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IJERPH, Vol. 18, Pages 10034: Responsiveness of the Spanish Version of Newcastle Stroke-Specific Quality of Life Measure (NEWSQOL)
Conclusion: The Spanish version of NEWSQOL shows between marked and mild responsiveness to measure the perception of QoL in post-stroke patients. Therefore, its use can be suitable for evaluation studies, clinical trials and clinical practice.
Source: International Journal of Environmental Research and Public Health - September 24, 2021 Category: Environmental Health Authors: Concepci ón Soto-Vidal Victoria Calvo-Fuente Alfonso Muriel-Garc ía Tom ás Gallego-Izquierdo Carlos Gonz ález-Alted Soraya Pacheco-da-Costa Tags: Article Source Type: research

Prognostic value of balance performance for improvements of community ambulation among stroke patients: a cohort study
CONCLUSIONS: Semi-tandem and the 5STS tests can discriminate patients who improve level of functional ambulation and predict transition times within three months in nonambulators and limited community ambulation patients, respectively.CLINICAL REHABILITATION IMPACT: The semi-tandem and the 5STS tests can be performed easily in clinical settings to predict improvement of functional ambulation level in patients following stroke.PMID:34498829 | DOI:10.23736/S1973-9087.21.06996-3
Source: European Journal of Physical and Rehabilitation Medicine - September 9, 2021 Category: Rehabilitation Authors: Francesc Medina-Mirapeix M Jos é Crisostomo Rodrigo Mart ín San Agustín M Piedad S ánchez-Martínez Source Type: research

A case-control analysis of stroke in Covid-19 patients: Results of Unusual Manifestations of Covid-19-Study 11
CONCLUSIONS: The incidence of stroke in COVID-19 patients presenting to EDs was lower than in the non-COVID-19 reference sample. COVID-19 patients with stroke had greater need for hospitalization and ICU admission than those without stroke, and longer hospitalization and greater in-hospital mortality than non-COVID-19 patients with stroke.PMID:34490961 | DOI:10.1111/acem.14389
Source: Accident and Emergency Nursing - September 7, 2021 Category: Emergency Medicine Authors: Eric Jorge Garc ía-Lamberechts Òscar Miró Marcos Fragiel Pere Llorens S ònia Jiménez Pascual Pi ñera Guillermo Burillo Alfonso Mart ín Francisco Javier Mart ín-Sánchez Javier Jacob Aitor Alqu ézar-Arbé Laura Ejarque Mart ínez Bel én Rodrígue Source Type: research

IJERPH, Vol. 18, Pages 9348: Systolic Blood Pressure and Outcomes in Stable Outpatients with Recent Symptomatic Artery Disease: A Population-Based Longitudinal Study
Conclusions: In this real-world cohort of symptomatic arterial disease patients, most of whom are not eligible for clinical trials, the risk of subsequent events and death varies according to the levels of SBP and the location of previous events. Especially among patients with large artery atherosclerosis, PAD or CVD, SBP <130 mm Hg may result in increased mortality. Due to potential factors in this issue, Prospective, well designed studies are warranted to confirm these observational data.
Source: International Journal of Environmental Research and Public Health - September 4, 2021 Category: Environmental Health Authors: Juan F. S ánchez Muñoz-Torrero Guillermo Escudero-S ánchez Juli án F. Calderón-García Sergio Rico-Mart ín Nicol ás Roberto Robles M. Asunci ón Bacaicoa Jos é N. Alcalá-Pedrajas Guadalupe Gil-Fern ández Manuel Monreal on behalf of the FRENA Inv Tags: Article Source Type: research

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

Global research trends in COVID-19 with MRI and PET/CT: a scoping review with bibliometric and network analyses
ConclusionCOVID-19 pandemic is still spreading worldwide, and the knowledge about its different facets continues advancing. MRI and PET/CT are being used in more than 50% of the selected studies; research trends span seven categories, no only the diagnostic but others like socio-economic impact and pathogenesis Developed countries had an advantage by having hospitals with more resources, including MRI and PET/CT facilities in the same institution to supplement basic assessment in patients with COVID-19.
Source: Clinical and Translational Imaging - August 14, 2021 Category: Radiology Source Type: research

