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Source: American Journal of Neuroradiology

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Total 281 results found since Jan 2013.

Middle Cerebral Artery Plaque Hyperintensity on T2-Weighted Vessel Wall Imaging Is Associated with Ischemic Stroke ADULT BRAIN
CONCLUSIONS: The MCA plaque hyperintensity on T2-weighted vessel wall imaging is independently associated with ischemic stroke and adds value to symptomatic MCA plaque classification. Measuring the normalized signal intensity may serve as a practical and integrative approach to the analysis of intracranial atherosclerotic plaque.
Source: American Journal of Neuroradiology - November 13, 2019 Category: Radiology Authors: Yu, Y.- N., Liu, M.- W., Villablanca, J. P., Li, M.- L., Xu, Y.- Y., Gao, S., Feng, F., Liebeskind, D. S., Scalzo, F., Xu, W.- H. Tags: ADULT BRAIN Source Type: research

Time to Discontinue Use of the Term "Hemorrhagic Stroke" EDITORIALS
Source: American Journal of Neuroradiology - November 13, 2019 Category: Radiology Authors: Aftab, M., Salman, M. Tags: EDITORIALS Source Type: research

The Fate of Unruptured Intracranial Vertebrobasilar Dissecting Aneurysm with Brain Stem Compression According to Different Treatment Modalities INTERVENTIONAL
CONCLUSIONS: When treating intracranial vertebrobasilar dissecting aneurysms with brain stem compression, parent artery occlusion and flow diversion should be considered to reduce aneurysm size and improve the mRS score.
Source: American Journal of Neuroradiology - November 13, 2019 Category: Radiology Authors: Cho, D. Y., Kim, B.- S., Choi, J. H., Park, Y. K., Shin, Y. S. Tags: INTERVENTIONAL Source Type: research

Diagnostic Impact of Intracranial Vessel Wall MRI in 205 Patients with Ischemic Stroke or TIA ADULT BRAIN
CONCLUSIONS: When vessel wall MR imaging is performed to clarify the etiology of a stroke or TIA, it frequently alters the etiologic classification. This is important because the etiologic classification is the basis for therapeutic decision-making.
Source: American Journal of Neuroradiology - October 8, 2019 Category: Radiology Authors: Schaafsma, J. D., Rawal, S., Coutinho, J. M., Rasheedi, J., Mikulis, D. J., Jaigobin, C., Silver, F. L., Mandell, D. M. Tags: ADULT BRAIN Source Type: research

Impact of Vessel Wall MR Imaging in the Work-Up for Ischemic Stroke COMMENTARIES
Source: American Journal of Neuroradiology - October 8, 2019 Category: Radiology Authors: Song, J. W. Tags: COMMENTARIES Source Type: research

Defining Ischemic Core in Acute Ischemic Stroke Using CT Perfusion: A Multiparametric Bayesian-Based Model ADULT BRAIN
CONCLUSIONS: We established thresholds for the Bayesian model to estimate the ischemic core. The described multiparametric Bayesian-based model improved consistency in CTP estimation of the ischemic core compared with the methodology used in current clinical routine.
Source: American Journal of Neuroradiology - September 4, 2019 Category: Radiology Authors: Nael, K., Tadayon, E., Wheelwright, D., Metry, A., Fifi, J. T., Tuhrim, S., De Leacy, R. A., Doshi, A. H., Chang, H. L., Mocco, J. Tags: ADULT BRAIN Source Type: research

The Association between FLAIR Vascular Hyperintensity and Stroke Outcome Varies with Time from Onset ADULT BRAIN
CONCLUSIONS: FLAIR vascular hyperintensity is associated with unfavorable outcome within 6 hours to 14 days of onset, while the wider distribution of distal FLAIR vascular hyperintensity may be favorable beyond 14 days of onset in MCA infarction. Symptom-to-MR imaging time should be considered when assessing the prognostic value of FLAIR vascular hyperintensity.
Source: American Journal of Neuroradiology - August 14, 2019 Category: Radiology Authors: Shang, W. J., Chen, H. B., Shu, L. M., Liao, H. Q., Huang, X. Y., Xiao, S., Hong, H. Tags: ADULT BRAIN Source Type: research

Leukoaraiosis May Confound the Interpretation of CT Perfusion in Patients Treated with Mechanical Thrombectomy for Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: In patients with stroke, the presence of leukoaraiosis confounds the interpretation of CTP despite proper adjustment of CBF thresholds.
Source: American Journal of Neuroradiology - August 14, 2019 Category: Radiology Authors: Rudilosso, S., Laredo, C., Vivancos, C., Urra, X., Llull, L., Renu, A., Obach, V., Zhao, Y., Moreno, J. L., Lopez-Rueda, A., Amaro, S., Chamorro, A. Tags: INTERVENTIONAL Source Type: research

