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Total 236 results found since Jan 2013.

Cost-effectiveness of statin therapy for secondary prevention among patients with coronary artery disease and baseline LDL-C 70–100 mg/dL in Taiwan
ConclusionLowering the target LDL-C level from 100 to 70 mg/dL among treatment-naïve CAD patients could be cost-effective given the health benefits of preventing cardiovascular events and deaths.
Source: Journal of the Formosan Medical Association - February 20, 2020 Category: General Medicine Source Type: research

Oral Anticoagulants and Antiplatelet Agents in Atrial Fibrillation Patients with Concomitant Critical Limb Ischemia: A nationwide cohort study
ConclusionsDOAC was associated with a significantly lower risk of composite net-clinical-benefit outcome than either warfarin or APT in AF patients with concomitant CLI. Further prospective study is necessary to validate the findings in the future.
Source: Canadian Journal of Cardiology - February 19, 2020 Category: Cardiology Source Type: research

Predicting the Risk of Ischemic Stroke among Patients with Rheumatoid Arthritis Using a Simplified RA-CHADSV Score Based on the CHA2DS2-VASc Score.
CONCLUSIONS: A simplified RA-CHADSV score, with comparable efficiency as the CHA2DS2-VASc score, but easier to use clinically was developed for predicting the risk of ischemic stroke among non-AF RA patients. PMID: 32059458 [PubMed - in process]
Source: Medicina (Kaunas) - February 12, 2020 Category: Universities & Medical Training Authors: Hsu CW, Ng KJ, Lu MC, Koo M Tags: Medicina (Kaunas) Source Type: research

Assessment of pre-specified adverse events following varicella vaccine: A population-based self-controlled risk interval study.
CONCLUSIONS: We detected a small risk of incidental pneumonia associated with varicella vaccine in the 6th week after immunization. There was no increase in the risk of other pre-specified adverse events. PMID: 32046891 [PubMed - as supplied by publisher]
Source: Vaccine - February 8, 2020 Category: Allergy & Immunology Authors: Liu CH, Yeh YC, Huang WT, Chie WC, Chan KA Tags: Vaccine Source Type: research

Low Persistence of Antithrombotic Agents is Associated with Poor Outcomes after First-ever Acute Ischemic Stroke.
This study investigated the time-trend persistence with antithrombotic agents (AT) and assessed the impact of AT persistence on outcome events and adverse events (AE) within two years after first-ever acute ischemic stroke (IS). METHODS: Using Taiwan's National Health Insurance claims dataset, 7,341 IS subjects hospitalized between 2001 and 2005 with AT prescribed at discharge and survived at least 3 months were followed up for 2 years. Time-trends of AT usage were analyzed. Medication persistence was assessed as the proportion of days covered (PDC) for filled prescription, and categorized into low, intermediate and hi...
Source: Acta Neurologica Taiwanica - February 7, 2020 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Medication Adherence and Stroke Prevention: What Real World Data Tells Us.
Authors: Hsieh CY Abstract Medication adherence, by definition,(2) is "the extent to which a patient acts in accordance with the prescribed interval and dose of a dosing regimen." Poor medication adherence can interfere with the ability to treat many diseases, leading to greater complications and a lower quality of life.(3) In this issue of Acta Neurologica Taiwanica, Chen et al.(4) presented the inverse association between adherence of antithrombotic agents and poor outcomes after a first-ever ischemic stroke. The findings were consistent with Sung, et al.(5) that medication nonadherence are prevalent in young adu...
Source: Acta Neurologica Taiwanica - February 7, 2020 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Direct Oral Anticoagulants in Atrial Fibrillation Patients with Concomitant Hyperthyroidism.
CONCLUSION: Among NVAF Asian patients with concomitant hyperthyroidism, DOACs may be an effective and safer alternative to warfarin. Thromboprophylaxis with DOACs may be considered for such patients, and it is important to validate this finding in further prospective study. PMID: 32009154 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - February 3, 2020 Category: Endocrinology Authors: Chan YH, Wu LS, See LC, Liu JR, Chang SH, Chao TF, Yeh YH, Kuo CT, Lee HF, Lip GYH Tags: J Clin Endocrinol Metab Source Type: research