Relationship between multimorbidity and outcomes in atrial fibrillation
CONCLUSIONS: In a nationwide contemporary cohort of AF anticoagulated patients, multimorbidity was inversely associated with good anticoagulation control. A progressively higher risk for major bleeding, CV death and all-cause death was found across CCI quartiles.PMID:34303775 | DOI:10.1016/j.exger.2021.111482
Source: Experimental Gerontology - July 25, 2021 Category: Geriatrics Authors: Marco Proietti Mar ía Asunción Esteve-Pastor Jos é Miguel Rivera-Caravaca Vanessa Rold án Inmaculada Rold án Rabadán Javier Mu ñiz Ángel Cequier Vicente Bertomeu-Mart ínez Lina Badim ón Manuel Anguita Gregory Y H Lip Francisco Mar ín FANTASIIA Source Type: research

DNA methylation analyses identify an intronic < i > ZDHHC6 < /i > locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
by Nicole M. Davis Armstrong, Wei-Min Chen, Fang-Chi Hsu, Michael S. Brewer, Natalia Cullell, Israel Fern ández-Cadenas, Stephen R. Williams, Michèle M. Sale, Bradford B. Worrall, Keith L. Keene Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study was to identify methylation loci associated with the time to recurrent cerebr o- and cardiovascular events in individuals of European and African descent. DNA methylation profiles were generated for 180 individu...
Source: PLoS One - July 12, 2021 Category: Biomedical Science Authors: Nicole M. Davis Armstrong Source Type: research

IJERPH, Vol. 18, Pages 6615: The Effectiveness of Additional Core Stability Exercises in Improving Dynamic Sitting Balance, Gait and Functional Rehabilitation for Subacute Stroke Patients (CORE-Trial): Study Protocol for a Randomized Controlled Trial
rútia Background: Trunk impairment produces disorders of motor control, balance and gait. Core stability exercises (CSE) are a good strategy to improve local strength of trunk, balance and gait. Methods and analysis: This is a single-blind multicenter randomized controlled trial. Two parallel groups are compared, and both perform the same type of therapy. A control group (CG) (n = 110) performs conventional physiotherapy (CP) (1 h per session) focused on improving balance. An experimental group (EG) (n = 110) performs CSE (30 min) in addition to CP (30 min) (1 h/session in total). EG is divided in two subgroups, in wh...
Source: International Journal of Environmental Research and Public Health - June 19, 2021 Category: Environmental Health Authors: Rosa Cabanas-Vald és L ídia Boix-Sala Montserrat Grau-Pellicer Juan Antonio Guzm án-Bernal Fernanda Maria Caballero-G ómez Gerard Urr útia Tags: Article Source Type: research

Acute Stroke Care during the COVID-19 Pandemic: Reduction in the Number of Admissions of Elderly Patients and Increase in Prehospital Delays
Conclusion: We observed a reduction in the number of acute strokes and TIAs admitted during the COVID-19 period. This drop affected especially elderly patients, and despite a delay in their arrival to the emergency department, the proportion of patients treated with recanalization therapies was preserved.Cerebrovasc Dis
Source: Cerebrovascular Diseases - March 17, 2021 Category: Neurology Source Type: research

IJERPH, Vol. 18, Pages 2810: Effects of Virtual Reality-Based Therapy on Quality of Life of Patients with Subacute Stroke: A Three-Month Follow-Up Randomized Controlled Trial
Conclusion: The conventional rehabilitative approach combined with virtual reality appears to be more effective for improving the perceived health-related quality of life in stroke survivors.
Source: International Journal of Environmental Research and Public Health - March 10, 2021 Category: Environmental Health Authors: Rodr íguez-Hernández Criado- Álvarez Corregidor-S ánchez Mart ín-Conty Mohedano-Moriano Polonio-L ópez Tags: Article Source Type: research

Stroke prevention in patients with type 2 diabetes mellitus or prediabetes: recommendations of the Spanish Society of Neurology’s Stroke Study Group
Publication date: Available online 6 March 2021Source: Neurología (English Edition)Author(s): B. Fuentes, S. Amaro, M. Alonso de Leciñana, J.F. Arenillas, O. Ayo-Martín, M. Castellanos, M. Freijo, García-Pastor, M. Gomis, M. Gómez Choco, E. López-Cancio, P. Martínez Sánchez, A. Morales, E.J. Palacio-Portilla, M. Rodríguez-Yáñez, J. Roquer, T. Segura, J. Serena, J. Vivancos-Mora, A d hoc committee of the Spanish Society of Neurology’s Stroke Study Group.
Source: Neurologia - March 6, 2021 Category: Neurology Source Type: research

