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Total 61 results found since Jan 2013.

Thousands of excess deaths from cardiovascular disease during the COVID-19 pandemic
(University of Leeds) Thousands of excess deaths from cardiovascular disease during the COVID-19 pandemic A major new study has identified 2085 excess deaths in England and Wales due to heart disease and stroke during the peak of the COVID-19 pandemic. On average, that is 17 deaths each day over four months that probably could have been prevented.
Source: EurekAlert! - Infectious and Emerging Diseases - September 28, 2020 Category: Infectious Diseases Source Type: news

Rhod Gilbert health: Comedian suffered suspected ‘mini-stroke’ - symptoms you need to spot
RHOD GILBERT, the Welsh comedian, experienced a suspected ‘mini-stroke' back in 2017. But what is the condition, is it life-threatening and what are the symptoms to look out for?
Source: Daily Express - Health - August 21, 2020 Category: Consumer Health News Source Type: news

Physiotherapists' experiences of early mobilization after stroke thrombolysis in England and Wales: A qualitative study.
CONCLUSIONS: Physiotherapists describe a variety of practices with careful implementation of any early mobilization after thrombolysis. Common factors of risk assessment reported by participants could contribute to guideline development. PMID: 32735467 [PubMed - as supplied by publisher]
Source: Physiotherapy Theory and Practice - July 30, 2020 Category: Physiotherapy Authors: Turner N, Pickering D, Jones K Tags: Physiother Theory Pract Source Type: research

Oxygen sensing; a stunningly elegant molecular machinery highjacked in cancer.
Abstract Oxygen is of fundamental importance for most living organisms, and the maintenance of oxygen homeostasis is a key physiological challenge for all large animals. Oxygen deprivation, hypoxia, is a critical component of many human diseases including cancer, heart disease, stroke, vascular disease, and anaemia. The discovery of oxygen sensing provides fundamental knowledge of a stunningly elegant molecular machinery; it also promises development of new therapeutics for serious diseases such as cancer. As a result of their impressive contributions to our understanding of the mechanisms by which cells sense oxy...
Source: Upsala Journal of Medical Sciences - June 23, 2020 Category: General Medicine Authors: Claesson-Welsh L Tags: Ups J Med Sci Source Type: research

Population-based stroke surveillance using big data: state-wide epidemiological trends in admissions and mortality in New South Wales, Australia.
DISCUSSION: Improved prevention may have underpinned declining intracerebral haemorrhage rates while survival gains suggest that innovations in care are being successfully translated. Mortality in patients surviving the acute period is unchanged and may be increasing for subarachnoid haemorrhage warranting investment in post-discharge care and secondary prevention. PMID: 32449879 [PubMed - as supplied by publisher]
Source: Neurological Research - May 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Evaluation of the MCAST, a multidisciplinary toolkit to improve mental capacity assessment.
Conclusions: The MCAST is the first toolkit to support the needs of individuals with communication disabilities during mental capacity assessments. It enables assessors to deliver high quality, legally compliant and confident practice.IMPLICATIONS FOR REHABILITATIONMental capacity assessment practice needs to be improved to maximise patient autonomy, safety and well-being.The MCAST is a paper-based toolkit designed to facilitate and improve mental capacity practice in England and Wales.This study suggests the MCAST would be easy and acceptable to use in healthcare settings and could lead to improvements in assessment quali...
Source: Disability and Rehabilitation - May 22, 2020 Category: Rehabilitation Authors: Jayes M, Palmer R, Enderby P Tags: Disabil Rehabil Source Type: research

Rivaroxaban Plus Aspirin Versus Aspirin Alone in Patients with Prior Percutaneous Coronary Intervention (COMPASS-PCI).
Conclusions: DPI compared with aspirin produced consistent reductions in MACE and mortality but with increased major bleeding with or without prior PCI. Among those with prior PCI one- year and beyond, effects on MACE and mortality were consistent irrespective of time since last PCI. Clinical Trial Registration: URL: www.ClinicalTrials.gov Unique Identifier: NCT01776424. PMID: 32178526 [PubMed - as supplied by publisher]
Source: Circulation - March 16, 2020 Category: Cardiology Authors: Bainey KR, Welsh RC, Connolly SJ, Marsden T, Bosch J, Fox KAA, Steg PG, Vinereanu D, Connolly DL, Berkowitz SD, Foody JM, Probstfield JL, Branch KR, Lewis BS, Diaz R, Muehlhofer E, Widimsky P, Yusuf S, Eikelboom JW, Bhatt DL, COMPASS Investigators Tags: Circulation Source Type: research

