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Total 19 results found since Jan 2013.

Should beetles be named after Adolf Hitler?
In 1934, a German paleontologist named a giant flying insect from the Carboniferous period Rochlingia hitleri , after Adolf Hitler, who had just taken power in Germany, and Hermann Röchling, an anti-semitic steel manufacturer and member of the Nazi Party. Three years later, an Austrian amateur entomologist named a brown, eyeless beetle from Slovenian caves Anophthalmus hitleri because he admired Hitler. In recent years, neo-Nazis have reportedly paid thousands for specimens, pushing the beetle toward extinction . Some researchers have argued for years that A. hitleri and other spec...
Source: Science of Aging Knowledge Environment - September 5, 2023 Category: Geriatrics Source Type: research

Did interstellar debris fall to the sea floor? Claim meets sea of doubt
In 2014, a rock from space blazed through the atmosphere and exploded off the coast of Papua New Guinea with such ferociousness that some researchers believe the object came from beyond the Solar System. Now, a team of researchers says it has recovered remnants of the meteor from the floor of the Pacific Ocean and claims that a preliminary analysis of their unusual composition points to an origin around another star. Only in the past few years have astronomers realized that interstellar objects sometimes whizz through the Solar System and might even hit Earth. Finding a lump of rock from another planetary system would...
Source: Science of Aging Knowledge Environment - August 30, 2023 Category: Geriatrics Source Type: research

Predictors of stroke favorable functional outcome in guinea, results from the conakry stroke registry
Stroke epidemiology and health care systems are different in Low to middle income countries (LMIC) than in high income countries (HIC) failing HIC based predictive model.    We aimed at identifying the impact of modifiable variables in acute stroke management in Conakry, Guinea as potential predictors of favorable stroke outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Cisse Abass Fode, Ligot No émie, Conde Kaba, Barry Souleymane Djigué, Toure Mohamed Lamine, Konate Mamadi, Soumah Fode Mohamed, Diawara Karinka, Traore Mohamed, Naeije Gilles Source Type: research

Hypertension is associated with increased mortality in patients with tuberculosis in Guinea-Bissau
Tuberculosis (TB) continues to be a major health problem in low- and middle-income countries (LMICs). In 2019, WHO estimated that there were 10 million new cases of TB, and 1.4 million deaths due to TB worldwide (World Health Organization, 2020). At the same time, LMICs face a rapid increase in the burden of noncommunicable diseases such as diabetes mellitus (DM) and cardiovascular diseases (CVD), including coronary heart disease and stroke. More than 75% of cardiovascular deaths occur in LMICs (World Health Organization, 2014).
Source: International Journal of Infectious Diseases - July 2, 2021 Category: Infectious Diseases Authors: Anneline B Seegert, Cecilie B Patsche, Armando Sifna, Victor F Gomes, Christian Wejse, Merete Storgaard, Frauke Rudolf Source Type: research

IJERPH, Vol. 17, Pages 4237: Validation of the Spanish Version of Newcastle Stroke-Specific Quality of Life Measure (NEWSQOL)
Conclusion: The Spanish version of the NEWSQOL questionnaire is reliable, valid, and feasible to evaluate quality of life in the Spanish population.
Source: International Journal of Environmental Research and Public Health - June 13, 2020 Category: Environmental Health Authors: Concepci ón Soto-Vidal Soraya Pacheco-da-Costa Victoria Calvo-Fuente Sara Fern ández-Guinea Carlos Gonz ález-Alted Tom ás Gallego-Izquierdo Tags: Article Source Type: research

Overlooked Virus Killer
Sales of vitamin C supplements have tripled in the last few weeks… And the most powerful kind of vitamin C is sold out on Amazon. (More on that in a minute.) I’m glad to see people turning to vitamin C. But the the chewable form you usually find at the drugstore won’t give you the boost you’re looking for. You see, absorption — or bioavailability — is an issue, and your body can only absorb about 500 mg of this conventional form of vitamin C before you hit saturation. And that’s nowhere near enough. In a moment I’ll show you a better form of vitamin C… and how you can take ...
Source: Al Sears, MD Natural Remedies - May 6, 2020 Category: Complementary Medicine Authors: Dr.A.Sears Tags: Health Nutrition Source Type: news

Introduction to Purinergic Signaling.
Abstract Purinergic signaling was proposed in 1972, after it was demonstrated that adenosine 5'-triphosphate (ATP) was a transmitter in nonadrenergic, noncholinergic inhibitory nerves supplying the guinea-pig taenia coli. Later, ATP was identified as an excitatory cotransmitter in sympathetic and parasympathetic nerves, and it is now apparent that ATP acts as a cotransmitter in most, if not all, nerves in both the peripheral nervous system and central nervous system (CNS). ATP acts as a short-term signaling molecule in neurotransmission, neuromodulation, and neurosecretion. It also has potent, long-term (trophic) ...
Source: Mol Biol Cell - October 27, 2019 Category: Molecular Biology Authors: Burnstock G Tags: Methods Mol Biol Source Type: research