Impact of prescription patterns of antithrombotic treatment on atrial fibrillation-related ischemic stroke.
CONCLUSIONS: The prescription of oral anticoagulants, particularly direct oral anticoagulants, has increased from 2013 to 2019 in our Health Assistance Area. This increase might partially explain the reduction in AF-related IS. PMID: 33326304 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - December 18, 2020 Category: Research Tags: Curr Med Res Opin Source Type: research

Stroke Knowledge in the EstEPA Project, a Population-Based Study
Stroke knowledge is poor in the general population worldwide. Yet, data from Spanish-Speaking populations, particularly in Latin America, are scant. We aim to evaluate stroke awareness using personal interviews in a population-based study.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2020 Category: Neurology Authors: Maximiliano A Hawkes, Maia M Gomez-Schneider, Daiana E Dossi, Mario O Melcon, Sebasti án F Ameriso Source Type: research

Fried-Food Consumption Does Not Increase the Risk of Stroke in the Spanish Cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC) Study
ConclusionsIn this Spanish cohort, whose participants mainly used olive oil or sunflower oil when frying, the consumption of fried food was not associated with an increased risk of incident stroke.
Source: Journal of Nutrition - September 16, 2020 Category: Nutrition Source Type: research

IJERPH, Vol. 17, Pages 6014: Coping Strategies, Quality of Life, and Neurological Outcome in Patients Treated with Mechanical Thrombectomy after an Acute Ischemic Stroke
er-Soler New reperfusion therapies have improved the clinical recovery rates of acute ischemic stroke patients (AISP), but it is not known whether other factors, such as the ability to cope, might also have an effect. The aim of this study was to evaluate the effect of endovascular treatment (EVT) on coping strategies, quality of life, and neurological and functional outcomes in AISP at 3 months and 1 year post-stroke. A multicenter, prospective, longitudinal, and comparative study of a sub-study of the participants in the Endovascular Revascularization with Solitaire Device versus Best Medical Therapy in Anterior Cir...
Source: International Journal of Environmental Research and Public Health - August 18, 2020 Category: Environmental Health Authors: Silvia Revert é-Villarroya Antoni D ávalos S ílvia Font-Mayolas Marta Berenguer-Poblet Esther Sauras-Col ón Carlos L ópez-Pablo Estela Sanjuan-Men éndez Luc ía Muñoz-Narbona Rosa Su ñer-Soler Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 4237: Validation of the Spanish Version of Newcastle Stroke-Specific Quality of Life Measure (NEWSQOL)
Conclusion: The Spanish version of the NEWSQOL questionnaire is reliable, valid, and feasible to evaluate quality of life in the Spanish population.
Source: International Journal of Environmental Research and Public Health - June 13, 2020 Category: Environmental Health Authors: Concepci ón Soto-Vidal Soraya Pacheco-da-Costa Victoria Calvo-Fuente Sara Fern ández-Guinea Carlos Gonz ález-Alted Tom ás Gallego-Izquierdo Tags: Article Source Type: research

Concern as heart attack and stroke patients delay seeking help
Consultants report drop in admissions of people with non-coronavirus related conditionsCoronavirus – latest updatesSee all our coronavirus coverageFurther evidence is emerging of dramatic falls in numbers of hospital patients presenting with serious medical conditions such as strokes and heart attacks since the beginning of the coronavirus pandemic.AUS study found that interventions for serious heart attacks have fallen 38% since 1 March. Similar reductions were reported in Spain, while inLombardy, the worst affected region of Italy, the figure was 70%.Continue reading...
Source: Guardian Unlimited Science - April 16, 2020 Category: Science Authors: Laura Spinney Tags: Coronavirus outbreak Hospitals Doctors Health Medical research Science Society Heart disease Heart attack Stroke World news UK news Source Type: news

Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial
Publication date: March 2020Source: The Lancet Neurology, Volume 19, Issue 3Author(s): Hugues Chabriat, Claudio L Bassetti, Ute Marx, Marie-Laure Audoli-Inthavong, Aurore Sors, Estelle Lambert, Marine Wattez, Dirk M Hermann, Katharina ALTHAUS, Sergi AMARO, Hee-Joon BAE, Zbigniew BAK, Leonardo BARBARINI, Pietro BASSI, Rodrigo BAZAN, Daniel BERECZKI, Tomasz BERKOWICZ, Joerg BERROUSCHOT, Dylan BLACQUIERE, Waldemar BROLASummaryBackgroundS44819, a selective GABAA α5 receptor antagonist, reduces tonic post-ischaemic inhibition of the peri-infarct cortex. S44819 improved stroke recovery in rodents and increased cortical excitabi...
Source: The Lancet Neurology - February 19, 2020 Category: Neurology Source Type: research

AHA News: Spanish-Speaking Stroke Survivors Face More Obstacles
FRIDAY, Feb. 14, 2020 (American Heart Association News) -- Stroke survivors who speak Spanish are more likely to have low stroke literacy and a negative perception of their health care, according to a new study that called for breaking down language...
Source: Drugs.com - Daily MedNews - February 14, 2020 Category: General Medicine Source Type: news

Blood pressure drugs work far better if taken at night, study shows
‘Chronotherapy’ benefits of bedtime doses discovered in huge trialTaking blood pressure medication at bedtime rather than on waking halves the risk of events such as heart attack and stroke, a major study has revealed.Experts say the findings could potentially transform the way such medications are prescribed, but questions remain, not least why taking the medication at night has such a profound effect.Continue reading...
Source: Guardian Unlimited Science - October 22, 2019 Category: Science Authors: Nicola Davis Tags: Heart disease Society Heart attack Medical research Science Spain Stroke Source Type: news

Reducing Hypertension in a Post-Stroke Black and Hispanic Homecare Population: Results of a Pragmatic Randomized Controlled Trial.
CONCLUSION: The significant across-the-board SBP decreases suggest that UHC nurse/patient/physician interactions were the central component of SBP reduction and that additional efforts to lower recurrent stroke risk should test incremental improvements in usual care, not resource-intensive transitional care interventions. They also suggest the potential value of pragmatic homecare programs as part of a broader strategy to overcome HTN treatment barriers and improve secondary stroke prevention globally. PMID: 31541606 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - September 20, 2019 Category: Cardiology Authors: Feldman PH, McDonald MV, Trachtenberg M, Trifilio M, Onorato N, Sridharan S, Silver S, Eimicke J, Teresi J Tags: Am J Hypertens Source Type: research

Effects of virtual reality on balance and gait in stroke: a systematic review and meta-analysis.
CONCLUSION: The results show the potential benefit of virtual reality interventions to recover balance and gait after stroke. PMID: 31497866 [PubMed - in process]
Source: Revista de Neurologia - September 10, 2019 Category: Neurology Authors: Dominguez-Tellez P, Moral-Munoz JA, Casado-Fernandez E, Salazar A, Lucena-Anton D Tags: Rev Neurol Source Type: research

Motor imagery as a complementary technique for functional recovery after stroke: a systematic review.
Conclusions: The use of MI combined with conventional rehabilitation is an effective method for the recovery of functionality after stroke. Due to the great heterogeneity in the scientific literature available, new lines of research are necessary, in order to include well-designed studies of good methodological quality and to establish a consensus regarding the most appropriate protocols. PMID: 31347992 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - July 25, 2019 Category: Neurology Authors: López ND, Monge Pereira E, Centeno EJ, Miangolarra Page JC Tags: Top Stroke Rehabil Source Type: research

Patient characteristics and stroke and bleeding events in nonvalvular atrial fibrillation patients treated with apixaban and vitamin K antagonists: a Spanish real-world study.
Conclusion: Patients prescribed apixaban for the treatment of nonvalvular atrial fibrillation had lower rates of thromboembolic events and minor/major bleeding than patients on acenocoumarol. PMID: 31333045 [PubMed - as supplied by publisher]
Source: Journal of Comparative Effectiveness Research - July 25, 2019 Category: General Medicine Tags: J Comp Eff Res Source Type: research

Trajectories of memory, language, and visuoperceptual problems in people with stroke during the first year and controls in Colombia.
Conclusion: These findings suggest profound disparities in post-stroke cognitive functioning in Colombia compared to other more developed global region and underscore the importance of comprehensive cognitive rehabilitation services for individuals with stroke in Colombia and other similar global regions. Implications for rehabilitation Because this study found only negligible cognitive improvements beyond practice effects over the first year after stroke in Colombia among individuals without access to acute rehabilitation, it is imperative that comprehensive cognitive rehabilitation services be implemented immediately dur...
Source: Disability and Rehabilitation - June 4, 2019 Category: Rehabilitation Authors: Olabarrieta-Landa L, Pugh M, Calderón Chagualá A, Perrin PB, Arango-Lasprilla JC Tags: Disabil Rehabil Source Type: research

