Query: stroke

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Source: The American Journal of Emergency Medicine

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Total 184 results found since Jan 2013.

Impact of CT scanner location on door to imaging time for emergency department stroke evaluation
Stroke is a potentially serious condition commonly diagnosed in the ED. Time to diagnosis can be crucial to maximizing outcome in a majority of ischemic stroke cases amenable to thrombolytic therapy.
Source: The American Journal of Emergency Medicine - August 14, 2019 Category: Emergency Medicine Authors: William Bonadio Source Type: research

Implementation of a pilot electronic stroke outcome reporting system for emergency care providers
Emergency department (ED) providers and clinicians find that feedback on acute stroke patients is rewarding, valuable to professional development, and helpful for practice improvement. However, feedback is rarely provided, particularly for patients with stroke. Here we describe the implementation of an electronic stroke outcome reporting tool for providing feedback to ED providers.
Source: The American Journal of Emergency Medicine - July 11, 2019 Category: Emergency Medicine Authors: William L. Scheving, Joseph M. Ebersole, Michael Froehler, Donald Moore, Kiersten Brown-Espaillat, James Closser, Wesley H. Self, Michael J. Ward Source Type: research

Neighborhood-level stroke hot spots within major United States cities
Identifying communities at high risk of stroke is an important step in improving systems of stroke care. Stroke is known to show spatial clustering at the state and county levels, but it is not known if clusters are present within city boundaries.
Source: The American Journal of Emergency Medicine - June 25, 2019 Category: Emergency Medicine Authors: Daniel A. Dworkis, James Marvel, Nerses Sanossian, Sanjay Arora Source Type: research

Thrombolysis for atlantoaxial dislocation mimicking acute ischemic stroke: Case report and review
The frequency of stroke mimics among stroke patients has been reported to be up to 30%, and that in patients who receive thrombolytic therapy ranges between 1% and 16%. Atlantoaxial dislocation with myelopathy mimicking stroke is extremely rare. An 83-year-old man with a history of old cerebellar infarction presented to the emergency department with acute left hemiplegia after a chiropractic manipulation of the neck and back several hours before symptom onset. Mild hypoesthesia was observed on his left limbs.
Source: The American Journal of Emergency Medicine - March 27, 2019 Category: Emergency Medicine Authors: Adam Tsou, Yu-Hsiu Juan, Tsu-Yi Chen, Shinn-Kuang Lin Source Type: research

A new marker identification of high risk stroke patients: Jugular saturation
The aim of this prospective study; to investigate in emergency patients with stroke the relationship between jugular saturation and National Institutes of Health Stroke Scale (NIHSS), lesion volume and mortality score.
Source: The American Journal of Emergency Medicine - March 27, 2019 Category: Emergency Medicine Authors: Mevlut Guven, Nazire Belgin Akilli, Ramazan Koylu, Vefa Oner, Merve Guven, Muhammed Rasit Ozer Source Type: research

Thrombolysis for atlantoaxial dislocation mimicking acute ischemic stroke
The frequency of stroke mimics among stroke patients has been reported to be up to 30%, and that in patients who receive thrombolytic therapy ranges between 1% and 16%. Atlantoaxial dislocation with myelopathy mimicking stroke is extremely rare. An 83-year-old man with a history of old cerebellar infarction presented to the emergency department with acute left hemiplegia after a chiropractic manipulation of the neck and back several hours before symptom onset. Mild hypoesthesia was observed on his left limbs.
Source: The American Journal of Emergency Medicine - March 27, 2019 Category: Emergency Medicine Authors: Adam Tsou, Yu-Hsiu Juan, Tsu-Yi Chen, Shinn-Kuang Lin Tags: Case Report Source Type: research

Clinical usefulness of brain-derived neurotrophic factor and visinin-like protein-1 in early diagnostic tests for acute stroke
Lack of a rapid biochemical test for acute stroke is a limitation in the diagnosis and management of acute stroke. The aim of this study is to evaluate the efficacy of BDNF and VILIP-1 as diagnostic markers in acute ischemic stroke and as predictors of mortality.
Source: The American Journal of Emergency Medicine - February 25, 2019 Category: Emergency Medicine Authors: Abdullah Algin, M. Ozgur Erdogan, Irfan Aydin, M. Kaan Poyraz, Mehmet Sirik Source Type: research

