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Total 83 results found since Jan 2013.

Effect of clopidogrel in bone healing-experimental study in rabbits.
CONCLUSION: Our results indicate that maintenance of perioperative clopidogrel treatment does not negatively affect bone healing but rather promotes it. Further research is needed in order to find useful applications of this finding. PMID: 31908992 [PubMed]
Source: World Journal of Orthopaedics - January 9, 2020 Category: Orthopaedics Tags: World J Orthop Source Type: research

Community Knowledge and Awareness of Stroke in New Zealand
Introduction: Community knowledge and stroke awareness is crucial for primary prevention of stroke and timely access to stroke treatments including acute reperfusion therapies. We conducted a national telephone survey to quantify the level of community stroke awareness. Methods: A random sample of 400 adults in New Zealand (NZ), stratified by the 4 main ethnic groups, was surveyed. Eligible participants answered stroke awareness questions using both unprompted (open-ended) and prompted questions (using a list).
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2019 Category: Neurology Authors: Rita V. Krishnamurthi, Suzanne Barker-Collo, Peter Alan Barber, Lynette J. Tippett, John C. Dalrymple-Alford, Bronwyn Tunnage, Susan Mahon, Priyakumari G. Parmar, Melanie Moylan, Valery L. Feigin Source Type: research

Impact of the national public 'FAST' campaigns.
CONCLUSION: The New Zealand stroke public campaigns were associated with a rise in stroke symptom recognition, time-critical awareness, ambulance stroke notifications and thrombolysis rates. The uncontrolled nature of this study necessitates consideration of other potential contributing factors when interpreting results. Ongoing campaigns for continual reinforcement appear important. PMID: 31830016 [PubMed - in process]
Source: New Zealand Medical Journal - December 14, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Should This Patient Be Screened for Atrial Fibrillation?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2019 Dec 03;171(11):828-836 Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Abstract Atrial fibrillation (AFib) is the most common type of cardiac arrhythmia, affecting 2.7 million to 6.1 million persons in the United States. Although some persons with AFib have no symptoms, others do. For those without symptoms, AFib may be detected by 12-lead electrocardiogram (ECG), single-lead monitors (such as ambulatory blood pressure monitors and pulse oximeters), or consumer devices (such as wearable monitors and smartphones). Pulse pa...
Source: Annals of Internal Medicine - December 3, 2019 Category: Internal Medicine Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Tags: Ann Intern Med Source Type: research

How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Health - November 20, 2019 Category: Consumer Health News Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news

Dog Ownership Linked To 24% Lower Risk Of Dying Early, Research Shows
(CNN) — Need an excellent reason to add a dog to your life? How about living longer? “Our analysis found having a dog is actually protective against dying of any cause,” said Mount Sinai endocrinologist Dr. Caroline Kramer, lead author of a new systematic review of nearly 70 years of global research published Tuesday in “Circulation,” a journal of the American Heart Association. The review of the health benefits of man’s best friend analyzed research involving nearly 4 million people in the United States, Canada, Scandinavia, New Zealand, Australia and the United Kingdom. “Dog owne...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 8, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Featured Health News Offbeat Syndicated CBSN Boston CNN Dogs Source Type: news

Incidence of stroke and traumatic brain injury in New Zealand: contrasting the BIONIC and ARCOS-IV studies.
CONCLUSIONS: Differences in TBI and stroke incidence suggest targeting prevention very differently for the two groups. Incidence profiles suggest TBI is much more common; and a need to target males and those of Māori ethnicity for TBI prevention. PMID: 31563926 [PubMed - in process]
Source: New Zealand Medical Journal - October 1, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia).
Abstract Utstein-style reporting templates provide a structured framework with which to compare systems of care for cardiac arrest. The 2004 Utstein reporting template encompassed both out-of-hospital and in-hospital cardiac arrest. A 2015 update of the Utstein template focused on out-of-hospital cardiac arrest, which makes this update of the in-hospital template timely. Representatives of the International Liaison Committee on Resuscitation developed an updated in-hospital Utstein reporting template iteratively by meeting face-to-face, by teleconference, and by online surveys between 2013 and 2018. Data elements ...
Source: Circulation - September 16, 2019 Category: Cardiology Authors: Nolan JP, Berg RA, Andersen LW, Bhanji F, Chan PS, Donnino MW, Lim SH, Ma MH, Nadkarni VM, Starks MA, Perkins GD, Morley PT, Soar J, Utstein Collaborators Tags: Circulation Source Type: research

Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom Scores.
Conclusions: We provide evidence that fALFF is sensitive to changes in poststroke depressive symptom severity and implicates frontostriatal and cerebellar regions, consistent with previous studies. The use of multiband analysis could be an effective method to examine neural correlates of depression after stroke. The START-PrePARE trial is registered with the Australian New Zealand Clinical Trial Registry, number ACTRN12610000987066. PMID: 31467520 [PubMed - in process]
Source: Neural Plasticity - September 1, 2019 Category: Neurology Authors: Goodin P, Lamp G, Vidyasagar R, Connelly A, Rose S, Campbell BCV, Tse T, Ma H, Howells D, Hankey GJ, Davis S, Donnan G, Carey LM Tags: Neural Plast Source Type: research

The Role of Interventional Radiologists in Acute Stroke Interventions: A Joint Statement from the Australia and New Zealand Society of Neuroradiology (ANZSNR), the Society of Neurointerventional Surgery (SNIS), the United Kingdom Neurointerventional Group (UKNG), the British Society of Neuroradiology (BSNR), and the European Society for Minimally Invasive, Neurological Therapy (ESMINT)
Publication date: September 2019Source: Journal of Vascular and Interventional Radiology, Volume 30, Issue 9Author(s): Jason Wenderoth, William McAuliffe, Alan Coulthard, Peter Mitchell, Adam Arthur, Justin F. Fraser, Norman McConachie, Andrew Clifton, Peter Flynn, Robert Crossley, Patrick Brouwer, Zsolt Kulscar, Jens Fiehler
Source: Journal of Vascular and Interventional Radiology - August 22, 2019 Category: Radiology Source Type: research

The Role of Interventional Radiologists in Acute  Stroke Interventions: A Joint Statement from the Australia and New Zealand Society of Neuroradiology (ANZSNR), the Society of Neurointerventional Surgery (SNIS), the United Kingdom Neurointerventional Group (UKNG), the British Society of Neuroradiology (BSNR), and the European Society for Minimall y Invasive, Neurological Therapy (ESMINT)
We read with interest the article by representatives of European Board of Interventional Radiology, Society of International Radiology, and International RadioSurgery Association (1). The interest of interventional radiologists in mechanical thrombectomy (MT) is welcome, but the cognitive/procedural aspects of MT must be considered along with the complex processes and resources required for service implementation. Training for all proceduralists must be consistent, MT proceduralists ’ posttraining performance must meet satisfactory benchmarks, and MT centers’ outcomes must be acceptable.
Source: Journal of Vascular and Interventional Radiology : JVIR - August 22, 2019 Category: Radiology Authors: Jason Wenderoth, William McAuliffe, Alan Coulthard, Peter Mitchell, Adam Arthur, Justin F. Fraser, Norman McConachie, Andrew Clifton, Peter Flynn, Robert Crossley, Patrick Brouwer, Zsolt Kulscar, Jens Fiehler Tags: Commentary Source Type: research

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
Publication date: Available online 15 August 2019Source: The LancetAuthor(s): Marko Mrkobrada, Matthew T.V. Chan, David Cowan, Douglas Campbell, Chew Yin Wang, David Torres, German Malaga, Robert D. Sanders, Manas Sharma, Carl Brown, Alben Sigamani, Wojciech Szczeklik, Mukul Sharma, Gordon Guyatt, Eric E. Smith, Ronit Agid, Adam A. Dmytriw, Jessica Spence, Nikesh R. Adunuri, Flavia K. BorgesSummaryBackgroundIn non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac surgery and is associated with ...
Source: The Lancet - August 17, 2019 Category: General Medicine Source Type: research

Mitral valve surgery with or without coronary bypass grafting: eight-year cohort study.
CONCLUSION: MVR+CABG compared to MVR patients had more comorbidities and greater operative risk, and were independently associated with higher operative mortality and composite morbidity, but not independently associated with higher long-term mortality. PMID: 31415499 [PubMed - in process]
Source: New Zealand Medical Journal - August 16, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