Acute Ischemic Stroke.
Authors: Rossi UG, Ierardi AM, Cariati M Abstract A 77-year-old woman with a history of hypertension developed acute onset of aphasia and right hemiplegia and hemisensory loss. She was urgently referred to emergency department. Cerebral multidetector computed tomographic angiography (MD-CTA) revealed an acute ischemic stroke due to the occlusion of the left middle cerebral artery (Figure 1). Since the symptoms started three hours previously, the patient was candidate for mechanical thrombectomy. The patient then performed a selective digital subtraction angiography (DSA) of the left internal carotid artery that con...
Source: Acta Neurologica Taiwanica - February 1, 2020 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Featured Review: Treating depression after stroke
Depression is common after stroke yet often is not detected or inadequately treated.Review authors from Australia, Canada, Taiwan and the UK asked, " Do pharmacological treatments, non ‐invasive brain stimulation, psychological treatments, or combination treatments reduce the proportion of people with depression or the extent of depressive symptoms after stroke? "The authors included trials that reported on the use of pharmacological, non ‐invasive brain stimulation, psychological, and combination therapy interventions to treat depression after stroke. Mean age of people included in the trials ranged from 54 to 78 year...
Source: Cochrane News and Events - January 28, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news

Cancers, Vol. 12, Pages 189: Influence of Baseline Cardiovascular Comorbidities on Mortality after Androgen Deprivation Therapy for Metastatic Prostate Cancer
ih Shao Few studies have assessed the benefits of androgen deprivation therapy (ADT) in men with metastatic prostate cancer (PC; mPC) at an old age or with major cardiovascular conditions. A retrospective cohort consisted of 3835 men with newly diagnosed mPC from the Taiwan Cancer Registry of 2008–2014. Among them, 2692 patients received only ADT in the first year after the cancer diagnosis, and 1143 patients were on watchful waiting. The inverse probability of treatment-weighted Cox model was used to estimate the effects of ADT on all-cause mortality and PC-specific mortality according to age, and the...
Source: Cancers - January 12, 2020 Category: Cancer & Oncology Authors: Wu Fang Hwang Shih Shao Tags: Article Source Type: research

Spatiotemporal assessment of mortality attributable to ambient PM 2.5 exposure in Taiwan during 2008 –2015
In this study, we quantified the spatiotemporal burden of mortality attributable to ambient fine particulate matter (PM2.5, which is defined as a mass of particles with an aerodynamic dry diameter of ≤ 2.5 μm) in Taiwan during 2008–2015. Hourly concentrations of PM2.5 were obtained from the Taiwan Air Quality Monitoring Network. According to geographical and climatic characteristics, the Taiwan Environmental Protection Administration has divided Taiwan into seven air quality regions (AQRs): the North (four districts), Chu-Miao (two districts), Central (three districts), Yun-Chia-Nan (three districts), Kao-Ping (two...
Source: Air Quality, Atmosphere and Health - January 4, 2020 Category: Environmental Health Source Type: research

Statins reduce new-onset atrial fibrillation after acute myocardial infarction: A nationwide study
The objective of this study was to investigate whether statins confer a beneficial effect on AF after AMI. Data available in the Taiwan National Health Insurance Research Database on 32886 AMI patients between 2008 and 2011 were retrospectively analyzed. Total 27553 (83.8%) had complete 1-yr follow-up data. Cardiovascular outcomes were analyzed based on the baseline characteristics and AF type (existing, new-onset, or non-AF). AF groups had significantly higher incidence of heart failure (HF), stroke, all-cause death, and major adverse cardiac and cerebrovascular event (MACCE) after index AMI (all P 
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Risk of ischemic stroke in patients with prostate cancer receiving androgen deprivation therapy in Taiwan
Androgen deprivation therapy (ADT) in the treatment of prostate cancer may be associated with an increased risk of thromboembolic disease. The aim of our study was to investigate the association of ADT in the ...
Source: BMC Cancer - December 30, 2019 Category: Cancer & Oncology Authors: Kuang-Ming Liao, Yaw-Bin Huang, Chung-Yu Chen and Chen-Chun Kuo Tags: Research article Source Type: research