How should we treat patients who wake up with a stroke? A review of recent advances in management of acute ischemic stroke
Acute ischemic strokes account for 85% of all strokes and are the fifth leading cause of mortality in the United States. About one in five of all ischemic strokes occur during sleep and are not noticed until the patient wakes up with neurological deficits. There is growing evidence to support that a significantly higher number of stroke patients could benefit from more aggressive care, especially those patients who wake up with strokes. There is increasing research to support a physiologically-based approach based on advanced imaging rather than simply a time-based determination of whether or not a patient would benefit from reperfusion.
Source: The American Journal of Emergency Medicine - February 21, 2019 Category: Emergency Medicine Authors: Danielle Biggs, Michael E. Silverman, Frank Chen, Brian Walsh, Peter Wynne Source Type: research

Financial relationships with industry among guideline authors for the management of acute ischemic stroke
To characterize the prevalence of industry relationships among authors of acute ischemic stroke (AIS) guidelines and its association with graded evidence.
Source: The American Journal of Emergency Medicine - January 24, 2019 Category: Emergency Medicine Authors: Joshua D. Niforatos, Richard M. Pescatore Source Type: research

Optimal treatment modality for coexisting acute myocardial infarction and ischemic stroke
We present a rare case of coexisting thrombosis of the coronary artery and mid cerebral artery that was managed successfully with tissue plasminogen activator thrombolytic therapy.
Source: The American Journal of Emergency Medicine - December 31, 2018 Category: Emergency Medicine Authors: Fatih Gungoren, Feyzullah Besli, Zulkif Tanriverdi, Ozcan Kocaturk Source Type: research

Seizure in code stroke: Stroke mimic and initial manifestation of stroke
The objective of this study was to analyze the frequency, characteristics and results of neuroimaging including CT perfusion in patients with seizures manifesting initially as stroke-like symptoms.
Source: The American Journal of Emergency Medicine - December 27, 2018 Category: Emergency Medicine Authors: Soo Jeong Kim, Dong Wook Kim, Hahn Young Kim, Hong Gee Roh, Jeong-Jin Park Source Type: research

Tenecteplase utility in acute ischemic stroke patients: A clinical review of current evidence
Acute ischemic stroke is leading cause of disability in the United States. Treatment is aimed at reducing impact of cerebral clot burden and life-long disability. Traditional fibrinolytic treatment with recombinant tissue plasminogen activator (tPA) has shown to be effective but at high risk of major bleeding. Multiple studies have evaluated tenecteplase as an alternative to tPA.
Source: The American Journal of Emergency Medicine - November 14, 2018 Category: Emergency Medicine Authors: Amelia Nelson, Gregory Kelly, Richard Byyny, Catherine Dionne, Candice Preslaski, Kevin Kaucher Source Type: research

Acute ischemic stroke in a trauma cohort: Incidence and diagnostic challenges
We report its incidence in trauma patients following their presentation at our institution.
Source: The American Journal of Emergency Medicine - November 3, 2018 Category: Emergency Medicine Authors: Kevin Yeboah, Aakash Bodhit, Ali Al Balushi, Erik Krause, Abhay Kumar Source Type: research

Pharmacoeconomic impact of an alternative workflow process for stroke
The objective of this study was to evaluate a new multidisciplinary process in which intravenous alteplase (tPA) waste, used for acute ischemic stroke (AIS), was salvaged in an attempt to maximize cost effectiveness without impacting door-to-needle (DTN) administration times.
Source: The American Journal of Emergency Medicine - October 16, 2018 Category: Emergency Medicine Authors: Brian W. Gilbert, Joel B. Huffman, Joe Slechta, Christine Porter, John M. Gallagher Source Type: research

National trends in stroke and TIA care in U.S. emergency departments and inpatient hospitalizations (2006 –2014)
We examine recent trends in U.S. emergency department (ED) and hospital care for stroke and transient ischemic attack (TIA).
Source: The American Journal of Emergency Medicine - August 8, 2018 Category: Emergency Medicine Authors: Islam I. Bedaiwi, Sukayna Z. Alfaraj, Jesse M. Pines Source Type: research

