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Total 78 results found since Jan 2013.

Trajectories of positive aspects of caregiving among family caregivers of stroke-survivors: the differential impact of stroke-survivor disability.
Conclusions Care professionals should be mindful of the heterogeneity in the longitudinal pattern of positive feelings resulting from care provision among family caregivers of stroke-survivors, and the differential impact of stroke-survivor disability on the pattern of positive feelings. Younger caregivers as well as family caregivers who have low positive feelings at the start of their caregiver journey and experience worsening functional disability of their care recipient (stroke-survivor) require greater attention and support. PMID: 29577825 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 26, 2018 Category: Neurology Authors: Malhotra R, Chei CL, Menon EB, Chow WL, Quah S, Chan A, Ajay S, Matchar DB Tags: Top Stroke Rehabil Source Type: research

Neurogenic heterotopic ossification after a stroke: diagnostic and radiological challenges.
Abstract Heterotopic ossification (HO) is the aberrant formation of ectopic bone within the soft tissues, of which the aetiology is usually either traumatic or neurogenic. Neurogenic HO is a known but uncommon complication that occurs after a cerebral or spinal insult. The condition may present with a spectrum of symptoms and is often difficult to diagnose clinically. Although different imaging modalities have been used to diagnose HO, clinicians and radiologists may occasionally encounter radiological features of HO that may mimic other disease conditions. We herein report a rare case of neurogenic HO occurring i...
Source: Singapore Medical Journal - August 1, 2014 Category: Journals (General) Authors: Pek CH, Lim MC, Yong R, Wong HP Tags: Singapore Med J Source Type: research

Stroke Literacy in Singapore: Data From a Survey of Public Housing Estate Residents.
Conclusion: In a sample of Singaporean adults residing in a public housing estate, we found evidence of poor stroke literacy, highlighting the need for comprehensive population-based education efforts. There is a role for opportunistic education among those at higher risk of stroke. PMID: 25341630 [PubMed - as supplied by publisher]
Source: Annals of the Academy of Medicine, Singapore - September 1, 2014 Category: Journals (General) Authors: Lim W, Chuang DF, Chue KM, Lee DZ, Leong NJ, Ng ZG, Peng K, Shen X, Tham YN, Wang K, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Discriminant Analysis for predictor of falls in stroke patients by using the Berg Balance Scale.
Conclusion: The results of this study suggest that BBS score is a strong predictor of falls in stroke patients. As balance is closely related to the risk of falls in hospitalised stroke patients, BBS might be useful in the prediction of falls. PMID: 25678051 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - February 13, 2015 Category: Journals (General) Authors: Maeda N, Urabe Y, Murakami M, Itotani K, Kato J Tags: Singapore Med J Source Type: research

Underutilisation of Guideline-based Therapy Primary Prevention among Patients Presenting with AF-related Ischaemic Stroke.
PMID: 26377061 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - July 1, 2015 Category: Journals (General) Authors: Fabiaña N, Ramaswami AP, Ang ES Tags: Ann Acad Med Singapore Source Type: research

Surveys of Stroke Patients and Their Next of Kin on Their Opinions towards Decision-Making and Consent for Stroke Thrombolysis.
CONCLUSION: The survey found that in the decision-making process for stroke thrombolysis, there was no clear consensus on the preference for the decision maker of the mentally incapacitated patient. In Singapore, there is a strong influence of the NOK in decision-making for thrombolysis. PMID: 28263342 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 31, 2017 Category: Journals (General) Authors: Angamuthu N, Queck KK, Menon S, Ho SS, Ang E, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Predicting Pneumonia in Acute Ischaemic Stroke: Comparison of Five Prediction Scoring Models.
CONCLUSION: A(2)DS(2) , AIS-APS and Kwon's scores performed comparably in discriminating SAP in AIS patients. PMID: 28733688 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 1, 2017 Category: General Medicine Authors: Tu TM, Phua SS, Acharyya S, Ng WM, Oh DC Tags: Ann Acad Med Singapore Source Type: research

