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Drug: Beta-Blockers

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Total 270 results found since Jan 2013.

Calcium channel blockers versus other classes of drugs for hypertension
CONCLUSIONS: For the treatment of hypertension, there is moderate certainty evidence that diuretics reduce major cardiovascular events and congestive heart failure more than CCBs. There is low to moderate certainty evidence that CCBs probably reduce major cardiovascular events more than beta-blockers. There is low to moderate certainty evidence that CCBs reduced stroke when compared to angiotensin-converting enzyme (ACE) inhibitors and reduced myocardial infarction when compared to angiotensin receptor blockers (ARBs), but increased congestive heart failure when compared to ACE inhibitors and ARBs. Many of the differences ...
Source: Cochrane Database of Systematic Reviews - October 17, 2021 Category: General Medicine Authors: Jiaying Zhu Ning Chen Muke Zhou Jian Guo Cairong Zhu Jie Zhou Mengmeng Ma Li He Source Type: research

Comparing pharmacotherapy in MINOCA versus medically managed obstructive acute coronary syndrome
This study uniquely compares the management and outcomes of MINOCA patients with a medically managed obstructive ACS (M-ACS) population. We retrospectively analysed registry data for consecutive patients admitted to the Gold Coast University Hospital with ACS requiring coronary angiography and identified patients with MINOCA and M-ACS. Baseline characteristics, pharmacological therapy and in-hospital outcomes were compared. In hospital outcomes were composite NACE, heart failure, stroke and major bleeding. Multivariate regression analysis was also performed to identify independent predictors of MINOCA. Multivariate regress...
Source: Heart and Vessels - October 10, 2021 Category: Cardiology Source Type: research

Effect of Amlodipine in Stroke and Myocardial infarction: A Systematic Review and Meta-analysis
ConclusionIn the pooled analysis of data from 12 randomised controlled trials and one double-blinded cohort study measuring the effect of CCBs, we found that the CCB amlodipine reduced the risk of stroke and MI in hypertensive patients. Superior results for amlodipine were found in ten of the 13 studies included in this meta-analysis.
Source: Cardiology and Therapy - September 4, 2021 Category: Cardiology Source Type: research

Long-term Use of Preoperative Beta-Blockers Is Associated With Reduced Postoperative Stroke After Thoracic Endovascular Aneurysm Repair
Thoracic endovascular aortic repair (TEVAR) has been established as the treatment of choice for a range of thoracic aortic pathologies. Beta-blockers represent a possible perioperative treatment option to improve TEVAR outcomes due to their role in management of aortic aneurysm, dissection, and Marfan syndrome. We investigated the effect of preoperative beta-blocker usage on outcomes of TEVAR using the Vascular Quality Initiative database.
Source: Journal of Vascular Surgery - August 24, 2021 Category: Surgery Authors: Kevin S. Yei, Niloofar Radgoudarzi, Rami Alhakim, Jonathan Unkart, Mahmoud B. Malas Tags: IP: Interactive Poster Session Source Type: research

Comparative effectiveness of metoprolol, ivabradine, and its combination in the management of inappropriate sinus tachycardia in coronary artery bypass graft patients
CONCLUSION: Ivabradine stands as a pharmacological option for controlling HR and rhythm without associated side effects in postoperative CABG patients with IST.
Source: Indian Journal of Pharmacology - August 18, 2021 Category: Drugs & Pharmacology Authors: Parloop Bhatt Niren Bhavsar Dhaval Naik Dhiren Shah Source Type: research

Cancers, Vol. 13, Pages 4012: Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention, and Anticoagulation Management
rdinale Atrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents a relevant complication of surgery, bearing considerable prognostic consequences. Different methods have therefore been explored to predict the occurrence of postoperative atrial fibrillation (POAF) and prevent it. In particular, the age among clinical factors, and N-terminal prohormone of brain natriuretic peptide ...
Source: Cancers - August 9, 2021 Category: Cancer & Oncology Authors: Gennaro Semeraro Carlo Meroni Carlo Cipolla Daniela Cardinale Tags: Review Source Type: research

Cancers, Vol. 13, Pages 4012: Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management
rdinale Atrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents a relevant complication of surgery, bearing considerable prognostic consequences. Different methods have therefore been explored to predict the occurrence of postoperative atrial fibrillation (POAF) and prevent it. In particular, the age among clinical factors, and N-terminal prohormone of brain natriuretic peptide ...
Source: Cancers - August 9, 2021 Category: Cancer & Oncology Authors: Gennaro Carmine Semeraro Carlo Ambrogio Meroni Carlo Maria Cipolla Daniela Maria Cardinale Tags: Review Source Type: research