How much rehabilitation are our patients with stroke receiving?
CONCLUSION: There were delays in providing an initial community rehabilitation appointment and insufficient therapy intensity when comparing audit results to New Zealand Guideline expectations. As a result of this audit, recommendations for service improvements have been made. PMID: 31352474 [PubMed - in process]
Source: New Zealand Medical Journal - July 30, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Feasibility and acceptability of opportunistic screening to detect atrial fibrillation in Aboriginal adults.
CONCLUSION: The iECG device was well accepted within ACCHSs and was feasible to use to screen for AF among Aboriginal patients. Implications for public health: The device can be used in clinical and community settings to screen Aboriginal people for atrial fibrillation to help reduce rates of stroke and other cardiovascular diseases. PMID: 31141280 [PubMed - as supplied by publisher]
Source: Australian and New Zealand Journal of Public Health - May 29, 2019 Category: International Medicine & Public Health Authors: Macniven R, Gwynn J, Fujimoto H, Hamilton S, Thompson SC, Taylor K, Lawrence M, Finlayson H, Bolton G, Dulvari N, Wright DC, Rambaldini B, Freedman B, Gwynne K Tags: Aust N Z J Public Health Source Type: research

Development and Feasibility of a Pacific-Focused Community Weight Management Program
Obesity is a significant public health issue in New Zealand, where two thirds of adults are overweight or obese.1 In New Zealand, Pacific people have a greater burden of overweight and obesity than others; 90% of Pacific adults experience overweight and obesity.1 Pacific rates of ischemic heart disease, stroke, high cholesterol, and high blood pressure are all also markedly greater than for other New Zealanders.1
Source: Journal of Nutrition Education and Behavior - April 30, 2019 Category: Nutrition Authors: Susan Pirrit, Vili Nosa, Jennifer Utter Tags: GEM No. XXX Source Type: research

Stroke Prevention, Evaluation of Bleeding Risk, and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines
Publication date: May 2019Source: Canadian Journal of Cardiology, Volume 35, Issue 5Author(s): Marco Proietti, Deirdre A. Lane, Giuseppe Boriani, Gregory Y.H. LipAbstractIn recent years the management of atrial fibrillation patients has progressively and substantially changed because of the introduction of new treatments and the availability of new data regarding the epidemiology and clinical management of these patients. In the past 2 years alone, there have been 7 new guidelines or guideline updates that have been published, which have introduced new recommendations and significantly revised previously published ones. Tw...
Source: Canadian Journal of Cardiology - April 27, 2019 Category: Cardiology Source Type: research

Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease
In this study, we used a well-validated visual assessment to clinically rate scans as being amyloid positive or negative (38). As there is not an accepted threshold based on standardized centiloid reference regions, we defined an amyloid positivity centiloid cut-off threshold in our sample. Our cut-off (CL = 31.3, SUVR = 1.21) corresponds well to the estimated value proposed by Rowe and colleagues (34) in the context of AD (CL = 25–30), however our estimated threshold may be biased by the low number of Aβ positive patients. Our results suggest a lower prevalence of amyloid-positive PDD individuals than in ...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Ambient Conditions Prior to Tokyo 2020 Olympic and Paralympic Games: Considerations for Acclimation or Acclimatization Strategies
This study was supported by ZonMw (Project: Thermo Tokyo: Beat the heat), Netherlands Organisation for Scientific Research (NWO) (Project: Citius, Altius, Sanius), and Heatshield, under EU Horizon 2020 grant agreement No 668786. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments The authors thank Dr. Tatsuro Amano (Niigata University, Japan) for his assistance with translating the Japanese Meteorological Agency website. Footnotes ^ https://rdrr.io/g...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

Local experience with methamphetamine associated stroke at a small district health board.
Authors: Mahawish KM, Bowers A, DeCaigney S Abstract PMID: 30703785 [PubMed - in process]
Source: New Zealand Medical Journal - February 2, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Why the new 'living' Australian Stroke Guidelines matter to New Zealand.
Authors: Mahawish K, Barber PA, McRae A, Slark J, Ranta AA Abstract PMID: 30543606 [PubMed - in process]
Source: New Zealand Medical Journal - December 14, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Publication date: Available online 1 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Joseph S. Hudson, Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, David M. HasanAbstractEmergent stroke is mostly evaluated using hospital based imaging. Quick imaging allows for rapid administration of IV thrombolysis and outcome improvement. Microwave imaging (MI) is an emerging portable imaging modality. Iron oxide nanoparticles are known to interact with microwave frequency electromagnetic radiation. In this manuscript, we provide proof of concept for a novel iron oxide nanoparticle enhance...
Source: Journal of Clinical Neuroscience - November 2, 2018 Category: Neuroscience Source Type: research

