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Source: European Heart Journal
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Total 332 results found since Jan 2013.
Corrigendum to: Interdisciplinary management of acute ischaemic stroke: Current evidence training requirements for endovascular stroke treatment: Position Paper from the ESC Council on Stroke and the European Association for Percutaneous Cardiovascular Interventions with the support of the European Board of Neurointervention
Source: European Heart Journal - December 22, 2020 Category: Cardiology Source Type: research
Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms
Conclusion Our data implicate early B-cell activation and autoantibodies as a central cause for accelerated atherosclerosis post-MI and identifies novel therapeutic strategies towards preventing recurrent cardiovascular events such as MI and stroke.
Source: European Heart Journal - December 18, 2020 Category: Cardiology Source Type: research
Vegetarians, fish, poultry, and meat-eaters: who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank
Conclusion Eating fish rather than meat or poultry was associated with a lower risk of a range of adverse cardiovascular outcomes. Vegetarianism was only associated with a lower risk of CVD incidence.
Source: European Heart Journal - December 14, 2020 Category: Cardiology Source Type: research
Short dual antiplatelet therapy followed by P2Y12 inhibitor monotherapy vs. prolonged dual antiplatelet therapy after percutaneous coronary intervention with second-generation drug-eluting stents: a systematic review and meta-analysis of randomized clinical trials
ConclusionAfter second-generation DES implantation, 1 –3 months of DAPT followed by P2Y12 inhibitor SAPT is associated with lower major bleeding and similar stent thrombosis, all-cause death, myocardial infarction, and stroke compared with prolonged DAPT. Whether P2Y12 inhibitor SAPT is preferable to aspirin SAPT needs further investigation.
Source: European Heart Journal - December 7, 2020 Category: Cardiology Source Type: research
Coronary flow velocity reserve predicts adverse prognosis in women with angina and no obstructive coronary artery disease: results from the iPOWER study
Conclusion Assessment of CFVR by echocardiography is feasible and predictive of adverse outcome in women with angina and no obstructive CAD. Results support a more aggressive preventive management of these patients and underline the need for trials targeting CMD.
Source: European Heart Journal - December 1, 2020 Category: Cardiology Source Type: research
Late device-related thrombus after left atrial appendage closure: never let your guard down
Left atrial appendage closure (LAAC) is an established strategy for stroke prevention in patients with non-valvular atrial fibrillation and contraindications for oral anticoagulation. Device-related thrombus (DRT) is a feared short-term complication with an incidence of 4 –17%. Data regarding the likelihood of late DRT are scarce.
Source: European Heart Journal - November 12, 2020 Category: Cardiology Source Type: research
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1): a crucial driver of atherosclerotic cardiovascular disease
We describe recent findings from basic research, delineate their translational value, and discuss the potential of LOX-1 as a novel target for the prevention, diagnosis, and treatment of related CVDs.
Source: European Heart Journal - November 7, 2020 Category: Cardiology Source Type: research
Interdisciplinary management of acute ischaemic stroke: Current evidence training requirements for endovascular stroke treatment: Position Paper from the ESC Council on Stroke and the European Association for Percutaneous Cardiovascular Interventions with the support of the European Board of Neurointervention
AbstractThis ESC Council on Stroke/EAPCI/EBNI position paper summarizes recommendations for training of cardiologists in endovascular treatment of acute ischaemic stroke. Interventional cardiologists adequately trained to perform endovascular stroke interventions could complement stroke teams to provide the 24/7 on call duty and thus to increase timely access of stroke patients to endovascular treatment. The training requirements for interventional cardiologists to perform endovascular therapy are described in details and should be based on two main principles: (i) patient safety cannot be compromised, (ii) proper training...
Source: European Heart Journal - November 7, 2020 Category: Cardiology Source Type: research
Low-Dose Edoxaban for Stroke Prevention in Elderly Patients with Atrial Fibrillation: Comment on the Edoxaban Low-Dose for Elder Care Atrial Fibrillation Patients (ELDERCARE-AF) Trial
Results of the ELDERCARE-AF trial have been presented at the ESC Congress 2020 and simultaneously published in theNew England Journal of Medicine (https://doi.org/10.1056/NEJMoa2012883).
Source: European Heart Journal - November 4, 2020 Category: Cardiology Source Type: research
Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes: TWILIGHT-ACS
Conclusion Among patients with or without NSTE-ACS who have completed an initial 3-month course of DAPT following PCI with DES, ticagrelor monotherapy reduced clinically meaningful bleeding events without increasing ischaemic risk as compared with ticagrelor plus aspirin. The benefits of ticagrelor monotherapy with respect to bleeding events were more pronounced in patients with NSTE-ACS.Trial registrationClinicaltrials.gov identifier: NCT02270242.
Source: European Heart Journal - October 20, 2020 Category: Cardiology Source Type: research
Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial
ConclusionBaseline lipoprotein(a) predicted the risk of total cardiovascular events and risk reduction by alirocumab. Lipoprotein(a) lowering contributed independently to cardiovascular event reduction, supporting the concept of lipoprotein(a) as a treatment target after ACS.
Source: European Heart Journal - October 14, 2020 Category: Cardiology Source Type: research
Less dementia after catheter ablation for atrial fibrillation: a nationwide cohort study
ConclusionIn this nationwide cohort of AF patients treated with catheter ablation or medical therapy, ablation was associated with decreased dementia risk. This relationship was evident after censoring for stroke and adjusting for clinical confounders.
Source: European Heart Journal - October 6, 2020 Category: Cardiology Source Type: research
Gone with wind: a novel biodegradable occluder for percutaneous closure of patent foramen ovale
A 42-year-old man with a history of cryptogenic stroke and sequela free after medical therapy was found to have a patent foramen ovale (PFO) by transoesophageal echocardiography (TEE,Panel A, arrowhead indicates the PFO; Ao, aorta; LA, left atrium; RA, right atrium). Given a RoPE score of 7, he was referred for percutaneous PFO closure. A 24 mm × 24 mm fully biodegradable occluder (Pancy® occluder, ChiCTR1900024036,Panel E, arrowhead indicates marker) was delivered and deployed via a 10-Fr sheath (Mallow® delivery system) under florescent angiography and TEE (Panel B, arrowhead indicates the marker on occluder while ...
Source: European Heart Journal - October 2, 2020 Category: Cardiology Source Type: research
Prevalence, incidence, and outcomes across cardiovascular diseases in homeless individuals using national linked electronic health records
Conclusion CVD in homeless individuals has high prevalence, incidence, and 1-year mortality risk post-diagnosis with earlier onset, and high burden of risk factors. Inclusion health and social care strategies should reflect this high preventable and treatable burden, which is increasingly important in the current COVID-19 context.
Source: European Heart Journal - September 10, 2020 Category: Cardiology Source Type: research
The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial
Conclusions Although BAMI is the largest trial of autologous cell-based therapy in the treatment of AMI, unexpectedly low recruitment and event rates preclude any meaningful group comparisons and interpretation of the observed results.
Source: European Heart Journal - August 30, 2020 Category: Cardiology Source Type: research