Biometric analysis of the Spanish studies on neurorehabilitation in cases of stroke indexed in Medline (2008-2017).
PMID: 31132140 [PubMed - in process]
Source: Revista de Neurologia - May 29, 2019 Category: Neurology Authors: Torres-Pascual C, Rodriguez-Rodriguez A, Serena-Leal J Tags: Rev Neurol Source Type: research

Structural Equation Model (SEM) of Stroke Mortality in Spanish Inpatient Hospital Settings: The Role of Individual and Contextual Factors
Conclusion. Contextual variables, and specifically the availability of stroke units, make a positive impact on individual variables that affect prognosis and mortality in ischemic stroke. Moreover, the determination of this impact is feasible through the use of structural equation methodology. We analyze the methodological and clinical implications of this type of study for hospital policies. Key words: Stroke; mortality; structural equation model; predictive model
Source: Frontiers in Neurology - May 16, 2019 Category: Neurology Source Type: research

Age- and Sex-Specific Risk Profiles and In-Hospital Mortality in 13,932 Spanish Stroke Patients
Conclusion: Although most of our findings were consistent with previous studies, it is important to take into account and highlight differences in in-hospital mortality between the sex and age group. Not to account for age-related differences between the sexes can give false results that may mislead management decisions. As most deaths in women were related to stroke, it is important to improve their early management, stroke code activation, access to stroke units and/or revascularisation therapies, especially in the older age groups.Cerebrovasc Dis
Source: Cerebrovascular Diseases - May 5, 2019 Category: Neurology Source Type: research

Clinical Improvement Following Stroke Promptly Reverses Post-stroke Cellular Immune Alterations
Conclusions: SIIA are detectable on admission of acute stroke patients. While it was assumed that post-stroke immunosuppression is rapidly reversed with improvement this is the first data set that shows that improvement actually is associated with a rapid reversal of SIIA demonstrating that SIIA require a constant signal to persist. The observation that HMGB-1 serum concentrations were similar in improved and non-improved cohorts argues against a role for this pro-inflammatory mediator in the maintenance of SIIA. Serum miRNA observed to be regulated in stroke in other publications was counter regulated with improvement in ...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia
In conclusion, our data support that plasma DAO levels were increased in PSD patients and correlated with brain WMH, independent of age, gender, hypertension, and renal function. Plasma DAO levels may therefore aid in PSD diagnosis. Introduction Stroke is a risk factor for both vascular dementia and Alzheimer's disease (1, 2). Functional recovery develops over the course of 26 weeks after a stroke (3), but the survivors are often left with disabilities. In addition to the sequelae of acute neuronal damage, the 1-year post-stroke dementia (PSD) rates after first-ever and recurrent stroke are ~10 and 30...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration
Conclusion The developed and validated method to quantify neurounina-1 in beagle dog plasma using LC-MS/MS presented sensitivity and selectivity, thus allowing the rapid and precise determination of the pharmacokinetics of this neuroprotective compound working in the low nanomolar range. Ethics Statement This study was carried out in accordance with the recommendations of the general ethical guidelines established by the Brazilian Society for Laboratory Animal Science (SBCAL). The protocol was approved by the Committee for Ethics in Animal Use – State University of Campinas (CEUA/UNICAMP, protocol n° 3340-...
Source: Frontiers in Pharmacology - April 24, 2019 Category: Drugs & Pharmacology Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

A Population-Based Survey of Stroke Knowledge in Argentina: The SIFHON Study
Conclusions: This study represents the largest stroke awareness survey in a Spanish-speaking population. There was good recognition of some basic facts of stroke. However, the population had poor knowledge of prevalence and severity of the disease, transient ischemic attacks, and treatment availability.Neuroepidemiology
Source: Neuroepidemiology - April 15, 2019 Category: Epidemiology Source Type: research

Cell-Based Therapies for Stroke: Promising Solution or Dead End? Mesenchymal Stem Cells and Comorbidities in Preclinical Stroke Research
Conclusion The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

