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Total 20 results found since Jan 2013.

How to Keep Your Home Cool in Extreme Heat
Global temperatures have reached alarmingly high levels across the U.S., Europe, and Asia as heat waves set record highs this week. Parts of European countries including most of Italy, eastern Croatia, southern Spain, southern Bosnia and Herzegovina, and Montenegro are under red alert, the European Union’s Emergency Response Coordination Centre said on Wednesday. Meanwhile, as of July 18, Phoenix had experienced 19 consecutive days of 110°F temperatures or higher. And Beijing is also experiencing a record stretch of 95°F heat. The extreme heat comes as weather phenomenon El Niño, which occurs every tw...
Source: TIME: Health - July 19, 2023 Category: Consumer Health News Authors: Solcyre Burga Tags: Uncategorized climate change extreme weather healthscienceclimate Source Type: news

Air Pollution Kills Millions Every Year: Action Needed
The World Health Organization calls air pollution the “single biggest environmental threat to human health" and estimates that 99 percent of the world’s population live in locations that are above WHO thresholds designed to protect human health. . Credit: Malav Goswami/IPSBy Felix HorneSep 2 2022 (IPS) Tarik, age 42, lives in a village adjacent to a decades-old coal power plant in Bosnia and Herzegovina. On the day we visited, Bosnian cities were some of the most polluted places on Earth. Describing the devastating health toll the air pollution took each year on the village’s older residents he voiced his fear for hi...
Source: IPS Inter Press Service - Health - September 2, 2022 Category: International Medicine & Public Health Authors: Felix Horne Tags: Environment Global Headlines Health Source Type: news

The association between serine hydroxymethyl transferase 1 gene hypermethylation and ischemic stroke.
This study aimed to determine the correlation between serine hydroxymethyl transferase 1 (SHMT1) gene methylation and ischemic stroke. A total of 202 age- and sex-matched individuals were included. Quantitative methylation-specific polymerase chain reaction (qMSP-PCR) was used to analyze the DNA methylation level. The plasma homocysteine (Hcy) concentration was much higher in ischemic cases than in controls (p = 0.009), while the HDL levels in stroke cases were considerably lower than in controls (p = 0.005). A significantly higher level of SHMT1 methylation was observed in the ischemic strokes (58.82 ± 17.83 %) compared ...
Source: Bosnian Journal of Basic Medical Sciences - December 3, 2020 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

SARS-CoV-2 infection of the nervous system: A review of the literature on neurological involvement in novel coronavirus disease (COVID-19).
In conclusion, SARS-CoV-2 infection can cause multiple neurological syndromes in a more complex presentation. Therefore, this review elucidated the involvement of the nervous system in SARS-CoV-2 infection and will hopefully help improve the management of COVID-19. PMID: 32530389 [PubMed - as supplied by publisher]
Source: Bosnian Journal of Basic Medical Sciences - June 13, 2020 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

High MTHFR promoter methylation levels in men confer protection against ischemic stroke.
In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and the risk of IS, followed by the analysis of potential interactions between environmental factors and DNA methylation levels that affect IS risk. We recruited 164 patients with hypertension and IS (case group) and 345 age- and sex-matched patients with hypertension only (control group). Demographic and clinical information was obtained using questionnaires, and blood samples were collected for biochemical analyses. Fluorescence quantitative methylation-specific PCR (qMSP) was used to detect MTHFR promoter methyl...
Source: Bosnian Journal of Basic Medical Sciences - May 4, 2020 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

DNA methylation of AHCY may increase the risk of ischemic stroke.
This study aimed to determine the correlation between DNA methylation of the gene encoding S-adenosylhomocysteine hydrolase (AHCY) and the risk of ischemic stroke in 64 ischemic stroke patients and 138 patients with traumatic brain injury (control group). The methylation level of AHCY was analyzed using quantitative methylation-specific polymerase chain reaction. Statistically significant differences in AHCY methylation levels were observed between the case group [medians (interquartile range): 0.13% (0.09%, 0.27%)] and the control group [0.06% (0.00%, 0.17%), p < 0.0001], and these associations remained significant in ...
Source: Bosnian Journal of Basic Medical Sciences - February 7, 2020 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Publication date: 10–16 November 2018Source: The Lancet, Volume 392, Issue 10159Author(s): Hmwe Hmwe Kyu, Degu Abate, Kalkidan Hassen Abate, Solomon M Abay, Cristiana Abbafati, Nooshin Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Jemal Abdela, Ahmed Abdelalim, Ibrahim Abdollahpour, Rizwan Suliankatchi Abdulkader, Molla Abebe, Zegeye Abebe, Olifan Zewdie Abil, Victor Aboyans, Aklilu Roba Abrham, Laith Jamal Abu-Raddad, Niveen M E Abu-Rmeileh, Manfred Mario Kokou AccrombessiSummaryBackgroundHow long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading caus...
Source: The Lancet - November 11, 2018 Category: General Medicine Source Type: research

Cardiovascular Health Status and Metabolic Syndrome in Adults Living in a Transition European Country: Findings from a Population-Based Study
There are only a few published studies on the relationship between cardiovascular health (CVH) status as proposed by the American Heart Association and the metabolic syndrome (MetS) in persons with cardiovascular disease (CVD). The aim of this study was to assess the prevalence of CVH and MetS and their correlation in the adult population of the Republic of Srpska, Bosnia and Herzegovina, in order to evaluate which set of cardiovascular risk factors (low or medium CVH status and MetS), or the combination of both, is a better predictor for the occurrence of CVD.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2017 Category: Neurology Authors: Dragana Stojisavljevi ć, Janko Janković, Miloš Erić, Jelena Marinković, Slavenka Janković Source Type: research

