ona Wu, Gordon J. Harris, Eng H. Lo, Jeffrey B. Blumberg, Pau Tags: Ischemic Stroke Original Contributions Source Type: research
Predictors of Thrombolysis Administration in Mild Stroke Clinical Sciences
Conclusions—Mild acutely presenting stroke patients are more likely to receive thrombolysis if they are young, white, or Hispanic and arrive early to the hospital with more severe neurological presentation. Identification of predictors of thrombolysis is important in design of future studies to assess the use of thrombolysis for mild stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Negar Asdaghi, Kefeng Wang, Maria A. Ciliberti-Vargas, Carolina Marinovic Gutierrez, Sebastian Koch, Hannah Gardener, Chuanhui Dong, David Z. Rose, Enid J. Garcia, W. Scott Burgin, Juan Carlos Zevallos, Tatjana Rundek, Ralph L. Sacco, Jose G. Romano Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Effects of Prehospital Thrombolysis in Stroke Patients With Prestroke Dependency Clinical Sciences
Background and Purpose—Data on effects of intravenous thrombolysis on outcome of patients with ischemic stroke who are dependent on assistance in activities of daily living prestroke are scarce. Recent registry based analyses in activities of daily –independent patients suggest that earlier start of intravenous thrombolysis in the prehospital setting leads to better outcomes when compared with the treatment start in hospital. We evaluated whether these observations can be corroborated in patients with prestroke dependency.Methods—This observational, retrospective analysis included all patients with acute ischemic str...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Christian H. Nolte, Martin Ebinger, Jan F. Scheitz, Alexander Kunz, Hebun Erdur, Frederik Geisler, Tim-Bastian Braemswig, Michal Rozanski, Joachim E. Weber, Matthias Wendt, Katja Zieschang, Jochen B. Fiebach, Kersten Villringer, Ulrike Grittner, Sabina Ka Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Erythrocyte Fraction Within Retrieved Thrombi Contributes to Thrombolytic Response in Acute Ischemic Stroke Clinical Sciences
Conclusions—In EVT-attempted patients with acute ischemic stroke, IVT responsiveness would be closely associated with RBC fraction.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mun Hee Choi, Geun Hwa Park, Jin Soo Lee, Sung Eun Lee, Seong-Joon Lee, Jang-Hee Kim, Ji Man Hong Tags: Ischemic Stroke Original Contributions Source Type: research
First Pass Effect Clinical Sciences
Conclusions—The achievement of complete revascularization from a single Solitaire thrombectomy device pass (FPE) is associated with significantly higher rates of good clinical outcome. The FPE is more frequently associated with the use of balloon guide catheters and less likely to be achieved with internal carotid artery terminus occlusion.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Osama O. Zaidat, Alicia C. Castonguay, Italo Linfante, Rishi Gupta, Coleman O. Martin, William E. Holloway, Nils Mueller-Kronast, Joey D. English, Guilherme Dabus, Tim W. Malisch, Franklin A. Marden, Hormozd Bozorgchami, Andrew Xavier, Ansaar T. Rai, Mich Tags: Ischemic Stroke Original Contributions Source Type: research
Second-Generation Hydrogel Coils for the Endovascular Treatment of Intracranial Aneurysms Clinical Sciences
Conclusions—Our results suggest that endovascular coil embolization with second-generation hydrogel coils may reduce the rate of unfavorable outcome events in patients with small- and medium-sized intracranial aneurysms.Clinical Trial Registration—URL: https://www.drks.de/drks_web/. Unique identifier: DRKS00003132.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Christian A. Taschner, Rene Chapot, Vincent Costalat, Paolo Machi, Patrick Courtheoux, Xavier Barreau, Jerome Berge, Laurent Pierot, Krzysztof Kadziolka, Betty Jean, Raphael Blanc, Alessandra Biondi, Herve Brunel, Sophie Gallas, Ansgar Berlis, Denis Herbr Tags: Cerebral Aneurysm, Cerebrovascular Procedures Original Contributions Source Type: research
Hyperintense Vessels, Collateralization, and Functional Outcome in Patients With Stroke Receiving Endovascular Treatment Clinical Sciences
Conclusions—Low FHV-ASPECTS is associated with both better collateral status and better 3-month functional outcome in acute stroke patients with M1 vessel occlusion.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Alexander H. Nave, Anna Kufner, Philipp Bucke, Eberhard Siebert, Stefan Kliesch, Ulrike Grittner, Hansȷorg Bazner, Thomas Liebig, Matthias Endres, Jochen B. Fiebach, Christian H. Nolte, Martin Ebinger, Hans Henkes Tags: Angiography, Magnetic Resonance Imaging (MRI), Prognosis, Revascularization, Ischemic Stroke Original Contributions Source Type: research
Clinical and Demographic Characteristics Associated With Suboptimal Primary Stroke and Transient Ischemic Attack Prevention Clinical Sciences
Conclusions—Knowing the patient characteristics predictive of missed opportunities for stroke prevention may help primary care identify and appropriately manage these patients. Improving the management of these groups may reduce their risk and potentially prevent large number of future strokes and TIAs in the population.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Grace M. Turner, Melanie Calvert, Max G. Feltham, Ronan Ryan, Samuel Finnikin, Tom Marshall Tags: Epidemiology, Primary Prevention, Hypertension, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research
Validating the TeleStroke Mimic Score Clinical Sciences
We report the area under the curve in receiver-operating characteristic curve analysis with 95% confidence interval for our previously derived TM score in which lower TM scores correspond with a higher likelihood of being a stroke mimic.Results—Based on final diagnosis at the end of the telestroke consultation, there were 630 of 1930 (32.6%) stroke mimics in the external validation cohort. All 6 variables included in the score were significantly different between patients with ischemic cerebrovascular disease versus stroke mimics. The TM score performed well (area under curve, 0.72; 95% confidence interval, 0.70–0.73; P
Source: Stroke - February 26, 2018 Category: Neurology Authors: Syed F. Ali, Gordian J. Hubert, Jeffrey A. Switzer, Jennifer J. Majersik, Roland Backhaus, L. Wylie Shepard, Kishore Vedala, Lee H. Schwamm Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease Clinical Sciences
Conclusions—Although a feature of small-vessel disease, PvS are not a predictor of cognitive decline, in contrast to lacunes. This study highlights the importance of carefully differentiating between lacunes and PvS in studies investigating vascular cognitive impairment.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Philip Benjamin, Sarah Trippier, Andrew J. Lawrence, Christian Lambert, Eva Zeestraten, Owen A. Williams, Bhavini Patel, Robin G. Morris, Thomas R. Barrick, Andrew D. MacKinnon, Hugh S. Markus Tags: Aging, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
