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Total 3248 results found since Jan 2013.

An Inflection Point for Stroke Care
In the past six months, stroke care in the United States has taken an epoch-changing turn. Techniques, technologies, and treatment pathways hinted at in earlier trials have become fully vetted and are a new gold standard giving doctors more time to treat stroke patients and help them regain pre-stroke capabilities. Two recent trials, especially, DAWN and DEFUSE 3, have precipitated industry-wide shifts in the way hospitals treat stroke, especially acute ischemic stroke. "I guess the best thing I can say is we have altered our practice here, essentially immediately, based on the results of those studies. I guess that shows ...
Source: MDDI - April 2, 2018 Category: Medical Devices Authors: Greg Goth Tags: Cardiovascular Source Type: news

Roles of integrins and extracellular matrix in stroke.
Abstract Ischemic stroke is a leading cause of death and disability in the United States, but recent advances in treatments (i.e. endovascular thrombectomy and tissue plasminogen activator (t-PA)) that target the stroke-causing blood clot, while improving overall stroke mortality rates, have had much less of an impact on overall stroke morbidity. This may in part be attributed to the lack of therapeutics targeting reperfusion induced injury after the blood clot has been removed, which, if left unchecked, can expand injury from its core into the surrounding at risk tissue (penumbra). This occurs in two phases of in...
Source: Am J Physiol Cell Ph... - November 21, 2018 Category: Cytology Authors: Edwards D, Bix GJ Tags: Am J Physiol Cell Physiol Source Type: research

Nerve stimulation could provide new treatment option for most common type of stroke
Research led by a UCLA scientist found that a new nerve stimulation therapy to increase blood flow could help patients with the most common type of stroke up to 24 hours after onset.A study of 1,000 patients found evidence that the technique, called active nerve cell cluster stimulation, reduced the patients ’ degree of disability three months after they suffered an acute cortical ischemic stroke, which affects the surface of the brain.Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center, was the co-principal investigator of the study, which was conducted at 73 medical centers in 18 countries.“We believe ...
Source: UCLA Newsroom: Health Sciences - May 24, 2019 Category: Universities & Medical Training Source Type: news

Time to Target Stroke: Examining the Circadian System in Stroke.
Authors: Stubblefield JJ, Lechleiter JD Abstract Stroke is the 5th leading cause of death in the United States and a leading cause of long-term disability. Ischemic strokes account for 87 percent of total stroke cases, yet the only FDA-approved treatments involve disruption of the blood clot to restore blood flow. New treatments aimed at saving or protecting neural tissue have largely failed in clinical trials and so new methodology or targets must be found. The occurrence of strokes significantly increases between 6 AM and 12 PM, implicating the circadian system in the onset of this debilitating brain injury. But ...
Source: The Yale Journal of Biology and Medicine - July 1, 2019 Category: Universities & Medical Training Tags: Yale J Biol Med Source Type: research

Use of insertable cardiac monitors for the detection of atrial fibrillation in patients with cryptogenic stroke in the United States is cost-effective.
Authors: Maervoet J, Bossers N, Borge RP, Thompson Hilpert S, van Engen A, Smala A Abstract Atrial fibrillation (AF) is the most common arrhythmia and a major marker of stroke risk. Early detection is crucial and, once diagnosed, anticoagulation therapy can be initiated to reduce stroke risk. The aim of this study was to assess the cost-effectiveness of employing an insertable cardiac monitor (ICM), BIOMONITOR, for the detection of AF compared to standard of care (SoC) ECG and Holter monitoring in patients with cryptogenic stroke, that is, stroke of unknown origin and where paroxysmal, silent AF is suspected. A Mar...
Source: Journal of Medical Economics - September 6, 2019 Category: Health Management Tags: J Med Econ Source Type: research

Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk
Conclusion. . With the increase of spinal procedures, it is important to identify patients at risk for having an ischemic stroke and to optimize their comorbidities preoperatively. Patients with intraoperative ischemic stroke carry a higher risk for morbidity and mortality during the index hospitalization. Level of Evidence: 4
Source: Spine - January 8, 2020 Category: Orthopaedics Tags: CLINICAL CASE SERIES Source Type: research