Non-endoscopic minimally invasive evacuation of intracerebral haematoma (ICH): A case report.
Authors: Velnar T Abstract Spontaneous intracerebral haemorrhage (ICH) is one of the most serious causes of stroke, leading to high rates of disability and mortality. In addition to intensive medical treatment, surgery may help to improve the prognosis in patients with ICH. A rapid reversal of coagulopathy is essential in these patients, although it may be difficult to achieve in various bleeding disorders. In such cases, when surgery is needed, a minimally invasive approach is recommended. In this case report, we described and shortly discussed the evacuation of ICH with a minimally invasive non-endoscopic surgica...
Source: Bosnian Journal of Basic Medical Sciences - October 26, 2017 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

Safety of once- or twice-daily dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with nonvalvular atrial fibrillation: A NOAC-TR study.
In this study, we investigated the adherence to once- or twice-daily dosing of NOACs and the risk of bleeding in nonvalvular atrial fibrillation (NVAF) patients. This multicenter cross-sectional study, conducted between 1 September 2015 and 28 February 2016, included 2214 patients receiving NOACs for at least 3 months, due to NVAF. Patients receiving once-daily or twice-daily NOAC doses were 1:1 propensity score matched for baseline demographic characteristics and the presence of other diseases. The medication adherence was assessed by the 8-item Morisky Medication Adherence Scale. Risk factors were investigated in relatio...
Source: Bosnian Journal of Basic Medical Sciences - October 3, 2017 Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research

The Patterns of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Use in Patients with Atrial Fibrillation in Seven Balkan Countries: a Report from the BALKAN-AF Survey
ConclusionsNOACs are increasingly used in AF patients in the Balkan Region, but NOAC use is predominantly guided by factors other than evidence-based decision-making (e.g., drug availability on the market or reimbursement policy). Efforts are needed to establish an evidence-based approach to OAC selection and to facilitate the optimal use of OAC, thus improving the outcomes in AF patients in this large region.
Source: Advances in Therapy - August 9, 2017 Category: Drugs & Pharmacology Source Type: research

Atrial fibrillation in immigrant groups: a cohort study of all adults 45  years of age and older in Sweden
In conclusion, we observed substantial differences in incidence of AF between immigrant groups and the Swedish-born population. A greater awareness of the increased risk of AF development in some immigrant groups may enable for a timely diagnos is, treatment and prevention of its debilitating complications, such as stroke.
Source: European Journal of Epidemiology - July 12, 2017 Category: Epidemiology Source Type: research

DL-2-amino-3-phosphonopropionic acid protects primary neurons from oxygen-glucose deprivation induced injury.
This study was aimed to explore the role of DL-AP3 in primary neuronal cell cultures. Primary neurons were divided into four groups: (1) a control group that was not treated; (2) DL-AP3 group treated with 10 μM of DL-AP3; (3) OGD group, in which neurons were cultured under OGD conditions; and (4) OGD + DL-AP3 group, in which OGD model was first established and then the cells were treated with 10 μM of DL-AP3. Neuronal viability and apoptosis were measured using Cell Counting Kit-8 and flow cytometry. Expressions of phospho-Akt1 (p-Akt1) and cytochrome c were detected using Western blot. The results showed that DL-AP3...
Source: Bosnian Journal of Basic Medical Sciences - December 16, 2016 Category: Journals (General) Tags: Bosn J Basic Med Sci Source Type: research

Progress on diabetic cerebrovascular diseases.
Authors: Zhou H, Zhang X, Lu J Abstract Diabetic cerebrovascular diseases are defined as cerebral vascular diseases induced by diabetes with sugar, fat and a series of nutrient substance metabolic disorders, resulting in intracranial large and small vessel diseases. About 20%-40% patients with type 2 diabetes suffer from cerebral blood vessel diseases. Diabetic cerebrovascular diseases are the main causes of death in patients with diabetes mellitus. The major clinical manifestations are asymptomatic cerebral atherosclerosis, stroke, cerebral small vessel disease and acute cerebral vascular disease. The pathogenesis...
Source: Bosnian Journal of Basic Medical Sciences - December 20, 2015 Category: Journals (General) Tags: Bosn J Basic Med Sci Source Type: research

Elevation in circulating YKL-40 concentration in patients with cerebrovascular disease.
Authors: Xu X, Ma H, Xu J, Huang H, Wu X, Xiong Y, Zhan H, Huang F Abstract YKL-40 is a novel inflammatory protein. Elevated serum levels of YKL-40 have been reported in patients with atherosclerosis and other cardiovascular diseases, but the circulating profile of YKL-40 in patients with cerebrovascular disease has been less investigated. This prospective observational study aimed to determine serum levels of YKL-40 in patients with different subtypes and severities of cerebrovascular disease. Eighty patients with acute ischemic stroke, 30 patients with acute hemorrhagic stroke, 15 patients with transient ischemic...
Source: Bosnian Journal of Basic Medical Sciences - December 20, 2015 Category: Journals (General) Tags: Bosn J Basic Med Sci Source Type: research