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Drug: Prednisone

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Total 40 results found since Jan 2013.

High-Dose Prednisolone for Treatment of Infantile Spasms After Presumed Perinatal Stroke
CONCLUSION: This case suggests high-dose prednisolone could be considered for first-line therapy for children with infantile spasms due to perinatal stroke; further study is needed.
Source: Journal of Neuroscience Nursing - March 11, 2021 Category: Neuroscience Tags: Case Study Source Type: research

Progression of Large Vessel Disease in Patients With Giant Cell Arteritis–Associated Ischemic Stroke: The Role of Vascular Imaging: A Case Series
Conclusions Vascular imaging, especially with color-coded duplex sonography, could play a role in the follow-up of patients with GCA-related IS and identify those patients with higher risk of recurrent stroke.
Source: JCR: Journal of Clinical Rheumatology - December 1, 2021 Category: Rheumatology Tags: Original Articles Source Type: research

A Medication Combination for the Treatment of Central Post-Stroke Pain (CPSP) via the Adjuvant use of Prednisone with Gabapentin: A Case Report
Publication date: Available online 25 September 2015 Source:PM&R Author(s): Luis Batlle, Ryan Mattie, Robert Irwin Case Description CPSP is a neuropathic pain syndrome that can occur from pathology of the brain. The case presented is of a female with multiple comorbidities and who was found to have an acute infarct in the left middle and anterior cerebral artery territories. She began to complain of worsening diffuse right upper and lower extremity pain, and central post-stroke pain was diagnosed. First-line agents were contraindicated due to medical comorbidities, and chronic kidney disease only permitted the...
Source: PMandR - September 26, 2015 Category: Rehabilitation Source Type: research

Recognition of giant cell arteritis in patients with polymyalgia rheumatica who have a stroke: a cautionary tale
Abstract An 82‐year‐old woman with polymyalgia rheumatica (PMR) on prednisone 7 mg daily was admitted to an acute stroke unit with a right homonymous hemianopia, a left posterior cerebral artery occlusion and occipital lobe infarct. She had raised inflammatory markers, did not have a temporal artery biopsy, and was discharged on the same dose of prednisone. After 21 months, off prednisone, her ophthalmologist, concerned about giant cell arteritis (GCA), restarted prednisone 40 mg daily, with rapid, profound visual improvement. After 3 days her general practitioner, noting normal baseline inflammatory markers, stopp...
Source: Internal Medicine Journal - October 9, 2017 Category: Internal Medicine Authors: Donald H. Gutteridge, Frank L. Mastaglia Tags: Brief Communication Source Type: research

Ischemic stroke as a presenting feature of Wegener's granulomatosis.
We describe a 51-old-male who presented with complaints of slurred speech and left-sided weakness, along with bilateral pulmonary nodules on initial chest x-ray, which were associated with pulmonary symptoms in the past. A repeated computed tomography (CT) scan showed ischemia in the distribution of the right-middle cerebral artery. An open lung biopsy showed vasculitis with necrosis of a vessel wall, with a multinucleated giant cell, confirming the diagnosis of WG. The patient was successfully treated with cyclophosphamide and oral prednisone and he has continued in remission for one year. PMID: 24266130 [PubMed - in process]
Source: Connecticut Medicine - October 1, 2013 Category: Journals (General) Authors: Jethava A, Ali S Tags: Conn Med Source Type: research

A Medication Combination for the Treatment of Central Post-Stroke Pain (CPSP) via the Adjuvant use of Prednisone with Gabapentin: A Case Report
CPSP is a neuropathic pain syndrome that can occur from pathology of the brain. The case presented is of a female with multiple comorbidities and who was found to have an acute infarct in the left middle and anterior cerebral artery territories. She began to complain of worsening diffuse right upper and lower extremity pain, and central post-stroke pain was diagnosed. First-line agents were contraindicated due to medical comorbidities, and chronic kidney disease only permitted the use of low dose gabapentin.
Source: PM and R - September 23, 2015 Category: Rehabilitation Authors: Luis Batlle, Ryan Mattie, Robert Irwin Source Type: research

Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Internal Carotid Artery Floating Thrombus in Relapsing Polychondritis
We present a 52‐year‐old man without any known risk factors for stroke, treated with prednisone and azathioprine for relapsing polychondritis, who presented a minor left hemisphere stroke. Ultrasound of the neck vessels revealed an isoechogenic thrombus in the left internal carotid artery superimposed on a smooth moderately stenosing isoechogenic atheroma of the carotid bulb. The patient was treated with high‐dose tinzaparin and was followed with serial ultrasound. After 16 days, the thrombus demonstrated a hypoechogenic core surrounded by a hyperechogenic rim and the following day it resolved completely. Thrombus fo...
Source: Journal of Neuroimaging - February 23, 2014 Category: Radiology Authors: Theodoros Karapanayiotides, Konstantinos Kouskouras, Panagiotis Ioannidis, Eleni Polychroniadou, Nikolaos Grigoriadis, Dimitrios Karacostas Tags: Case Report Source Type: research