Independent predictors of medication adherence among Singaporean patients following an ischemic stroke or transient ischemic attack
ConclusionMedication adherence was poor in Singaporean patients following an ischemic stroke or transient ischemic attack. The independent predictors identified in this study will support healthcare professionals to develop tailored intervention to improve medication adherence among this group of patients. Relevance to clinical practiceNurses play an important role in promoting patients’ medication adherence. Helping stroke patients understand the long‐term benefits of their medications is essential to enhance patients’ medication adherence and results in better health outcomes.This article is protected by copyright....
Source: Journal of Clinical Nursing - August 9, 2017 Category: Nursing Authors: Wenru Wang, Gerk Sin Chia, Il Fan Tan, Siew Noi Janis Tye, Xiaona Wang, Birong Zhu, Ying Jiang Tags: Original Article Source Type: research

Independent predictors of medication adherence among Singaporean patients following an ischaemic stroke or transient ischaemic attack
ConclusionMedication adherence was poor in Singaporean patients following an ischaemic stroke or transient ischaemic attack. The independent predictors identified in this study will support healthcare professionals to develop tailored intervention to improve medication adherence among this group of patients. Relevance to clinical practiceNurses play an important role in promoting patients’ medication adherence. Helping stroke patients understand the long‐term benefits of their medications is essential to enhance patients’ medication adherence and results in better health outcomes.
Source: Journal of Clinical Nursing - October 8, 2017 Category: Nursing Authors: Wenru Wang, Gerk Sin Chia, Il Fan Tan, Siew Noi Janis Tye, Xiaona Wang, Birong Zhu, Ying Jiang Tags: ORIGINAL ARTICLE Source Type: research

Developing a falls prevention program for community-dwelling stroke survivors in Singapore: client and caregiver perspectives - Xu T, O'Loughlin K, Clemson L, Lannin NA, Dean C, Koh G.
PURPOSE: Drawing on the perspectives of stroke survivors, family members and domestic helpers, this study explores participants' experiences of self-perceived fall risk factors after stroke, common fall prevention strategies used, and challenges to communi...
Source: SafetyLit - December 28, 2017 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Developing a falls prevention program for community-dwelling stroke survivors in Singapore: client and caregiver perspectives.
CONCLUSIONS: Reducing the risk of falls in community-dwelling stroke survivors seems to be more important than promoting community participation among caregivers. The study findings highlight that a structured and client-centered fall prevention program targeting stroke survivors and caregivers is needed in Singapore. Implications for rehabilitation Falls after stroke can lead to functional decline in gait and mobility and restricted self-care activities. Community-dwelling stroke survivors develop adaptive safety strategies after a fall and want to be socially connected. However, caregivers see the safety of the stroke su...
Source: Disability and Rehabilitation - December 25, 2017 Category: Rehabilitation Authors: Xu T, O'Loughlin K, Clemson L, Lannin NA, Dean C, Koh G Tags: Disabil Rehabil Source Type: research

Post Soft Care: Italian implementation of a post-stroke checklist software for primary care and identification of unmet needs in community-dwelling patients
AbstractThe needs of community-dwelling stroke patients are often not fully addressed. The Global Stroke Community Advisory Panel had developed the Post Stroke Checklist (PSC) with the aim of standardizing long-term stroke assessment and consequently care of patients. PSC has been validated for UK and Singapore, and an Italian version has been proposed. The aim of this study is to assess the needs of community-dwelling Italian stroke patients using an online version of PSC. Secondary aim is to assess utility of PSC for patients and clinicians. The PSC was administered to a sample of 64 patients with stroke in Italy by gene...
Source: Neurological Sciences - January 1, 2018 Category: Neurology Source Type: research

Therapists' perspectives on adapting the Stepping On falls prevention programme for community-dwelling stroke survivors in Singapore.
CONCLUSIONS: Rehabilitation therapists describe challenges in addressing fall prevention within a stroke context, and findings highlight the need for a structured, stroke-specific fall prevention programme rather than a more general approach to education and training. Contextual components identified provide valuable inputs towards the development of a culturally relevant fall prevention programme for stroke survivors in Singapore. Implications for Rehabilitation Stroke survivors living in the community are at a high risk of falls. A structured and culturally relevant fall prevention programme for community-living stroke s...
Source: Disability and Rehabilitation - May 18, 2018 Category: Rehabilitation Authors: Xu T, O'loughlin K, Clemson L, Lannin NA, Koh G, Dean C Tags: Disabil Rehabil Source Type: research