One-Stop Management with Perfusion for Transfer Patients with Stroke due to a Large-Vessel Occlusion: Feasibility and Effects on In-Hospital Times INTERVENTIONAL
CONCLUSIONS: In this small series, one-stop management with perfusion led to a significant reduction of in-hospital times compared with our previous workflow.
Source: American Journal of Neuroradiology - August 14, 2019 Category: Radiology Authors: Brehm, A., Tsogkas, I., Maier, I. L., Eisenberger, H. J., Yang, P., Liu, J.- M., Liman, J., Psychogios, M.- N. Tags: INTERVENTIONAL Source Type: research

A Novel Collateral Imaging Method Derived from Time-Resolved Dynamic Contrast-Enhanced MR Angiography in Acute Ischemic Stroke: A Pilot Study ADULT BRAIN
CONCLUSIONS: We demonstrated that the dynamic signals of dynamic contrast-enhanced MRA could be used to generate multiphase collateral images and showed the possibility of the multiphase MRA collateral map as a useful collateral imaging method in acute ischemic stroke.
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Roh, H. G., Kim, E. Y., Kim, I. S., Lee, H. J., Park, J. J., Lee, S. B., Choi, J. W., Jeon, Y. S., Park, M., Kim, S. U., Kim, H. J. Tags: ADULT BRAIN Source Type: research

First-Line Sofia Aspiration Thrombectomy Approach within the Endovascular Treatment of Ischemic Stroke Multicentric Registry: Efficacy, Safety, and Predictive Factors of Success INTERVENTIONAL
CONCLUSIONS: The first-line contact aspiration approach appeared safe and efficient with Sofia catheters. These devices achieved very high reperfusion rates with a low requirement for stent retriever rescue therapy, especially for M1 occlusions.
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Marnat, G., Barreau, X., Detraz, L., Bourcier, R., Gory, B., Sgreccia, A., Gariel, F., Berge, J., Menegon, P., Kyheng, M., Labreuche, J., Consoli, A., Blanc, R., Lapergue, B., on behalf of the ETIS Investigators Tags: INTERVENTIONAL Source Type: research

Impact of Balloon-Guiding Catheter Location on Recanalization in Patients with Acute Stroke Treated by Mechanical Thrombectomy INTERVENTIONAL
CONCLUSIONS: Location of the balloon-guiding catheter has a significant impact on recanalization in patients with acute stroke. The balloon-guiding catheter should be positioned as distally as safely possible in the cervical ICA for maximally effective thrombectomy.
Source: American Journal of Neuroradiology - May 15, 2019 Category: Radiology Authors: Jeong, D. E., Kim, J. W., Kim, B. M., Hwang, W., Kim, D. J. Tags: INTERVENTIONAL Source Type: research

Risk of Acute Kidney Injury with Consecutive, Multidose Use of Iodinated Contrast in Patients with Acute Ischemic Stroke PATIENT SAFETY
SUMMARY: Currently, CTA is the imaging technique most frequently used to evaluate acute ischemic stroke, and patients with intracranial large-vessel occlusion usually undergo endovascular treatment. This single-center, prospective, cohort study showed that consecutive, multidose use of contrast during CTA and DSA does not increase the incidence of acute kidney injury in patients with acute ischemic stroke, though acute kidney injury tended to have a higher incidence in the contrast multiexposure group (P = .172).
Source: American Journal of Neuroradiology - April 11, 2019 Category: Radiology Authors: Jia, Z. Y., Wang, S. X., Zhao, L. B., Cao, Y. Z., Shi, H. B., Liu, S. Tags: PATIENT SAFETY Source Type: research

Imaging of Patients with Suspected Large-Vessel Occlusion at Primary Stroke Centers: Available Modalities and a Suggested Approach research-article
SUMMARY: The overwhelming benefit of endovascular therapy in patients with large-vessel occlusions suggests that more patients will be screened than treated. Some of those patients will be evaluated first at primary stroke centers; this type of evaluation calls for standardizing the imaging approach to minimize delays in assessing, transferring, and treating these patients. Here, we propose that CT angiography (performed at the same time as head CT) should be the minimum imaging approach for all patients with stroke with suspected large-vessel occlusion presenting to primary stroke centers. We discuss some of the implicati...
Source: American Journal of Neuroradiology - March 14, 2019 Category: Radiology Authors: Almekhlafi, M. A., Kunz, W. G., Menon, B. K., McTaggart, R. A., Jayaraman, M. V., Baxter, B. W., Heck, D., Frei, D., Derdeyn, C. P., Takagi, T., Aamodt, A. H., Fragata, I. M. R., Hill, M. D., Demchuk, A. M., Goyal, M. Tags: research-article Source Type: research

