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Source: European Heart Journal

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Total 332 results found since Jan 2013.

Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)
ConclusionPatients benefit from early, in-hospital initiation of colchicine after MI.Trial RegistrationCOLCOT ClinicalTrials.gov number, NCT02551094.
Source: European Heart Journal - August 29, 2020 Category: Cardiology Source Type: research

Edoxaban in atrial fibrillation patients with percutaneous coronary intervention by acute or chronic coronary syndrome presentation: a pre-specified analysis of the ENTRUST-AF PCI trial
Conclusions  In patients with AF who underwent PCI, the edoxaban-based regimen, as compared with VKA-based regimen, provides consistent safety and similar efficacy for ischaemic events in patients with AF regardless of their clinical presentation.
Source: European Heart Journal - August 29, 2020 Category: Cardiology Source Type: research

Effect of alirocumab on major adverse cardiovascular events according to renal function in patients with a recent acute coronary syndrome: prespecified analysis from the ODYSSEY OUTCOMES randomized clinical trial
ConclusionsIn patients with recent ACS, alirocumab was associated with fewer cardiovascular events and deaths across the range of renal function studied, with larger relative risk reductions in those with eGFR  >  60 mL/min/1.73 m2.
Source: European Heart Journal - August 21, 2020 Category: Cardiology Source Type: research

Variable rate of stroke after transcatheter aortic valve replacement with self-expandable valves: more doubts than certainties
This commentary refers to ‘Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial’ by H. Thieleet al., 2020;41:1890 –1899.
Source: European Heart Journal - August 18, 2020 Category: Cardiology Source Type: research

Stroke rates after transcatheter aortic valve replacement: does valve choice play a role?
This commentary refers to ‘Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial’, by H. Thieleet al., 2020;41:1890 –1899.
Source: European Heart Journal - August 18, 2020 Category: Cardiology Source Type: research

Genetic predisposition to smoking in relation to 14 cardiovascular diseases
ConclusionThis MR study supports a causal association between smoking and a broad range of CVDs, in particular, coronary artery disease, heart failure, abdominal aortic aneurysm, ischaemic stroke, transient ischaemic attack, peripheral arterial disease, and arterial hypertension.
Source: European Heart Journal - April 16, 2020 Category: Cardiology Source Type: research

Supracardiac atherosclerosis in embolic stroke of undetermined source: the underestimated source
AbstractThe term ‘embolic stroke of undetermined source’ (ESUS) is used to describe patients with a non-lacunar ischaemic stroke without any identified embolic source from the heart or the arteries supplying the ischaemic territory, or any other apparent cause. When the ESUS concept was introduced, covert atrial fibrillation was conceived to be the main underlying cause in the majority of ESUS patients. Another important embolic source in ESUS is the atherosclerotic plaque in the carotid, vertebrobasilar, and intracranial arteries, or the aortic arch—collectively described as supracardiac atherosclerosis . There is e...
Source: European Heart Journal - April 16, 2020 Category: Cardiology Source Type: research

Effects of glucagon-like peptide-1 receptor agonists on major cardiovascular events in patients with Type 2 diabetes mellitus with or without established cardiovascular disease: a meta-analysis of randomized controlled trials
Conclusion  Glucagon-like peptide-1 receptor agonists significantly reduce MACE, CV and total mortality stroke, and hospitalization for HF, with a trend for reduction of MI, in patients with Type 2 DM with and without established CVD.
Source: European Heart Journal - February 20, 2020 Category: Cardiology Source Type: research

Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial
ConclusionRoutine ingestion by hypertensive patients of ≥1 prescribed BP-lowering medications at bedtime, as opposed to upon waking, results in improved ABP control (significantly enhanced decrease in asleep BP and increased sleep-time relative BP decline, i.e. BP dipping) and, most importantly, markedly diminished occurrence of major CVD events.Trial registrationClinicalTrials.gov, number NCT00741585. 
Source: European Heart Journal - October 22, 2019 Category: Cardiology Source Type: research

Oral Anticoagulation in patients with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1A current opinion of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and European Society of Cardiology Council on Stroke
Source: European Heart Journal - September 21, 2019 Category: Cardiology Source Type: research

Corrigendum to: Risk stratification for stroke in atrial fibrillation: incorporating neurologists in the comprehensive management
[Eur Heart J 2019;40:3058 –3059].
Source: European Heart Journal - August 19, 2019 Category: Cardiology Source Type: research

Endomyocardial fibrosis and apical thrombus in patient with hypereosinophilia
A 76-year-old woman with a history of left semiovale ischaemic lacunar stroke was admitted to hospital for suspected acute coronary syndrome and transient ischaemic attack. The previous year, echocardiography had shown normal results. Neither coronarography nor encephalic computed tomography showed significant lesions. Brain magnetic resonance imaging revealed multiple strokes in different arterial regions, with probable cardioembolic origin (Panel A).
Source: European Heart Journal - July 30, 2019 Category: Cardiology Source Type: research

Risk stratification for stroke in atrial fibrillation: incorporating neurologists in the comprehensive management
This commentary refers to ‘Risk stratification for stroke in atrial fibrillation: a critique’, by A.M. Killuet al., 2019;40:1294 –1302.
Source: European Heart Journal - July 13, 2019 Category: Cardiology Source Type: research

Response to: Risk stratification for stroke in atrial fibrillation: incorporating neurologists in the comprehensive management
This commentary refers to ‘Risk stratification for stroke in atrial fibrillation: incorporating neurologists in the comprehensive management’†, by H.-F. Liet al., 2019;40:3058 –3059.
Source: European Heart Journal - July 13, 2019 Category: Cardiology Source Type: research

Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index
ConclusionAmong postmenopausal women with normal BMI, both elevated trunk fat and reduced leg fat are associated with increased risk of CVD.
Source: European Heart Journal - June 30, 2019 Category: Cardiology Source Type: research