Therapists' perspectives on adapting the Stepping On falls prevention programme for community-dwelling stroke survivors in Singapore - Xu T, O'Loughlin K, Clemson L, Lannin NA, Koh G, Dean C.
This study investigates the perspectives of rehabilitation therapists on the implementation of fall prevention programmes with community-dwelling stroke survivors in the Singapore context, and elicits recommendations to adapt the Stepping On progr...
Source: SafetyLit - May 21, 2018 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Elderly Stroke Rehabilitation: Overcoming the Complications and Its Associated Challenges.
Authors: Lui SK, Nguyen MH Abstract There have been many advances in management of cerebrovascular diseases. However, stroke is still one of the leading causes of disabilities and mortality worldwide with significant socioeconomic burden. This review summarizes the consequences of stroke in the elderly, predictors of stroke rehabilitation outcomes, role of rehabilitation in neuronal recovery, importance of stroke rehabilitation units, and types of rehabilitation resources and services available in Singapore. We also present the challenges faced by the elderly stroke survivors in the local setting and propose strate...
Source: Current Gerontology and Geriatrics Research - July 29, 2018 Category: Geriatrics Tags: Curr Gerontol Geriatr Res Source Type: research

The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time-Stratified Case-Crossover Study in a City-State With Seasonal Exposure to the Southeast Asian Haze Problem
ConclusionWe found a short-term elevated risk of ischemic stroke after exposure to air pollution. These findings have public health implications for stroke prevention and emergency health services delivery.
Source: Annals of Emergency Medicine - August 30, 2018 Category: Emergency Medicine Source Type: research

Predictors of functional outcome in patients with stroke thrombolysis in a tertiary hospital in Malaysia.
CONCLUSION: Our newly developed Malaysian IV rt-PA service is safe, with similar outcomes to the published literature. Functional outcome after thrombolysis was associated with baseline NIHSS scores and DM. PMID: 30488077 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - November 29, 2018 Category: General Medicine Authors: Tai MS, Goh KJ, Kadir KAA, Zakaria MI, Yap JF, Tan KS Tags: Singapore Med J Source Type: research

Adherence to the Mediterranean diet and risk of stroke and stroke subtypes
AbstractSeveral meta-analyses including a small number of cohorts showed inverse associations between the Mediterranean Diet (MedDiet) and risk of stroke. However, it remains unclear whether such a relation varies by region of the study population or by major subtypes of stroke. We searched PubMed and EMBASE databases for relevant studies and we further included unpublished results from the Singapore Chinese Health Study (N = 57,078) and the Seguimiento Universidad de Navarra (SUN) study (N  =  12,670). We used a random-effects model to calculate summary relative risk (RR) with 95% confidence intervals (CI) of stro...
Source: European Journal of Epidemiology - March 1, 2019 Category: Epidemiology Source Type: research

A Rare but Disabling Stroke.
PMID: 30997481 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - February 28, 2019 Category: General Medicine Authors: Lau KF, Tan KS, Goh KJ, Ramli N, Tai SM Tags: Ann Acad Med Singapore Source Type: research

Temporal Trends and Predictors of Drug Utilization and Outcomes in First-Ever Stroke Patients: A Population-Based Study Using the Singapore Stroke Registry
ConclusionsPrescription of secondary stroke preventive medications (particularly in ischemic stroke) was associated with more favorable outcomes, highlighting the importance of physician adherence to evidence-based pharmacotherapy.
Source: CNS Drugs - July 15, 2019 Category: Neurology Source Type: research

Serum S100 β as a predictor of severity and outcomes for mixed subtype acute ischaemic stroke.
CONCLUSION: High serum S100β is associated with unfavourable outcome for mixed subtype AIS. Cut-off values of S100β72hrs and ∆S100β were optimal for predicting unfavourable stroke outcome. PMID: 31317198 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - July 10, 2019 Category: General Medicine Authors: Sakdejayont S, Pruphetkaew N, Chongphattararot P, Nanphan P, Sathirapanya P Tags: Singapore Med J Source Type: research

Optimal placement of electrodes for treatment of post-stroke dysphagia by neuromuscular electrical stimulation combined with effortful swallowing.
CONCLUSION: Horizontal placement of the NMES electrodes on the suprahyoid and infrahyoid muscles for the treatment of post-stroke dysphagia by NMES combined with effortful swallowing was more effective than the horizontal and vertical placement of electrodes on the suprahyoid and infrahyoid muscles, respectively, and their vertical placement above the hyoid bone and cricoid cartilage. PMID: 31680183 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - November 3, 2019 Category: General Medicine Authors: Huh JW, Park E, Min YS, Kim AR, Yang WJ, Oh HM, Nam TW, Jung TD Tags: Singapore Med J Source Type: research