Standards of practice in acute ischemic stroke intervention: International recommendations: This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et  al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287.
This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287. Interv Neuroradiol. 2018 Oct 23;:1591019918800457 Authors: Pierot L, Jayaraman MV, Szikora I, Hirsch JA, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, Rowley HA, Sanelli PC, Tampieri D, Brouwer PA, Fiehler J, Kocer N, Vilela P, Rovira A, Fischer U, Caso V, van der Worp B, Saka...
Source: Interventional Neuroradiology - October 27, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Stroke reperfusion treatment in regional New Zealand.
Authors: Lallu BD, Brebner AC, Pepperell B, Blume R, Langridge J, Caswell S, Webb H Abstract PMID: 30359360 [PubMed - in process]
Source: New Zealand Medical Journal - October 27, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Endovascular clot retrieval for acute ischaemic stroke in New Zealand.
CONCLUSIONS: This study has shown that stroke endovascular clot retrieval is being provided safely and effectively in New Zealand. However, there remain discrepancies in service provision, and ongoing regional, inter-regional and inter-sector collaboration is essential to implement comprehensive and equitable ECR services across the country. PMID: 30359351 [PubMed - in process]
Source: New Zealand Medical Journal - October 27, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Predictive values of pulse pressure variation and stroke volume variation for fluid responsiveness in patients with pneumoperitoneum
AbstractAnimal studies suggest that dynamic predictors remain useful in patients with pneumoperitoneum, but human data is conflicting. Our aim was to determine predictive values of pulse pressure variation (PPV) and stroke volume variation (SVV) in patients with pneumoperitoneum using LiDCORapid ™ haemodynamic monitor. Standardised fluid challenges of colloid were administered to patients undergoing laparoscopic procedures, one fluid challenge per patient. Intra-abdominal pressure was automatically held at 12  mmHg. Fluid responsiveness was defined as an increase in nominal stroke index (nSI) ≥ 10%. Linear regress...
Source: Journal of Clinical Monitoring and Computing - October 1, 2018 Category: Information Technology Source Type: research

Perioperative ischaemic stroke in patients with atrial fibrillation after temporary cessation of anticoagulation for elective surgery.
Authors: Xu Y, Maddula M PMID: 30235195 [PubMed - in process]
Source: New Zealand Medical Journal - September 21, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Predictive values of pulse pressure variation and stroke volume variation for fluid responsiveness in patients with pneumoperitoneum
AbstractAnimal studies suggest that dynamic predictors remain useful in patients with pneumoperitoneum, but human data is conflicting. Our aim was to determine predictive values of pulse pressure variation (PPV) and stroke volume variation (SVV) in patients with pneumoperitoneum using LiDCORapid ™ haemodynamic monitor. Standardised fluid challenges of colloid were administered to patients undergoing laparoscopic procedures, one fluid challenge per patient. Intra-abdominal pressure was automatically held at 12  mmHg. Fluid responsiveness was defined as an increase in nominal stroke index (nSI) ≥ 10%. Linear regress...
Source: Journal of Clinical Monitoring and Computing - August 28, 2018 Category: Information Technology Source Type: research

Activity monitors for increasing physical activity in adult stroke survivors.
CONCLUSIONS: Only four small RCTs with 274 participants (three in inpatient rehabilitation and one in the community) have examined the efficacy of activity monitors for increasing physical activity after stroke. Although these studies showed activity monitors could be incorporated into practice, there is currently not enough evidence to support the use of activity monitors to increase physical activity after stroke. PMID: 30051462 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 27, 2018 Category: General Medicine Authors: Lynch EA, Jones TM, Simpson DB, Fini NA, Kuys SS, Borschmann K, Kramer S, Johnson L, Callisaya ML, Mahendran N, Janssen H, English C, ACTIOnS Collaboration Tags: Cochrane Database Syst Rev Source Type: research

Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
This report presents a secondary analysis, and follow-up is complete.FindingsBetween May, 2001, and October, 2008, 1713 patients were enrolled and randomly allocated treatment (855 were assigned stenting and 858 endarterectomy), of whom 1530 individuals were followed up with ultrasound (737 assigned stenting and 793 endarterectomy) for a median of 4·0 years (IQR 2·3–5·0). At least moderate restenosis (≥50%) occurred in 274 patients after stenting (cumulative 5-year risk 40·7%) and in 217 after endarterectomy (29·6%; unadjusted hazard ratio [HR] 1·43, 95% CI 1·21–1·72; p<0·0001). Patients with at least mo...
Source: The Lancet Neurology - July 10, 2018 Category: Neurology Source Type: research