Minimal Setting Stroke Unit in a Sub-Saharan African Public Hospital
Introduction: Sub-Saharan Africa (SSA) has the highest stroke prevalence along with a case fatality that amounts to 40%. We aimed to assess the effect of a minimal setting stroke unit in SSA Public hospital on stroke mortality and main medical complications. Materials and Methods: The study was set in Conakry, Guinea, Ignace Deen public referral hospital. Clinical characteristics, hospital mortality and main medical stroke complications rates (pneumonia, urinary tract infections, sores and venous thromboembolism) of admitted stroke patients after the installation of a minimal stroke unit equipped with heart rate, bloo...
Source: Frontiers in Neurology - August 6, 2019 Category: Neurology Source Type: research

Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?
This study demonstrated unaltered vascular conductance in response to lumbar sympathetic stimulation in CIH-exposed rats. Aortic compliance was increased and estimated blood volume was unchanged in CIH-exposed rats. Increased blood pressure was related to an increase in cardiac output, which was confirmed by echocardiography (Lucking et al., 2014). It is suggested therefore that hypertension in the CIH model can be evoked by over-excitation of the cardiac arm of sympathetic nervous system (SNS), even before mechanisms of enhanced peripheral vasoconstriction and endothelial dysfunction are initiated (Naghshin et al., 2009)....
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Isolation of Antimicrobial Compounds From Cnestis ferruginea Vahl ex. DC (Connaraceae) Leaves Through Bioassay-Guided Fractionation
Conclusion In conclusion, aqueous extracts of C. ferruginea leaves showed antimicrobial activity due to the presence of hydroquinone and caffeic acid methyl ester. This supports its traditional use for infections and confirmed that the active molecules are water-soluble. Author Contributions KK, SP, LVP, and WL conceived and designed the experiments. SP, KK, M-RY, and J-GL performed the experiments. SP, LVP, WL, M-RY, J-GL, and Z-HJ analyzed the data. WL and Z-HJ contributed reagents, materials, and analysis tools. KK, SP, WL, M-RY, Z-HJ, and LVP contributed to the writing of the manuscript. All authors contributed to m...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research

Stroking GUINEA PIGS helps people recover from catastrophic brain injuries
A study by the University of Basel found allowing traumatic brain injury patients to stroke 'cute animals' during rehabilitation sessions nearly doubled how chatty and positive they were.
Source: the Mail online | Health - April 9, 2019 Category: Consumer Health News Source Type: news

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Prenatal hypoxia impairs cardiac mitochondrial and ventricular function in guinea pig offspring in a sex-related manner.
CONCLUSION: Prenatal HPX is a programming stimulus that increases MAP and decreases cardiac and mitochondrial function in male offspring. Sex-related differences in the contractile and mitochondrial responses suggest female GPs are protected against cardiovascular programming of prenatal HPX. PMID: 30365351 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 26, 2018 Category: Physiology Authors: Thompson LP, Chen L, Polster BM, Pinkas G, Song H Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research

Translation into Spanish and a preliminary analysis of the psychometric properties of the Newcastle Stroke-Specific Quality of Life Measure (NEWSQOL) questionnaire for rating the quality of life among post-stroke patients.
CONCLUSION: The Spanish version of the NEWSQOL questionnaire is reliable for evaluating the quality of life in post-stroke patients, as well as being well accepted. The questionnaire must be used in more broader samples in order to evaluate its validity and sensitivity. PMID: 29178105 [PubMed - in process]
Source: Revista de Neurologia - November 29, 2017 Category: Neurology Authors: Soto-Vidal C, Pacheco-da-Costa S, Fernandez-Guinea S, Gallego-Izquierdo T Tags: Rev Neurol Source Type: research

Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca(2+) Sensitivity.
Abstract Omecamtiv mecarbil (OM) is a pharmacological agent that augments cardiac contractile function by enhancing myofilament Ca(2+) sensitivity. Given that interventions that increase myofilament Ca(2+) sensitivity have the potential to alter length-dependent activation (LDA) of cardiac myofilaments, we tested the influence of OM on this fundamental property of the heart. This is significant not only because LDA is prominent in cardiac muscle but also because it contributes to the Frank-Starling law, a mechanism by which the heart increases stroke volume in response to an increase in venous return. We measured ...
Source: Biophysical Journal - August 22, 2017 Category: Physics Authors: Gollapudi SK, Reda SM, Chandra M Tags: Biophys J Source Type: research