Determinants of atrial fibrillation after cardiac surgery
Rev Cardiovasc Med. 2021 Jun 30;22(2):329-341. doi: 10.31083/j.rcm2202040.ABSTRACTPost-operative Atrial fibrillation (POAF) is a common complication post cardiac surgery. It can result in detrimental short- and long-term outcomes due to the increased risk of stroke, cardiac arrest and congestive heart failure in addition to prolonged intensive care and total hospital stay raising the overall healthcare cost. Accurately identifying predictors and biomarkers for POAF ensures that patients at greatest risk can be given the appropriate prophylactic measures; resources can be distributed to the groups who are most in need and w...
Source: Reviews in Cardiovascular Medicine - July 14, 2021 Category: Cardiology Authors: Mashal Qureshi Ammaarah Ahmed Victoria Massie Ellenor Marshall Amer Harky Source Type: research

Determining Safe Participation in Aerobic Exercise Early After Stroke Through a Graded Submaximal Exercise Test.
CONCLUSION: A graded submaximal exercise test without ECG but with symptom monitoring and conservative heart rate and perceived exertion endpoints may facilitate safe exercise intensities early after stroke. Symptom-limited exercise testing with ECG is still recommended when progressing to higher-intensity exercise. IMPACT: Concerns about cardiovascular risk are a barrier to physical therapists implementing aerobic exercise in stroke rehabilitation. This study showed that, in the absence of access to exercise testing with ECG, submaximal testing with conservative heart rate and perceived exertion endpoints and symptom...
Source: Physical Therapy - June 2, 2020 Category: Physiotherapy Authors: Inness E, Aqui A, Foster E, Fraser J, Danells CJ, Biasin L, Brunton K, Howe JA, Poon V, Tang A, Mansfield A, Marzolini S, Oh P, Bayley M Tags: Phys Ther Source Type: research

Contrast-Induced Acute Kidney Injury in Radiologic Management of Acute Ischemic Stroke in the Emergency Setting INTERVENTIONAL
CONCLUSIONS: Patients with low baseline renal function had the highest incidence of postcontrast acute kidney injury after CTA and cerebral angiography, but no fatal adverse effects were documented. Thus, patients suspected of having a stroke should be actively managed with respect to neurovascular function.
Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Myung, J. W., Kim, J. H., Cho, J., Park, I., Kim, H. Y., Beom, J. H. Tags: INTERVENTIONAL Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Medication-taking Behaviors and Perceptions Among Adults with Heart Failure (From the REasons for Geographic And Racial Differences in Stroke REGARDS Study)
We examined medication-taking behaviors and perceptions among individuals with HF with a particular focus on BBs. A mailed survey on medication use was administered to US adults with HF enrolled in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Source: The American Journal of Cardiology - February 23, 2019 Category: Cardiology Authors: Matthew T. Mefford, Alysse Sephel, Melissa K. Van Dyke, Ligong Chen, Raegan W. Durant, Todd M. Brown, Matthew Fifolt, Juan Maya, Parag Goyal, Monika M. Safford, Emily B. Levitan Source Type: research

Major side effects from popular medicines: Beta-blockers and painkillers found to double risk of stroke
(Natural News) Every two seconds, someone somewhere is having a stroke, and the cause isn’t always what you’re told. A stroke is when the blood supply to part of your brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients. Most strokes (80 percent) that occur are ischemic strokes, where the arteries leading to...
Source: NaturalNews.com - March 8, 2018 Category: Consumer Health News Source Type: news

Does Prior Use of Beta Blockers Affect Functional Outcomes Post Ischemic Stroke Endovascular Intervention? (P5.296)
Conclusions:Prior use of beta blockers did not lead to better functional outcomes (MRS ≤2) in acute ischemic stroke patients undergoing EVI. Findings should be further confirmed in larger population.Disclosure: Dr. Albadareen has nothing to disclose. Dr. Gronseth has received personal compensation in an editorial capacity for Neurology. Dr. Gronseth has received research support from the American Academy of Neurology. Dr. Mittal has nothing to disclose. Dr. Sharrock has nothing to disclose. Dr. Keshary has nothing to disclose. Dr. Abraham has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Albadareen, R., Gronseth, G., Mittal, M., Sharrock, M., Keshary, S., Abraham, M. Tags: Stroke Recovery and Rehabilitation Source Type: research