Aqueductal CSF Stroke Volume Is Increased in Patients with Idiopathic Normal Pressure Hydrocephalus and Decreases after Shunt Surgery ADULT BRAIN
CONCLUSIONS: Aqueductal CSF stroke volume was increased in patients with idiopathic normal pressure hydrocephalus and decreased after shunt surgery, whereas retrograde aqueductal net flow did not seem to be specific for patients with idiopathic normal pressure hydrocephalus. On the basis of the results, the usefulness of CSF flow parameters to predict outcome after shunt surgery seem to be limited.
Source: American Journal of Neuroradiology - March 14, 2019 Category: Radiology Authors: Shanks, J., Markenroth Bloch, K., Laurell, K., Cesarini, K. G., Fahlström, M., Larsson, E.- M., Virhammar, J. Tags: ADULT BRAIN Source Type: research

Focal Hypoperfusion in Acute Ischemic Stroke Perfusion CT: Clinical and Radiologic Predictors and Accuracy for Infarct Prediction ADULT BRAIN
CONCLUSIONS: Compared with NCCT, perfusion CT doubles the sensitivity in detecting acute ischemic stroke. Focal hypoperfusion is independently predicted by stroke severity, cortical clinical deficits, nonlacunar supratentorial strokes, and shorter onset-to-imaging delays. A high proportion of patients with focal hypoperfusion developed infarction on subsequent imaging, as did some patients without focal hypoperfusion, indicating the complementarity of perfusion CT and MR imaging in acute ischemic stroke.
Source: American Journal of Neuroradiology - March 14, 2019 Category: Radiology Authors: Bill, O., Inacio, N. M., Lambrou, D., Wintermark, M., Ntaios, G., Dunet, V., Michel, P. Tags: ADULT BRAIN Source Type: research

Predictors and Clinical Impact of Delayed Stent Thrombosis after Thrombectomy for Acute Stroke with Tandem Lesions INTERVENTIONAL
CONCLUSIONS: We observed a non-negligible rate of delayed stent thrombosis with significant negative impact on clinical outcome. Future studies should systematically measure and report stent patency rates.
Source: American Journal of Neuroradiology - March 14, 2019 Category: Radiology Authors: Pop, R., Zinchenko, I., Quenardelle, V., Mihoc, D., Manisor, M., Richter, J. S., Severac, F., Simu, M., Chibbaro, S., Rouyer, O., Wolff, V., Beaujeux, R. Tags: INTERVENTIONAL Source Type: research

Clinical Outcome after Thrombectomy in Patients with Stroke with Premorbid Modified Rankin Scale Scores of 3 and 4: A Cohort Study with 136 Patients INTERVENTIONAL
CONCLUSIONS: Good outcome in patients with premorbid mRS 3 and 4 is less frequent compared with premorbid mRS 0–2. Nevertheless, about 20% of the patients return to their premorbid mRS, which may justify endovascular treatment. The most important predictor of good outcome is successful recanalization.
Source: American Journal of Neuroradiology - February 13, 2019 Category: Radiology Authors: Seker, F., Pfaff, J., Schönenberger, S., Herweh, C., Nagel, S., Ringleb, P. A., Bendszus, M., Möhlenbruch, M. A. Tags: INTERVENTIONAL Source Type: research

Automated ASPECTS on Noncontrast CT Scans in Patients with Acute Ischemic Stroke Using Machine Learning FUNCTIONAL
CONCLUSIONS: The proposed automated ASPECTS scoring approach shows reasonable ability to determine ASPECTS on NCCT images in patients presenting with acute ischemic stroke.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Kuang, H., Najm, M., Chakraborty, D., Maraj, N., Sohn, S. I., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K., Qiu, W. Tags: FUNCTIONAL Source Type: research

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke FUNCTIONAL
CONCLUSIONS: Thrombus radiomics features derived from NCCT and CTA are more predictive of recanalization with IV alteplase in patients with acute ischemic stroke with proximal occlusion than previously known thrombus imaging features such as length, volume, and permeability.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Qiu, W., Kuang, H., Nair, J., Assis, Z., Najm, M., McDougall, C., McDougall, B., Chung, K., Wilson, A. T., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K. Tags: FUNCTIONAL Source Type: research