A Case of Fabry Disease Presenting with Young Stroke and Fever.
Authors: Wu LC, Chiang CT, Lee KF Abstract Although it is known that Fabry disease should be included in the differential diagnosis of young stroke and fever of unknown origin, it has not been reported in the literature of stroke with fever as the presentation of Fabry disease. This is relevant because stroke with fever may misguide the differential diagnosis. Here we present a young stroke patient with fever. DWI of brain MRI revealed acute multiple infarctions. Due to the fever, infectious and inflammatory origins such as infective endocarditis and autoimmune diseases were examined first. However, we could not id...
Source: Acta Neurologica Taiwanica - December 25, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Adult onset MELAS Syndrome Presenting as A Mimic of Herpes Simplex Encephalitis.
CONCLUSION: The clinical presentation and imaging studies of MELAS in adults are variable and may mimic those of HSE. Antiviral therapy should be administered until the diagnosis of MELAS is definitive. Infection and metformin may have also precipitated MELAS manifestation in this patient. Clinicians should avoid potential mitochondrial-toxic drugs in these patients. PMID: 31867706 [PubMed - in process]
Source: Acta Neurologica Taiwanica - December 25, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Comparing the Effectiveness and Safety of Non-Vitamin K Antagonist Oral Anticoagulants and Warfarin in the Elderly Asian Patients with Atrial Fibrillation: A Nationwide Cohort Study.
CONCLUSIONS: Compared to warfarin, NOACs were associated with a significantly lower risk of adverse events, with heterogeneity in treatment effects among different age strata. Overall, the clear safety signal in favor of NOACs over warfarin was evident irrespective of age strata, being most marked in the most elderly. PMID: 31809694 [PubMed - as supplied by publisher]
Source: Chest - December 3, 2019 Category: Respiratory Medicine Authors: Chao TF, Chiang CE, Liao JN, Chen TJ, Lip GYH, Chen SA Tags: Chest Source Type: research

Acrolein is involved in ischemic stroke-induced neurotoxicity through spermidine/spermine-N1-acetyltransferase activation.
CONCLUSION: Overall, our current results demonstrate that acrolein is a culprit of neuronal damage through GSH depletion in stroke patients. The mechanism underlying the role of acrolein in stroke-related neuronal damage occurs through SSAT-induced polyamine oxidation by NF-kB pathway activation. These results provide a novel mechanism of neurotoxicity in stroke patients, aid in the development of neutralizing or preventive measures, and further our understanding of neural protection. PMID: 31629858 [PubMed - as supplied by publisher]
Source: Experimental Neurology - October 17, 2019 Category: Neurology Authors: Liu JH, Wang TW, Lin YY, Ho WC, Tsai HC, Chen SP, Lin AM, Liu TY, Wang HT Tags: Exp Neurol Source Type: research

IJERPH, Vol. 16, Pages 3491: The Relationship between Scabies and Stroke: A Population-Based Nationwide Study
Conclusions: The results of the study indicated an elevated risk of stroke among scabies patients, an association that might be contributed to by immunopathological factors. This information could serve as a reminder to clinicians to remain alert to any indications of neurological impairment in patients previously infected with scabies.
Source: International Journal of Environmental Research and Public Health - September 19, 2019 Category: Environmental Health Authors: Meng-Huan Wu Chien-Yu Li Huichin Pan Yu-Chieh Lin Tags: Article Source Type: research

IJERPH, Vol. 16, Pages 3472: Exploration of Medical Trajectories of Stroke Patients Based on Group-Based Trajectory Modeling
In this study, we used group-based trajectory modeling (GBTM) to study the characteristics of various groups of patients hospitalized with ACVD. In this research, the patient data were derived from the 1 million sampled cases in the National Health Insurance Research Database (NHIRD) in Taiwan. Cases who had been admitted to hospitals fewer than four times or more than eight times were excluded. Characteristics of the ACVD patients were collected, including age, mortality rate, medical expenditure, and length of hospital stay for each admission. We then performed GBTM to examine hospitalization patterns in patients who had...
Source: International Journal of Environmental Research and Public Health - September 18, 2019 Category: Environmental Health Authors: Ting-Ying Chien Mei-Lien Lee Wan-Ling Wu Hsien-Wei Ting Tags: Article Source Type: research