No Evidence of the “Weekend Effect” in the Northern New South Wales Telestroke Network
Conclusions: The weekend effect is not evident in the Northern NSW telestroke network experience, though this study did identify some opportunities for improvement in the delivery of acute stroke therapies.
Source: Frontiers in Neurology - February 25, 2020 Category: Neurology Source Type: research

Heart attack, stroke and burns victims wait up to FIVE HOURS for an ambulance
One in 16 seriously ill patients in England and Wales wait more than an hour for emergency services to arrive - 4,000 per week, a BBC investigation found.
Source: the Mail online | Health - January 29, 2020 Category: Consumer Health News Source Type: news

Stroke consultant shortage 'hurtling towards crisis'
Some 48% of hospitals in England, Wales and Northern Ireland do not have the staff they need, figures suggest.
Source: BBC News | Health | UK Edition - January 17, 2020 Category: Consumer Health News Source Type: news

Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study.
CONCLUSION: Multiple complications after surgery for lower limb PAD carried a compounding risk of reduced long term amputation free survival. Patients experiencing at least one complication form a high risk group that requires increased attention to prevent the potential development of further complications. PMID: 31879146 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - December 22, 2019 Category: Surgery Authors: Aitken SJ, Randall DA, Noguchi N, Blyth FM, Naganathan V Tags: Eur J Vasc Endovasc Surg Source Type: research

Intercellular Conduction Optimizes Arterial Network Function and Conserves Blood Flow Homeostasis During Cerebrovascular Challenges.
CONCLUSIONS: Our findings highlight the integral role of intercellular electrical signaling in transcribing focal stimuli into coordinated changes in cerebrovascular contractile activity and expose, a hitherto unknown mechanism for flow regulation after stroke. PMID: 31826653 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - December 11, 2019 Category: Cardiology Authors: Zechariah A, Tran CHT, Hald BO, Sandow SL, Sancho M, Kim MSM, Fabris S, Tuor UI, Gordon GRJ, Welsh DG Tags: Arterioscler Thromb Vasc Biol Source Type: research

Applying contemporary antithrombotic therapy in the secondary prevention of chronic atherosclerotic cardiovascular disease
Publication date: Available online 23 October 2019Source: American Heart JournalAuthor(s): Robert C. Welsh, Eric D. Peterson, Raffaele De Caterina, Christoph Bode, Bernard Gersh, John W. EikelboomAbstractFor four decades, anti-thrombotic therapy with aspirin has been a cornerstone of secondary prevention for patients with chronic atherosclerotic cardiovascular disease (ASCVD). Unfortunately, despite the use of evidence-based therapies, patients with ASCVD continue to have recurrent major adverse cardiovascular (CV) events including death, myocardial infarction and stroke -- at a rate of approximately 2–4% per year. To co...
Source: American Heart Journal - October 24, 2019 Category: Cardiology Source Type: research

Type A aortic dissection in patients over the age of seventy in the UK
ConclusionsATAD is a life ‐threatening condition with a high mortality rate if left untreated. Our results show that surgery for ATAD in patients over 70 is feasible with acceptable mortality rates. However, similar to previous studies, rates of stroke in older patients may be higher. The present study supports the notion that age should not be a discriminating factor in operating on patients with TAAD.
Source: Journal of Cardiac Surgery - October 15, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Mohamad Bashir, Amer Harky, Matthew Shaw, Benjamin Adams, Aung Oo Tags: ORIGINAL ARTICLE Source Type: research

Outcomes Among Clopidogrel, Prasugrel, and Ticagrelor in ST-Elevation Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention From the TOTAL Trial
ConclusionsIn this observational analysis of STEMI patients who underwent primary percutaneous coronary intervention, ticagrelor was associated with improved outcomes compared with clopidogrel and prasugrel. An appropriately powered randomized trial is needed to confirm these findings.RésuméContexteIl n’existe pas d’analyse robuste comparant les inhibiteurs P2Y12 à prise orale (clopidogrel, prasugrel et ticagrélor) chez les patients ayant subi un infarctus du myocarde avec élévation du segment ST (STEMI) traités par une intervention coronaire percutanée (ICP) primaire. Nous avons entrepris d’évaluer les rés...
Source: Canadian Journal of Cardiology - October 9, 2019 Category: Cardiology Source Type: research

