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The Informal International Network Getting Disabled Ukrainians Out of the War Zone
When Tanya Herasymova woke up on February 24 to the news that Russia had invaded Ukraine, her first thought was to get underground. If the Russian army began bombing her city Kamianske, close to the separatist region Donetsk, she would be at greater risk in her 4th floor apartment. But there was a problem: none of the city’s bomb shelters were accessible to wheelchair users, leaving Herasymova with nowhere to take cover. “It was a horrible feeling because I knew that I couldn’t go down there by myself. I can’t be alone, I need someone to help me,” Herasymova says. “I realized that the on...
Source: TIME: Health - March 31, 2022 Category: Consumer Health News Authors: Eloise Barry Tags: Uncategorized Londontime Ukraine Source Type: news

Access to stroke care in Europe: results of a vignette approach
ConclusionsWhile stroke related services are formally covered in almost all countries, considerable access problems exist in several countries. Future cross-country surveys of access to stroke care should collect quantitative data related to proportions of patients receiving particular services as well as qualitative data on access barriers.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research

Predictors of outcome events and 6-year mortality after carotid endarterectomy and carotid stenting in patients with carotid artery stenosis.
CONCLUSIONS: The results of our study show that long-term mortality does not differ between CEA and CAS. PMID: 33242214 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - November 26, 2020 Category: Neurology Authors: Leško N, Maretta M, Škorvánek M, Frankovičová M, Sihotský V, Špak Ľ, Gdovinová Z Tags: Neurol Neurochir Pol Source Type: research

MicroRNA-19a mediates neuroprotection through the PTEN/AKT pathway in SK-N-SH cells after oxygen-glucose deprivation/reoxygenation injury.
Abstract Ischemic stroke is one of the most common public health problems worldwide. The aim of the present study was to investigate the role of miR-19a and its possible target genes in SK-N-SH cells subjected to oxygen-glucose deprivation/re-oxygenation (OGD/R) injury. SK-N-SH cells are a suitable model for host transfection. SK-N-SH cells were transfected with miR-19a mimic or inhibitor and PTEN-small interfering (si) RNA in order to alter the expression of miR-19a, PTEN and AKT. The expression changes in acute cerebral ischemic injury (ACII) were verified using RT-qPCR and Western blotting. Expression changes a...
Source: General Physiology and Biophysics - April 30, 2020 Category: Physiology Authors: Jin X, Wang H, Yin S, Zhang Y Tags: Gen Physiol Biophys Source Type: research

Patient-Associated Characteristics Influencing the Risk for Non-Persistence with Statins in Older Patients with Peripheral Arterial Disease
ConclusionsPatients identified as high risk for non-persistence require special attention aimed at the improvement of their persistence with statin treatment.
Source: Drugs and Aging - June 28, 2019 Category: Geriatrics Source Type: research

EQ-5D studies in nervous system diseases in eight Central and East European countries: a systematic literature review
ConclusionsEQ-5D research activity in neurology has been increasing through the years in studied CEE countries. There are clinical areas with the significant social burden, such as a migraine or meningitis, that are completely lacking data, other areas, such as stroke or epilepsy, with very scarce data.
Source: The European Journal of Health Economics - May 15, 2019 Category: Health Management Source Type: research

A Kinematic Study of Progressive Micrographia in Parkinson's Disease
This study has investigated the kinematic features of progressive micrographia during a repetitive writing task. Twenty-four PD patients with duration since diagnosis of <10 years and 24 age-matched controls wrote the letter “e” repeatedly. PD patients were studied in defined off states, with scoring of motor function on the Unified Parkinson's Disease Rating Scale Part III. A digital tablet captured x-y coordinates and ink-pen pressure. Customized software recorded the data and offline analysis derived the kinematic features of pen-tip movement. The average size of the first and the last fi...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Publication date: 10–16 November 2018Source: The Lancet, Volume 392, Issue 10159Author(s): Hmwe Hmwe Kyu, Degu Abate, Kalkidan Hassen Abate, Solomon M Abay, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Molla Abebe, Zegeye Abebe, Olifan Zewdie Abil, Victor Aboyans, Aklilu Roba Abrham, Laith Jamal Abu-Raddad, Niveen M E Abu-Rmeileh, Manfred Mario Kokou AccrombessiSummaryBackgroundHow long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading caus...
Source: The Lancet - November 11, 2018 Category: General Medicine Source Type: research

Patient ‐related characteristics associated with non‐persistence with statin therapy in elderly patients following an ischemic stroke
ConclusionsOur findings suggest that patients aged ≥75 years or those with the presence of diabetes mellitus, dementia, hypercholesterolemia or polypharmacy were likely to be persistent with statin therapy, whereas those with anxiety disorders may need greater assistance with persistence of statin therapy. Copyright © 2016 John Wiley & Sons, Ltd.
Source: Pharmacoepidemiology and Drug Safety - November 30, 2016 Category: Drugs & Pharmacology Authors: Martin Wawruch, Dusan Zatko, Gejza Wimmer, Jan Luha, Vasil Hricak, Jan Murin, Peter Kukumberg, Tomas Tesar, Adam Hloska, Rashmi Shah Tags: Original Report Source Type: research

Universal and language-specific sublexical cues in speech perception: a novel electroencephalography-lesion approach
See Cappa (doi:10.1093/brain/aww090) for a scientific commentary on this article.   The phonological structure of speech supports the highly automatic mapping of sound to meaning. While it is uncontroversial that phonotactic knowledge acts upon lexical access, it is unclear at what stage these combinatorial rules, governing phonological well-formedness in a given language, shape speech comprehension. Moreover few studies have investigated the neuronal network affording this important step in speech comprehension. Therefore we asked 70 participants—half of whom suffered from a chronic left hemispheric lesion&mdas...
Source: Brain - May 26, 2016 Category: Neurology Authors: Obrig, H., Mentzel, J., Rossi, S. Tags: CNS Injury and Stroke Original Articles Source Type: research

Factors Influencing Non-Persistence with Antiplatelet Medications in Elderly Patients After Ischaemic Stroke
Conclusions Our results suggest that women, patients aged <75 years, and patients without certain comorbid conditions may need improved assistance in secondary prevention management after an ischaemic stroke.
Source: Drugs and Aging - March 28, 2016 Category: Geriatrics Source Type: research

The future burden of obesity-related diseases in the 53 WHO European-Region countries and the impact of effective interventions: a modelling study
Conclusions Modelling future disease trends is a useful tool for policymakers so that they can allocate resources effectively and implement policies to prevent NCDs. Future research will allow real policy interventions to be tested; however, better surveillance data on NCDs and their risk factors are essential for research and policy.
Source: BMJ Open - July 25, 2014 Category: Journals (General) Authors: Webber, L., Divajeva, D., Marsh, T., McPherson, K., Brown, M., Galea, G., Breda, J. Tags: Open access, Epidemiology, Global health, Nutrition and metabolism, Public health, Research methods Source Type: research