Accelerated Risk of Premature Ischemic Stroke in 5‐Year Survivors of Nasopharyngeal Carcinoma
Conclusion.Not only was the stroke risk in NPC survivors higher than that in the general population, but the onset age was also 10 years earlier. Future survivorship care should include ischemic stroke as a late complication, for its proper prevention and management.Implications for Practice.Nasopharyngeal carcinoma (NPC) is endemic in Taiwan, and its 5‐year survival is 65.2%. With the increased 5‐year cancer survivors, survivorship has become an important issue. However, research on NPC survivorship is very rare. To the authors’ knowledge, this is the first population‐based study on long‐term NPC survivors. This...
Source: The Oncologist - September 11, 2019 Category: Cancer & Oncology Authors: Min-Chi Chen, Feng-Che Kuan, Shiang-Fu Huang, Chang-Hsien Lu, Ping-Tsung Chen, Cih-En Huang, Ting-Yao Wang, Chih-Cheng Chen, Kuan-Der Lee Tags: Head and Neck Cancers, Health Outcomes and Economics of Cancer Care Source Type: research

Nephrotic Syndrome is Associated with Increased Risk of Ischemic Stroke
Background: To determine if the nephrotic syndrome (NS) is an independent risk factor of ischemic stroke. Methods: This is a retrospective nationwide cohort study through an analysis of the National Health Insurance Research Database in Taiwan. To evaluate the risk of stroke, the corresponding controls were selected at a 4:1 ratio in the number of subjects, and they were matched with the study group in age, gender, Charlson comorbidity index (CCI), and index date. Results: From a total of 16,245 surveyed subjects, ischemic stroke occurred in 1235 (7.6%) and hemorrhagic stroke in 129 (.74%) of them.
Source: Journal of Stroke and Cerebrovascular Diseases - August 16, 2019 Category: Neurology Authors: Jin-An Huang, Ching-Heng Lin, Yao-Tien Chang, Cheng-Ting Lee, Ming-Ju Wu Source Type: research

Impact Of Sirt6 And Sirt7 Genetic Polymorphisms On Risk Of Early-Onset Ischemic Stroke
Background and Aims: SIRT6 and SIRT7 have been implicated in the repression of inflammation, oxidative stress, and aging. Polymorphisms in SIRT6 and SIRT7 may be important for increasing carotid plaque burden and promoting atherosclerosis. The aim of this study was to investigate the association of SIRT6 and SIRT7 genetic polymorphisms with risk of early-onset ischemic stroke in Taiwan.
Source: Atherosclerosis - August 5, 2019 Category: Cardiology Authors: F.I. Hsieh, J.Y. Huang, H.Y. Chiou, L. Li-Ming, J.S. Jeng, H.J. Lin, C.J. Hu Tags: Posters 26 - 29 May, 2019 Source Type: research

Significant Associations Of Nrf1 Genetic Polymorphisms With The Risk Of Early-Onset Ischemic Stroke
In this study, we aim to investigate the relationship between the genetic polymorphisms of NRF1 and the risk of early-onset ischemic stroke in Taiwan.
Source: Atherosclerosis - August 5, 2019 Category: Cardiology Authors: J.Y. Huang, H.Y. Chiou, L.M. Lien, J.S. Jeng, H.J. Lin, C.J. Hu, F.I. Hsieh Tags: Posters 26 - 29 May, 2019 Source Type: research

Use of Chinese herbal medicines by rheumatoid arthritis patients was associated with lower risk of stroke: A retrospective cohort study.
CONCLUSION: The CHMs use was associated with lower risk of stroke for RA patients, suggesting that it could be integrated into conventional therapy to prevent subsequent stroke incident. PMID: 31331548 [PubMed - in process]
Source: Complementary Therapies in Medicine - July 25, 2019 Category: Complementary Medicine Authors: Lai NS, Livneh H, Fan YH, Lu MC, Liao HH, Tsai TY Tags: Complement Ther Med Source Type: research

Adjunctive statin therapy reduces intracranial hemorrhage and 1-year mortality in patients with atrial fibrillation after acute ischemic stroke: A population-based epidemiological study from Taiwan
ConclusionsStatin therapy reduced the risk of ICH and 1-year mortality in AF patients who experienced acute ischemic stroke.
Source: Journal of Clinical Neuroscience - July 20, 2019 Category: Neuroscience Source Type: research