Inclusion of a care bundle for fever, hyperglycaemia and swallow management in a National Audit for acute stroke: evidence of upscale and spread
In the Quality in Acute Stroke Care (QASC) trial undertaken in stroke units (SUs) located in New South Wales (NSW), Australia (2005 –2010), facilitated implementation of a nurse-led care bundle to manage fever,...
Source: Implementation Science - September 2, 2019 Category: Health Management Authors: Tara Purvis, Sandy Middleton, Louise E. Craig, Monique F. Kilkenny, Simeon Dale, Kelvin Hill, Catherine D ’Este and Dominique A. Cadilhac Tags: Research Source Type: research

Atrial fibrillation with percutaneous coronary intervention: Navigating the minefield of antithrombotic therapies
This review aims to provide insights into contemporary therapeutic options for the treatment of patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) and compares current international guidelines. AF is a common cardiac arrhythmia and a major risk factor for stroke. The risk of stroke can be reduced with the use of oral anticoagulant (OAC) therapy. However, for patients with AF, PCI necessitates the use of combined antithrombotic therapies (OAC and antiplatelet therapies) to reduce thrombotic coronary complications.
Source: Atherosclerosis - August 29, 2019 Category: Cardiology Authors: Kevin R. Bainey, Jo ão Morais, Uwe Zeymer, Robert C. Welsh Tags: Review article Source Type: research

Googling Location for Operating Base of Mobile Stroke Unit in Metropolitan Sydney
Conclusions: Any of the ECR capable hospital can serve as a hub for MSU. We provide a method to identify the hub based on location of suburbs less well served by other hospital.
Source: Frontiers in Neurology - August 5, 2019 Category: Neurology Source Type: research

Googling service boundaries for Endovascular Clot Retrieval (ECR) hub hospitals in metropolitan Sydney
Conclusions: The simulation studies supported a minimum of 4 ECR hubs servicing Sydney. This model provides data on number of suburbs and population at risk of stroke that can reach these hubs within 30 minutes.
Source: Frontiers in Neurology - July 1, 2019 Category: Neurology Source Type: research

Is Incorrect Anti-Coagulation Dosing Contributing to Ischaemic Stroke Burden? A Retrospective Single-Centre Study from Regional New South Wales, Australia
Background: Atrial fibrillation (AF) contributes to 30% of ischaemic stroke presentations. Low doses of anti-coagulants are often prescribed to prevent stroke but ameliorate bleeding risk.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: P. Bamford, M. Ray, S. Cheruvu, M. Parkinson, C. Said, J. Trappel, J. Rogers Tags: 195 Source Type: research

Outcomes Among Clopidogrel, Prasugrel, And Ticagrelor In Stemi Patients Undergoing Primary Percutaneous Coronary Intervention From The Total Trial
ConclusionsIn this observational analysis of STEMI patients undergoing PPCI, ticagrelor was associated with improved outcomes compared to clopidogrel and prasugrel. An appropriately powered randomized trial is needed to confirm these findings.
Source: Canadian Journal of Cardiology - May 8, 2019 Category: Cardiology Source Type: research

Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves. Introduction Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1 1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

A Novel Triple-Cell Two-Dimensional Model to Study Immune-Vascular Interplay in Atherosclerosis
Conclusions We have developed a co-culture model for the study of the immune-vascular interplay in atherosclerosis consisting of ECs, SMCs and an inflammatory compartment. In order to validate this model, we have demonstrated that the triple-cell 2D culture of ECs, SMCs, and THP-1 macrophage-like cells significantly alters the phenotype of ECs and SMCs within this culture in comparison with EC/SMC, EC/THP-1, or SMC/THP-1 double-cell cultures. Our results are indicative of the multi-directional communication between highly plastic vascular stromal cells and the immune system, which is now well recognized in the field, and ...
Source: Frontiers in Immunology - April 23, 2019 Category: Allergy & Immunology Source Type: research

Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Phagocytosis in the Brain: Homeostasis and Disease
Conclusions and Perspectives In this review we have summarized the critical role phagocytosis plays in both CNS homeostasis and disease. While much progress has been made in recent years, many unanswered questions remain. How phagocytosis in the CNS is influenced by numerous factors, such as microenvironment or phagocytic target, have yet to be fully resolved. Additionally, the utilization of novel technologies, including in vivo imaging techniques (217), iPSC-derived microglia (213) and high-throughput screens (66), will likely contribute to further identification of phagocytic pathways and consequences of phagocytosis w...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