Acute stroke presenting with isolated acalculia
We report the case of a 63-year-old male with a 1  day history of isolated acalculia that was found to have a left parietal lobe infarct with several smaller infarcts in the left occipital lobe.
Source: The American Journal of Emergency Medicine - June 16, 2018 Category: Emergency Medicine Authors: Michael Grimaldi, Rebecca Jeanmonod Source Type: research

Contribution of routine cardiac biological markers to the etiological workup of ischemic stroke
Optimization of the detection of atrial fibrillation following stroke is mandatory. Unfortunately, access to long-term cardiac monitoring is limited in many centers. The aim of this study was to assess the potential usefulness of three routine biological markers, troponin, D-dimers and BNP, measured in acute stroke phase in the selection of patients at risk of cardio-embolic stroke.
Source: The American Journal of Emergency Medicine - May 17, 2018 Category: Emergency Medicine Authors: C. Tomich, J.S. Liegey, S. Sagnier, S. Olindo, M. Poli, S. Debruxelles, F. Rouanet, P. Renou, I. Sibon Source Type: research

Challenge of intravascular volume assessment in acute ischemic stroke
Retrospective data indicates that dehydration in acute ischemic stroke patients may be common, even though these patients frequently have elevated blood pressure. We sought to evaluate clinical and laboratory measures of intravascular volume status compared to more objective measures using ultrasound measurements of the inferior vena cava (IVC).
Source: The American Journal of Emergency Medicine - February 2, 2018 Category: Emergency Medicine Authors: Joseph B. Miller, Alexander Lee, Julian P. Suszanski, Madison Tustian, Jessica Levely Corcoran, Steven Moore, Lauren Rodriguez, Christopher A. Lewandowski Source Type: research

Hemodynamic characteristics of suspected stroke in the emergency department
The objective of this study was to identify baseline hemodynamic characteristics of emergency department (ED) patients with suspected acute stroke.
Source: The American Journal of Emergency Medicine - August 7, 2017 Category: Emergency Medicine Authors: Joseph B. Miller, Richard M. Nowak, Brian P. Reed, Salvatore DiSomma, Prabath Nanayakkara, Michele Moyer, Scott Millis, Harish Kinni, Phillip Levy Source Type: research

The impact of IV alteplase on long-term patient survival: The Georgia Coverdell acute stroke registry's experience
This study assessed the impact of thrombolytic treatment by alteplase on 1-year mortality and readmission among acute ischemic stroke patients.
Source: The American Journal of Emergency Medicine - July 31, 2017 Category: Emergency Medicine Authors: Moges S. Ido, Michael R. Frankel, Ike S. Okosun, Richard B. Rothenberg Tags: Original Contribution Source Type: research

The impact of intravenous alteplase on long-term patient survival: The Georgia Coverdell acute stroke registry's experience
This study assessed the impact of thrombolytic treatment by alteplase on 1-year mortality and readmission among acute ischemic stroke patients.
Source: The American Journal of Emergency Medicine - July 31, 2017 Category: Emergency Medicine Authors: Moges S. Ido, Michael R. Frankel, Ike S. Okosun, Richard B. Rothenberg Source Type: research

Chemotherapy induced stroke mimic: 5-Fluorouracil encephalopathy fulfilling criteria for tissue plasminogen activator therapy
Stroke mimics, especially those involving chemotherapy related neurotoxicity, can confound the clinical diagnosis of acute stroke. Here we describe the case of a 63year-old male with a recent history of stage IIIC colon cancer who presented with confusion on the second day of modified FOLFOX6 (5-fluorouracil/oxaliplatin) chemotherapy and subsequently received alteplase, tissue plasminogen activator therapy (tPA), for presumed ischemic stroke. Magnetic resonance imaging scans after tPA administration did not reveal evidence of an infarction and the patients' neurological symptoms resolved completely after discontinuation of...
Source: The American Journal of Emergency Medicine - July 6, 2017 Category: Emergency Medicine Authors: May Thuy Nguyen, Robyn Stoianovici, Luigi Brunetti Source Type: research

Cerebellar stroke presenting with isolated dizziness: Brain MRI in 136 patients
To evaluate occurrence of cerebellar stroke in Emergency Department (ED) presentations of isolated dizziness (dizziness with a normal exam and negative neurological review of systems).
Source: The American Journal of Emergency Medicine - June 21, 2017 Category: Emergency Medicine Authors: Michael D. Perloff, Nimesh S. Patel, Carlos S. Kase, Anuja U. Oza, Barbara Voetsch, Jose R. Romero Source Type: research