Renal Function Estimates and Dosing of Direct Oral Anticoagulants in Stroke Patients with Atrial Fibrillation: An Observational Study.
CONCLUSION: Although substituting eGFR for CrCl carries potential risks of DOAC overdosing in patients with AF, the effect might be offset by clinicians' predilection for lower dosage in this stroke cohort. PMID: 31304571 [PubMed - in process]
Source: Acta Neurologica Taiwanica - July 17, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Potential benefits of biologics on stroke and mortality in patients with rheumatoid arthritis: A nationwide population ‐based cohort study in Taiwan
ConclusionBiologics used in RA patients have been shown to have a beneficial impact on improving clinical outcomes, including decreased risks of death and stroke. The economic burden from costs of biologics may be alleviated by improving outcomes.
Source: International Journal of Rheumatic Diseases - June 25, 2019 Category: Rheumatology Authors: Chao ‐Hsiun Tang, Fun Yu, Ching‐Ya Huang, Der‐Yuan Chen Tags: ORIGINAL ARTICLE Source Type: research

IJERPH, Vol. 16, Pages 2228: Effect of an Oral Health Programme on Oral Health, Oral Intake, and Nutrition in Patients with Stroke and Dysphagia in Taiwan: A Randomised Controlled Trial
ang Huang No previous studies have evaluated an oral health programme, before swallowing therapy, in patients with stroke and dysphagia in Taiwan. This randomised controlled trial evaluated the effect of an oral health programme (i.e., sputum assessment, Bass method-based tooth brushing, and tooth coating with fluoride toothpaste) before swallowing therapy. Sixty-six patients with stroke (23 female, 43 male) in our rehabilitation ward, who underwent nasogastric tube insertion, were assigned randomly to an oral care group (n = 33) and a control group (n = 33). Demographic data, oral health assessment, Functional Oral...
Source: International Journal of Environmental Research and Public Health - June 24, 2019 Category: Environmental Health Authors: Chen Chen Chen Lee Chang Huang Tags: Article Source Type: research

Central venous catheter use increases ischemic stroke risk: a nationwide population-based study
ConclusionCVC placement increases ischemic stroke risk, particularly in those aged ≤35 years; this trend warrants further investigation.
Source: QJM - June 21, 2019 Category: Internal Medicine Source Type: research

Cardiovascular outcomes of vildagliptin in patients with type  2 diabetes mellitus after acute coronary syndrome or acute ischemic stroke
ConclusionsAmong patients with type  2 diabetes mellitus after a recent acute coronary syndrome or acute ischemic stroke, treatment with vildagliptin was not associated with increased risks of CV death, non‐fatal myocardial infarction, non‐fatal stroke and hospitalization for HF.
Source: Journal of Diabetes Investigation - June 17, 2019 Category: Endocrinology Authors: Dong ‐Yi Chen, Yan‐Rong Li, Chun‐Tai Mao, Chi‐Nan Tseng, I‐Chang Hsieh, Ming‐Jui Hung, Pao‐Hsien Chu, Chao‐Hung Wang, Ming‐Shien Wen, Wen‐Jin Cherng, Tien‐Hsing Chen Tags: Original Article Source Type: research

Prediction of acute coronary syndrome, ischemic stroke, and mortality in patients with heart failure: a comparison of CHA 2 DS 2 -VASc and AHEAD scores
ConclusionsThe ability of the CHA2DS2-VASc score to predict macrovascular complications (ACS and IS) in HF patients was higher than that of AHEAD.
Source: Journal of Interventional Cardiac Electrophysiology - June 14, 2019 Category: Cardiology Source Type: research

Gall bladder surgery lowers stroke risk more than gallstone removal
Gall bladder removal could lower cardiovascular disease risk -- and stroke risk, as a result -- for gallstone patients, report researchers in Taiwan.
Source: Health News - UPI.com - June 5, 2019 Category: Consumer Health News Source Type: news

A functional recovery profile for patients with stroke following post-acute rehabilitation care in Taiwan
ConclusionsThis study showed that the PAC rehabilitation unit was beneficial for patients with acute stroke who had functional impairments. The study results may call for further investigation to identify and develop better models for the delivery of rehabilitation in the stroke PAC unit.
Source: Journal of the Formosan Medical Association - May 29, 2019 Category: General Medicine Source Type: research

A functional recovery profile for patients with stroke following post-acute rehabilitation care in Taiwan.
CONCLUSIONS: This study showed that the PAC rehabilitation unit was beneficial for patients with acute stroke who had functional impairments. The study results may call for further investigation to identify and develop better models for the delivery of rehabilitation in the stroke PAC unit. PMID: 31147198 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - May 27, 2019 Category: General Medicine Authors: Chien SH, Sung PY, Liao WL, Tsai SW Tags: J Formos Med Assoc Source Type: research