Use of Selective Serotonin Reuptake Inhibitors and Outcomes in Stroke Rehabilitation: A Prospective Observational Pilot Cohort Study
ConclusionSSRI therapy did not improve disability and QOL in multi-ethnic Asian patients with first-ever stroke undergoing rehabilitation.
Source: Drugs in R&D - November 17, 2019 Category: Drugs & Pharmacology Source Type: research

An Unusual Cause of Stroke-Like Symptoms in an Elderly Patient.
PMID: 31737897 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - August 31, 2019 Category: General Medicine Authors: Kee CK, Ngam PI, Tan AP Tags: Ann Acad Med Singapore Source Type: research

Truncal impairment after stroke: clinical correlates, outcome and impact on ambulatory and functional outcomes after rehabilitation.
CONCLUSION: Truncal impairment was common and improvements in trunk performance were seen after rehabilitation. Trunk performance was significantly correlated to stroke severity, upper and lower limb motor power, cognition and neglect. As admission trunk performance predicted discharge functional and ambulatory status, it is recommended that trunk performance be evaluated for all patients with stroke. PMID: 31788705 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - December 1, 2019 Category: General Medicine Authors: Kong KH, Ratha Krishnan R Tags: Singapore Med J Source Type: research

Declining Stroke Mortality in Singapore and The Challenges Ahead.
PMID: 31875467 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - September 30, 2019 Category: General Medicine Authors: Hung J, De Silva DA, Seet RC Tags: Ann Acad Med Singapore Source Type: research

ACT-FAST: a quality improvement project to increase the percentage of acute stroke patients receiving intravenous thrombolysis within 60 minutes of arrival at the emergency department.
CONCLUSION: The interventions resulted in an increasing but non-significant trend of acute stroke patients receiving thrombolysis within 60 minutes. Outcomes will be monitored for a longer duration to demonstrate trends and sustainability. PMID: 32227791 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - March 30, 2020 Category: General Medicine Authors: Chiu LQ, Quek DYJ, Salihan RB, Ng WM, Othman RB, Lee CH, Oh DCT Tags: Singapore Med J Source Type: research

Influence of chronic kidney disease and haemodialysis on stroke outcome
CONCLUSION: Despite significant functional and neurological improvements following rehabilitation, stroke patients with underlying CKD had higher average duration of hospital stay, more recurrent hospitalisations and poorer survival outcomes than those without underlying CKD. This could be attributed to the complications associated with CKD rather than stroke. Multidisciplinary community rehabilitation may be an alternative to reduce recurrent hospitalisations and morbidity in this group of patients. PMID: 32241068 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - April 2, 2020 Category: General Medicine Authors: Pande SD, Morris J Tags: Singapore Med J Source Type: research

Fatal Cerebral Haemorrhage in a Thrombolysed Patient with Ischaemic Stroke Who Developed Interval Thrombocytopaenia from Acute Dengue Infection.
PMID: 32246712 [PubMed - as supplied by publisher]
Source: Annals of the Academy of Medicine, Singapore - January 31, 2020 Category: General Medicine Authors: Pang YH, Divakar TG, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Temporal Trends and Patient Characteristics Associated With Drug Utilisation After First-Ever Stroke: Insights From Chronic Disease Registry Data in Singapore.
CONCLUSION: This study reveals changes in prescription behaviour over time in a multiethnic Asian population with first-ever stroke. Patient characteristics including younger age, Malay ethnicity and certain comorbidities (i.e. hyperlipidaemia, atrial fibrillation) were associated with the combined use of all 3 guideline medications among ischaemic stroke patients. PMID: 32301477 [PubMed - in process]
Source: Ann Acad Med Singapo... - February 29, 2020 Category: General Medicine Authors: Yeo SH, Toh MPH, Lee SH, Seet RC, Wong LY, Yau WP Tags: Ann Acad Med Singapore Source Type: research

Psychometric Properties of the National Institute of Neurological Disorders and Stroke and Canadian Stroke Network Neuropsychological Battery in an Asian Older Adult Sample
Despite the wide usage of the National Institute of Neurological Disorders and Stroke and Canadian Stroke Network (NINDS-CSN) neuropsychological battery for the detection of vascular cognitive impairment, its reliability and validity have not been established. Therefore, the present study established the psychometric properties of the battery in cognitively normal older adults in a clinical setting in Singapore.
Source: Journal of the American Medical Directors Association - May 18, 2020 Category: Health Management Authors: Kimberly A. Chew, Eddie J.Y. Chong, Christopher L.H. Chen, Xin Xu Tags: Original Study - Brief Report Source Type: research

Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
AbstractThe Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and affecting healthcare systems across the world. Singapore has escalated its alert level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying severe disease with community spread. We aimed to study the overall volume of AIS cases and the delivery of hyperacute stroke services during DORSCON Orange. This was a single-centre, observational cohort study performed at a comprehensive stroke centre responsible for AIS cases in the western region of Singapore, as well as providing care for COVID-19 patients. All AIS patients revie...
Source: Journal of Thrombosis and Thrombolysis - July 12, 2020 Category: Hematology Source Type: research

Stroke Care Services in Singapore During COVID-19 Pandemic —A National Perspective
Stroke is a significant cause of admission to Singapore's acute care hospitals. Because of the current COVID-19 pandemic, there have been major changes in the stroke care system. On calling for the public ambulance, those suspected to have COVID-19 infection are taken to the National Center for Infectious Diseases. Otherwise, on arrival at the emergency room, all cases with fever or respiratory symptoms [COVID-19 suspect patients (CSPs)] are evaluated separately by staff wearing full personal protective equipment (PPE). Triage is not delayed. CSPs needing hyperacute therapies are sent to a specially prepared scanner; if no...
Source: Frontiers in Neurology - July 27, 2020 Category: Neurology Source Type: research

Inactive bowel movement and stroke are associated with increased risks of mild cognitive impairment among community-living Singapore elderly.
Abstract Mild cognitive impairment (MCI), as a preclinical phase of dementia, provides an invaluable time window for intervention. Besides several proposed modifiable risk factors, the associations of MCI with dietary habits and bowel movement are not well clarified. We thus conducted a cross-sectional study of community-living Singapore elderly and focused on the relationship of clinically diagnosed MCI with dietary habits and bowel movement frequencies. The multiple logistic regression results showed that frequent (≥4 days per week) fruit consumption (P = 0.004), active (≥4 days per week) bowel movement with...
Source: Aging - September 8, 2020 Category: Biomedical Science Authors: Huang KY, Tang XY, Yang L, Zhang ZY, Ye KX, Shen QF, Wang X, Zhu XH, Huang XW, Lu GD, Feng L Tags: Aging (Albany NY) Source Type: research

The Experiences of Couples Affected by Stroke and Nurses Managing Patient Rehabilitation: A Descriptive Study in Singapore
Conclusions/Implications for Practice The meaning of recovery differs between patients and their informal and formal care providers. This issue should be explored in patient–provider conversations, as these conversations highlight the values and preferences that affect the stroke recovery trajectory. Enhancing shared decision making by patients, spousal caregivers, and healthcare providers during the stroke trajectory may promote the alignment of values that are critical to the stroke recovery experience. Further research into whether and how to incorporate shared decision making in rehabilitation hospital settings as ...
Source: Journal of Nursing Research - September 11, 2020 Category: Nursing Tags: ORIGINAL ARTICLES Source Type: research

Cost Effectiveness of Genotype-Guided Antiplatelet Therapy in Asian Ischemic Stroke Patients: Ticagrelor as an Alternative to Clopidogrel in Patients with CYP2C19 Loss of Function Mutations
ConclusionThis study suggests that it is cost effective to screen for LOF mutations in the CYP2C19 gene in ischemic stroke populations, with ticagrelor as a substitute for clopidogrel in those with LOF mutations.
Source: Clinical Drug Investigation - September 20, 2020 Category: Drugs & Pharmacology Source Type: research

Anticoagulation needs in asians with atrial fibrillation: a mythbuster.
Abstract Atrial fibrillation (AF) has long been known to increase the risk of stroke. As a result, relevant international guidelines recommend that measures to reduce the risk of thrombus formation should be considered in all patients presenting with AF. Based on risk assessment scores, patients would then receive either thrombocyte aggregation inhibitors or oral anticoagulants. Despite this advice, compliance rates with the recommendations are poor across all countries surveyed. Evidence from the Global Anticoagulant Registry in the Field (GARFIELD) registry shows that major deviation from guidelines is due in la...
Source: Annals of the Academy of Medicine, Singapore - May 1, 2014 Category: Journals (General) Authors: Aribou ZM, Mondry A Tags: Ann Acad Med Singapore Source Type: research