A time series analysis of the relationship between apparent temperature, air pollutants and ischemic stroke in Madrid, Spain.
This study analyzes the temporal pattern of ischemic stroke (IS) in Madrid, Spain, during a 13-year period (2001-2013), and the relationship between ischemic stroke (admissions and deaths) incidence and environmental factors on a daily scale by using a quasi-Poisson regression model. To assess potential delayed and non-linear effects of air pollutants and Apparent Temperature (AT), a biometeorological index which represents human thermal comfort on IS, a lag non-linear model was fitted in a generalized additive model. The mortality rate followed a downward trend over the studied period, however admission rates progressivel...
Source: Environmental Research - March 29, 2019 Category: Environmental Health Authors: Royé D, Zarrabeitia MT, Riancho J, Santurtún A Tags: Environ Res Source Type: research

Performance of the RACE Score for the Prehospital Identification of Large Vessel Occlusion Stroke in a Suburban/Rural EMS Service.
CONCLUSION: The RACE scale demonstrated acceptable discrimination, yet the sensitivity and positive predictive value were lower in this cohort of EMS professionals in the U.S. than in the original validation study conducted in Spain. Further work is needed to determine the optimal prehospital screening tool for identification of LVO. PMID: 30668202 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - January 23, 2019 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Determinants of Informal Care, Burden, and Risk of Burnout in Caregivers of Stroke Survivors Clinical Sciences
Conclusions—This study reveals the heavy burden borne by the caregivers of stroke survivors. Our analysis also identifies explanatory and predictive variables for the likelihood of receiving informal care, caregiver burden, and high risk of burnout.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Juan Oliva–Moreno, Luz Maria Pena–Longobardo, Javier Mar, Jaime Masȷuan, Stephane Soulard, Nuria Gonzalez–Roȷas, Virginia Becerra, Miguel Angel Casado, Covadonga Torres, Maria Yebenes, Manuel Quintana, Jose Alvarez–Sa Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Effect of informed consent on patient characteristics in a stroke thrombolysis trial
Conclusions: Patients recruited by proxy consent were older, had more severe strokes, and had higher prevalence of aphasia than those with capacity to give personal consent. Variations in the manner of consent across countries may influence trial results. Clinicaltrials.gov and Clinicaltrialsregister.eu identifiers: NCT01525290 (clinicaltrials.gov); 2011-005906-32 (clinicaltrialsregister.eu).
Source: Neurology - September 25, 2017 Category: Neurology Authors: Thomalla, G., Boutitie, F., Fiebach, J. B., Simonsen, C. Z., Nighoghossian, N., Pedraza, S., Lemmens, R., Roy, P., Muir, K. W., Heesen, C., Ebinger, M., Ford, I., Cheng, B., Cho, T.-H., Puig, J., Thijs, V., Endres, M., Fiehler, J., Gerloff, C. Tags: MRI, All Clinical trials, All Cerebrovascular disease/Stroke, Clinical trials Methodology/study design, All Ethics in Neurology/Legal issues ARTICLE Source Type: research

Biological age is better than chronological as predictor of 3-month outcome in ischemic stroke
Conclusions: B-age, estimated by DNA methylation, is an independent predictor of ischemic stroke outcome regardless of chronological years.
Source: Neurology - August 21, 2017 Category: Neurology Authors: Soriano-Tarraga, C., Mola-Caminal, M., Giralt-Steinhauer, E., Ois, A., Rodriguez-Campello, A., Cuadrado-Godia, E., Gomez-Gonzalez, A., Vivanco-Hidalgo, R. M., Fernandez-Cadenas, I., Cullell, N., Roquer, J., Jimenez-Conde, J. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology, All Genetics ARTICLE Source Type: research

Cognitive performance following lacunar stroke in Spanish‐speaking patients: results from the SPS3 trial
ConclusionsMild cognitive impairment in Secondary Prevention of Small Subcortical Strokes Spanish‐speaking patients with recent lacunar stroke is highly prevalent but has a different pattern to that observed in English‐speaking patients. A combination of socio‐demographics, stroke biology, and stroke care may account for these differences.
Source: International Journal of Stroke - May 14, 2015 Category: Neurology Authors: Claudia Jacova, Lesly A. Pearce, Ana M. Roldan, Antonio Arauz, Jorge Tapia, Raymond Costello, Leslie A. McClure, Robert G. Hart, Oscar R. Benavente Tags: Research Source Type: research