Infarct Volume Predicts Hospitalization Costs in Anterior Circulation Large-Vessel Occlusion Stroke ADULT BRAIN
CONCLUSIONS: Final infarct volume was the strongest predictor of increased hospitalization costs in anterior circulation large-vessel occlusion stroke. Acute stroke therapies that reduce final infarct volume may not only improve clinical outcomes but may also prove cost-effective.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Streib, C. D., Rangaraju, S., Campbell, D. T., Winger, D. G., Paolini, S. L., Zhang, A. J., Jankowitz, B. T., Jadhav, A. P., Jovin, T. G. Tags: ADULT BRAIN Source Type: research

Two-Layered Susceptibility Vessel Sign and High Overestimation Ratio on MRI Are Predictive of Cardioembolic Stroke ADULT BRAIN
SUMMARY: In a prospective study among patients in the THRombectomie des Artères Cerebrales trial, we analyzed the diagnostic accuracy of 2 imaging biomarkers, the 2-layered susceptibility vessel sign and a high overestimation ratio, obtained on pretreatment brain T2* sequences, to identify cardioembolic stroke etiology (107/260 patients). In combination, these 2 biomarkers, on 1.5T or 3T systems (159 and 101 patients, respectively), demonstrated high specificity (0.77 at 1.5T and 1 at 3T) and their simultaneous presence is highly associated with cardioembolism.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Bourcier, R., Derraz, I., Bracard, S., Oppenheim, C., Naggara, O., on behalf of the THRACE Investigators Tags: ADULT BRAIN Source Type: research

MR Imaging for Differentiating Contrast Staining from Hemorrhagic Transformation after Endovascular Thrombectomy in Acute Ischemic Stroke: Phantom and Patient Study ADULT BRAIN
CONCLUSIONS: According to our preliminary results, contrast staining might be differentiated from hemorrhagic transformation using an immediate postinterventional DWI protocol including gradient recalled-echo sequences. It might be possible to expedite establishment of postinterventional medical treatment strategy.
Source: American Journal of Neuroradiology - December 14, 2018 Category: Radiology Authors: You, S.- H., Kim, B., Kim, B. K., Suh, S.- i. Tags: ADULT BRAIN Source Type: research

Impact of Ischemic Lesion Location on the mRS Score in Patients with Ischemic Stroke: A Voxel-Based Approach ADULT BRAIN
CONCLUSIONS: Our study confirms that infarct location has an important impact on functional outcome of patients with stroke and should be considered in prediction models. After we adjusted for covariates, the left-hemispheric corticosubcortical fiber tracts seemed to be of higher functional importance compared with cortical lesions.
Source: American Journal of Neuroradiology - November 15, 2018 Category: Radiology Authors: Ernst, M., Boers, A. M. M., Forkert, N. D., Berkhemer, O. A., Roos, Y. B., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Vettorazzi, E., Fiehler, J., Marquering, H. A., Majoie, C. B. L. M., Gellissen, S., on behalf of the M Tags: ADULT BRAIN Source Type: research

Value of Contrast-Enhanced MRA versus Time-of-Flight MRA in Acute Ischemic Stroke MRI ADULT BRAIN
CONCLUSIONS: Contrast-enhanced MRA offers better diagnostic accuracy than TOF-MRA in acute ischemic stroke. Contrast-enhanced MRA was superior in localizing vessel occlusion within a shorter acquisition time while providing a larger coverage, including extracranial vessels, and a more accurate assessment of collateral status. These results support inclusion of contrast-enhanced MRA in acute stroke MR imaging, perhaps making TOF-MRA superfluous.
Source: American Journal of Neuroradiology - September 6, 2018 Category: Radiology Authors: Boujan, T., Neuberger, U., Pfaff, J., Nagel, S., Herweh, C., Bendszus, M., Möhlenbruch, M. A. Tags: ADULT BRAIN Source Type: research

Time Course of Cerebral Perfusion Changes in Children with Migraine with Aura Mimicking Stroke PEDIATRICS
We present 12 pediatric patients with acute hemiplegic migraine or migraine with aura who underwent MR imaging within 12 hours of symptom onset. Quantitative and qualitative analyses were performed on arterial spin-labeling; and qualitative analysis, on SWI and MRA sequences. All 12 patients had normal DWI and abnormal arterial spin-labeling findings. Furthermore, we observed a more rapid transition from hypoperfusion to rebound hyperperfusion in 3 patients compared with prior reports. These findings support the use of multimodal MR imaging to distinguish migraine with aura from stroke and the simultaneous use of these MR ...
Source: American Journal of Neuroradiology - September 6, 2018 Category: Radiology Authors: Cobb-Pitstick, K. M., Munjal, N., Safier, R., Cummings, D. D., Zuccoli, G. Tags: PEDIATRICS Source Type: research