Coarctation of the aorta: nonsurgical treatment using stent implantation.
CONCLUSION: This is the first reported series in Singapore on the nonsurgical treatment of CoAs in adult patients using stents during interventional cardiac catheterisation. This less invasive procedure may lead to a new paradigm shift with regard to the treatment of CoA. PMID: 25017404 [PubMed - in process]
Source: Singapore Medical Journal - June 1, 2014 Category: Journals (General) Authors: Ang HL, Lim CW, Hia C, Yip J, Quek SC Tags: Singapore Med J Source Type: research

The use of virtual reality-based therapy to augment poststroke upper limb recovery.
Abstract Stroke remains one of the major causes of disability worldwide. This case report illustrates the complementary use of biomechanical and kinematic in-game markers, in addition to standard clinical outcomes, to comprehensively assess and track a patient's disabilities. A 65-year-old patient was admitted for right-sided weakness and clinically diagnosed with acute ischaemic stroke. She participated in a short trial of standard stroke occupational therapy and physiotherapy with additional daily virtual reality (VR)-based therapy. Outcomes were tracked using kinematic data and conventional clinical assessments...
Source: Singapore Medical Journal - July 1, 2015 Category: Journals (General) Authors: Samuel GS, Choo M, Chan WY, Kok S, Ng YS Tags: Singapore Med J Source Type: research

Disability in Singapore's Elderly Population.
CONCLUSION: The findings highlighted specific factors associated with disability in this multiethnic population. The identification of these factors would lead the way to the development of appropriate interventions. PMID: 27523509 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 30, 2016 Category: Journals (General) Authors: Mahesh M, Abdin E, Vaingankar JA, Picco L, Jeyagurunathan A, Shafie SB, Pang S, Sagayadevan V, Seow E, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Prevalence and Risk Factors of Caregiver Dependence among Older Adults in a Southeast Asian Population.
CONCLUSION: Various sociodemographic and health-related conditions were significantly associated with caregiver dependence. Dependent older adults will put greater demands on health and social services, resulting in greater healthcare expenditures. Hence, effective planning, services and support are crucial to meet the needs of dependent older adults and their caregivers. PMID: 27922142 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 31, 2016 Category: Journals (General) Authors: Picco L, Abdin E, Vaingankar JA, Pang S, Shafie S, Sambasivam R, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Predictive Factors of Developing Type 2 Diabetes Mellitus, Acute Myocardial Infarction and Stroke in a Cohort with Impaired Fasting Glucose in Singapore
In Singapore, the prevalence of DM in residents aged 18 to 69 years has increased from 8.2% in 2004 to 11.3% in 2010. More than half (51.4%) of residents who were found to have DM were previously undiagnosed [1].
Source: Diabetes Research and Clinical Practice - July 19, 2017 Category: Endocrinology Authors: Dennis Bingzhu Chia, Lai Yin Wong, Daveon Yu Kai Liu, Matthias Paul Han Sim Toh Source Type: research

Boehringer Aims High with Angels Initiative
An innovative scheme to create a community of 1,500 stroke-ready hospitals across Europe has been recognized with the Most Valuable HCP/Healthcare Award at the European arm of theeyeforpharma Awards 2017.The Angel ’s Initiative from Boehringer Ingelheim – which aims to save 100,000 lives by May 2019 – was voted the winner in a unanimous decision by the expert panel of judges.Only one-third of stroke patients in Europe have access to organized stroke care, while just one per cent of stroke patients in emerging markets are provided with lifesaving treatments. In response, the Angels Initiative is working to establish m...
Source: EyeForPharma - April 25, 2017 Category: Pharmaceuticals Authors: Danielle Barron Source Type: news

Commentary on “Rehabilitation Outcomes Associated With Foreign Domestic Workers as Caregivers”
The purpose of this commentary is to illuminate the role of foreign domestic workers (FDW) as caregivers for patients undergoing rehabilitation in Asia. The authors of a published study in this issue of the Archives of Physical Medicine and Rehabilitation investigate the association between the characteristics of caregivers for patients recovering from sub-acute stroke and the rehabilitation outcomes of those patients in Singapore. The investigators examined over 4,000 caregivers and one of the findings showed that after controlling for characteristics of both caregivers and patients, there was a significant and negative a...
Source: Archives of Physical Medicine and Rehabilitation - May 27, 2017 Category: Rehabilitation Authors: Frances M. Yang, Solon T. Kao Tags: Commentary Source Type: research

