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Total 98 results found since Jan 2013.

Dynamic Arterial Elastance During Experimental Endotoxic Septic Shock: A Potential Marker of Cardiovascular Efficiency
Dynamic arterial elastance (Eadyn), the ratio between pulse pressure variation (PPV) and stroke volume variation (SVV), has been suggested as a dynamic parameter relating pressure and flow. We aimed to determine the effects of endotoxic septic shock and hemodynamic resuscitation on Eadyn in an experimental study in 18 New Zealand rabbits. Animals received placebo (SHAM, n = 6) or intravenous lipopolysaccharide (E. Coli 055:B5, 1 mg⋅kg–1) with or without (EDX-R, n = 6; EDX, n = 6) hemodynamic resuscitation (fluid bolus of 20 ml⋅kg–1 and norepinephrine for restoring mean arterial pressure). Continuous arterial pressu...
Source: Frontiers in Physiology - October 1, 2020 Category: Physiology Source Type: research

Excess Stroke Deaths in Kidney Transplant Recipients: A Retrospective Population-based Cohort Study Using Data Linkage
Conclusions. Kidney transplant recipients had excess stroke deaths, particularly at younger ages and women. Preexisting cerebrovascular disease was a potentially modifiable risk factor for stroke death, suggesting further studies of secondary stroke prevention for kidney transplant recipients.
Source: Transplantation - September 24, 2020 Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research

Ethnic Differences in Access to Stroke Reperfusion Therapy in Northern New Zealand
Conclusions: This study has shown equitable access to acute stroke reperfusion therapies and largely similar outcomes in different ethnic groups in northern New Zealand.Neuroepidemiology
Source: Neuroepidemiology - September 21, 2020 Category: Epidemiology Source Type: research

The association between carotid atherosclerosis and treatment with lithium and antipsychotics in patients with bipolar disorder.
CONCLUSION: Lithium treatment may be associated with less progression in carotid intima-media thickness and the reduced risk for atherosclerosis in adults with bipolar disorder, including those with high cardiovascular disease risk. In addition to age and body mass index, antipsychotics may increase carotid intima-media thickness even in the low cardiovascular disease-risk patients. PMID: 32900219 [PubMed - as supplied by publisher]
Source: The Australian and New Zealand Journal of Psychiatry - September 7, 2020 Category: Psychiatry Authors: Tsai SY, Shen RS, Kuo CJ, Chen PH, Chung KH, Hsiao CY, Huang SH Tags: Aust N Z J Psychiatry Source Type: research

Atrial fibrillation in acute coronary syndrome: patient characteristics and appropriate utilisation of anti-thrombotic therapy in New Zealand (ANZACS-QI 39).
CONCLUSION: In New Zealand, one in seven patients presenting with ACS have AF, a third being new-onset AF. Antithrombotic management is inconsistent, with underutilisation of anticoagulants, particularly the DAT regimen, and is inadequately informed by stroke and bleeding risk scores. PMID: 32777794 [PubMed - in process]
Source: New Zealand Medical Journal - August 12, 2020 Category: General Medicine Tags: N Z Med J Source Type: research

Weekend carotid endarterectomies are not associated with a greater risk of stroke and/or death in Australia and New Zealand
Data from multiple surgical studies and settings have reported an increase in adverse events in patients admitted or treated over weekends. The aim of this study was to investigate short-term outcomes for patients undergoing carotid endarterectomy (CEA) in Australia and New Zealand based on the day of surgery.
Source: Annals of Vascular Surgery - August 11, 2020 Category: Surgery Authors: Noha Ferrah, Stuart Robert Walker Tags: Clinical Research, Basic Science Source Type: research

Assessment of image quality and dose in contrast-enhanced head and neck CT angiography of New Zealand rabbit.
CONCLUSIONS: Low dose CTA of rabbits with 70 or 80 kVp is feasible in a 256-slice or a 64-slice CT scanner. The radiation dose from the 256-slice CTA was much lower than that from the 64-slice CTA with comparable SNR and CNR. The technique can be further applied in longitudinal monitoring of an animal stroke model in the future. PMID: 32597826 [PubMed - as supplied by publisher]
Source: Journal of X-Ray Science and Technology - July 1, 2020 Category: Radiology Tags: J Xray Sci Technol Source Type: research

Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure.
CONCLUSIONS: Neither low perfusion pressure nor low perfusion flow during cardiopulmonary bypass were predictive of postoperative acute kidney injury, stroke or death. PMID: 32515271 [PubMed - as supplied by publisher]
Source: Perfusion - June 8, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Turner L, Hardikar A, Jose MD, Bhattarai K, Fenton C, Sharma R, Kirkland G, Jeffs L, Breslin M, Silva Ragaini B, Newland RF Tags: Perfusion Source Type: research

Peripheral Electrical Stimulation Paired With Movement-Related Cortical Potentials Improves Isometric Muscle Strength and Voluntary Activation Following Stroke
ConclusionA single session of ePAS can significantly increase isometric muscle strength and VA in people with chronic stroke. The findings confirm that ePAS has a central neuromodulatory mechanism and support further exploration of its potential as an adjunct to stroke rehabilitation. In addition, the findings offer alternative, feasible outcome measures for future research.Clinical trial registrationAustralia New Zealand Clinical Trials Registry ACTRN12617000838314 (www.anzctr.org.au), Universal Trial Number U111111953714.
Source: Frontiers in Human Neuroscience - May 14, 2020 Category: Neuroscience Source Type: research

Intensive care admissions and outcomes associated with short-term exposure to ambient air pollution: a time series analysis
ConclusionsIncreased ICU mortality was associated with higher levels of PM2.5. Larger studies are required to determine if the frequency of ICU admissions is positively associated with short-term exposure to air pollution.
Source: Intensive Care Medicine - April 29, 2020 Category: Intensive Care Source Type: research

Opposing Associations of Stress and Resilience With Functional Outcomes in Stroke Survivors in the Chronic Phase of Stroke: A Cross-Sectional Study
Stroke survivors report significant levels of psychological distress post stroke. To date, most studies conducted have focused on the relationship between psychological stress and functional outcomes in the acute phase of stroke. However, no studies had considered the role of stress over the chronic phase, where stress may continue to exert negative effects on cognitive and psychological processes. Further, the role of potentially modulatory variables, such as psychological resilience, on stroke outcomes has been understudied. The purpose of this study was to consider the relationships between stress and resilience with fu...
Source: Frontiers in Neurology - April 21, 2020 Category: Neurology Source Type: research

Bilateral vertebral artery dissection and cerebellar stroke: a rare complication of massage.
We describe the case of a 39-year-old male, who presented to our emergency department after a one-day history of headache and vomiting, with associated sudden onset posterior neck pain and cerebellar signs following a massage. Computed tomography angiogram and brain demonstrated bilateral vertebral artery dissection and cerebellar stroke. He was admitted to hospital for monitoring and conservative management with antiplatelet therapy, resulting in a good outcome. This is the first reported case of bilateral vertebral artery dissection and stroke to be associated with massage. This case also suggests, unlike many reports in...
Source: New Zealand Medical Journal - April 5, 2020 Category: General Medicine Tags: N Z Med J Source Type: research

Trial removal of indwelling urinary catheters in stroke patients: a clinical audit at North Shore Hospital.
CONCLUSIONS: Insufficient documentation and inappropriate indications for IDC insertion were features noted during this audit. Daily electronic reminders and prompting concerning TROC are important to reduce catheter days and reduce infection rates. Indwelling catheters and associated infections impact the length of hospitalisation, mortality and morbidity of stroke patients. PMID: 32242174 [PubMed - in process]
Source: New Zealand Medical Journal - April 5, 2020 Category: General Medicine Tags: N Z Med J Source Type: research