Mobile Stroke Unit Reduces Time to Image Acquisition and Reporting INTERVENTIONAL
SUMMARY: Timely administration of thrombolytic therapy is critical to maximizing the likelihood of favorable outcomes in patients with acute ischemic stroke. Although emergency medical service activation overall improves the timeliness of acute stroke treatment, the time from emergency medical service dispatch to hospital arrival unavoidably decreases the timeliness of thrombolytic administration. Our mobile stroke unit, a new-generation ambulance with on-board CT scanning capability, reduces key imaging time metrics and facilitates in-the-field delivery of IV thrombolytic therapy.
Source: American Journal of Neuroradiology - July 9, 2018 Category: Radiology Authors: Nyberg, E. M., Cox, J. R., Kowalski, R. G., Vela-Duarte, D., Schimpf, B., Jones, W. J. Tags: INTERVENTIONAL Source Type: research

Value of Quantitative Collateral Scoring on CT Angiography in Patients with Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: Automated quantitative collateral scoring in patients with acute ischemic stroke is a reliable and user-independent measure of the collateral capacity on baseline CTA and has the potential to augment the triage of patients with acute stroke for endovascular therapy.
Source: American Journal of Neuroradiology - June 13, 2018 Category: Radiology Authors: Boers, A. M. M., Sales Barros, R., Jansen, I. G. H., Berkhemer, O. A., Beenen, L. F. M., Menon, B. K., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Slump, C. H., Majoie, C. B. L. M., Marquering, H. A. Tags: ADULT BRAIN Source Type: research

Clinical Outcomes of Endovascular Treatment within 24 Hours in Patients with Mild Ischemic Stroke and Perfusion Imaging Selection INTERVENTIONAL
CONCLUSIONS: Patients with mild ischemic stroke and large-vessel occlusion in the anterior circulation, an imaging mismatch, and endovascular treatment within 6–24 hours of initial symptoms showed no heterogeneity in the efficacy and safety outcome compared with those treated ≤6 hours from symptom onset.
Source: American Journal of Neuroradiology - June 13, 2018 Category: Radiology Authors: Shang, X., Lin, M., Zhang, S., Li, S., Guo, Y., Wang, W., Zhang, M., Wan, Y., Zhou, Z., Zi, W., Liu, X. Tags: INTERVENTIONAL Source Type: research

Multicentric Experience in Distal-to-Proximal Revascularization of Tandem Occlusion Stroke Related to Internal Carotid Artery Dissection INTERVENTIONAL
CONCLUSIONS: Endovascular treatment of internal carotid dissection–related tandem occlusion stroke using the distal-to-proximal recanalization strategy appears to be feasible, with low complication rates and considerable rates of successful recanalization.
Source: American Journal of Neuroradiology - June 13, 2018 Category: Radiology Authors: Marnat, G., Bühlmann, M., Eker, O. F., Gralla, J., Machi, P., Fischer, U., Riquelme, C., Arnold, M., Bonafe, A., Jung, S., Costalat, V., Mordasini, P. Tags: INTERVENTIONAL Source Type: research

Endovascular Management of Acute Stroke in the Elderly: A Systematic Review and Meta-Analysis ADULT BRAIN
Conclusions: Good functional recovery in octogenarians treated with endovascular therapy for acute stroke can be achieved in a high proportion of patients despite the higher incidence of comorbidity in this cohort. Outcomes are inferior to those reported for younger patients; however, endovascular therapy can allow at least 1 in 4 patients older than 80 years of age to regain independent function at 3 months. More research is required to improve patient selection in the elderly, but age should not be a discriminator when deciding to offer endovascular therapy for patients with acute stroke.
Source: American Journal of Neuroradiology - May 15, 2018 Category: Radiology Authors: Hilditch, C. A., Nicholson, P., Murad, M. H., Rabinstein, A., Schaafsma, J., Pikula, A., Krings, T., Pereira, V. M., Agid, R., Brinjikji, W. Tags: ADULT BRAIN Source Type: research