Validation of Prognostic Models to predict Early Mortality in Spontaneous Intracerebral Hemorrhage: A Cross Sectional Evaluation of a Singapore Stroke Database
Numerous scores have been developed for prognostication of outcomes in intracerebral hemorrhage (ICH). Prediction models must be validated internally and externally before they are considered widely applicable. We aim to independently externally validate and compare three prediction models (ICH score, ICH grading scale (ICH-GS) and simplified ICH (sICH)) in our population, which has not been previously done.
Source: World Neurosurgery - October 17, 2017 Category: Neurosurgery Authors: Julian Xinguang Han, Angela An Qi See, Nicolas Kon Kam King Tags: Original article Source Type: research

Epidemiology of a Rare Event
Retinal emboli are rare, with a prevalence in most of the relatively few studies on the subject, to my knowledge, of approximately 1 in 100 adults and an even smaller annual incidence. The study by Cheung et al in the present issue ofJAMA Ophthalmology involves the multiethnic population of Singapore and found that retinal emboli were present in only 88 of 9978 individuals who had retinal photographs (0.9%). This randomly selected sample of adults aged 40 to 80 years comprised, in almost equal numbers, of members of the 3 major ethnic groups residing in Singapore: Chinese, Malay, and Indian. Cheung et al provided data rele...
Source: JAMA Ophthalmology - October 1, 2017 Category: Opthalmology Source Type: research

Outcomes of primary percutaneous coronary intervention in acute myocardial infarction due to unprotected left main thrombosis: The Asia ‐Pacific Left Main ST‐Elevation Registry (ASTER)
ConclusionsSTEMI from culprit unprotected left main coronary artery stenosis is associated with significant mortality and morbidity. Emergency PCI provides an important treatment option in this high‐risk group, but in‐hospital mortality remains high.
Source: Journal of Interventional Cardiology - November 16, 2017 Category: Cardiology Authors: Jonathan Yap, Gagan D. Singh, Jung ‐Sun Kim, Krishan Soni, Kelvin Chua, Alvin Neo, Choong Hou Koh, Ehrin J. Armstrong, Stephen W. Waldo, Kendrick A. Shunk, Reginald I. Low, Myeong‐Ki Hong, Yangsoo Jang, Khung Keong Yeo Tags: ORIGINAL INVESTIGATION Source Type: research

Glycaemic, Blood Pressure and Low Density Lipoprotein Cholesterol Control in Adult Patients with Diabetes in Singapore: A Review of Singapore Literature Over Two Decades.
CONCLUSION: Mirroring global patterns, the glycaemic, BP and LDL-C control in adult diabetic patients in Singapore do not appear to be treated to target in the majority of patients. PMID: 29177366 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 1, 2017 Category: General Medicine Authors: Poh Z, Venkataraman K, Toh SE, Low LL Tags: Ann Acad Med Singapore Source Type: research

Factors Associated with Chronic Kidney Disease and Their Clinical Utility in Primary Care Clinics in a Multi-Ethnic Southeast Asian Population
Conclusions: CKD prevalence in our Southeast Asian population is high and under-documented even in high-risk patients. Our findings highlight factors associated with CKD, and the predictive value of hypertension, diabetes, and advancing age as EHR-based screening targets for CKD. Our results also suggest that complementary educational efforts will be needed to increase physician detection and optimize the management of CKD, especially in high risk and marginalized groups across all clinics in Singapore, and possibly in the region.Nephron
Source: Nephron - December 15, 2017 Category: Urology & Nephrology Source Type: research

Incidence of thromboembolic and bleeding events in patients with newly diagnosed nonvalvular atrial fibrillation: An Asian multicenter retrospective cohort study in Singapore
ConclusionsSAPT and DAPT are less effective than warfarin in NVAF patients. DOACs may be considered in view of lower risk of overall bleed.
Source: Clinical Cardiology - November 1, 2017 Category: Cardiology Authors: Xue Ting Wee, Lih Maan Ho, Han Kiat Ho, Joyce Yu ‐Chia Lee, Chun Wei Yap, Henry William, Linus Chong En Chan, Hooi Ching Tay, Cynthia Eei Mei Goh, Doreen Su‐Yin Tan Tags: CLINICAL INVESTIGATIONS Source Type: research