Primary Central Nervous System Vasculitis Triggered by Cytomegalovirus Encephalitis (P01.231)
CONCLUSIONS: Our case is the first reported case in the literature of proven CMV encephalitis triggering a subsequent non-infectious CNS vasculitis probably secondary to an autoimmune response. The absence of findings in the initial MRIs of the brain in spite of an intermittently symptomatic patient and the subsequent development of ischemic infarcts supports the theory of intermittent focal hypoperfusion, finally leading to infarction. The high clinical suspicion even with lack of clear evidence of the disease process and empirical treatment led to a successful clinical recovery.Disclosure: Dr. Rosales has nothing to disc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rosales, D., Garcia-Gracia, C., Salgado, E., Salanga, V. Tags: P01 Cerebrovascular Disease I Source Type: research

Fluctuating Mental Status and Fever of Unknown Origin (P1.030)
Conclusion: Central nervous system involvement as the initial manifestation of microscopic polyangiitis is rare and can result in a challenging clinical picture including recurrent ischemic strokes.Disclosure: Dr. Daniel has nothing to disclose. Dr. Brink has nothing to disclose. Dr. Hosley has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Daniel, A., Brink, J., Hosley, C. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Childhood-onset systemic polyarteritis nodosa and systemic lupus erythematosus: an overlap syndrome?
In conclusion, we described herein a possible overlap syndrome of two autoimmune diseases, where childhood-onset systemic polyarteritis nodosa occurred five years before the childhood-onset systemic lupus erythematosus diagnosis.
Source: Revista Brasileira de Reumatologia - July 13, 2015 Category: Rheumatology Source Type: research

Recurrent Spells of Unresponsiveness Secondary to Bilateral Carotid Stenosis Caused by Giant Cell Arteritis (P4.373)
Conclusions: The presence of bilateral carotid stenosis in patients with GCA is strongly associated with future risk of neurologic deficits. A vertebrobasilar steal syndrome may be a manifestation of bilateral, severe carotid stenosis. It may be difficult to separate atherosclerotic lesions from vasculitic lesions related to GCA, however, the presence of localized focal stenosis with relatively healthy arteries above and below the lesions may point to a vasculitic process. Rigorous attention should be given to modification of atherosclerotic risk factors as well as recognizing and treating the rare manifestation of GCA.Dis...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Wahba, M. Tags: Cerebrovascular Case Reports Source Type: research

An Unusual Complication of Pipeline Stenting (P3.296)
Conclusions:This case demonstrates a rare complication of pipeline stenting in that material can embolize leading to focal neurologic deficits that mimic stroke. The consensus on treatment is not established, but through multidisciplinary approach we have treated with immunosuppressant therapy with serial imaging and close outpatient neurology follow up.Disclosure: Dr. Stack has nothing to disclose. Dr. Cole has nothing to disclose. Dr. Cronin has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Kittner has nothing to disclose. Dr. Gandhi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Stack, C., Cole, J., Cronin, C., Shah, J., Kittner, S., Gandhi, D. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Efficacy and Safety of Pomalidomide in Combination with Prednisone in Patients with Myelofibrosis and Anemia -- Final Results of a Prospective Phase 2 Study
CONCLUSION:Pomalidomide with prednisone is safe therapy with good anti-anemia activity in patients with MF. It could lead to transfusion independence in one third of patients for a median duration of about 30 months. ClinicalTrials.gov Identifier: NCT00946270.Table 1.DisclosuresDaver: Alexion: Consultancy; ImmunoGen: Consultancy; Pfizer: Research Funding; Karyopharm: Research Funding; Otsuka: Consultancy; Novartis: Consultancy; ARIAD: Research Funding; Incyte: Consultancy; Pfizer: Consultancy; BMS: Research Funding; Sunesis: Research Funding; Daiichi-Sankyo: Research Funding; Sunesis: Consultancy; Kiromic: Research Funding...
Source: Blood - November 21, 2018 Category: Hematology Authors: Masarova, L., Daver, N. G., Kadia, T. M., Pemmaraju, N., Jabbour, E. J., Zhou, L., Pierce, S. A., Cortes, J. E., Kantarjian, H. M., Verstovsek, S. Tags: 634. Myeloproliferative Syndromes: Clinical: Poster I Source Type: research

Strategies for treatment of childhood primary angiitis of the central nervous system
Conclusion No grade-A evidence exists; however, this review provides recommendations for treatment of cPACNS.
Source: Neurology Neuroimmunology and Neuroinflammation - May 2, 2019 Category: Neurology Authors: Beelen, J., Benseler, S. M., Dropol, A., Ghali, B., Twilt, M. Tags: Autoimmune diseases, Vasculitis, All Pediatric, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke Views [amp ] Reviews Source Type: research