Accuracy of CT Angiography for Differentiating Pseudo-Occlusion from True Occlusion or High-Grade Stenosis of the Extracranial ICA in Acute Ischemic Stroke: A Retrospective MR CLEAN Substudy INTERVENTIONAL
CONCLUSIONS: On CTA, extracranial ICA pseudo-occlusions can be differentiated from true carotid occlusions.
Source: American Journal of Neuroradiology - May 15, 2018 Category: Radiology Authors: Kappelhof, M., Marquering, H. A., Berkhemer, O. A., Borst, J., van der Lugt, A., van Zwam, W. H., Vos, J. A., Lycklama a Nijeholt, G., Majoie, C. B. L. M., Emmer, B. J., on behalf of the MR CLEAN Investigators Tags: INTERVENTIONAL Source Type: research

Randomized Assessment of the Safety and Efficacy of Intra-Arterial Infusion of Autologous Stem Cells in Subacute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: Intra-arterial infusion of stem cells can be carried out safely in the subacute stage of ischemic stroke. Improved clinical outcomes were observed with intra-arterial stem cell therapy; however, studies with larger cohorts are needed to validate the results.
Source: American Journal of Neuroradiology - May 15, 2018 Category: Radiology Authors: Bhatia, V., Gupta, V., Khurana, D., Sharma, R. R., Khandelwal, N. Tags: INTERVENTIONAL Source Type: research

Prediction of the Multisegment Clot Sign on Dynamic CT Angiography of Cardioembolic Stroke ADULT BRAIN
CONCLUSIONS: The presence of the multisegment clot sign on dynamic CTA specifically indicates intracranial large-artery occlusion caused by an embolism from a cardiac source, which may be useful for acute management and secondary prevention of stroke.
Source: American Journal of Neuroradiology - April 10, 2018 Category: Radiology Authors: Chen, Z., Shi, F., Zhang, M., Gong, X., Lin, L., Lou, M. Tags: ADULT BRAIN Source Type: research

Iodine Extravasation Quantification on Dual-Energy CT of the Brain Performed after Mechanical Thrombectomy for Acute Ischemic Stroke Can Predict Hemorrhagic Complications INTERVENTIONAL
CONCLUSIONS: The presence of parenchymal hyperdensity with a maximum iodine concentration of >1.35 mg/mL may identify patients developing intracerebral hemorrhage with 100% sensitivity and 67.6% specificity.
Source: American Journal of Neuroradiology - March 14, 2018 Category: Radiology Authors: Bonatti, M., Lombardo, F., Zamboni, G. A., Vittadello, F., Curro Dossi, R., Bonetti, B., Pozzi Mucelli, R., Bonatti, G. Tags: INTERVENTIONAL Source Type: research

Endovascular Thrombectomy in Wake-Up Stroke and Stroke with Unknown Symptom Onset INTERVENTIONAL
CONCLUSIONS: Mechanical thrombectomy in selected patients with wake-up stroke allows a good functional outcome comparable with that of controls. Outcome after mechanical thrombectomy in daytime-unwitnessed stroke seems to be inferior compared with that in controls. Advanced imaging modalities may increase the frequency of good functional outcome in both patients with wake-up stroke and daytime-unwitnessed stroke.
Source: American Journal of Neuroradiology - March 14, 2018 Category: Radiology Authors: Bücke, P., Perez, M. A., Hellstern, V., AlMatter, M., Bäzner, H., Henkes, H. Tags: INTERVENTIONAL Source Type: research

John Nash and the Organization of Stroke Care research-article
SUMMARY: The concept of Nash equilibrium, developed by John Forbes Nash Jr, states that an equilibrium in noncooperative games is reached when each player takes the best action for himself or herself, taking into account the actions of the other players. We apply this concept to the provision of endovascular thrombectomy in the treatment of acute ischemic stroke and suggest that collaboration among hospitals in a health care jurisdiction could result in practices such as shared call pools for neurointervention teams, leading to better patient care through streamlined systems.
Source: American Journal of Neuroradiology - February 13, 2018 Category: Radiology Authors: Goyal, M., Wilson, A. T., Mayank, D., Kamal, N., Robinson, D. H., Turkel-Parrella, D., Hirsch, J. A. Tags: research-article Source Type: research

MR Perfusion to Determine the Status of Collaterals in Patients with Acute Ischemic Stroke: A Look Beyond Time Maps ADULT BRAIN
CONCLUSIONS: The Perfusion Collateral Index can predict the baseline collateral status with 94% diagnostic accuracy compared with DSA.
Source: American Journal of Neuroradiology - February 13, 2018 Category: Radiology Authors: Nael, K., Doshi, A., De Leacy, R., Puig, J., Castellanos, M., Bederson, J., Naidich, T. P., Mocco, J., Wintermark, M. Tags: ADULT BRAIN Source Type: research