Cardiovascular Outcomes of Vildagliptin in Patients with Type 2 Diabetes Mellitus after Acute Coronary Syndrome or Acute Ischemic Stroke
ConclusionsAmong patients with T2DM after a recent ACS or AIS, treatment with vildagliptin was not associated with increased risks of CV death, nonfatal MI, nonfatal stroke, and hospitalization for HF.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - May 22, 2019 Category: Endocrinology Authors: Dong ‐Yi Chen, Yan‐Rong Li, Chun‐Tai Mao, Chi‐Nan Tseng, I‐Chang Hsieh, Ming‐Jui Hung, Pao‐Hsien Chu, Chao‐Hung Wang, Ming‐Shien Wen, Wen‐Jin Cherng, Tien‐Hsing Chen Tags: Original Article Source Type: research

Acupuncture treatment and the risk of urinary tract infection in stroke patients: a nationwide matched cohort study.
CONCLUSIONS: In this nationwide retrospective cohort study, we raised the possibility that acupuncture treatment may be associated with a reduced risk of UTI among stroke patients. However, the protective effect associated with acupuncture treatment requires further validation using randomized clinical trials. PMID: 31032620 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - April 29, 2019 Category: Complementary Medicine Authors: Yang JL, Chen TL, Yeh CC, Hu CJ, Liao CC, Lane HL, Shih CC Tags: Acupunct Med Source Type: research

A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia
In conclusion, our data support that plasma DAO levels were increased in PSD patients and correlated with brain WMH, independent of age, gender, hypertension, and renal function. Plasma DAO levels may therefore aid in PSD diagnosis. Introduction Stroke is a risk factor for both vascular dementia and Alzheimer's disease (1, 2). Functional recovery develops over the course of 26 weeks after a stroke (3), but the survivors are often left with disabilities. In addition to the sequelae of acute neuronal damage, the 1-year post-stroke dementia (PSD) rates after first-ever and recurrent stroke are ~10 and 30...
Source: Frontiers in Neurology - April 26, 2019 Category: Neurology Source Type: research

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - April 26, 2019 Category: Neurology Source Type: research

The Mortality and the Risk of Aspiration Pneumonia Related with Dysphagia in Stroke Patients
Background: Dysphagia may result in poor outcomes in stroke patients due to aspiration pneumonia and malnutrition. Goal: The aim of the study was to investigate aspiration pneumonia and the mortality rate in stroke patients with dysphagia in Taiwan. Methods: We selected 1220 stroke patients, divided them into dysphagia and nondysphagia groups, and matched them according to age; covariates and comediations from 2000 to 2005 were identified from the NHIRD 2000 database. The date of the diagnosed stroke for each patient was defined as the index date.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2019 Category: Neurology Authors: Ming-Chu Feng, Yi-Ching Lin, Yu-Han Chang, Chun-Hung Chen, Hsiu-Chu Chiang, Ling-Chun Huang, Yuan-Han Yang, Chih-Hsing Hung Source Type: research

Intravenous Thrombolysis in Acute Ischemic Stroke After Idarucizumab Reversal of Dabigatran Effect: Analysis of the Cases From Taiwan
Background: Asians with atrial fibrillation carry a higher risk of ischemic stroke than non-Asians even under treatment of nonvitamin K antagonist oral anticoagulants. The purpose of the study was to observe the feasibility of intravenous thrombolytic therapy after administering a reversal agent, idarucizumab, in dabigatran-treated patients with acute ischemic stroke in Taiwan. Methods: Dabigatran-treated patients with acute ischemic stroke who received intravenous recombinant tissue plasminogen activator (rt-PA) after idarucizumab reversal were enrolled in the retrospective nationwide study.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2018 Category: Neurology Authors: Chen-Wen Fang, Yi-Te Tsai, Ping-Chen Chou, Hsi-Ming Chen, Chien-Ming Lu, Chen-Rong Tsao, Chih-Lin Chen, Mu-Chien Sun, Yu-Song Shih, Cheng-Yang Hsieh, Lu-An Chen, Po-Lin Chen, Jung-Tze Yeh, Yi-Heng Li Source Type: research