Cardiovascular and respiratory effects of carbon dioxide pneumoperitoneum in the domestic rabbit (Oryctolagus cuniculus).
In conclusion, pneumoperitoneum with carbon dioxide causes an increase in ETCO2, PaCO2, and PIP, whereas cardiac output and CI decrease. These cardiorespiratory changes should be considered when determining the optimal IAP for laparoscopic procedures in rabbits. PMID: 32255905 [PubMed - in process]
Source: Canadian Journal of Veterinary Research - March 31, 2020 Category: Veterinary Research Authors: Kabakchiev C, Valverde A, Singh A, Beaufrère H Tags: Can J Vet Res Source Type: research

Inducing ketogenesis via an enteral formulation in patients with acute brain injury:a phase II study.
Conclusion: In patients with acute brain injury, an enterally administered ketogenic formulation increased plasma ketone concentrations, was well tolerated, did not impact on cerebral hemodynamics and can be safely administered.Clinical trial registered at the Australian New Zealand Clinical Trials Registry (ACTRN12616000332426)Abbreviations: BHB: betahydroxybutyrate; AcAc: acetoacetate; ABI: acute brain injury; TBI: traumatic brain injury; CSF: cerebrospinal fluid; SAH: subarachnoid injury; CVA: cerebrovascular accidents; ICP: intracranial pressure; CPP: cerebral perfusion pressure; ICU: intensive care unit; EVD: external...
Source: Neurological Research - February 28, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Community Knowledge and Awareness of Stroke in New Zealand
Introduction: Community knowledge and stroke awareness is crucial for primary prevention of stroke and timely access to stroke treatments including acute reperfusion therapies. We conducted a national telephone survey to quantify the level of community stroke awareness. Methods: A random sample of 400 adults in New Zealand (NZ), stratified by the 4 main ethnic groups, was surveyed. Eligible participants answered stroke awareness questions using both unprompted (open-ended) and prompted questions (using a list).
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2019 Category: Neurology Authors: Rita V. Krishnamurthi, Suzanne Barker-Collo, Peter Alan Barber, Lynette J. Tippett, John C. Dalrymple-Alford, Bronwyn Tunnage, Susan Mahon, Priyakumari G. Parmar, Melanie Moylan, Valery L. Feigin Source Type: research

Incidence of stroke and traumatic brain injury in New Zealand: contrasting the BIONIC and ARCOS-IV studies.
CONCLUSIONS: Differences in TBI and stroke incidence suggest targeting prevention very differently for the two groups. Incidence profiles suggest TBI is much more common; and a need to target males and those of Māori ethnicity for TBI prevention. PMID: 31563926 [PubMed - in process]
Source: New Zealand Medical Journal - October 1, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia).
Abstract Utstein-style reporting templates provide a structured framework with which to compare systems of care for cardiac arrest. The 2004 Utstein reporting template encompassed both out-of-hospital and in-hospital cardiac arrest. A 2015 update of the Utstein template focused on out-of-hospital cardiac arrest, which makes this update of the in-hospital template timely. Representatives of the International Liaison Committee on Resuscitation developed an updated in-hospital Utstein reporting template iteratively by meeting face-to-face, by teleconference, and by online surveys between 2013 and 2018. Data elements ...
Source: Circulation - September 15, 2019 Category: Cardiology Authors: Nolan JP, Berg RA, Andersen LW, Bhanji F, Chan PS, Donnino MW, Lim SH, Ma MH, Nadkarni VM, Starks MA, Perkins GD, Morley PT, Soar J, Utstein Collaborators Tags: Circulation Source Type: research

Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom Scores.
Conclusions: We provide evidence that fALFF is sensitive to changes in poststroke depressive symptom severity and implicates frontostriatal and cerebellar regions, consistent with previous studies. The use of multiband analysis could be an effective method to examine neural correlates of depression after stroke. The START-PrePARE trial is registered with the Australian New Zealand Clinical Trial Registry, number ACTRN12610000987066. PMID: 31467520 [PubMed - in process]
Source: Neural Plasticity - August 31, 2019 Category: Neurology Authors: Goodin P, Lamp G, Vidyasagar R, Connelly A, Rose S, Campbell BCV, Tse T, Ma H, Howells D, Hankey GJ, Davis S, Donnan G, Carey LM Tags: Neural Plast Source Type: research