When Time Is Critical: How Involving Frontline Health Workers Can Improve Stroke Survival Rates
By Carmen Graffagnino, Neurologist, Duke Hospital ; Nilima Mehta , Philanthropy program manager, Medtronic Foundation ; Anne Katharine Wales, Senior philanthropy portfolio lead, Medtronic FoundationApril 09, 2019Here are three ways to change a system of acute care.April 10 started as an ordinary day for Sarah. But while eating breakfast, her husband noticed that her face had started to droop and she was unable to find her words. Immediately he called 911.Within 10 minutes, the ambulance arrived with emergency medical services (EMS), a segment of the local health system that recently became partners in a new regional ...
Source: IntraHealth International - April 9, 2019 Category: International Medicine & Public Health Authors: mnathe Tags: Noncommunicable Diseases Education & Performance Private-Sector Approaches SwitchPoint Health Workforce Systems USA Source Type: news

Understanding determinants of acute stroke thrombolysis using the tailored implementation for chronic diseases framework: a qualitative study
The Tailored Implementation in Chronic Disease (TICD) framework is a comprehensive framework describing the determinants of implementation success that has been used extensively in primary care settings. We ex...
Source: BMC Health Services Research - March 20, 2019 Category: General Medicine Authors: Lesli E. Skolarus, Gina M. Neshewat, Lacey Evans, Molly Green, Narmeen Rehman, Zach Landis-Lewis, Jillian Welsh Schrader and Anne E. Sales Tags: Research article Source Type: research

Primary therapy of Graves' disease and cardiovascular morbidity and mortality: a linked-record cohort study
Publication date: Available online 28 February 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Onyebuchi E Okosieme, Peter N Taylor, Carol Evans, Dan Thayer, Aaron Chai, Ishrat Khan, Mohd S Draman, Brian Tennant, John Geen, Adrian Sayers, Robert French, John H Lazarus, Lakdasa D Premawardhana, Colin M DayanSummaryBackgroundGraves' disease is routinely treated with antithyroid drugs, radioiodine, or surgery, but whether the choice of initial therapy influences long-term outcomes is uncertain. We evaluated cardiovascular morbidity and mortality according to the method and effectiveness of primary therapy in Graves'...
Source: The Lancet Diabetes and Endocrinology - March 1, 2019 Category: Endocrinology Source Type: research

A prospective study of health conditions related to alcohol consumption cessation among 97,852 drinkers aged 45 and over in Australia.
CONCLUSIONS: Diagnosis with a variety of health conditions appears to prompt drinking cessation in older adults. This article is protected by copyright. All rights reserved. PMID: 30758044 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - February 13, 2019 Category: Addiction Authors: Sarich P, Canfell K, Banks E, Paige E, Egger S, Joshy G, Korda R, Weber M Tags: Alcohol Clin Exp Res Source Type: research

Three-year-old girl's chickenpox caused her to have a STROKE
Lottie Evans was staying at a caravan park in Abersoch, North Wales, with her family on July 26, 2016 when she became clumsy, irritable and unable to walk.
Source: the Mail online | Health - February 6, 2019 Category: Consumer Health News Source Type: news

Returning to Unpaid Work after Stroke: The Psychosocial Outcomes in Stroke Cohort Study
Conclusions: More women are engaged in unpaid work before and at 12 months after stroke, but there is a reduction in the proportion of women returning to unpaid work at 12 months not seen in men. Consideration may need to be given to the development of rehabilitation strategies targeted at the specific needs of stroke survivors.Cerebrovasc Dis 2019;47:1 –7
Source: Cerebrovascular Diseases - January 17, 2019 Category: Neurology Source Type: research

Maximising data value and avoiding data waste: a validation study in stroke research.
CONCLUSION: We report the first linkage of data from an Australian national clinical quality disease registry with routinely collected data from several national and state government health datasets. Data linkage enriches the clinical registry dataset and provides additional information beyond that for the acute care setting and quality of life at follow-up, allowing clinical outcomes for people with stroke (mortality and hospital contacts) to be more comprehensively assessed. PMID: 30636305 [PubMed - in process]
Source: Med J Aust - January 1, 2019 Category: General Medicine Authors: Kilkenny MF, Kim J, Andrew NE, Sundararajan V, Thrift AG, Katzenellenbogen JM, Flack F, Gattellari M, Boyd JH, Anderson P, Lannin N, Sipthorp M, Chen Y, Johnston T, Anderson CS, Middleton S, Donnan GA, Cadilhac DA Tags: Med J Aust Source Type: research

