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Total 129 results found since Jan 2013.

Minimal Adherence Threshold to Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation to Reduce the Risk of Thromboembolism and Death: A Nationwide Cohort Study
ConclusionPoor adherence to NOACs is associated with increased risks of thromboembolism and all-cause mortality. The minimal adherence threshold should be ≥ 90%, preferably even ≥ 95%.
Source: Cardiovascular Drugs and Therapy - September 14, 2023 Category: Cardiology Source Type: research

The Impact of Polypharmacy on the Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation
CONCLUSION: Polypharmacy was associated with increased thromboembolic, bleeding, and mortality risks in AF patients. NOACs had better benefit-risk profiles than VKAs in patients with polypharmacy.PMID:37369234 | DOI:10.1055/s-0043-1769735
Source: Thrombosis and Haemostasis - June 27, 2023 Category: Hematology Authors: Maxim Grymonprez Mirko Petrovic Tine L De Backer Stephane Steurbaut Lies Lahousse Source Type: research

Mechanical thrombectomy is cost-effective versus medical management alone around Europe in patients with low ASPECTS
Conclusions MT is efficient versus MM alone for patients with low ASPECTS in eight countries across Europe. Patients with a large ischemic core could be treated with MT because it is both clinically beneficial and economically sustainable.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Moreu, M., Scarica, R., Perez-Garcia, C., Rosati, S., Lopez-Frias, A., Egido, J. A., Gomez-Escalonilla, C., Simal, P., Arrazola, J., Bocquet, A.-L., Barthe, T. Tags: Open access, Ischemic stroke Source Type: research

K9 dies while officers conduct active shooter training at high school
A K9 police dog has died in Cobb County, Georgia, after suffering from heat stroke during a training exercise on Monday, officials report. Chase, a 4-year-old Belgian Malinois, was found unresponsive in the patrol vehicle by officers following a malfunction in the vehicle's air conditioning…#k9 #cobbcounty #georgia #chase #belgianmalinois #k9chase #officerneill #allatoonahighschool #acworth #cobbofficers
Source: Reuters: Health - June 7, 2023 Category: Consumer Health News Source Type: news

Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) in adults with chronic stroke: protocol of a randomised controlled trial
This study will compare the effect of 50 hours of HABIT-ILE against usual motor activity and regular rehabilitation. HABIT-ILE will be provided in a 2-week, adult’s day-camp setting, promoting functional tasks and structured activities. These tasks will continuously progress by increasing their difficulty. Assessed at baseline, 3 weeks after and at 3 months, the primary outcome will be the adults-assisting-hand-assessment stroke; secondary outcomes include behavioural assessments for hand strength and dexterity, a motor learning robotic medical device for quality of bimanual motor control, walking endurance, question...
Source: BMJ Open - April 13, 2023 Category: General Medicine Authors: Ebner-Karestinos, D., Gathy, E., Carton de Tournai, A., Herman, E., Araneda, R., Dricot, L., Macq, B., Vandermeeren, Y., Bleyenheuft, Y. Tags: Open access, Rehabilitation medicine Source Type: research

Cardiovascular comorbidities in psoriatic arthritis: epidemiology and risk factors in two different European populations
CONCLUSIONS: The prevalence of AH, T2D and CV diseases were higher in Italian patients rather than Belgians. Moreover, among patients with PsA, the risk of AH was higher in the Italian cohort compared to the Belgian cohort. These results suggest that further research is needed to evaluate potential extrinsic factors (geography and sociocultural aspects) that may contribute to CV risk.PMID:36826796 | DOI:10.55563/clinexprheumatol/aovika
Source: Clinical and Experimental Rheumatology - February 24, 2023 Category: Rheumatology Authors: Silvia Scriffignano Rik Lories Adrien Nzeusseu Toukap Ennio Lubrano Francesco Ciccia Serge Steinfeld Fabio Massimo Perrotta Ilenia Pantano Filip Van den Bosch Kurt de Vlam Source Type: research

Inappropriate Combined Antiplatelet and Anticoagulant Therapy in Older Patients with Atrial Fibrillation: Trend over Time (2009 –18)
ConclusionsWhile inappropriate combined antiplatelet and anticoagulant therapy has declined over the last decade, there is still room for improvement. Antiplatelet deprescribing should be considered in all patients with inappropriate combined antiplatelet and anticoagulant therapy, including those with vascular disease and no recent cardiovascular event.
Source: Drugs and Aging - February 23, 2023 Category: Geriatrics Source Type: research

Long-term comparative effectiveness and safety of dabigatran, rivaroxaban, apixaban and edoxaban in patients with atrial fibrillation: A nationwide cohort study
Conclusion: NOACs had better long-term risk-benefit profiles than VKAs. While effectiveness was comparable, apixaban was overall associated with a more favorable safety profile followed by dabigatran.
Source: Frontiers in Pharmacology - February 2, 2023 Category: Drugs & Pharmacology Source Type: research

Postdischarge prognostic significance of periprocedural myocardial injury after percutaneous intervention of chronic total occlusion
CONCLUSION: Periprocedural myocardial injury was associated with a significantly higher rate of MACCE and all-cause mortality after 12 months of FU.PMID:36600648 | DOI:10.1136/openhrt-2022-002113
Source: Atherosclerosis - January 5, 2023 Category: Cardiology Authors: Ella Poels Maarten Vanhaverbeke Deborah van den Buijs Daan Cottens Koen Ameloot Pierluigi Lesizza Keir McCutcheon Johan Bennet Joseph Dens Source Type: research

Multicentric validation of a reduced features case-mix set for predicting functional outcome after ischemic stroke in Belgium
DiscussionThe reduced features set (age, NIHSS and pre-mRS) was independently associated with long-term functional outcome in a Belgian multicentric cohort, making it useful for case-mix adjustments in Belgian stroke centers. Treatment modality was associated with long-term outcome.
Source: Acta Neurologica Belgica - November 21, 2022 Category: Neurology Source Type: research