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
Publication date: Available online 15 August 2019Source: The LancetAuthor(s): Marko Mrkobrada, Matthew T.V. Chan, David Cowan, Douglas Campbell, Chew Yin Wang, David Torres, German Malaga, Robert D. Sanders, Manas Sharma, Carl Brown, Alben Sigamani, Wojciech Szczeklik, Mukul Sharma, Gordon Guyatt, Eric E. Smith, Ronit Agid, Adam A. Dmytriw, Jessica Spence, Nikesh R. Adunuri, Flavia K. BorgesSummaryBackgroundIn non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac surgery and is associated with ...
Source: The Lancet - August 16, 2019 Category: General Medicine Source Type: research

How much rehabilitation are our patients with stroke receiving?
CONCLUSION: There were delays in providing an initial community rehabilitation appointment and insufficient therapy intensity when comparing audit results to New Zealand Guideline expectations. As a result of this audit, recommendations for service improvements have been made. PMID: 31352474 [PubMed - in process]
Source: New Zealand Medical Journal - July 30, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Local experience with methamphetamine associated stroke at a small district health board.
Authors: Mahawish KM, Bowers A, DeCaigney S Abstract PMID: 30703785 [PubMed - in process]
Source: New Zealand Medical Journal - February 2, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Why the new 'living' Australian Stroke Guidelines matter to New Zealand.
Authors: Mahawish K, Barber PA, McRae A, Slark J, Ranta AA Abstract PMID: 30543606 [PubMed - in process]
Source: New Zealand Medical Journal - December 14, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Publication date: Available online 1 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Joseph S. Hudson, Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, David M. HasanAbstractEmergent stroke is mostly evaluated using hospital based imaging. Quick imaging allows for rapid administration of IV thrombolysis and outcome improvement. Microwave imaging (MI) is an emerging portable imaging modality. Iron oxide nanoparticles are known to interact with microwave frequency electromagnetic radiation. In this manuscript, we provide proof of concept for a novel iron oxide nanoparticle enhance...
Source: Journal of Clinical Neuroscience - November 2, 2018 Category: Neuroscience Source Type: research

Standards of practice in acute ischemic stroke intervention: International recommendations: This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et  al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287.
This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287. Interv Neuroradiol. 2018 Oct 23;:1591019918800457 Authors: Pierot L, Jayaraman MV, Szikora I, Hirsch JA, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, Rowley HA, Sanelli PC, Tampieri D, Brouwer PA, Fiehler J, Kocer N, Vilela P, Rovira A, Fischer U, Caso V, van der Worp B, Saka...
Source: Interventional Neuroradiology - October 27, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Stroke reperfusion treatment in regional New Zealand.
Authors: Lallu BD, Brebner AC, Pepperell B, Blume R, Langridge J, Caswell S, Webb H Abstract PMID: 30359360 [PubMed - in process]
Source: New Zealand Medical Journal - October 27, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Endovascular clot retrieval for acute ischaemic stroke in New Zealand.
CONCLUSIONS: This study has shown that stroke endovascular clot retrieval is being provided safely and effectively in New Zealand. However, there remain discrepancies in service provision, and ongoing regional, inter-regional and inter-sector collaboration is essential to implement comprehensive and equitable ECR services across the country. PMID: 30359351 [PubMed - in process]
Source: New Zealand Medical Journal - October 27, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Predictive values of pulse pressure variation and stroke volume variation for fluid responsiveness in patients with pneumoperitoneum
AbstractAnimal studies suggest that dynamic predictors remain useful in patients with pneumoperitoneum, but human data is conflicting. Our aim was to determine predictive values of pulse pressure variation (PPV) and stroke volume variation (SVV) in patients with pneumoperitoneum using LiDCORapid ™ haemodynamic monitor. Standardised fluid challenges of colloid were administered to patients undergoing laparoscopic procedures, one fluid challenge per patient. Intra-abdominal pressure was automatically held at 12  mmHg. Fluid responsiveness was defined as an increase in nominal stroke index (nSI) ≥ 10%. Linear regress...
Source: Journal of Clinical Monitoring and Computing - October 1, 2018 Category: Information Technology Source Type: research