Renal dysfunction increases the risk of recurrent stroke in patients with acute ischemic stroke
This study investigated risks of short-term (1 and 3 months) and long-term (1-year) recurrent stroke associated with glomerular filtration rate (eGFR) in patients with acute ischemic stroke.
Source: Atherosclerosis - July 27, 2018 Category: Cardiology Authors: I-Kuan Wang, Li-Ming Lien, Jiunn-Tay Lee, Chung-Hsiang Liu, Chih-Hung Chen, Ching-Huang Lin, Jiann-Shing Jeng, Chaur-Jong Hu, Tzung-Hai Yen, Sien-Tsong Chen, Hou-Chang Chiu, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research

Stroke 112 Brief Report
Conclusions—Stroke 112, a universal stroke educational program without language barriers was developed. It could potentially be implemented worldwide, especially where 112 is used as an emergency phone number.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jing Zhao, Maryellen F. Eckenhoff, Wei-Zen Sun, Renyu Liu Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

The predictive role of CHA2DS2–VASc score between venous thromboembolism and ischemic stroke: a large-scale cohort study
Conclusion: Our study is the first to concern the performance of CHA2DS2–VASc score in predicting the risk of ischemic stroke in VTE patients and the risk of VTE in ischemic stroke patients. Nevertheless, the performance of the score was modest, and the transportability of the score in these populations still needs to be defined.
Source: Journal of Hypertension - February 2, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Patients with Cerebral Stroke Have an Increased Risk of Gastroesophageal Reflux Disease: A Population-Based Cohort Study
This study was designed to investigate the prevalence and risk of gastroesophageal reflux disease (GERD) between patients with stroke and those without stroke in Taiwan.
Source: Journal of Stroke and Cerebrovascular Diseases - January 8, 2018 Category: Neurology Authors: Chen-Shu Chang, Hsuan-Ju Chen, Chun-Hui Liao Source Type: research

Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke
This study aimed to evaluate the impact of admission estimated glomerular filtration rate (eGFR) levels on short-term (1-month) and long-term (1-year) mortality in patients with acute ischemic stroke.
Source: Atherosclerosis - December 11, 2017 Category: Cardiology Authors: I-Kuan Wang, Chung-Hsiang Liu, Tzung-Hai Yen, Jiann-Shing Jeng, Sheng-Feng Sung, Pai-Hao Huang, Jie-Yuan Li, Yu Sun, Cheng-Yu Wei, Li-Ming Lien, I-Ju Tsai, Fung-Chang Sung, Chung Y. Hsu, Taiwan Stroke Registry Investigators Source Type: research

The effect and associated factors of dispatcher recognition of stroke: A retrospective observational study.
CONCLUSIONS: The dispatchers should spend more time identifying stroke patients by following the dispatch protocol. Recognition of stroke by dispatchers was associated with improved stroke care. PMID: 29158105 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - November 17, 2017 Category: General Medicine Authors: Hsieh MJ, Chien KL, Sun JT, Tang SC, Tsai LK, Chiang WC, Chien YC, Jeng JS, Huei-Ming Ma M, Taipei EMS Stroke Collaborative Group Tags: J Formos Med Assoc Source Type: research

Functional Outcomes, Subsequent Healthcare Utilization, and Mortality of Stroke Postacute Care Patients in Taiwan: A Nationwide Propensity Score-matched Study
To evaluate the benefits of the national stroke postacute care (PAC) program on clinical outcomes and subsequent healthcare utilization.
Source: Journal of the American Medical Directors Association - August 10, 2017 Category: Health Management Authors: Li-Ning Peng, Wan-Hsuan Lu, Chih-Kuang Liang, Ming-Yueh Chou, Chih-Ping Chung, Shu-Ling Tsai, Zhi-Jun Chen, Fei-Yuan Hsiao, Liang-Kung Chen, Taiwan Stroke Postacute Care (PAC) Study Group Tags: Original Study Source Type: research

Recent advances of stroke thrombolysis in  Taiwan: A successful interaction between physicians, regulators, and National Health Insurance Administration.
Recent advances of stroke thrombolysis in Taiwan: A successful interaction between physicians, regulators, and National Health Insurance Administration. J Formos Med Assoc. 2017 Jan 12;: Authors: Hsieh CY, Lin RT, Hu HH, Taiwan Stroke Society PMID: 28089493 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - January 12, 2017 Category: Journals (General) Authors: Hsieh CY, Lin RT, Hu HH, Taiwan Stroke Society Tags: J Formos Med Assoc Source Type: research