Prestroke treatment with beta-blockers for hypertension is not associated with severity and poor outcome in patients with ischemic stroke: data from a national stroke registry
Background: Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypertensive patients hospitalized with acute ischemic stroke. Methods: All 3915 patients with ischemic stroke, treated prestroke for hypertension and registered in the National Acute Stroke ISraeli, were included. Treatment for hypertension was classified by medication type (beta-blockers, diuretics, calcium ant...
Source: Journal of Hypertension - March 2, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research

Pre-Stroke Use of Beta-Blockers Does Not Lower Post-Stroke Infection Rate: An Exploratory Analysis of the Preventive Antibiotics in Stroke Study
This study is aimed at investigating the association between BB treatment at baseline and post-stroke infection in the Preventive Antibiotics in Stroke Study (PASS), a prospective clinical trial.Methods: We performed an exploratory analysis in PASS, 2,538 patients with acute phase of stroke (24 h after onset) were randomized to ceftriaxone (intravenous, 2 g per day for 4 days) in addition to stroke unit care, or standard stroke unit care without preventive antibiotic treatment. All clinical data, including use of BBs, was prospectively collected. Infection was diagnosed by the treating physician, and independently by an ex...
Source: Cerebrovascular Diseases - October 4, 2016 Category: Neurology Source Type: research

Beta-blockers are associated with decreased in-hospital mortality and stroke in acute decompensated heart failure: Findings from a retrospective analysis of a 22-year registry in the Middle East (1991-2013).
CONCLUSIONS: Previous beta-blockade therapy in patients presenting with ADHF decreases intra-hospital mortality and the incidence of CV events and transient ischemic attacks. Moreover, non-withdrawal of beta-blockers during hospitalization has a favorable outcome. PMID: 27550053 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - August 21, 2016 Category: Drugs & Pharmacology Authors: Khalil CA, Al Suwaidi J, Singh R, Asaad N, Abushahba G, Kunju U, Al-Qahtani A, AlBinali HA Tags: Curr Vasc Pharmacol Source Type: research

Get Rid of Toxins to Reduce Risk of Stroke
Effects of Toxins I’ve been warning you about the toxins in our environment for years. They cause inflammation… They make you gain weight… They cause you to feel fatigued… Our exposure to them starts before we’re even born. One study found 287 chemicals and toxins in the blood of newborn babies.1 It’s shocking. What is in the air we breathe? We breathe in toxins and air pollutants every day. Carbon dioxide, lead, nitrogen oxide, sulfur dioxide, and particulate matter (PM). Causes of Stroke Now, a new study reveals that air pollution is responsible for as many as one-third of all strokes.2 That’...
Source: Al Sears, MD Natural Remedies - July 15, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

From preoperative evaluation to stroke center: Management of postoperative acute ischemic stroke
This article reviews the perioperative management (covering diagnosis and treatment), prevention (covering surgery postponement, management with anticoagulant/antiplatelet and the growing interest in statins and beta-blockers) and intraoperative recommendations (covering anaesthetic techniques, ventilation strategies, transfusion and blood pressure management) specifically for the general surgical population. A summary of current treatments is enlightened by recently described evidence for the effectiveness of mechanical thrombectomy.
Source: Anaesthesia, Critical Care and Pain Medicine - May 31, 2016 Category: Anesthesiology Source Type: research

Preoperative treatment with {beta}-blockers is associated with elevated postoperative mortality and cardiac morbidity in patients with uncomplicated hypertension undergoing non-cardiac surgery
Commentary on: Jørgensen ME, Hlatky MA, Køber L, et al.. β-Blocker-associated risks in patients with uncomplicated hypertension undergoing noncardiac surgery. JAMA Intern Med 2015;175:1923–31. Context The role of β-blockers in preventing cardiovascular complications of non-cardiac surgery is controversial. Early enthusiasm was dampened by accumulating trial data and concerns about the scientific validity of several trials. When studies with uncertain validity are excluded, meta-analyses of randomised trials show that perioperative β-blockers (started within 1 day before surgery) prev...
Source: Evidence-Based Medicine - May 22, 2016 Category: Internal Medicine Authors: Wijeysundera, D. N. Tags: Liver disease, Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Chemotherapy, Ischaemic heart disease Aetiology/Harm Source Type: research