Projected stroke volumes to provide a 10-year direction for New Zealand stroke services.
CONCLUSION: Efforts to optimise stroke service performance and, increasingly, stroke prevention are required to ensure that the New Zealand Health Service will be able to manage the increased volumes of patients. Better data is required to validate the presented figures, which are largely based on unvalidated health administrative data. PMID: 29927912 [PubMed - in process]
Source: New Zealand Medical Journal - June 22, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Organised stroke care to improve survival and independence: New Zealand perspectives.
Authors: Weatherall M PMID: 29927911 [PubMed - in process]
Source: New Zealand Medical Journal - June 22, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Prevent 2nd Stroke: a pilot study of an online secondary prevention program for stroke survivors.
CONCLUSIONS: The results indicated that online programs are an acceptable way to address these health outcomes. Implications to public health: Further research is needed to assess the effectiveness of these interventions using powered trials. PMID: 29888829 [PubMed - as supplied by publisher]
Source: Australian and New Zealand Journal of Public Health - June 11, 2018 Category: International Medicine & Public Health Authors: Denham AMJ, Halpin S, Twyman L, Guillaumier A, Bonevski B Tags: Aust N Z J Public Health Source Type: research

Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
This report presents a secondary analysis, and follow-up is complete. Findings Between May, 2001, and October, 2008, 1713 patients were enrolled and randomly allocated treatment (855 were assigned stenting and 858 endarterectomy), of whom 1530 individuals were followed up with ultrasound (737 assigned stenting and 793 endarterectomy) for a median of 4·0 years (IQR 2·3–5·0). At least moderate restenosis (≥50%) occurred in 274 patients after stenting (cumulative 5-year risk 40·7%) and in 217 after endarterectomy (29·6%; unadjusted hazard ratio [HR] 1·43, 95% CI 1·21–1·72; p&lt;0·0001). Patients with at lea...
Source: The Lancet Neurology - June 1, 2018 Category: Neurology Source Type: research

Tenecteplase versus alteplase in acute ischemic stroke: systematic review and meta-analysis
AbstractTenecteplase is a product of genetic modification of recombinant tissue plasminogen activator with superior pharmacodynamic and pharmacokinetic properties. This meta-analysis was to determine whether intravenous thrombolysis with tenecteplase in patients with acute ischemic stroke has better efficacy and safety outcomes than with intravenous alteplase. PubMed, Cochrane Central Register of Controlled Trials, WHO International clinical trials registry platform (ICTRP), Australian New Zealand Clinical Trials Registry (ANZCTR), EU Clinical Trials Register (EU-CTR) and ClinicalTrials.gov were searched for trials compari...
Source: Acta Neurologica Belgica - May 4, 2018 Category: Neurology Source Type: research

The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit
AbstractCough reflex testing has been evaluated as a component of the clinical swallowing assessment as a means of identifying patients at risk of aspiration during swallowing. A previous study by our research group found good sensitivity and specificity of the cough reflex test for identifying patients at risk of aspiration post-stroke, yet its use did not decrease pneumonia rates, contrary to previous reports. The aim of this study was to expand on our earlier work by implementing a clinical management protocol incorporating cough reflex testing within the same healthcare setting and compare patient outcomes to those fro...
Source: Translational Stroke Research - March 30, 2018 Category: Neurology Source Type: research

Will new pill to stop a clot save me from a stroke?  
I have recently been prescribed Pradaxa to prevent clots and have been told there is a 3 per cent chance of me having a stroke. Is this a high risk, asks  Lionel Jenkins, New Zealand
Source: the Mail online | Health - December 19, 2017 Category: Consumer Health News Source Type: news

Inequities in access to inpatient rehabilitation after stroke: an international scoping review.
Conclusion Recommendations regarding which patients with moderate and severe strokes should access ongoing rehabilitation are inconsistent. Clinical practice guidelines from different countries regarding post-stroke rehabilitation do not always reflect the evidence regarding the likely benefits to people with stroke. Inequity in access to rehabilitation after stroke is an international issue. PMID: 28835194 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 23, 2017 Category: Neurology Authors: Lynch EA, Cadilhac DA, Luker JA, Hillier SL Tags: Top Stroke Rehabil Source Type: research

Dodecafluoropentane Improves Neurological Function Following Anterior Ischemic Stroke
This study investigated shortened dosage schedules of DDFPe in nonstandard posterior (NSTND) strokes following occlusions of the posterior cerebral arteries. DDFPe given at shortened schedules of 30 or 60-min injection intervals will reduce neurological deficits, percent stroke volume (%SV), and serum glutamate levels in NSTND ischemic strokes. New Zealand White rabbits (N = 26) were randomly placed into three groups: A (n = 9) controls given saline injections every 60 min, B (n = 9) 2 % DDFPe given IV every 30 min, and C (n = 8) DDFPe every 60 min. Injections began 1 h after embolization. Groups were subdivid...
Source: Molecular Neurobiology - July 13, 2017 Category: Neurology Source Type: research