Can we imagine a survival chain also for ischemic stroke?
I read with great interest the article about the University of Amiens experience in the management of acute stroke [1] and the concept of “door-to-needle” time, so similar to the best known “door-to-balloon” one. During my recent training period in an excellent Stroke Unit, I've directly experienced a quite brand new concept, brought by mechanical thrombectomy, the “door-to-reperfusion” time. We know from meta-analysis dat a that for every 9-minute delay in reperfusion, 1 of every 100 treated patients had a worse disability outcome (+1 point on MrS scale) [2].
Source: The American Journal of Emergency Medicine - May 29, 2017 Category: Emergency Medicine Authors: Aurora Vecchiato Source Type: research

An educational intervention allows for greater prehospital recognition of acute stroke
We performed a study to determine whether a brief educational intervention directed at pre-hospital providers would increase the identification of stroke victims in the pre-hospital setting. The purpose of this IRB approved, before-and-after research project was to determine whether the implementation of Advanced Stroke Life Support Class (ASLS) [1] training for pre-hospital providers would lead to improved field identification of stroke.
Source: The American Journal of Emergency Medicine - May 23, 2017 Category: Emergency Medicine Authors: Tara K. Henry-Morrow, Bryan D. Nelson, Erin Conahan, Claranne Mathiesen, Bernadette Glenn-Porter, Matthew T. Niehaus, Lauren M. Porter, Mitchell R. Gesell, Gregory T. Monaghan, Jeanne L. Jacoby Tags: Correspondence Source Type: research

Usefulness of glycated hemoglobin A1c-based adjusted glycemic variables in diabetic patients presenting with acute ischemic stroke
The objective of the current study was to assess whether HbA1c-based adjusted glycemic variables were associated with unfavorable outcomes among patients admitted to the hospital for AIS.
Source: The American Journal of Emergency Medicine - March 21, 2017 Category: Emergency Medicine Authors: Chih-Jen Yang, Wen-I Liao, Jen-Chun Wang, Chia-Lin Tsai, Jiunn-Tay Lee, Giia-Sheun Peng, Chien-Hsing Lee, Chin-Wang Hsu, Shih-Hung Tsai Source Type: research

Regional disparities in the quality of stroke care
This study characterized geographic disparities in stroke care quality to assess whether improved access to neurological services has the potential to bridge the care quality gap, particularly in terms of alteplase (rt-PA) administration.
Source: The American Journal of Emergency Medicine - March 19, 2017 Category: Emergency Medicine Authors: Seth Seabury, Katalin Bognar, Yaping Xu, Caroline Huber, S. Renee Commerford, Darren Tayama Source Type: research

Effect of paracetamol (acetaminophen) on body temperature in acute stroke: A meta-analysis
The objective of this study was to assess the efficacy of paracetamol (acetaminophen) on body temperature in acute stroke.
Source: The American Journal of Emergency Medicine - March 18, 2017 Category: Emergency Medicine Authors: Junjie Fan, Chensong Cheng, Hongsen Cheng, Ren Wang, Linhao Ma Source Type: research

Creation of an intensive care unit and organizational changes in an adult emergency department: impact on acute stroke management
Following the reorganization of a University Medical Center onto a single campus, an Intensive Care Unit was created within the adult Emergency Department (ED ICU). We assessed the effects of these organizational changes on acute stroke management and the intravenous administration of recombinant tissue plasminogen activator (IV rtPA), as characterized by the thrombolysis rate, door-to-needle time (DNT) and outcome at 3 months.
Source: The American Journal of Emergency Medicine - January 9, 2017 Category: Emergency Medicine Authors: Laurent Puy, Chantal Lamy, Sandrine Canaple, Audrey Arnoux, Nicolas Laine, Ella Iacob, Jean-Marc Constans, Olivier Godefroy Source Type: research