Antihypertensive Drug Use, Blood Pressure Variability, and Incident Stroke Risk in Older Adults: Three-City Cohort Study Clinical Sciences
Conclusions— The angiotensin receptor blocker and β-blocker drug classes were associated with incident stroke and ischemic stroke in older adults. BPV was generally not associated with incident stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Tully, P. J., Debette, S., Dartigues, J.-F., Helmer, C., Artero, S., Tzourio, C. Tags: High Blood Pressure, Hypertension, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Beta-blockers are not associated with stroke severity and outcome in hypertensive patients: data from a national stroke registry
Lowering blood pressure (BP) with beta-blockers is less effective in reducing the risk of stroke than with other agents. However, studies on associations between use of beta-blockers and stroke severity are inconclusive. We assessed the association between pre-stroke use of beta-blockers and stroke severity, disability and death in a large prospective national registry of hospitalized hypertensive patients with acute stroke.
Source: Journal of the American Society of Hypertension - March 31, 2016 Category: Cardiology Authors: Ehud Grossman, David Tanne, Silvia Koton Tags: Stroke Source Type: research

To Have (Or Maybe Not Have) a Stroke
"You're not leaving here with your blood pressure that high," the doctor said. It was 189 over something equally ridiculous. It was not interested in coming down. Finally she said, "Okay, pick up this prescription on your way out and take it the minute you get home." Vividly running through my head were images of my mother, who suffered a series of strokes that eventually killed her in her 70th year. Plus images of assorted aunts and others who suffered debilitating strokes and often early deaths. "But . . . but," I said to the doctor, as I have repeatedly said since my carefree youth; "I don't have high blood pressure. My...
Source: Healthy Living - The Huffington Post - February 10, 2016 Category: Consumer Health News Source Type: news

Fitness and cognition in the elderly: The Austrian Stroke Prevention Study
Conclusions: Higher Vo2max is associated with better global cognitive function and with better performance in the cognitive domains of memory, executive function, and motor skills in the middle-aged and elderly. The association is not mediated by the presence of white matter lesions, lacunes, and brain atrophy.
Source: Neurology - February 1, 2016 Category: Neurology Authors: Freudenberger, P., Petrovic, K., Sen, A., Toglhofer, A. M., Fixa, A., Hofer, E., Perl, S., Zweiker, R., Seshadri, S., Schmidt, R., Schmidt, H. Tags: MRI, All Cerebrovascular disease/Stroke, Cognitive aging, Cohort studies ARTICLE Source Type: research

Beta-blocker use is associated with lower stroke and death after carotid artery stenting
The objective of this study was to assess the effect of preoperative medications, procedure parameters, and patient characteristics on outcomes of CAS performed in a multispecialty national database.
Source: Journal of Vascular Surgery - October 30, 2015 Category: Surgery Authors: Tammam Obeid, Isibor Arhuidese, Alicia Gaidry, Umair Qazi, Christopher Abularrage, Philip Goodney, Jack Cronenwett, Mahmoud Malas Tags: Clinical Paper Source Type: research

{beta}-Blockers, Pneumonia, and Outcome After Ischemic Stroke: Evidence From Virtual International Stroke Trials Archive Clinical Sciences
Conclusions— In this large nonrandomized comparison, on-stroke BB was associated with reduced mortality. Prestroke and on-stroke BB were inversely associated with incidence of nosocomial pneumonia. Randomized trials investigating the potential of β-blockade in acute stroke may be warranted.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Sykora, M., Siarnik, P., Diedler, J., for the VISTA Acute Collaborators, VISTA Acute Collaborators, Lees, Alexandrov, Bath, Bluhmki, Bornstein, Claesson, Davis, Donnan, Diener, Fisher, Ginsberg, Gregson, Grotta, Hacke, Hennerici, Hommel, Kaste, Lyden, Mar Tags: Acute Cerebral Infarction, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Interventions for deliberately altering blood pressure in acute stroke.
CONCLUSIONS: There is insufficient evidence that lowering blood pressure during the acute phase of stroke improves functional outcome. It is reasonable to withhold blood pressure-lowering drugs until patients are medically and neurologically stable, and have suitable oral or enteral access, after which drugs can than be reintroduced. In people with acute stroke, CCBs, ACEI, ARA, beta blockers and NO donors each lower blood pressure while phenylephrine probably increases blood pressure. Further trials are needed to identify which people are most likely to benefit from early treatment, in particular whether treatment started...
Source: Cochrane Database of Systematic Reviews - October 28, 2014 Category: Journals (General) Authors: Bath PM, Krishnan K Tags: Cochrane Database Syst Rev Source Type: research

Beta-blockers for preventing stroke recurrence.
CONCLUSIONS: To date, no available evidence supports the routine use of beta-blockers for secondary prevention after stroke or TIA. More studies with larger samples are needed. PMID: 25317988 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 15, 2014 Category: Journals (General) Authors: De Lima LG, Saconato H, Atallah AN, da Silva EM Tags: Cochrane Database Syst Rev Source Type: research