Report says hospital discharge must improve
Health inspectors in Wales say poor IT is stopping GPs getting right information Related items fromOnMedica Eight in ten stillbirths might have been avoided NHS is failing patients with mental health problems Avoidable harm still ‘too high’ in UK healthcare Primary Care Home has positive impact on care and services Stroke survivors need more help taking medicine
Source: OnMedica Latest News - August 15, 2018 Category: UK Health Source Type: news

20 years of researching stroke through audit.
This article records and reviews some questions that have been answered using data from the audit: Is the rate of institutional care after rehabilitation a possible measure of outcome? Does stroke unit care in routine practice give the benefits shown in randomized controlled trials? How is the quality of stroke care affected by a patient's age and the time of their stroke? Do patient-reported measures match those obtained from the professionals recording of processes of care? How do the processes of care after stroke affect mortality? Is thrombolysis safe to use in patients over the age of 80? Do staffing levels matter? Do...
Source: Clinical Rehabilitation - June 1, 2018 Category: Rehabilitation Authors: Rudd AG, Hoffman A, Paley L, Bray B Tags: Clin Rehabil Source Type: research

Beyond Stroke Prevention in Atrial Fibrillation: Exploring Further Unmet Needs with Rivaroxaban.
This article provides an update on three randomized controlled trials of rivaroxaban, a direct, oral factor Xa inhibitor, that are complete or are ongoing, in these unmet areas of stroke prevention: oPen-label, randomized, controlled, multicentre study explorIng twO treatmeNt stratEgiEs of Rivaroxaban and a dose-adjusted oral vitamin K antagonist treatment strategy in patients with Atrial Fibrillation who undergo Percutaneous Coronary Intervention (PIONEER AF-PCI) trial; the New Approach riVaroxaban Inhibition of factor Xa in a Global trial vs Aspirin to prevenT Embolism in Embolic Stroke of Undetermined Source (NAVIGATE E...
Source: Thrombosis and Haemostasis - March 22, 2018 Category: Hematology Authors: Gibson CM, Hankey GJ, Nafee T, Welsh RC Tags: Thromb Haemost Source Type: research

Early outcomes of patients transferred with ruptured suprarenal aneurysm or dissection.
Conclusions Although the number of patients with rSRAD is low and those who are transferred alive are a self-selecting group, this study suggests that transfer of such patients to a specialist vascular centre is associated with acceptable mortality rates following emergency complex aortic repair. PMID: 29484940 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - February 27, 2018 Category: Surgery Authors: Rudarakanchana N, Hamady M, Harris S, Afify E, Gibbs R, Bicknell CD, Jenkins MP Tags: Ann R Coll Surg Engl Source Type: research

Impact of intracranial artery calcification on cerebral hemodynamic changes
ConclusionHeavier IAC might cause generalized artery flow velocity changes and increased pulsatility index, which may indicate high resistance within cerebrovasculature.
Source: Neuroradiology - February 9, 2018 Category: Radiology Source Type: research

Ticagrelor for Secondary Prevention of Atherothrombotic Events After Myocardial Infarction: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
AbstractThe National Institute for Health and Care Excellence (NICE) invited AstraZeneca, the manufacturer of ticagrelor (Brilique®), to submit evidence on the clinical and cost effectiveness of ticagrelor 60  mg twice daily (BID) in combination with low-dose aspirin [acetylsalicylic acid (ASA)] compared with ASA only for secondary prevention of atherothrombotic events in patients with a history of myocardial infarction (MI) and who are at increased risk of atherothrombotic events. Kleijnen Systematic R eviews Ltd (KSR), in collaboration with Maastricht University Medical Centre+, was commissioned as the evidence review ...
Source: PharmacoEconomics - January 18, 2018 Category: Health Management Source Type: research

Rising to the Challenge: Stroke care received between April 2016 to March 2017 The Fourth SSNAP Annual Report
The report highlights the improvements made in stroke care in England, Wales and Northern Ireland over the past four years. Using real world quality improvement case studies, it outlines the different approaches taken by local teams to improve their stroke services across the patient pathway; what was the challenge faced? What was the solution? What impact did the QI project have on care processes? The report also offers practical tips and recommendations on how other clinical teams could adapt similar QI approaches to improve the care provided to their patients in the future.
Source: Current Awareness Service for Health (CASH) - December 8, 2017 Category: Consumer Health News Source Type: news