Perioperative ischaemic stroke in patients with atrial fibrillation after temporary cessation of anticoagulation for elective surgery.
Authors: Xu Y, Maddula M PMID: 30235195 [PubMed - in process]
Source: New Zealand Medical Journal - September 21, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Predictive values of pulse pressure variation and stroke volume variation for fluid responsiveness in patients with pneumoperitoneum
AbstractAnimal studies suggest that dynamic predictors remain useful in patients with pneumoperitoneum, but human data is conflicting. Our aim was to determine predictive values of pulse pressure variation (PPV) and stroke volume variation (SVV) in patients with pneumoperitoneum using LiDCORapid ™ haemodynamic monitor. Standardised fluid challenges of colloid were administered to patients undergoing laparoscopic procedures, one fluid challenge per patient. Intra-abdominal pressure was automatically held at 12  mmHg. Fluid responsiveness was defined as an increase in nominal stroke index (nSI) ≥ 10%. Linear regress...
Source: Journal of Clinical Monitoring and Computing - August 28, 2018 Category: Information Technology Source Type: research

Activity monitors for increasing physical activity in adult stroke survivors.
CONCLUSIONS: Only four small RCTs with 274 participants (three in inpatient rehabilitation and one in the community) have examined the efficacy of activity monitors for increasing physical activity after stroke. Although these studies showed activity monitors could be incorporated into practice, there is currently not enough evidence to support the use of activity monitors to increase physical activity after stroke. PMID: 30051462 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 27, 2018 Category: General Medicine Authors: Lynch EA, Jones TM, Simpson DB, Fini NA, Kuys SS, Borschmann K, Kramer S, Johnson L, Callisaya ML, Mahendran N, Janssen H, English C, ACTIOnS Collaboration Tags: Cochrane Database Syst Rev Source Type: research

Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
This report presents a secondary analysis, and follow-up is complete.FindingsBetween May, 2001, and October, 2008, 1713 patients were enrolled and randomly allocated treatment (855 were assigned stenting and 858 endarterectomy), of whom 1530 individuals were followed up with ultrasound (737 assigned stenting and 793 endarterectomy) for a median of 4·0 years (IQR 2·3–5·0). At least moderate restenosis (≥50%) occurred in 274 patients after stenting (cumulative 5-year risk 40·7%) and in 217 after endarterectomy (29·6%; unadjusted hazard ratio [HR] 1·43, 95% CI 1·21–1·72; p<0·0001). Patients with at least mo...
Source: The Lancet Neurology - July 10, 2018 Category: Neurology Source Type: research

Projected stroke volumes to provide a 10-year direction for New Zealand stroke services.
CONCLUSION: Efforts to optimise stroke service performance and, increasingly, stroke prevention are required to ensure that the New Zealand Health Service will be able to manage the increased volumes of patients. Better data is required to validate the presented figures, which are largely based on unvalidated health administrative data. PMID: 29927912 [PubMed - in process]
Source: New Zealand Medical Journal - June 22, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Organised stroke care to improve survival and independence: New Zealand perspectives.
Authors: Weatherall M PMID: 29927911 [PubMed - in process]
Source: New Zealand Medical Journal - June 22, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

Prevent 2nd Stroke: a pilot study of an online secondary prevention program for stroke survivors.
CONCLUSIONS: The results indicated that online programs are an acceptable way to address these health outcomes. Implications to public health: Further research is needed to assess the effectiveness of these interventions using powered trials. PMID: 29888829 [PubMed - as supplied by publisher]
Source: Australian and New Zealand Journal of Public Health - June 11, 2018 Category: International Medicine & Public Health Authors: Denham AMJ, Halpin S, Twyman L, Guillaumier A, Bonevski B Tags: Aust N Z J Public Health Source Type: research

Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
This report presents a secondary analysis, and follow-up is complete. Findings Between May, 2001, and October, 2008, 1713 patients were enrolled and randomly allocated treatment (855 were assigned stenting and 858 endarterectomy), of whom 1530 individuals were followed up with ultrasound (737 assigned stenting and 793 endarterectomy) for a median of 4·0 years (IQR 2·3–5·0). At least moderate restenosis (≥50%) occurred in 274 patients after stenting (cumulative 5-year risk 40·7%) and in 217 after endarterectomy (29·6%; unadjusted hazard ratio [HR] 1·43, 95% CI 1·21–1·72; p&lt;0·0001). Patients with at lea...
Source: The Lancet Neurology - June 1, 2018 Category: Neurology Source Type: research

Tenecteplase versus alteplase in acute ischemic stroke: systematic review and meta-analysis
AbstractTenecteplase is a product of genetic modification of recombinant tissue plasminogen activator with superior pharmacodynamic and pharmacokinetic properties. This meta-analysis was to determine whether intravenous thrombolysis with tenecteplase in patients with acute ischemic stroke has better efficacy and safety outcomes than with intravenous alteplase. PubMed, Cochrane Central Register of Controlled Trials, WHO International clinical trials registry platform (ICTRP), Australian New Zealand Clinical Trials Registry (ANZCTR), EU Clinical Trials Register (EU-CTR) and ClinicalTrials.gov were searched for trials compari...
Source: Acta Neurologica Belgica - May 4, 2018 Category: Neurology Source Type: research

The Dysphagia in Stroke Protocol Reduces Aspiration Pneumonia in Patients with Dysphagia Following Acute Stroke: a Clinical Audit
AbstractCough reflex testing has been evaluated as a component of the clinical swallowing assessment as a means of identifying patients at risk of aspiration during swallowing. A previous study by our research group found good sensitivity and specificity of the cough reflex test for identifying patients at risk of aspiration post-stroke, yet its use did not decrease pneumonia rates, contrary to previous reports. The aim of this study was to expand on our earlier work by implementing a clinical management protocol incorporating cough reflex testing within the same healthcare setting and compare patient outcomes to those fro...
Source: Translational Stroke Research - March 30, 2018 Category: Neurology Source Type: research

Will new pill to stop a clot save me from a stroke?  
I have recently been prescribed Pradaxa to prevent clots and have been told there is a 3 per cent chance of me having a stroke. Is this a high risk, asks  Lionel Jenkins, New Zealand
Source: the Mail online | Health - December 18, 2017 Category: Consumer Health News Source Type: news

Inequities in access to inpatient rehabilitation after stroke: an international scoping review.
Conclusion Recommendations regarding which patients with moderate and severe strokes should access ongoing rehabilitation are inconsistent. Clinical practice guidelines from different countries regarding post-stroke rehabilitation do not always reflect the evidence regarding the likely benefits to people with stroke. Inequity in access to rehabilitation after stroke is an international issue. PMID: 28835194 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 23, 2017 Category: Neurology Authors: Lynch EA, Cadilhac DA, Luker JA, Hillier SL Tags: Top Stroke Rehabil Source Type: research

Dodecafluoropentane Improves Neurological Function Following Anterior Ischemic Stroke
This study investigated shortened dosage schedules of DDFPe in nonstandard posterior (NSTND) strokes following occlusions of the posterior cerebral arteries. DDFPe given at shortened schedules of 30 or 60-min injection intervals will reduce neurological deficits, percent stroke volume (%SV), and serum glutamate levels in NSTND ischemic strokes. New Zealand White rabbits (N = 26) were randomly placed into three groups: A (n = 9) controls given saline injections every 60 min, B (n = 9) 2 % DDFPe given IV every 30 min, and C (n = 8) DDFPe every 60 min. Injections began 1 h after embolization. Groups were subdivid...
Source: Molecular Neurobiology - July 13, 2017 Category: Neurology Source Type: research

A cautionary perspective on the utility of the RoPE score in cryptogenic stroke patients with a patent foramen ovale.
Authors: Boon KJ, Bridgman P PMID: 28694541 [PubMed - in process]
Source: New Zealand Medical Journal - July 13, 2017 Category: General Medicine Tags: N Z Med J Source Type: research

Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial
Publication date: Available online 27 June 2017 Source:The Lancet Author(s): The ATTEND Collaborative GroupR ILindleyC SAndersonLBillotAForsterM LHackettL AHarveySJanQLiHLiuPLanghorneP KMaulikG V SMurthyM FWalkerJ DPandianMAlimCFelixASyrigapuD KTugnawatS JVermaB RShamannaGHankeyJBernhardtM MMehndirattaLJeyaseelanPDonnellyDByrneSSteleyVSanthoshSChilappagariJMysoreJRoyM VPadmaLJohnSAaronN CBorahPVijayaSKaulDKhuranaP NSylajaD SHalprashanthB KMadhusudhanVNambiarSSureshbabuM CKhannaG SNarangDChakrabortyS SChakrabortyBBiswasSKauraHKoundalPSinghAAndriasD SThambuIRamyaJGeorgeA TPrabhakarPKirubakaranPAnbalaganMGhoseKBordoloiPGohai...
Source: The Lancet - June 28, 2017 Category: General Medicine Source Type: research

Provision of stroke thrombolysis services in New Zealand: changes between 2011 and 2016.
CONCLUSION: While there have been improvements in the provision of stroke thrombolysis throughout New Zealand, regional variations in service quality remains. The needs for better solutions to geographical barriers and formal training must be addressed as priorities. PMID: 28384148 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Trends in New Zealand stroke thrombolysis treatment rates.
CONCLUSIONS: There have been improvements in stroke thrombolysis rates and treatment delays in New Zealand hospitals since the institution of the National Stroke Network thrombolysis register. The Network will continue to adjust key performance indicators, and stroke thrombolysis targets for individual DHBs have been increased to 8% for 2017 and 10% for 2018. PMID: 28384147 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Improvements in acute stroke treatments in New Zealand-no one should be left behind.
Authors: Fink J PMID: 28384140 [PubMed - in process]
Source: New Zealand Medical Journal - April 8, 2017 Category: Journals (General) Tags: N Z Med J Source Type: research

Stroke thrombolysis in New Zealand: data from the first 6 months of the New Zealand Thrombolysis Register.
Authors: Joshi P, Fink J, Barber PA, Davis A, Lanford J, Seymour A, Wright P, Busby W, Abernethy G, Ranta AA Abstract The New Zealand National Stroke Network introduced a National Stroke Thrombolysis Register on the first of January 2015 to assist with quality assurance and continuous service improvement. In the first 6 months, there were 179 [75 women, mean (SD) age 69.9 (14) years] treated with stroke thrombolysis out of a total of 2,796 ischaemic stroke patients, giving a national thrombolysis rate of 6.4%. The median [Inter-quartile range (IQR)] onset-to-treatment time was 154 (125-190) minutes, and the median ...
Source: New Zealand Medical Journal - July 25, 2016 Category: Journals (General) Tags: N Z Med J Source Type: research

What influences the implementation of the New Zealand stroke guidelines for physiotherapists and occupational therapists?
Conclusion Alignment to the guidelines in NZ is influenced both positively and negatively by a range of interacting factors, consistent with other studies. Alignment might be improved by the introduction of some relatively simple strategies, such as ring-fencing time for access to resources and training in the use of the guidelines. Many of the barriers and related interventions are likely to be more complex. Implications for rehabilitation Alignment with stroke guidelines has been shown to improve patient outcomes. Therapist alignment with the implementation of the New Zealand stroke guidelines is influenced by guideline ...
Source: Disability and Rehabilitation - March 4, 2016 Category: Rehabilitation Authors: Mudge S, Hart A, Murugan S, Kersten P Tags: Disabil Rehabil Source Type: research

Stroke Awareness and Knowledge in an Urban New Zealand Population
This study assessed the awareness of stroke risk, symptoms, detection, and prevention behaviors in an urban New Zealand population.
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2015 Category: Neurology Authors: Jacquie L. Bay, Ana-Mishel Spiroski, Laura Fogg-Rogers, Clare M. McCann, Richard L.M. Faull, Peter A. Barber Source Type: research