A cautionary perspective on the utility of the RoPE score in cryptogenic stroke patients with a patent foramen ovale.
Authors: Boon KJ, Bridgman P PMID: 28694541 [PubMed - in process]
Source: New Zealand Medical Journal - July 13, 2017 Category: General Medicine Tags: N Z Med J Source Type: research

Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial
Publication date: Available online 27 June 2017 Source:The Lancet Author(s): The ATTEND Collaborative GroupR ILindleyC SAndersonLBillotAForsterM LHackettL AHarveySJanQLiHLiuPLanghorneP KMaulikG V SMurthyM FWalkerJ DPandianMAlimCFelixASyrigapuD KTugnawatS JVermaB RShamannaGHankeyJBernhardtM MMehndirattaLJeyaseelanPDonnellyDByrneSSteleyVSanthoshSChilappagariJMysoreJRoyM VPadmaLJohnSAaronN CBorahPVijayaSKaulDKhuranaP NSylajaD SHalprashanthB KMadhusudhanVNambiarSSureshbabuM CKhannaG SNarangDChakrabortyS SChakrabortyBBiswasSKauraHKoundalPSinghAAndriasD SThambuIRamyaJGeorgeA TPrabhakarPKirubakaranPAnbalaganMGhoseKBordoloiPGohai...
Source: The Lancet - June 28, 2017 Category: General Medicine Source Type: research

Provision of stroke thrombolysis services in New Zealand: changes between 2011 and 2016.
CONCLUSION: While there have been improvements in the provision of stroke thrombolysis throughout New Zealand, regional variations in service quality remains. The needs for better solutions to geographical barriers and formal training must be addressed as priorities. PMID: 28384148 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Trends in New Zealand stroke thrombolysis treatment rates.
CONCLUSIONS: There have been improvements in stroke thrombolysis rates and treatment delays in New Zealand hospitals since the institution of the National Stroke Network thrombolysis register. The Network will continue to adjust key performance indicators, and stroke thrombolysis targets for individual DHBs have been increased to 8% for 2017 and 10% for 2018. PMID: 28384147 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Improvements in acute stroke treatments in New Zealand-no one should be left behind.
Authors: Fink J PMID: 28384140 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Stroke thrombolysis in New Zealand: data from the first 6 months of the New Zealand Thrombolysis Register.
Authors: Joshi P, Fink J, Barber PA, Davis A, Lanford J, Seymour A, Wright P, Busby W, Abernethy G, Ranta AA Abstract The New Zealand National Stroke Network introduced a National Stroke Thrombolysis Register on the first of January 2015 to assist with quality assurance and continuous service improvement. In the first 6 months, there were 179 [75 women, mean (SD) age 69.9 (14) years] treated with stroke thrombolysis out of a total of 2,796 ischaemic stroke patients, giving a national thrombolysis rate of 6.4%. The median [Inter-quartile range (IQR)] onset-to-treatment time was 154 (125-190) minutes, and the median ...
Source: New Zealand Medical Journal - July 25, 2016 Category: Journals (General) Tags: N Z Med J Source Type: research

What influences the implementation of the New Zealand stroke guidelines for physiotherapists and occupational therapists?
Conclusion Alignment to the guidelines in NZ is influenced both positively and negatively by a range of interacting factors, consistent with other studies. Alignment might be improved by the introduction of some relatively simple strategies, such as ring-fencing time for access to resources and training in the use of the guidelines. Many of the barriers and related interventions are likely to be more complex. Implications for rehabilitation Alignment with stroke guidelines has been shown to improve patient outcomes. Therapist alignment with the implementation of the New Zealand stroke guidelines is influenced by guideline ...
Source: Disability and Rehabilitation - March 4, 2016 Category: Rehabilitation Authors: Mudge S, Hart A, Murugan S, Kersten P Tags: Disabil Rehabil Source Type: research

Stroke Awareness and Knowledge in an Urban New Zealand Population
This study assessed the awareness of stroke risk, symptoms, detection, and prevention behaviors in an urban New Zealand population.
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2015 Category: Neurology Authors: Jacquie L. Bay, Ana-Mishel Spiroski, Laura Fogg-Rogers, Clare M. McCann, Richard L.M. Faull, Peter A. Barber Source Type: research