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Risk factors for falls among older Aboriginal and Torres Strait Islander people in urban and regional communities.
CONCLUSION: Falls were experienced by one-quarter of study participants. Fall risk factors identified for older Aboriginal people appear to be similar to those identified in the general population. Understanding of fall risk factors may assist with the development of appropriate and effective community-led fall prevention programs. PMID: 29143435 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - November 15, 2017 Category: Geriatrics Authors: Lukaszyk C, Radford K, Delbaere K, Ivers R, Rogers K, Sherrington C, Tiedemann A, Coombes J, Daylight G, Draper B, Broe T Tags: Australas J Ageing Source Type: research

Risk factors for falls among older Aboriginal and Torres Strait Islander people in urban and regional communities
ConclusionFalls were experienced by one‐quarter of study participants. Fall risk factors identified for older Aboriginal people appear to be similar to those identified in the general population. Understanding of fall risk factors may assist with the development of appropriate and effective community‐led fall prevention programs.
Source: Australasian Journal on Ageing - November 15, 2017 Category: Geriatrics Authors: Caroline Lukaszyk, Kylie Radford, Kim Delbaere, Rebecca Ivers, Kris Rogers, Catherine Sherrington, Anne Tiedemann, Julieann Coombes, Gail Daylight, Brian Draper, Tony Broe Tags: Research Article Source Type: research

Sight Impairment registration due to stroke —A small yet significant rise?
ConclusionsThese data suggest a small but statistically significant increase in the incidence of certifiable visual impairment due to stroke between 2008 and 2014. Figures are, however, considerably lower than estimated, perhaps suggesting that more should be done to address the visual needs of those who have suffered stroke. In the United Kingdom, there was a significant increase in the incidence of certifiable visual impairment due to stroke between 2008 and 2014. Figures are, however, considerably lower than estimated, perhaps suggesting that more should be done to address the visual needs of those who have suffered stroke.
Source: Brain and Behavior - October 29, 2017 Category: Neurology Authors: Catey Bunce, Antra Zekite, Richard Wormald, Fiona Rowe Tags: ORIGINAL RESEARCH Source Type: research

130 Improving the implementation of anti-coagulation therapy in AF patients at risk of stroke in a primary care setting
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia of the heart and is of increasing prevalence1. There are strong implications of increased stroke risk in AF patients2. In particular, AF related stroke carries a near 50% risk of persisting disability and directly increases costs for treatment by over a third in comparison with non AF stroke patients3,4. As an estimated contributing cause of 15-20% of all strokes, the economic and societal impact of AF is of extreme importance5. To monitor how efficiently stroke prevention is implemented in a primary care setting we will identify those ‘at risk...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

Stroke patients in Wales ‘could die’ because thrombectomy not available
Acute shortage in NHS of specialist doctors who undertake life-saving treatment means hospitals cannot provide itStroke patients in Wales are being denied a life-saving pioneering treatment after the surgical team providing it had to be mothballed because of an acute NHS shortage of the specialist doctors who undertake the procedure.Internal NHS emails obtained by the Guardian reveal that health service bosses in Wales are pleading with hospitals in England to perform mechanical thrombectomy on their patients to save them from disability and death.Continue reading...
Source: Guardian Unlimited Science - October 1, 2017 Category: Science Authors: Denis Campbell Health policy editor Tags: Stroke NHS Wales Health Medical research Society Doctors Science UK news Source Type: news

Study offers a new mindset in the search for stroke therapies
(University of New South Wales) UNSW researchers have identified a promising new avenue to explore in the search for stroke treatments, after translating findings from Alzheimer's disease.
Source: EurekAlert! - Medicine and Health - September 7, 2017 Category: International Medicine & Public Health Source Type: news

Speed increases risk of stroke within hours or days of use
Methamphetamine can raise blood pressure, making users more susceptible to a hemorrhagic stroke, found a study by the University of New South Wales in Australia.
Source: the Mail online | Health - August 31, 2017 Category: Consumer Health News Source Type: news

Welsh nurse rewarded for stroke service.
Authors: Abstract A ward sister at a Welsh health board has been named RCN Wales nurse of the year for improving the care of stroke patients. PMID: 26602645 [PubMed - in process]
Source: Nursing Standard - November 25, 2015 Category: Nursing Tags: Nurs Stand Source Type: research