Impact of a Structured Response and Evidence-Based Checklist on In-hospital Stroke Outcomes
CONCLUSIONS Use of a checklist during inpatient stroke events can potentially increase adherence to guidelines for appropriate treatment and reduce mortality. Hospital response teams should consider use of a structured response system with an evidence-based checklist for high-acuity, low-frequency events such as in-hospital stroke.
Source: Journal of Neuroscience Nursing - April 29, 2020 Category: Neuroscience Tags: Article Source Type: research

Use of the Activity Measure for Post-Acute Care "6 Clicks" Basic Mobility Inpatient Short Form and National Institutes of Health Stroke Scale to Predict Hospital Discharge Disposition After Stroke.
CONCLUSION: The 6 Clicks mobility score alone can guide discharge decision making after stroke, particularly for discharge to home versus an SNF or an IRF. Determining discharge to an SNF versus an IRF could be improved by also considering the NIHSS score, age, sex, and race. Future studies should seek to identify which additional characteristics improve predictability for these separate discharge destinations. IMPACT: The use of outcome measures can improve therapist confidence in making discharge recommendations for people with stroke, can enhance hospital throughput, and can expedite access to rehabilitation, ultim...
Source: Physical Therapy - June 2, 2020 Category: Physiotherapy Authors: Covert S, Johnson JK, Stilphen M, Passek S, Thompson NR, Katzan I Tags: Phys Ther Source Type: research

"Personal road map for recovery:" examining the therapeutic use of weblogs by stroke survivors with aphasia.
CONCLUSION: Weblog writing was therapeutic for stroke survivors with aphasia. Authors reported benefits across cognitive, psychological, emotional, and social domains. Health professionals should consider recommending weblog writing, journaling, or other methods of writing for stroke survivors with aphasia. Implications for rehabilitation Creating illness weblog posts can be therapeutically beneficial for stroke survivors with aphasia as a tool that addresses psychological, emotional, and social aspects in their recovery. Blogging appeared to offer a medium for stroke survivors with aphasia to practice writing, to express ...
Source: Disability and Rehabilitation - August 31, 2020 Category: Rehabilitation Authors: Carcello K, McLennon S Tags: Disabil Rehabil Source Type: research

Practice Patterns and Attitudes Among Speech –Language Pathologists Treating Stroke Patients with Dysphagia: A Nationwide Survey
AbstractDysphagia management is a core component of quality stroke care. Speech –Language Pathologists (SLPs) play a key role in the management of post-stroke dysphagia. We sought to elicit perceptions, attitudes, and practice patterns regarding post-stroke dysphagia management among SLPs in the United States. We conducted a survey among SLPs registered with the American Spee ch–Language–Hearing Association who indicated that they care for acute stroke patients. A total of 336 participants completed the survey. Over half of the participants (58.6%) indicated that they obtain objective swallow testing in ≥ 60% o...
Source: Dysphagia - March 10, 2022 Category: Speech-Language Pathology Source Type: research

Acute Stroke Diagnosis
Am Fam Physician. 2022 Jun 1;105(6):616-624.ABSTRACTStroke accounts for significant morbidity and mortality and is the fifth leading cause of death in the United States, with direct and indirect costs of more than $100 billion annually. Expedient recognition of acute neurologic deficits with appropriate history, physical examination, and glucose testing will help diagnose stroke and rule out mimicking presentations. The National Institutes of Health Stroke Scale should be used to determine stroke severity and to monitor for evolving changes in clinical presentation. Initial neuroimaging is used to differentiate between isc...
Source: American Family Physician - June 15, 2022 Category: Primary Care Authors: Edwin Y Choi Gilberto A Nieves Darrell Edward Jones Source Type: research

The Sky's the Limit: Expanding Nursing's Contribution to Acute Stroke Science
Am J Crit Care. 2022 Jul 1;31(4):266-274. doi: 10.4037/ajcc2022109.ABSTRACTStroke is the number one cause of preventable disability in adults in the United States. Significant advances have occurred in medications and technology supporting rapid stroke diagnosis and treatment during the past 30 years, along with blurring of the lines of what traditionally constituted nursing or medical research. Ischemic stroke is a disease of vascular insufficiency that mirrors myocardial infarction more than any other neurologic diagnosis. My primary program of research is focused on exploration of methods to improve intracranial blood f...
Source: Atherosclerosis - June 30, 2022 Category: Cardiology Authors: Anne W Alexandrov Source Type: research