Clinical and Imaging Characteristics of Arteriopathy Subtypes in Children with Arterial Ischemic Stroke: Results of the VIPS Study PEDIATRICS
CONCLUSIONS: Childhood arteriopathy subtypes have some typical features that aid diagnosis. Better imaging methods, including vessel wall imaging, are needed for improved classification of focal cerebral arteriopathy of childhood.
Source: American Journal of Neuroradiology - November 15, 2017 Category: Radiology Authors: Wintermark, M., Hills, N. K., DeVeber, G. A., Barkovich, A. J., Bernard, T. J., Friedman, N. R., Mackay, M. T., Kirton, A., Zhu, G., Leiva-Salinas, C., Hou, Q., Fullerton, H. J., the VIPS Investigators Tags: PEDIATRICS Source Type: research

Transient Focal Neurologic Symptoms Correspond to Regional Cerebral Hypoperfusion by MRI: A Stroke Mimic in Children PEDIATRICS
We present a series of 16 children who presented with transient focal neurologic symptoms that raised concern for acute stroke but who had no evidence of infarction and had unilateral, potentially reversible imaging features on vascular and perfusion-sensitive brain MR imaging. Patients were examined with routine brain MR imaging, MRA, perfusion-sensitive sequences, and DWI. Fourteen (88%) children had lateralized MRA evidence of arterial tree pruning without occlusion, all had negative DWI findings, and all showed evidence of hemispheric hypoperfusion by susceptibility-weighted imaging or arterial spin-labeling perfusion ...
Source: American Journal of Neuroradiology - November 15, 2017 Category: Radiology Authors: Lehman, L. L., Danehy, A. R., Trenor, C. C., Calahan, C. F., Bernson-Leung, M. E., Robertson, R. L., Rivkin, M. J. Tags: PEDIATRICS Source Type: research

Anterior Circulation Acute Ischemic Stroke Associated with Atherosclerotic Lesions of the Cervical ICA: A Nosologic Entity Apart ADULT BRAIN
CONCLUSIONS: Our study suggests that atherothrombotic tandem occlusions represent a peculiar and different nosologic entity compared with dissection-related tandem occlusions. This challenging cause of acute ischemic stroke should be differentiated from other etiologies in patient management in future prospective studies.
Source: American Journal of Neuroradiology - November 15, 2017 Category: Radiology Authors: Eker, O. F., Panni, P., Dargazanli, C., Marnat, G., Arquizan, C., Machi, P., Mourand, I., Gascou, G., Le Bars, E., Costalat, V., Bonafe, A. Tags: ADULT BRAIN Source Type: research

Age, Sex, and Racial Differences in Neuroimaging Use in Acute Stroke: A Population-Based Study ADULT BRAIN
CONCLUSIONS: Within a large, biracial stroke/TIA population, there is variation in the use of advanced neuroimaging by age and race, depending on the care center type.
Source: American Journal of Neuroradiology - October 6, 2017 Category: Radiology Authors: Vagal, A., Sanelli, P., Sucharew, H., Alwell, K. A., Khoury, J. C., Khatri, P., Woo, D., Flaherty, M., Kissela, B. M., Adeoye, O., Ferioli, S., De Los Rios La Rosa, F., Martini, S., Mackey, J., Kleindorfer, D. Tags: ADULT BRAIN Source Type: research

The Use and Utility of Aspiration Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis INTERVENTIONAL
CONCLUSIONS: ADAPT and aspiration thrombectomy are effective approaches to thrombectomy, with high recanalization rates and excellent clinical outcomes reported in the literature. Aspiration thrombectomy is a promising neurointervention, but large prospective randomized studies are needed to validate its utility.
Source: American Journal of Neuroradiology - October 6, 2017 Category: Radiology Authors: Wei, D., Mascitelli, J. R., Nistal, D. A., Kellner, C. P., Fifi, J. T., Mocco, J. D., De Leacy, R. A. Tags: INTERVENTIONAL Source Type: research