Thrombolytic therapy-associated acute myocardial infarction in patients with acute ischemic stroke: A treatment dilemma
Acute myocardial infarction (AMI) is uncommon in the acute phase of acute ischemic stroke (AIS) and occurs in approximately 1% of the population. Here, we report a paradoxical case of AMI during tissue plasminogen activator (t-PA) infusion for AIS. We review and analyze the previously reported cases. We found that only patients with AMI which occurred after thrombolytic therapy for AIS who received an adequate combination of anticoagulation plus percutaneous coronary intervention survived their events.
Source: The American Journal of Emergency Medicine - November 22, 2016 Category: Emergency Medicine Authors: Chih-Jen Yang, Po-Chuan Chen, Chin-Sheng Lin, Chia-Lin Tsai, Shih-Hung Tsai Source Type: research

Neutrophil to lymphocyte ratio and the hematoma volume and stroke severity in acute intracerebral hemorrhage patients
Neutrophil to lymphocyte ratio (NLR) serves as a powerful inflammatory marker for predicting cardiovascular events. Here, we investigate whether admission NLR is associated with hematoma volume, stroke severity, and 3-month outcomes in patients with acute intracerebral hemorrhage (ICH).
Source: The American Journal of Emergency Medicine - November 16, 2016 Category: Emergency Medicine Authors: Yaming Sun, Shoujiang You, Chongke Zhong, Zhichao Huang, Lifang Hu, Xia Zhang, Jijun Shi, Yongjun Cao, Chun-Feng Liu Source Type: research

Utility of point of care assessment of platelet reactivity (using the PFA-100 ®) to aid in diagnosis of stroke
Rapid and accurate diagnosis of patients presenting with symptoms of stroke is needed to facilitate the timely delivery of proven effective treatment for patients with acute ischemic stroke (AIS).The aim of this study was to determine whether early assessment of platelet reactivity in patients presenting with symptoms of AIS was associated with a diagnosis of AIS, transient ischemic attack (TIA), or stroke mimic.
Source: The American Journal of Emergency Medicine - November 15, 2016 Category: Emergency Medicine Authors: Claire Pearson, Karin Przklenk, Valerie Mika, Syed Imran Ayaz, Morgan Ellis, Preet Varade, Rosa Tolomello, Robert D. Welch Source Type: research

Predictors of early neurological deterioration in acute ischemic stroke
We have greatly enjoyed reading the recently published article by Chung and colleagues [1]. The authors found that early hydration therapy during the acute phase of ischemic stroke with a protocol based on daily monitoring of the BUN/Cr ratio significantly improved clinical outcome and functional independence assessed 3months after stroke.
Source: The American Journal of Emergency Medicine - October 22, 2016 Category: Emergency Medicine Authors: B ülent Özlek, Eda Özlek, Murat Biteker Source Type: research

Serum albumin: a risk of stroke?
In this study, 753 patients with acute first-ever ischemic stroke were enrolled, and 692 patients completed the measurements of recurrent outcome 1 year after stroke through home interviews. The study indicated serum albumin levels of patients with recurrence stroke were significantly lower than those of patients without recurrence (37.07 ±4.21 g/L vs 38.91±3.25 g/L, P
Source: The American Journal of Emergency Medicine - October 21, 2016 Category: Emergency Medicine Authors: Haohui He, Jun Guo Source Type: research

Impact of an emergency medicine pharmacist on time to thrombolysis in acute ischemic stroke: strength of association
We were interested to read the valuable paper by Montgomery K and colleagues that was published in American Journal of Emergency Medicine in Jul. 2016 [1]. In this article, the authors investigated the effect of an Emergency Department (ED) pharmacist on time on thrombolytic administration in acute ischemic stroke patients. The results were very interesting; however, it is important to keep in mind to derive better view from strength of association an emergency medicine pharmacist on time to thrombolysis, we should estimate relative measures such as odds ratio (OR).
Source: The American Journal of Emergency Medicine - October 18, 2016 Category: Emergency Medicine Authors: Saeid Safiri, Mohadeseh Sani, Erfan Ayubi Tags: Correspondence Source Type: research

Favorable outcome of blood urea nitrogen/creatinine-based hydration therapy 3 months after acute ischemic stroke
Dehydration is associated with acute ischemic stroke. However, the relationship between hydration therapy given during acute ischemic stroke and clinical outcomes remains unclear.
Source: The American Journal of Emergency Medicine - September 17, 2016 Category: Emergency Medicine Authors: Jen Lin Chung, Tsung Yang Jen, Chu Huang Yen, Hsiung Tsai Yuan, Ming Hsueh Lee, Meng Lee, Ting Hsiao Cheng, Kuang Yu Hsiao, Leng Chieh Lin Tags: Brief Report Source Type: research

Favorable outcome of blood urea nitrogen/creatinine –based hydration therapy 3 months after acute ischemic stroke
Dehydration is associated with acute ischemic stroke. However, the relationship between hydration therapy given during acute ischemic stroke and clinical outcomes remains unclear.
Source: The American Journal of Emergency Medicine - September 17, 2016 Category: Emergency Medicine Authors: Chung Jen Lin, Jen Tsung Yang, Yen Chu Huang, Yuan Hsiung Tsai, Ming Hsueh Lee, Meng Lee, Cheng Ting Hsiao, Kuang Yu Hsiao, Leng Chieh Lin Tags: Brief Report Source Type: research

Investigation of Oxidant and Antioxidant Levels in Patients with Acute Stroke in the Emergency Service
In this study, we aimed to identify oxidative stress and the disruption in the oxidant-antioxidant balance in the acute phase of stroke, and therefore to detect markers that will guide in the diagnosis and treatment of stroke.
Source: The American Journal of Emergency Medicine - August 30, 2016 Category: Emergency Medicine Authors: İsmail Atik, Nalan Kozacı, İnan Beydilli, Mustafa Avcı, Hamit Ellidağ, Mustafa Keşaplı Tags: Original Contribution Source Type: research

Comprehensive interpretation of hyperglycemia and hyperosmolality on the clinical outcomes among ischemic stroke patients
Hyperglycemia and hyperosmolality are associated with poor outcomes among acute ischemic stroke (AIS) patients.
Source: The American Journal of Emergency Medicine - August 27, 2016 Category: Emergency Medicine Authors: Seunghun Ock, Sion Jo, Jae Baek Lee, Youngho Jin, Taeoh Jeong, Jaechol Yoon, Boyoung Park Source Type: research

Impact of an emergency medicine pharmacist on time to thrombolysis in acute ischemic stroke
The time to thrombolysis, commonly termed “door-to-needle” (DTN) is a measure of stroke center quality and effective patient care. The 2013 American Heart Association/American Stroke Association (AHA/ASA) Guidelines for the Early Management of Patients with Acute Ischemic Stroke recommend that hospitals administer thrombolytics to all eligible ischemic stroke patients in less than 60 minutes from arrival [1]. Time to initiation of thrombolytics in ischemic stroke patients has been associated with improved neurological outcomes, decreased adverse effects, and reduced mortality with early thrombolysis associated with the...
Source: The American Journal of Emergency Medicine - July 6, 2016 Category: Emergency Medicine Authors: Kayla Montgomery, A. Brad Hall, Georgia Keriazes Source Type: research

Serum albumin level is associated with the recurrence of acute ischemic stroke
Previous studies have confirmed that low serum albumin levels in acute ischemic stroke patients increased the risk for poor outcome and death, demonstrating the neuroprotective role of albumin. However, there are few studies investigating the relationship between albumin levels and recurrence of stroke. The aim of this study was to evaluate the effect of serum albumin level on the risk of recurrence in patients with acute ischemic stroke.
Source: The American Journal of Emergency Medicine - June 13, 2016 Category: Emergency Medicine Authors: Qing Zhang, Yi-Xiong Lei, Qiang Wang, Yong-Ping Jin, Rong-Li Fu, He-Hong Geng, Ling-Ling Huang, Xiao-Xiao Wang, Pei-Xi Wang Tags: Original Contribution Source Type: research

Emergency Transport of Stroke Suspects in a Rural State: Opportunities for Improvement
Time delay is the key obstacle for receiving successful stroke treatment. Alteplase therapy must start within 4.5 hours from stroke occurrence. Rapid transport to a Primary Stroke Center (PSC) or Acute Stroke Ready Hospital (ASRH) by the emergency medical system (EMS) paramedics is vital. We determined transport time and destination data for EMS identified and delivered stroke suspects in Arkansas during 2013. Our objective was to analyze transport time and the hospital qualification for stroke care across the state.
Source: The American Journal of Emergency Medicine - June 13, 2016 Category: Emergency Medicine Authors: Aliza T. Brown, Feifei Wei, William C. Culp, Greg Brown, Ryan Tyler, Appathurai Balamurugan, Nicolas Bianchi Tags: Brief Report Source Type: research