Focal Low and Global High Permeability Predict the Possibility, Risk, and Location of Hemorrhagic Transformation following Intra-Arterial Thrombolysis Therapy in Acute Stroke INTERVENTIONAL
CONCLUSIONS: Global high Ktrans values can predict the likelihood of hemorrhagic transformation or symptomatic intracranial hemorrhage at the patient level, whereas focal low Ktrans values can predict the spatial distributions of hemorrhagic transformation at the region level.
Source: American Journal of Neuroradiology - September 8, 2017 Category: Radiology Authors: Li, Y., Xia, Y., Chen, H., Liu, N., Jackson, A., Wintermark, M., Zhang, Y., Hu, J., Wu, B., Zhang, W., Tu, J., Su, Z., Zhu, G. Tags: INTERVENTIONAL Source Type: research

Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: In our study on patients with large-vessel occlusion of the anterior circulation, CT thrombus characteristics appear useful for predicting functional outcome. However, in our study cohort, the effect of intra-arterial treatment was independent of the thrombus CT characteristics. Therefore, no arguments were provided to select patients for intra-arterial treatment using thrombus CT characteristics.
Source: American Journal of Neuroradiology - September 8, 2017 Category: Radiology Authors: Borst, J., Berkhemer, O. A., Santos, E. M. M., Yoo, A. J., den Blanken, M., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., on behal Tags: ADULT BRAIN Source Type: research

CT Angiography ASPECTS Predicts Outcome Much Better Than Noncontrast CT in Patients with Stroke Treated Endovascularly INTERVENTIONAL
CONCLUSIONS: CTA source image ASPECTS predicts outcome better than NCCT ASPECTS; this finding suggests CTA rather than NCCT as a main step in the decision-making process for patients with acute ischemic stroke.
Source: American Journal of Neuroradiology - August 14, 2017 Category: Radiology Authors: Sallustio, F., Motta, C., Pizzuto, S., Diomedi, M., Rizzato, B., Panella, M., Alemseged, F., Stefanini, M., Fabiano, S., Gandini, R., Floris, R., Stanzione, P., Koch, G. Tags: INTERVENTIONAL Source Type: research

The Impact of Conscious Sedation versus General Anesthesia for Stroke Thrombectomy on the Predictive Value of Collateral Status: A Post Hoc Analysis of the SIESTA Trial INTERVENTIONAL
CONCLUSIONS: The sedation mode, conscious sedation or general anesthesia, did not influence the predictive value of collaterals in patients with large-vessel occlusion anterior circulation stroke undergoing thrombectomy in the SIESTA trial.
Source: American Journal of Neuroradiology - August 14, 2017 Category: Radiology Authors: Schönenberger, S., Pfaff, J., Uhlmann, L., Klose, C., Nagel, S., Ringleb, P. A., Hacke, W., Kieser, M., Bendszus, M., Möhlenbruch, M. A., Bösel, J. Tags: INTERVENTIONAL Source Type: research

Effect of Retrievable Stent Size on Endovascular Treatment of Acute Ischemic Stroke: A Multicenter Study INTERVENTIONAL
CONCLUSIONS: We found no evidence of a differential effect of intra-arterial therapy based on the size of Solitaire retrievers. In patients with atherosclerotic disease, favorable reperfusion was associated with deployment of a small stent.
Source: American Journal of Neuroradiology - August 14, 2017 Category: Radiology Authors: Yang, D., Hao, Y., Zi, W., Wang, H., Zheng, D., Li, H., Tu, M., Wan, Y., Jin, P., Xiao, G., Xiong, Y., Xu, G., Liu, X. Tags: INTERVENTIONAL Source Type: research

Diffusional Kurtosis Imaging and Motor Outcome in Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: This study was designed to be one of hypothesis generation. Diffusion metrics related to kurtosis were found to be more sensitive than conventional diffusivity metrics to early poststroke corticospinal tract microstructural changes and may have potential value in the prediction of motor impairment at 3 months.
Source: American Journal of Neuroradiology - July 12, 2017 Category: Radiology Authors: Spampinato, M. V., Chan, C., Jensen, J. H., Helpern, J. A., Bonilha, L., Kautz, S. A., Nietert, P. J., Feng, W. Tags: ADULT BRAIN Source Type: research

Predictors of Reperfusion in Patients with Acute Ischemic Stroke BRAIN
CONCLUSIONS: Recanalization and reperfusion are strongly associated but not always equivalent in ischemic stroke. A smaller total ischemic area is the only independent predictor of complete reperfusion.
Source: American Journal of Neuroradiology - June 11, 2015 Category: Radiology Authors: Horsch, A. D., Dankbaar, J. W., Niesten, J. M., van Seeters, T., van der Schaaf, I. C., van der Graaf, Y., Mali, W. P. T. M., Velthuis, B. K., on behalf of the Dutch Acute Stroke Study Investigators Tags: BRAIN Source Type: research