Serum albumin level is associated with the recurrence of acute ischemic stroke
Previous studies have confirmed that low serum albumin levels in acute ischemic stroke patients increased the risk for poor outcome and death, demonstrating the neuroprotective role of albumin. However, there are few studies investigating the relationship between albumin levels and recurrence of stroke. The aim of this study was to evaluate the effect of serum albumin level on the risk of recurrence in patients with acute ischemic stroke.
Source: The American Journal of Emergency Medicine - June 13, 2016 Category: Emergency Medicine Authors: Qing Zhang, Yi-Xiong Lei, Qiang Wang, Yong-Ping Jin, Rong-Li Fu, He-Hong Geng, Ling-Ling Huang, Xiao-Xiao Wang, Pei-Xi Wang Tags: Original Contribution Source Type: research

Emergency transport of stroke suspects in a rural state: opportunities for improvement
Time delay is the key obstacle for receiving successful stroke treatment. Alteplase therapy must start within 4.5 hours from stroke occurrence. Rapid transport to a primary stroke center (PSC) or acute stroke –ready hospital (ASRH) by the emergency medical system (EMS) paramedics is vital. We determined transport time and destination data for EMS-identified and -delivered stroke suspects in Arkansas during 2013. Our objective was to analyze transport time and the hospital qualification for stroke care across the state.
Source: The American Journal of Emergency Medicine - June 13, 2016 Category: Emergency Medicine Authors: Aliza T. Brown, Feifei Wei, William C. Culp, Greg Brown, Ryan Tyler, Appathurai Balamurugan, Nicolas Bianchi Tags: Brief Report Source Type: research

Stroke prevention in real-life practice
We have greatly enjoyed reading the recently published article by McIntyre et al [1] . The authors distributed a 16-question, Web-based survey to Canadian residency programs and each scenario involved a 76-year-old man with new atrial fibrillation (AF) and a CHADS2 score of 3. The authors revealed the discordance between clinical guidelines for stroke prevention in AF and the practice of Canadian emergency medicine residents. Despite ranking the risk of adverse events as their most important consideration and the superior safety profile of those non –vitamin K antagonist oral anticoagulants (NOACs), residents underused ...
Source: The American Journal of Emergency Medicine - June 6, 2016 Category: Emergency Medicine Authors: Özcan Başaran, Volkan Doğan, Eda Özlek, Bülent Özlek, Murat Biteker Tags: Correspondence Source Type: research

Stroke Prevention in Real-life Practice
We have greatly enjoyed reading the recently published article by McIntyre et al. (1). The authors distributed a 16-question, web-based survey to Canadian residency programs and each scenario involved a 76-year-old man with new atrial fibrillation (AF) and a CHADS2 score of 3. The authors revealed the discordance between clinical guidelines for stroke prevention in AF and the practice of Canadian emergency medicine residents. Despite ranking the risk of adverse events as their most important consideration and the superior safety profile of that non-vitamin K antagonist oral anticoagulants (NOACs), residents underused this ...
Source: The American Journal of Emergency Medicine - June 6, 2016 Category: Emergency Medicine Authors: Özcan Başaran, Volkan Doğan, Eda Özlek, Bülent Özlek, Murat Biteker Source Type: research

The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke
Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.
Source: The American Journal of Emergency Medicine - June 5, 2016 Category: Emergency Medicine Authors: Suha Turkmen, Ozgen Cekic Gonenc, Yunus Karaca, Ahmet Mentese, Selim Demir, Ercument Beyhun, Aynur Sahin, Abdulkadir Gunduz, Esin Yulug, Suleyman Turedi Source Type: research

The Effect of Ethyl Pyruvate and N-Acetylcysteine on Ischemia Reperfusion Injury in an Experimental Model of Ischemic Stroke
Reperfusion therapies play an important role in early-period treatment of patients presenting to the emergency department due to stroke. However, the ischemia–reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia–reperfusion injury.
Source: The American Journal of Emergency Medicine - June 5, 2016 Category: Emergency Medicine Authors: Turkmen Suha, Cekic Gonenc Ozgen, Karaca Yunus, Mentese Ahmet, Demir Selim, Beyhun Ercument, Sahin Aynur, Gunduz Abdulkadir, Yulug Esin, Turedi Suleyman Source Type: research